Patents by Inventor David

David has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240368207
    Abstract: The present disclosure, among other things, provides technologies for oligonucleotide synthesis. In some embodiments, the present disclosure provides phosphoramidites and methods for synthesis thereof. In some embodiments, provided methods provides higher yields and/or purities. In some embodiments, provided methods remove byproducts without contact with an aqueous solution.
    Type: Application
    Filed: November 28, 2023
    Publication date: November 7, 2024
    Inventors: David Charles Donnell Butler, Pachamuthu Kandasamy, Subramanian Marappan, Ik-Hyeon Paik, Jayakanthan Kumarasamy, Gopal Reddy Bommineni
  • Publication number: 20240366599
    Abstract: The present disclose provides methods of treating NTM-PD and other bacterial infections, including pulmonary tuberculous and nontuberculous mycobacteria infections. Clinical studies have established the safety of SPR720 up to daily oral dosages of 2000 mg and shown that once daily oral dosing is sufficient to provide efficacious plasma levels of the active agent, SPR719. Clinical studies have also shown that there is no significant food effect for SPR720 and that the drug may be given in to a patient in the fed or fasted state. Clinical studies have also established that SPR720 can be administered safely to elderly patients. The present disclosure provides a method of treating a bacterial infection in a patient comprising administering a daily oral dose of SPR720, or a pharmaceutically acceptable salt thereof, the oral dose comprising 100 mg SPR720 to 1500 mg SPR720.
    Type: Application
    Filed: April 26, 2024
    Publication date: November 7, 2024
    Inventors: Angela TALLEY, David MELNICK
  • Publication number: 20240373157
    Abstract: Systems, methods, and non-transitory computer readable storage media for determining when to wirelessly communicatively couple together a pair of untethered wireless audio output devices, such as wireless ear buds, and for determining when to erase a connection history stored on one or both of the wireless audio output devices. Some embodiments of the present technology involve a wireless ear bud case for housing a pair of wireless ear buds.
    Type: Application
    Filed: May 13, 2024
    Publication date: November 7, 2024
    Inventors: Robert D. WATSON, David John SHAW, Ganesh Adkasthala GANAPATHI BATTA, Chandrahas Aralaguppe CHANDRAMOHAN, Gregory Robert BURNS, Benjamin Huth BYER
  • Publication number: 20240368180
    Abstract: The disclosure provides at least one entity chosen from compounds of Formula I, a tautomer thereof, a deuterated derivative of that compound or tautomer, and a pharmaceutically acceptable salt of any of the foregoing, compositions comprising the same, and methods of using the same, including uses in treating APOL1-mediated diseases, including pancreatic cancer, focal segmental glomerulosclerosis (FSGS), and/or non-diabetic kidney disease (NDKD).
    Type: Application
    Filed: November 8, 2023
    Publication date: November 7, 2024
    Inventors: Jun Myun AHN, Samantha ANGLE, Michael Aaron BRODNEY, Jingrong CAO, John E. COCHRAN, Jon H. COME, Leslie A. DAKIN, Elena DOLGIKH, Brad D. MAXWELL, Suganthini S. NANTHAKUMAR, Hardwin O'DOWD, Jessica Howard OLSEN, Timothy J. SENTER, Akira Joseph SHIMIZU, Steven David STONE, Haoxuan WANG
  • Publication number: 20240366327
    Abstract: Examples described herein are relevant to robotic surgical systems, such as those used in spine surgery. Examples described herein include: a distal section of a robot arm, pods having fiducials, face switching angles, fiducial hollows, drape anchoring and sensing, selective face switching with active fiducials, pedal-less workflow, user interface control, hand guiding, robot egress, robot tool center point adjustment, collision reaction, dynamic screw placement ordering, flexible robot cart placement, depth gauges, implant checking, implant-to-instrument-checking, robot bed-side docking, workflow based cart immobilization, patient gross movement monitoring, selective brake control, auto vertical adjustment, gesture-based planning, automatic sleeve retention and retraction, among others.
    Type: Application
    Filed: April 3, 2024
    Publication date: November 7, 2024
    Inventors: David Berman, Amar Bhatt, Antonio Ubach, Cara Lee Coad, Chasen Peters, Jeremiah Beers, Navid Mahpeykar, Patrick Digmann, Todd Baxendale
  • Publication number: 20240367961
    Abstract: A foldable rail assembly includes a lower rail assembly extending upwardly away from a platform, an upper rail assembly extending above the lower rail assembly, a rotatable member coupling the upper rail assembly to the lower rail assembly such that the upper rail assembly is movable between a first position and a second position, and a first latch and a second latch configured to limit movement of the upper rail assembly away from the second position when engaged. In the first position, the foldable rail assembly extends from the platform to a first height. In the second position, the foldable rail assembly extends from the platform to a second height, the first height being larger than the second height. The first latch engages in response to the upper rail assembly entering the second position. The second latch is manually engaged by an operator.
    Type: Application
    Filed: July 15, 2024
    Publication date: November 7, 2024
    Applicant: Oshkosh Corporation
    Inventors: Devin Rosencrance, David Hoover, Dorothy Greenberger
  • Publication number: 20240366885
    Abstract: Medication delivery methods, devices and systems are provided. The medication delivery device includes a retractable sheath mechanism connected to a distal end of the device. The retractable sheath mechanism is axially movable between a first position to cover a needle attached to the distal end and a second position to expose the needle with an adjustable protrusion length. The retractable sheath mechanism includes one or more skin sensors disposed on an end surface thereof to detect skin before and during injection. In some cases, a needle carousel is provided to connect to the distal end of the device. The needle carousel supports multiple needle capsules each including a needle.
    Type: Application
    Filed: May 3, 2024
    Publication date: November 7, 2024
    Inventors: Rachael Price, Matthew Clemente, Laurie Mendelson, Apurva Jadhav, Horst Pitchler, Amy Connell, Matthew Johnson, Namisha Lnu, Christina Bode, Ian Hanson, Aaron Morgan, Jane Zhang, Jenny Nguyen, Pawel Drozdz, Sarah Vaughan, Scott Telstad, Olga Smelyanets, Jorge A. Balderrama Canales, Janet Wu Chenie Chastain, Thomas Dean Jordan, Corydon A. Hinton, John Fresquez, David Lane, Chris Puryear, Peter Kimball, Vidya Saptharishi, Paul Pasika, Ashwin Sriram
  • Publication number: 20240372648
    Abstract: Scalable space-time quadrature spatial modulation for multidimensional wireless systems is performed by configuring a plurality of transmit antennas to each represent an in-phase spatial constellation symbol within an in-phase spatial constellation, and a quadrature spatial constellation symbol within a quadrature spatial constellation, mapping source data to the in-phase spatial constellation symbols and the quadrature spatial constellation symbols represented by the plurality of transmit antennas, wherein the method constructs the set which has equal multiplicities of the transmit antenna activation, which ensures maximum possible transmit diversity and reduces the required complexity, making this feasible for larger number of antennas.
    Type: Application
    Filed: July 25, 2022
    Publication date: November 7, 2024
    Applicant: Continental Automotive Technologies GmbH
    Inventors: David Gonzalez Gonzalez, Osvaldo Gonsa, Hiroki Iimori, Giuseppe Thadeu Freitas de Abreu, Hyeon Seok Rou
  • Publication number: 20240367200
    Abstract: The present application discloses a system, a method, and a computer system for correlating information to facilitate automated sortation. The method includes (i) receiving, by one or more processors, a first optical sensor data comprising a first element of routing data required to route an item but not a second element of routing data required, in addition to the first element, to route the item, (ii) obtaining the second element of routing data from a second optical sensor data, and (iii) causing the item to be routed based at least in part on the first element of routing data and the second element of routing data.
    Type: Application
    Filed: July 17, 2024
    Publication date: November 7, 2024
    Inventors: Timothy Ryan, David Leo Tondreau, III, Erik Trewitt
  • Publication number: 20240368634
    Abstract: The present disclosure provides for a method of purifying rubber from a plant that naturally produces rubber, the method including: a) contacting plant material with hot water or a dilute basic aqueous solution, thereby forming a plant material composition with a concentration of 3% or less of water extractable materials by weight and an inulin-containing composition; b) separating the plant material composition from the inulin-containing composition; c) pebble milling the plant material composition in the presence of enzymes; d) centrifuging the product of step c) to separate rubber from other material; and e) removing the rubber. Also provided herein is a product that can be obtained by any of the processes disclosed herein.
    Type: Application
    Filed: July 1, 2022
    Publication date: November 7, 2024
    Inventors: Frederick MICHEL, David Alexander RAMIREZ CADAVID
  • Publication number: 20240368398
    Abstract: The present invention relates to an injection moulded biodegradable component comprising: a) 60 to 99 wt % of a biodegradable film-grade bioplastic; and b) 0 to 40 wt % of filler comprising a biodegradable polymer and a non-toxic 5 mineral; and methods for producing said component.
    Type: Application
    Filed: July 28, 2022
    Publication date: November 7, 2024
    Inventors: David REARDON, Andrew George BOND
  • Publication number: 20240366829
    Abstract: A medical patch can comprise a biocompatible substrate and a dry hydrogel precursor layer on the substrate, the precursor layer comprising an electrophilic-hydrogel precursor having a plurality of electrophilic functional groups and a nucleophilic-hydrogel precursor having a plurality of protonated amine groups and no more than about 2 weight percent water. Both the electrophilic-hydrogel precursor and the nucleophilic-hydrogel precursor are substantially uncrosslinked, and are blended or in direct contact with each other. The medical patches can be formed by coating a melt blend of hydrogel precursors in a dry environment or based on solution coating from a dry, non-aqueous solvent, onto a porous, hydrophilic substrate, such as a compressed gelatin substrate. Flexible medical patches can be formed by methods that include compressing coated substrates, such as with calendering. The medical patches can be used for placement over a bleeding wound or the like and may function as a hemostatic patch.
    Type: Application
    Filed: May 3, 2023
    Publication date: November 7, 2024
    Inventors: Michael Bassett, Dan Thanh Le, David Giusti
  • Publication number: 20240370413
    Abstract: A labelled point within a multidimensional space is input from a set of input records. It is determined whether the labelled point is subsumed by a member hyperregion of the set of hyperregions specified by an BSRS, wherein the BSRS includes a boundary-structured rule corresponding to a hyperregion in the multidimensional space. In the event the labelled point is not subsumed, the BSRS is expanded or the labelled point is eliminated.
    Type: Application
    Filed: May 2, 2024
    Publication date: November 7, 2024
    Inventor: David R. Cheriton
  • Publication number: 20240371240
    Abstract: Methods and systems are disclosed to facilitate creating the sensation of vibrotactile movement on the body of a user. Vibratory motors are used to generate a haptic language for music or other stimuli that is integrated into wearable technology. The disclosed system in certain embodiments enables the creation of a family of devices that allow people such as those with hearing impairments to experience sounds such as music or other input to the system. For example, a “sound vest” or other wearable array transforms musical input to haptic signals so that users can experience their favorite music in a unique way, and can also recognize auditory or other cues in the user's real or virtual reality environment and convey this information to the user using haptic signals.
    Type: Application
    Filed: May 13, 2024
    Publication date: November 7, 2024
    Inventors: Mick Ebeling, Daniel Biscaro Loureiro, Patrick Hanlon, David Francis Putrino
  • Publication number: 20240370032
    Abstract: Substantially discontinuous surface feature traversal feature of the present teachings can leverage a transport device (TD), for example, but not limited to, an autonomous device or a semi-autonomous device, to navigate in environments that can include features such as substantially discontinuous surface features. The substantially discontinuous surface feature traversal feature can enable the TD to travel on an expanded variety of surfaces. In particular, substantially discontinuous surface features can be accurately identified and labeled so that the TD can automatically maintain the performance of the TD during ingress and egress of the substantially discontinuous surface feature.
    Type: Application
    Filed: July 19, 2024
    Publication date: November 7, 2024
    Inventors: Emily A. Carrigg, Patrick Steele, Gregory J. Buitkus, Benjamin V. Hersh, FNU G. Siva Perumal, David Carrigg, Kartik Khanna, Daniel F. Pawlowski, Arunabh Mishra, Yashovardhan Chaturvedi
  • Publication number: 20240368514
    Abstract: The invention is a cell culture container having a top, bottom and sidewalls defining an interior region and at least one cultivation vessel disposed within the container, the cultivation vessel has a generally frustoconical shape. A cover member is provided for closing the top of the container and sealing the at least one cultivation vessel. The cover member and the bottom of the container are adapted to interfit so that multiple cell culture containers may be stacked on top of each other.
    Type: Application
    Filed: May 2, 2024
    Publication date: November 7, 2024
    Inventor: Robert David Laidlaw
  • Publication number: 20240369828
    Abstract: An optical scanner includes a base region and a cantilevered silicon beam protruding from the base region. The optical scanner also includes a waveguide disposed on the base region and the cantilevered silicon beam and a transducer assembly comprising one or more piezoelectric actuators coupled to the cantilevered silicon beam and configured to induce motion of the cantilevered silicon beam in a scan pattern.
    Type: Application
    Filed: July 17, 2024
    Publication date: November 7, 2024
    Applicant: Magic Leap, Inc.
    Inventors: Charles David Melville, Steven Alexander-Boyd Hickman, Laura Cristina Trutoiu, Keith Lane Behrman
  • Publication number: 20240366275
    Abstract: A cerclage cable system is disclosed which includes a bone plate, one or more securing devices, and one or more cerclage cables. The bone plate includes a plurality of bone plate apertures thereupon, wherein the bone plate is configured to be affixed to a bone. The one or more securing devices include a body having a proximal end and a distal end, wherein at least one securing device aperture is disposed toward the proximal end, wherein the distal end of the securing device is configured to be inserted into and received by the plurality of bone plate apertures. The one or more cerclage cables include two terminal ends, wherein the one or more cerclage cables are wrapped around the bone, wherein one terminal end of the one or more cerclage cables is passed through at least one securing device aperture.
    Type: Application
    Filed: July 10, 2024
    Publication date: November 7, 2024
    Inventors: Zachary C. Shiner, David Machamer, Spiro Kokolis
  • Publication number: 20240373097
    Abstract: Methods, apparatus, systems, and articles of manufacture are disclosed to determine whether audience measurement meters are co-located. An example apparatus is to, based on a difference between a first sampling time of a first entry of a first log and a second sampling time of a corresponding entry of a second log satisfying a first threshold, determine at least one matching instance of at least one first device identifier of the first entry and at least one second device identifier of the corresponding entry. Additionally, the example apparatus is to populate a variable with the at least one matching instance. The example apparatus is also to, based on a metric satisfying a second threshold, cause transmission of an alert indicating that a first meter and a second meter were co-located during generation of the first log and the second log, the metric based on the at least one matching instance.
    Type: Application
    Filed: March 15, 2024
    Publication date: November 7, 2024
    Applicant: The Nielsen Company (US), LLC
    Inventors: Alexander Topchy, Ronny Lerch, John Stavropoulos, David Gish
  • Publication number: 20240368233
    Abstract: Polypeptides and fusion proteins capable of heterodimer formation, methods for their use, and methods for their design are provided.
    Type: Application
    Filed: July 11, 2022
    Publication date: November 7, 2024
    Inventors: David BAKER, Danny SAHTOE, Florian PRAETORIUS, Bart TIMMERMANS, Yang HSIA, Alexis COURBET, Natasha EDMAN