Abstract: Disclosed herein are methods and compositions for modulating expression of a PD1 gene.

Abstract: A downhole energy transmission system is described. The system can include a casing string having a number of casing pipe disposed within a wellbore, where the casing string has at least one wall forming a cavity. The system can also include a remote electrical device disposed within the cavity of the casing string at a first location. The system can further include a first stripline cable disposed on an outer surface of the casing string, where the first stripline cable transmits a first energy received from an energy source. The system can also include a second stripline cable disposed adjacent to the first stripline cable at the first location, where the second stripline cable is electrically coupled to the remote electrical device.

Abstract: A data file is encrypted with a file-specific encryption key and sent to a remote data storage system. The file-specific encryption key is encrypted with a master key. The encrypted file-specific encryption key and the master key are both stored remotely from the encrypted file and they are stored remotely from one another.

Abstract: A method and system for determining the presence or absence of a part of an assembly within at least one user-defined, 3-D detection region within a work cell are provided. The system includes a 3-D or depth sensor having a field of view at the work cell. The sensor has a set of radiation sensing elements which detect reflected, projected radiation to obtain 3-D sensor data. A processor processes the sensor data from the sensor to obtain a 3-D graphic of the at least one detection region. A display displays the 3-D graphic from a viewpoint to determine the presence or absence of the part within the detection region.

Abstract: An integrated slot waveguide antenna array for a radar system. The antenna array may include substrate integrated waveguide (SIW) elements, transmit, receive and processing electronics in a lightweight, low-cost, highly integrated package. The combination of antenna layout, specific dimensions of SIW features, including vias, terminal edges and slot placement may allow an efficient transmit and receive radar pattern as well as consistent, reliable and low cost manufacturing.

Abstract: A camming member for a door may have a camming surface which lifts the door as the door is traversed from an opened position to a closed position. The lifting movement of the door caused by the camming member facilitates one or more latches used to reinforce a periphery of the door to be engaged without further user intervention.

Abstract: The invention features a refrigerator cabinet door frame. The frame includes a thermally conductive outer frame, a thermally insulating inner frame member, and a sealing plate. The outer frame member includes a forward end having an outer surface that is disposed outside of a refrigerated cabinet with the frame mounted, and a rearward end defining a joint. The inner frame member includes a first end retained in the joint, and a second end. The sealing plate includes a first edge coupled to the outer frame member at the rearward end, forward of the joint, a second edge supported by the second end of the inner frame member, and a thermally conductive sealing surface. The first edge of the sealing plate is coupled to the outer frame member such that the sealing surface and the outer surface of the outer frame member together form a continuous heat transfer path.

Abstract: Provision of inorganic powders with reduced hazard: acid chlorides which have use in polymer production can be incorporated into a masterbatch with the addition of a silane compound to reduce the corrosiveness of the masterbatch pellets and reduce variability of pellet size. This presents advantages in transport and handling costs and facilitates downstream processing.

Abstract: An apparatus for storing and retrieving electronic components such as, but not limited to: capacitors; resistors; and integrated circuits. Components are stored based on single package single location in lockable racks in a transportable cart. Information for each stored component, such as its part number, location, and quantity is stored in the local electronic board and is shared via Wi-Fi to a network of PCs.

Abstract: Techniques for dynamic network optimization using geolocation and network modeling are disclosed. In one particular exemplary embodiment, the techniques may be realized as a system for network optimization. The system may comprise a data collection system configured to collect geolocated subscriber records from a plurality of mobile devices. The system may also comprise a SON optimization system communicatively coupled to the data collection system via a network. The SON optimization system may comprise at least one pre-processor configured to receive and process geolocated subscriber records from the data collection system. The SON optimization system may further comprise a network simulator configured to perform network simulation analysis based on the processed geolocated subscriber records, and provide a new network configuration based on the network simulation analysis, wherein the new network configuration is estimated to improve network performance.

Abstract: New compositions for and methods of treating ocular hypertension provide for effective treatment of ocular hypertension often using reduced concentrations of active components. Such compositions include a timolol component and a hypotensive lipid component. The present compositions and methods are relatively straightforward, can be easily produced, for example, using conventional manufacturing techniques, and can be easily and conveniently practiced, for example, using application or administration techniques or methodologies which are substantially similar to those employed with prior compositions used to treat ocular hypertension.

Abstract: An automatic injector includes a housing having a guide, a drive control mechanism, a transmission assembly, a motor, and an energy source. The housing may further include a cartridge cover. A drive control mechanism includes a drive screw, a cartridge carrier, a plunger carrier, and one or more control transfer instruments, such as a puck or cylinder. The drive screw interfaces and connects with the plunger carrier. The automatic injector is configured to accept a variety of syringes as cartridges for drug delivery. The cartridges may be ejected from the injector and safely disposed after use, making the injector a reusable automatic injector. The reusable automatic injector may further include one or more sensors, such as a cartridge sensor and a patient sensor.

Abstract: A compressor for a gas turbine engine including one or more endwall treatments for controlling leakage flow and circumferential flow non-uniformities in the compressor. The compressor includes a casing, a hub, a flow path formed between the casing and the hub, a plurality of blades positioned in the flow path, and one or more circumferentially varying end-wall treatments formed in an interior surface of at least one of the casing or the hub. Each of the one or more circumferentially varying endwall treatments circumferentially varying based on their relative position to an immediately adjacent upstream bladerow. Each of the one or more endwall treatments is circumferentially varied in at least one of placement relative to the immediately adjacent upstream bladerow or in geometric parameters defining each of the plurality of circumferentially varying endwall treatments. Additionally disclosed is an engine including the compressor.

Abstract: A pickup truck having a tonneau cover is provided. The tonneau cover includes a first panel section pivotable with respect to the opposing first and second upward-extending side walls. A first latching assembly is attached to the first panel section and is configured to selectively secure and release the first panel section with respect to the first and second side walls of the pickup truck. The first latching assembly includes first and second pinch latch assemblies. The first pinch latch assembly is located adjacent the first upward-extending side wall of the pickup truck and the second pinch latch assembly is located adjacent the second upward-extending side wall of the pickup truck.

Abstract: A method of outputting audio in a teleconferencing environment includes receiving audio streams, processing the audio streams according to information regarding effective spatial positions, and outputting, by at least three speakers arranged in more than one dimension, the audio streams having been processed. The information regarding the plurality of effective spatial positions corresponds to a perceived spatial scene that extends beyond the speakers in at least two dimensions. In this manner, participants in the teleconference perceive the audio from the remote participants as originating at different positions in the teleconference room.

Abstract: An apparatus for implementing an enhanced-write-bandwidth caching stream includes a memory that stores machine instructions and a processor that executes the machine instructions. The apparatus receives a first host write stream and a second host write stream that comprises latency-sensitive host write requests. The apparatus also subjects the first host write stream to host-write throttling, and exempts the second host write stream from host-write throttling. The apparatus further requires that the second host write stream invalidate logical blocks in an order corresponding to a previous order in which the respective logical blocks were previously programmed.

Abstract: A system and method of managing equipment is disclosed. The system incorporates a tagging device to attach identification tags to each piece of equipment. A scanning device is used to read the identification tags and relay this information to an equipment server. An input device is used to input information to the equipment server. The equipment server runs the equipment management program. The system flags a potential asset assigned to an asset creating individual. Equipment is designated an asset after use in an asset creating event.

Abstract: Disclosed aspects include management of a set of blocks in a storage system. A set of write requests is initiated to the set of blocks. In response to the set of write requests, a set of expiration metadata for the set of blocks is established. Based on the set of expiration metadata, an expiration event is detected. In response to detecting the expiration event, an expiration operation on the set of blocks is processed.