Abstract: An apparatus and method are disclosed for the automated manufacture of a duct flange profile to make small duct fittings, including a transverse duct flange duct flange profile. The duct flange profile is directed to small part duct fittings with section widths up to about 16 inches in 20 to 26 gauge metal. The apparatus includes a bending head assembly having a drive roller, a pressure roller, an anvil and a bending leaf and a roll form assembly.

Abstract: A system and methods comprise a touchscreen at a premises. The touchscreen includes a processor coupled to a security system at the premises. User interfaces are presented via the touchscreen. The user interfaces include a security interface that provides control of functions of the security system and access to data collected by the security system, and a network interface that provides access to network devices. A camera at the premises is coupled to the touchscreen via a plurality of interfaces. A security server at a remote location is coupled to the touchscreen via a plurality of channels and a plurality of protocols. The security server comprises a client interface through which remote client devices exchange data with the touchscreen and the security system.

Abstract: The present disclosure provides antibodies, including antibody fusions, which specifically bind to human CSF1 receptor protein (huCSF1R) and are capable of decreasing, inhibiting, and/or fully-blocking immune regulatory effects mediated by huCSF1R, such as regulation of TAMs in the tumor microenvironment. Additionally, the antibodies include fusions with the cytokine inhibitory factor, IL10, which can replenish and/or activate CD8+T-cell cytotoxicity in the tumor microenvironment. The present disclosure also provides methods of using the antibodies (and compositions thereof) to treat diseases and conditions responsive to decreasing, inhibiting and/or blocking immune regulatory function or activity mediated by CSF1 binding to CSF1R.

Abstract: A multi-core thermocouple includes a plurality of wires, an insulation core surrounding the plurality of wires, a sheath surrounding the insulation core, and a plurality of electrical junctions. The plurality of electrical junctions may include a first electrical junction formed between a first wire of the plurality of wires and the sheath at a first axial mid-section of the multi-core thermocouple, the first electrical junction including a first swaged axial mid-section of the sheath and a second electrical junction formed between a second wire of the plurality of wires and the sheath at a second, different axial mid-section of the multi-core thermocouple, the second electrical junction including a second swaged axial mid-section of the sheath.

Abstract: A security system is described for managing a premises. The security system comprises security system components and a first controller. A takeover component receives security data of the security system from the first controller. The security data is used to configure a second controller to communicate with the security system. The second controller communicates with the security system components and replaces the first controller in management of the security system.

Abstract: A system and methods comprise a touchscreen at a premises. The touchscreen includes a processor coupled to a security system at the premises. User interfaces are presented via the touchscreen. The user interfaces include a security interface that provides control of functions of the security system and access to data collected by the security system, and a network interface that provides access to network devices. A camera at the premises is coupled to the touchscreen via a plurality of interfaces. A security server at a remote location is coupled to the touchscreen via a plurality of channels and a plurality of protocols. The channels include a short message service (SMS) channel, a remote control channel, and an asynchronous event channel. The security server comprises a client interface through which remote client devices exchange data with the touchscreen and the security system.

Abstract: An apparatus for use with a robotic high throughput sample preparation machine. The apparatus includes: a tool retaining portion configured to engage and disengage with a sample preparation tool, and a rotation element configured to rotate the engagement portion. Actuation of the rotation element causes the tool retaining portion to alternately engage and disengage a sample preparation tool. The tool retaining portion may be configured to engage multiple sample preparation tool types such as syringes, needles, and media-containing cartridges such as those used for solid phase extraction.

Abstract: A sensor for passively measuring a maximum temperature within a nuclear reactor comprises a substrate, and a plurality of melt wires within a cavity defined within the substrate, at least one melt wire of the plurality of melt wires exhibiting a variable melting temperature along a length of the at least one melt wire. Related sensors and methods of forming the sensors are also disclosed.

Abstract: Systems and methods are disclosed herein for generating for display a notification to a plurality of users at a position within a display screen to which each user of the plurality of users is paying attention. Specifically, the media guidance application captures lines of sight of users who are paying attention to a display screen, based on which the media guidance application determines line-of-sight regions on the display screen that the users are paying attention to. The media guidance application then determines a display area that is noticeable to the users based on the respective line-of-sight regions on the display screen to display an electronic message.

Abstract: An autonomous cargo handling system having a sensor self-calibration system may comprise a sensing agent configured to monitor a sensing zone, and a system controller in electronic communication with the first sensing agent. The system controller may be configured to receive structural cargo deck data from the first sensing agent, generate a real-time cargo deck model, identify a cargo deck component in the real-time cargo deck model, and determine a position of the sensing agent relative to the cargo deck component.

Abstract: Methods and systems for managing a security system are described. A security server located external to a premises may be in communication with a security system and a gateway device located at the premises. A status signal may be sent to the security server. The status signal may be initiated based on an alarm event. If the security server fails to detect a message of the status signal, the security server may send one or messages indicating the failure.

Abstract: Preparation of halogen-doped silica is described. The preparation includes doping silica with high halogen concentration and sintering halogen-doped silica to a closed-pore state in a gas-phase environment that has a low partial pressure of impermeable gases. Impermeable gases are difficult to remove from halogen-doped fiber preforms and lead to defects in optical fibers drawn from the preforms. A low partial pressure of impermeable gases in the sintering environment leads to a low concentration of impermeable gases and a low density of gas-phase voids in densified halogen-doped silica. Preforms with fewer defects result.

Abstract: Systems and methods are provided for event-based route planning. Information of events taking place in a predetermined geographic area is received. An origin and at least one destination are determined. One or more first routes for traveling from the origin to the destination are determined from the predetermined geographic area. One or more segments in each of the first routes are determined based on the received information, each segment being associated with a corresponding recommendation for travelling via the segment.

Abstract: The invention relates to a novel process for preparing a-carboxamide pyrrolidine derivatives, in particular (2S, 5R)-5-(4-((2-fluorobenzyl)oxy)phenyl)pyrrolidine-2-carboxamide, and to novel intermediates for use in said process along with processes for preparing said intermediates.

Abstract: Methods, systems, and apparatus for authenticating and authorizing users using quantum key distribution through segmented quantum computing environments. In one aspect, a method includes receiving a first and second plaintext data input from a first party and from a second party, respectively; applying a quantum computation translation operation to the first and second plaintext data inputs to generate a corresponding first sequence of quantum computations and a second sequence of quantum computations; implementing the first and second sequence of quantum computations in a first and second segmented quantum computing environment, respectively, to obtain a first and second sequence of measurement results; generating a first and second encryption key using the first and second sequence of measurement results, respectively, and an encrypted authorization token using the second encryption key; and sending the first encryption key to the first party, and the encrypted authorization token to the second party.

Abstract: Methods, apparatus, and processor-readable storage media for automated alert augmentation for deployments of software-defined storage are provided herein. An example computer-implemented method includes obtaining an alert from at least one software-defined storage device; determining one or more items of additional information pertaining to one or more of the alert and the at least one software-defined storage device; augmenting the alert based at least in part on the one or more determined items of additional information; generating a modified version of the augmented alert by incorporating, into the augmented alert, dependency information pertaining to the at least one software-defined storage device and one or more additional software-defined storage devices; and performing one or more automated actions based at least in part on the modified version of the augmented alert.

Abstract: Methods, systems, and apparatus, including computer programs encoded on computer storage media, for authenticating users based on a sequence of biometric authentication challenges. In one aspect, a process includes receiving a first image of the face of the user and processing the first image according to a first authentication process to determine whether the face of the user shown in the first image matches the face of an authorized user. A second authentication process including a sequence of biometric authentication challenges is identified. The sequence includes at least one facial expression challenge. The user is authenticated in response to determining that the first authentication process is satisfied based on the face of the user shown in the first image matching the face of the authorized user and the second authentication process is satisfied based on the user providing a valid biometric response to each biometric authentication challenge.

Abstract: Disclosed are methods, systems, and devices for management of a premises. The premises may comprise one or more devices, such as a gateway device, a control device, or a premises device. The gateway device may receive data and send the data to the control device. The data may comprise a command, an update, a configuration, or other information. Communication between the control device and any of the other devices at the premises may be configurable by a server device.

Abstract: Methods and systems for managing a premises are disclosed. An interface device and a premises system may be located at the premises. The interface device may receive a signal from a premises device of the premises system. An indication of the premises device may be output via a user interface. Configuration information may be associated with the premises device. The interface may monitor and control the premises device.

Abstract: Systems, apparatuses, and methods are described for managing and synchronizing viewing progress of a content item by multiple users. In one implementation, a user returning to a joint viewing session may be presented with options for catching up to other users in the joint viewing session, or otherwise see what the returning user previously missed.