Abstract: Administering medical digital images including receiving a request for an image processing transaction to process the medical digital image; storing the medical image in one or more medical image caches; creating a medical image business object representing the business transaction; storing the medical image business object in the medical image metadata database; selecting, in dependence upon workflow selection rules and the attributes of the medical image business object, one or more clinical workflows to process the medical image; processing the medical image of the request with the clinical workflows, thereby creating a resultant business object and resultant medical image; routing the resultant medical image to a destination.

Abstract: The present disclosure is directed to methods and systems for processing replacements to a target array by a plurality of source arrays. Selected tokens in a target array may be replaced with corresponding tokens from a source array to generate a region of identical tokens, which may be processed or removed. Tokens in the target array may be shifted in a direction corresponding to the source array to fill empty cells within the target array and new tokens generated. Selections may be made from multiple source arrays iteratively, with shift directions dynamically modified.

Abstract: This disclosure describes, in one aspect, a device for electrochemical quantitation of autoantibodies. Generally, the device includes a housing that defines a plurality of channels and at least two reaction zones. A first reaction zone includes a porous membrane and a first electrode assembly in fluid communication with a first channel. The first reaction zone also includes a first plurality of autoantigens immobilized to the porous membrane. The first electrode assembly is in communication with an amperometric reader. A second reaction zone includes a porous membrane and a second electrode assembly in fluid communication with a second channel. The second reaction zone includes a second plurality of autoantigens immobilized to the porous membrane. The second electrode assembly is in communication with the amperometric reader. Finally, the device includes a source of negative pressure in fluid communication with the first reaction zone and the second reaction zone.

Abstract: An m×l array of randomly selected tokens may be provided as a playing field, and a second n×l array of randomly selected tokens may be provided as a hand. The player may select a cell within the m×l array to replace the token in said cell with a token in a corresponding cell of the n×l array. If the replacement results in a region of adjacent identical tokens in the m×l array, the tokens may be removed and the player's score incremented. If no plays are possible from the player's hand, the player may draw a new hand of randomly selected tokens to replace the tokens and/or blank spaces in the n×l array. Play continues until the player has exhausted a predetermined number of opportunities to draw a new hand.

Abstract: An m×l array of randomly selected tokens may be provided as a playing field, and a second n×l array of randomly selected tokens may be provided as a hand. The player may select a cell within the m×l array to replace the token in said cell with a token in a corresponding cell of the n×l array. If the replacement results in a region of adjacent identical tokens in the m×l array, the tokens may be removed and the player's score incremented. If no plays are possible from the player's hand, the player may draw a new hand of randomly selected tokens to replace the tokens and/or blank spaces in the n×l array. Play continues until the player has exhausted a predetermined number of opportunities to draw a new hand.

Abstract: Administering a business transaction, including: receiving a request for a business transaction, the request containing data to be processed by the business transaction and metadata describing the data and the request; creating, in dependence upon classification rules, the data to be processed by the business transaction, and the metadata describing the data and the request, a business object representing the business transaction; selecting, in dependence upon workflow selection rules and attributes of the business object, one or more workflows to process the data to be processed by the business transaction; processing the data to be processed by the business transaction with the workflows, thereby creating a resultant business object and resultant data; and routing, in dependence upon content routing rules and the attributes of the resultant business object, the resultant data to a destination.

Abstract: Administering medical digital images including receiving a medical image business object representing a transaction carrying out a type of service request made by a health care provider; selecting, in dependence upon workflow selection rules and the attributes of the medical image business object, one or more clinical workflows to process the medical image according to the transaction; and processing the medical image of the request with the clinical workflows, thereby creating a resultant business object and resultant medical image including selecting, by the workflow dispatcher in dependence upon metadata for computational units in the distributed medical digital image computing environment, particular computational units in the distributed medical digital image computing environment to perform particular services of the one or more clinical workflows, deploying the particular services to the particular computational units, and executing the services on the computational units upon which they are deployed.

Abstract: Firearms with barrel cinching clamps have a receiver having a forward portion defining an internally threaded bore, a barrel having a threaded end removably received in the bore, at least a selected portion of the forward portion being split by a gap, the selected portion having connection elements on opposite sides of the gap, and an adjustable element connected to the connection elements and operable to narrow the gap to secure the barrel in the bore and to widen the gap to permit the barrel to be readily unscrewed from the bore. The bore may define a bore axis, and the gap may be parallel to the bore axis. A circumferentially complete portion of the threaded bore including a plurality of threads adjacent to the gap may be unbroken by a gap. The circumferentially complete portion of the threaded bore may be forward and/or rearward of the selected portion.

Abstract: A method for processing a discount for an off-peak transaction includes: receiving an off-peak offer, the offer including a merchant identifier, start time, end time, and transaction modifier; identifying an offer identifier; storing the offer with offer identifier; transmitting the stored offer; receiving a discount request, the request including a consumer identifier and offer identification; identifying a selected offer where the offer identifier matches the offer identification; receiving an authorization request including a consumer identification, merchant identification, transaction time, and transaction amount; calculating a new amount based on the transaction amount and the transaction modifier for the selected offer if the consumer identification matches the consumer identifier, the merchant identification matches the merchant identifier, and the transaction time is within the start and end times; and transmitting an authorization response for the new amount, where the response is for a final author

Abstract: An m×l array of randomly selected tokens may be provided as a playing field, and a second n×l array of randomly selected tokens may be provided as a hand. The player may select a cell within the m×l array to replace the token in said cell with a token in a corresponding cell of the n×l array. If the replacement results in a region of adjacent identical tokens in the m×l array, the tokens may be removed and the player's score incremented. If no plays are possible from the player's hand, the player may draw a new hand of randomly selected tokens to replace the tokens and/or blank spaces in the n×l array. Play continues until the player has exhausted a predetermined number of opportunities to draw a new hand.

Abstract: Managing failover operations on a cluster of computers, including: identifying, by a failover hold module, a failure to access data storage in the cluster of computers; preventing the execution of all read operations directed to the data storage that were received after the failure to access data storage was identified; executing all write operations directed to the data storage that were received after the failure to access data storage was identified, including writing data to a cache; identifying that a failover to alternative data storage is complete; executing the held read operations, including reading data from the alternative data storage; and copying, from cache to the alternative data storage, the data written to the cache as part of the write operations.

Abstract: Firearms with barrel cinching clamps have a receiver having a forward portion defining an internally threaded bore, a barrel having a threaded end removably received in the bore, at least a selected portion of the forward portion being split by a gap, the selected portion having connection elements on opposite sides of the gap, and an adjustable element connected to the connection elements and operable to narrow the gap to secure the barrel in the bore and to widen the gap to permit the barrel to be readily unscrewed from the bore. The bore may define a bore axis, and the gap may be parallel to the bore axis. A circumferentially complete portion of the threaded bore including a plurality of threads adjacent to the gap may be unbroken by a gap. The circumferentially complete portion of the threaded bore may be forward and/or rearward of the selected portion.

Abstract: Managing failover operations on a cluster of computers, including: identifying, by a failover hold module, a failure to access data storage in the cluster of computers; preventing the execution of all read operations directed to the data storage that were received after the failure to access data storage was identified; executing all write operations directed to the data storage that were received after the failure to access data storage was identified, including writing data to a cache; identifying that a failover to alternative data storage is complete; executing the held read operations, including reading data from the alternative data storage; and copying, from cache to the alternative data storage, the data written to the cache as part of the write operations.

Abstract: Methods, systems and articles of manufacture are disclosed for providing secure access to data. Public UDTFs, private UDTFs and a metadata processor are utilized to facilitate secure access to data residing in a variety of data repositories. User security attributes and UDTF attributes are gathered. A table is queried based on the gathered attributes.

Abstract: Techniques are provided for accessing data within data repositories. Public UDTFs, private UDTFs and a metadata processor are utilized to provide access to data residing in a variety of data repositories.

Abstract: The present invention generally provides methods, systems, and articles of manufacture for managing an annotation system that includes storing annotations for a document family, i.e., a series of versions of a data source. Annotations created for one version of the data source may be viewed in context from both subsequent and prior versions of the same data source. Embodiments of the invention associate annotations with both a data source “family identifier” as well as a “version identifier.” Other than adding a family ID to the data source, the data source remains unchanged. The family ID is maintained across different versions of the data source, whereas version IDs are determined for a specific version of the data source. Version IDs can be constructed from each data source directly, and do not need to be stored.

Abstract: The present invention provides a compound of formula (I) or a pharmaceutically acceptable salt thereof: wherein A is hydrogen, C1-4alkyl, C3-6cycloalkyl, C1-3alkoxy, C1-3alkoxy C1-4alkyl, C1-2fluoroalkyl, halogen, NR6R7, optionally substituted heteroaryl (Het), or optionally substituted phenyl, and R1, R2, R3, R4, R5, R6 and R7 are as defined in the description. The compounds or salts are thought to modulate P2X7 receptor function and to be capable of antagonizing the effects of ATP at the P2X7 receptor. The invention also provides the use of the compound or salt in the treatment or prophylaxis of, for example, inflammatory pain, neuropathic pain, visceral pain, rheumatoid arthritis or osteoarthritis or neurodegenerative disorders.

Abstract: A trace gas sensing apparatus includes a cathode, an anode, a vacuum enclosure, and a membrane. The anode coaxially surrounds the cathode, wherein the cathode and the anode define an annular ionization chamber. The vacuum enclosure surrounds the cathode and the anode and includes a gas inlet fluidly communicating with the ionization chamber. The membrane is coupled to the gas inlet in a sealed manner and is permselective to trace gas. The apparatus may further include circuitry for applying a negative voltage potential to the cathode and for measuring an ion current signal generated by the cathode, and a magnet assembly for generating a magnetic field in the ionization chamber. The cathode may include an elongated member located along a longitudinal axis, and first and second end plates orthogonal to the longitudinal axis.

Abstract: Methods, systems and articles of manufacture are disclosed for providing secure access to data. Public UDTFs, private UDTFs and a metadata processor are utilized to facilitate secure access to data residing in a variety of data repositories.

Abstract: Managing failover operations on a cluster of computers, including: identifying, by a failover hold module, a failure to access data storage in the cluster of computers; preventing the execution of all read operations directed to the data storage that were received after the failure to access data storage was identified; executing all write operations directed to the data storage that were received after the failure to access data storage was identified, including writing data to a cache; identifying that a failover to alternative data storage is complete; executing the held read operations, including reading data from the alternative data storage; and copying, from cache to the alternative data storage, the data written to the cache as part of the write operations.