Patents by Inventor Dean Artis

Dean Artis has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Molecular scaffolds for kinase ligand development
    Publication number: 20050164300
    Abstract: Molecular scaffolds for compounds active on protein kinases are described, along with methods for using such scaffolds for kinase ligand development. The use of kinase structural information, exemplified with PIM-1 crystals and structural information can, for example, be used for identifying molecular scaffolds and for developing ligands that bind to and modulate particular kinases.
    Type: Application
    Filed: September 15, 2004
    Publication date: July 28, 2005
    Inventors: Dean Artis, Ryan Bremer, Samuel Gillette, Clarence Hurt, Prabha Ibrahim, Rebecca Zuckerman
  • Ligand development using PDE4B crystal structures
    Publication number: 20050079548
    Abstract: The use of PDE4B crystals and strucural information for identifying molecular scaffolds and for developing ligands that bind to and modulate PDE4B is described.
    Type: Application
    Filed: July 7, 2004
    Publication date: April 14, 2005
    Inventors: Dean Artis, Gideon Bollag, Graeme Card, Fernando Martin, Michael Milburn, Kam Zhang
  • PDE5A crystal structure and uses
    Publication number: 20050048573
    Abstract: A crystal structure of PDE5A is described that was determined by X-ray crystallography. The use of PDE5A crystals and strucural information can, for example, be used for identifying molecular scaffolds and for developing ligands that bind to and modulate PDE5A.
    Type: Application
    Filed: February 3, 2004
    Publication date: March 3, 2005
    Inventors: Dean Artis, Gideon Bollag, Graeme Card, Fernando Martin, Michael Milburn, Kam Zhang
  • PPAR active compounds
    Publication number: 20050038246
    Abstract: Compounds are described that are active on PPARs, including pan-active compounds. Also described are methods for developing or identifying compounds having a desired selectivity profile.
    Type: Application
    Filed: July 16, 2004
    Publication date: February 17, 2005
    Inventors: James Arnold, Dean Artis, Clarence Hurt, Prabha Ibrahim, Heike Krupka, Jack Lin, Michael Milburn, Weiru Wang, Chao Zhang