Patents by Inventor Dayong Gao

Dayong Gao has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20030097845
    Abstract: A heating and cooling apparatus to be applied to an object to control the temperature of the object. A number of thermoelectric modules are adapted to be positioned in contact with the object in a pattern. A voltage source is adapted to apply a voltage to the thermoelectric modules to cause a temperature change in each thermoelectric module so as to control the temperature of the object in accordance with the pattern and with the voltage applied to thermoelectric modules.
    Type: Application
    Filed: July 2, 2002
    Publication date: May 29, 2003
    Inventors: John Saunders, Jamey D. Jacob, Dayong Gao, Michel A. Myers
  • Patent number: 6054287
    Abstract: A mathematical model, the membranes and devices based upon that model to optimize protocols for the addition or removal of cryoprotectant to or from biological cells, and a method to observe the biological cells and obtain the data to implement the models. This disclosure describes the use of four equations to predict optimal protocols to add or remove cryoprotectant to or from biological cells. The equations particularly require experimentally found data, specific to cell-type and species, regarding the osmotic tolerance of the cells, where osmotic tolerance refers to the cells ability to shrink or swell to various changes in osmolality without injury. The equations further require the cryoprotectant permeability coefficient and the water permeability coefficient of the particular cells' plasma membrane.
    Type: Grant
    Filed: February 27, 1998
    Date of Patent: April 25, 2000
    Assignee: Methodist Hospital of Indiana, Inc.
    Inventors: Dayong Gao, John K. Critser
  • Patent number: 5753427
    Abstract: A mathematical model, and membranes and devices based upon that model, to optimize protocols for the addition or removal of cryoprotectant to or from biological cells. This disclosure describes the use of four equations to predict optimal protocols to add or remove cryoprotectant to or from biological cells. The equations particularly require experimentally found data, specific to cell-type and species, regarding the osmotic tolerance of the cells, where osmotic tolerance refers to the cells ability to shrink or swell to various changes in osmolality without injury. The equations further require the cryoprotectant permeability coefficient and the water permeability coefficient of the particular cells' plasma membrane. These coefficients are found with experimental data of the knetic volume change of the cell-type to a known concentration and temperature of cryoprotectant.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: May 19, 1998
    Assignee: Methodist Hospital of Indiana
    Inventors: John K. Critser, Dayong Gao
  • Patent number: 5611787
    Abstract: The present invention provides a method and device for placement of a gastric line in the digestive tract of a patient. A guide element is either formed integrally with the end of a gastric line or it is formed separately to be fixed on the end segment of a gastric line to reduce the flexibility of the gastric line segment and facilitate the positioning of the gastric line in a patient's digestive tract. The guide element is provided with means for slideably engaging a previously positioned transepiglottal guide line so that the guide element when engaged with the guide line, can be pushed down the guide line to position the gastric line in an esophageal or post-esophageal position. An optional mouthpiece is provided to receive and guide the gastric tube toward the middle of the posterior oral pharynx during insertion and to protect the gastric line from the biting surfaces of the teeth and maintain its position in the mouth after insertion.
    Type: Grant
    Filed: October 13, 1994
    Date of Patent: March 18, 1997
    Assignee: Methodist Hospital of Indiana, Inc.
    Inventors: Robert J. Demeter, Henry C. Bock, Dayong Gao
  • Patent number: 5595866
    Abstract: A mathematical model to optimize protocols for the addition or removal of cryoprotectant to or from sperm cells. This disclosure describes the use of four equations to predict optimal protocols to add or remove cryoprotectant to or from sperm cells. The equations particularly require experimentally found data, specific to a species of sperm, regarding the osmotic tolerance of sperm cells, where osmotic tolerance refers to the sperm cells ability to shrink or swell to various changes in osmolality without injury. The equations further require the cryoprotectant permeability coefficient and the water permeability coefficient of the particular sperm cells' plasma membrane. Also disclosed are two particularly preferred methods to add or remove cryoprotectant to or from sperm. These preferred methods are Fixed-Volume-Step addition/removal of cryoprotectant or Fixed-Molarity-Step addition/removal of cryoprotectant.
    Type: Grant
    Filed: May 27, 1994
    Date of Patent: January 21, 1997
    Assignee: Methodist Hospital of Indiana, Inc.
    Inventors: John K. Critser, Dayong Gao