Abstract: A process for preparing a thermoplastic copolyester which comprises repeating units derived from an aliphatic glycol, an aromatic dicarboxylic acid, and the monomer of formula (I): wherein n=2, 3 or 4, and wherein comonomer (I) constitutes a proportion of the glycol fraction of the copolyester, wherein the process comprises the steps of: (i) reacting said aliphatic glycol with said aromatic dicarboxylic acid to form a bis(hydroxyalkyl)-ester of said aromatic dicarboxylic acid; and (ii) reacting said bis(hydroxyalkyl)-ester of said aromatic dicarboxylic acid with the monomer (I) under conditions of elevated temperature and pressure in the presence of a catalyst, wherein the monomer (I) is present in a range of from 5% to about 20 mol % of the glycol fraction of the copolyester, wherein the aromatic dicarboxylic acid is selected from naphthalene dicarboxylic acid and terephthalic acid, and wherein the aliphatic glycol is ethylene glycol.

Abstract: Techniques are described for reducing time to decrypt a next encrypted frame in a content stream by optimizing a license/key acquisition process. When requesting content, a key identifier and/or license identifier may be included within a webpage using a link, script, or similar access point. When a client device sends a request for content, the loading of the webpage within the client device includes the embedded key identifier. Access to the key/license identifier at the client device then may initiate a key/license acquisition process by the client device. The key/license may be obtained from a key management device in parallel with, or prior to, downloading of at least a portion of the content stream.

Abstract: Methods and compositions are provided for determining whether an adenocarcinoma or squamous cell carcinoma patient is likely to respond to PARP inhibitor treatment. Specifically, a method of assessing whether a patient's adenocarcinoma (AD) lung cancer subtype is terminal respiratory unit (TRU), proximal inflammatory (PI), or proximal proliferative (PP) or a patient's squamous cell carcinoma (SQ) is primitive, classical, secretory or basal is provided herein. The method entails detecting the levels of classifier biomarkers at the nucleic acid level, in an AD or SQ lung cancer sample obtained from the patient. Based in part on the levels of the classifier biomarkers, the AD lung cancer sample is classified as a TRU, PI, or PP AD sample or the SQ lung cancer sample is classified as primitive, classical, secretory or basal and a determination of whether the patient is likely to respond to PARP inhibitor treatment can be made.

Abstract: Reconfigurable computing clusters, compute nodes within reconfigurable computing clusters, and methods of operating a reconfigurable computing cluster are disclosed. A reconfigurable computing cluster includes an optical circuit switch, and a plurality of computing assets, each of the plurality of computing assets connected to the optical circuit switch by two or more bidirectional fiber optic communications paths.

Abstract: A system and process to estimate persuasiveness of public messaging using surveys are disclosed. According to one embodiment, a method comprises selecting survey participants. Pre-screening question responses are received from the survey participants. The survey participants are divided randomly into a control group and a treatment group. The treatment group is shown a creative and a control group is shown nothing or a placebo. After the creative has been shown, participants are asked post-message questions such as purchase intent, favorability of the brand, and brand awareness. Weighting and bias correction are applied to question responses. An effects report is generated that includes an average treatment effect and a backlash probability for the creative, and treatment effects specific to subgroups.

Abstract: A graphical user interface for displaying an electronic medical record associated with a patient is provided. The graphical user interface may include an area configured to display patient information, which may include at least a name of the patient. The graphical user interface may also include an indicator displayed in association with the name of the patient. The indicator may include information specifying that the patient is potentially eligible for one or more trials, the patient is participating in one or more trials, or the patient has completed one or more trials.

Abstract: Systems and methods for automatically generating a boot sequence. A multiple virtual machine computing environment is analyzed to generate a boot sequence that is used during a recovery operation. The boot sequence may be based on applications and application types running on the virtual machines, a network configuration and network traffic, and on manual boots of virtual machines. The boot sequence prioritizes the order in which the virtual machines are booted in the recovery site.

Abstract: A flip-flop circuit includes two inverters and two transmission circuits. The two inverters and the two transmission circuits are implemented using reverse direction high-electron-mobility transistors.

Abstract: Devices, systems, and methods are disclosed for cooling using both air and/or liquid cooling sub circuits. A vapor compression cooling system having both an air and liquid cooling sub circuit designed to service high sensible process heat loads that cannot be solely cooled by either liquid or air is provided.

Abstract: Described herein is the Bruton's tyrosine kinase (Btk) inhibitor 1-((R)-3-(4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)prop-2-en-1-one, including crystalline forms, solvates and pharmaceutically acceptable salts thereof. Also disclosed are pharmaceutical compositions that include the Btk inhibitor, as well as methods of using the Btk inhibitor, alone or in combination with other therapeutic agents, for the treatment of autoimmune diseases or conditions, heteroimmune diseases or conditions, cancer, including lymphoma, and inflammatory diseases or conditions.

Abstract: An apparatus and method for simultaneously testing a plurality of mobile devices is disclosed. The method for simultaneously testing a plurality of mobile devices generally includes simultaneously executing a test mobile device application on the plurality of mobile devices, determining test mobile device application results for the plurality of mobile devices at a plurality of test computers, sending a test mobile device application results from the plurality of mobile devices to the plurality of test computers, and deleting the test mobile device application on the plurality of mobile devices.

Abstract: A holding apparatus, which is adapted for electrostatically holding a component, in particular a wafer, comprises an electrically insulating base body, which comprises a first pair of base body plates, which are connected to one another in a planar manner via a joint connection, and an electrode device with at least one electrode layer, which is arranged to generate an electrostatic holding force and extends parallel to the extension of the base body plates along the joining connection, wherein the joining connection comprises a diffusion bond connection, wherein the at least one electrode layer is connected in a planar manner to the respectively adjacent base body plate, and the at least one electrode layer has a contact section, which is arranged for electrically contacting the at least one electrode layer. Methods for manufacturing the holding apparatus are also described.

Abstract: A computer-implemented method, a system and a computer program product for processing third party online coupons. According to one embodiment, a third-party online coupon is received. Text is parsed to determine a merchant's website. The third-party online coupon description is parsed to determine a product term. The product term is searched for. The third-party online coupon is tested with a product associated with the product term. The third-party online coupon is determined if valid with the product.

Abstract: This invention relates to compounds of the general formula: in which the variable groups are as defined herein, and to their preparation and use.

Abstract: A flap (20) for an inhalation actuated mechanism (18) of a powder inhaler (1) comprises a base member (29), a skirt structure (24) projecting from a surface of the base member (29), and a coupling portion (21) to be coupled to a resilient member (40?) of the inhalation actuated mechanism (18).

Abstract: A chalk-holder for billiard-cues system including a chalk holder having a receptacle including an inner volume and a securing member. The inner volume is configured to store chalk for removeable use. The securing member is configured to engage and be secured at a handle-end of a pool cue for providing ready access to the chalk. The securing member comprises threading. The handle-end comprises an aperture configured to mate with the threading of the securing member. The device may be used to store chalk between uses during billiards.

Abstract: An optical lens having three discrete filtering zones is disclosed for eyeglasses. The eyeglasses can be worn two to four hours prior to bedtime to reestablish a proper circadian rhythm even in the presence of artificial evening light. The three discrete filtering zones can differently filter green or blue light.

Abstract: A securing system for securing an electric bicycle to a bicycle docking frame includes a female connecting assembly mountable on the bicycle docking frame and a male connecting assembly mountable on the electric bicycle and sized to be received within a tapered recess of the female connecting assembly. When so received, first current coupling elements of the female assembly electrically interface with second current coupling elements of the male assembly, which can allow current flow therebetween to charge a battery of the electric bicycle. A bicycle rack system includes electric bicycles, bicycle docks, a charging module operable to receive electrical power from an external power source and a charging controller for adjusting the level of electrical power provided to dock-side charging modules that charge battery modules of electric bicycles docked thereto. A method for managing charging is also provided.

Abstract: The technology relates in part to methods for inducing partial apoptosis of cells that express an inducible caspase polypeptide. The technology further relates in part to methods for inducing partial apoptosis of cells that express an inducible modified caspase polypeptide, having a modified dose response curve to the multimeric ligand inducer. The technology also relates in part to methods for cell therapy using cells that express the inducible caspase polypeptide or the inducible modified caspase polypeptide, where the proportion of caspase polypeptide-expressing cells eliminated by apoptosis is related to the administered amount of the multimeric ligand inducer.

Abstract: Design tools and methods of use for designing, ordering, and providing manufacturing and installation instructions for waveguide system networks include a system design tool including a location selection module to determine a selected location, a satellite imagery component to provide an image based on the selected location, an overlay module to overlay a design on the image, and a customization module to customize the design. The system design tool includes one or more design modules to at least one of automatically output and build via user input one or more design options based on the image, and a design customization module to select the design from the one or more design options. The system design tool includes a positioning module to set a pair of connectivity points such that a cable length may be automatically calculated based on a calculated distance between the pair of connectivity points.