Patents by Inventor Deborah Lynn Greene NGUYEN

Deborah Lynn Greene NGUYEN has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Engineered renal tissues, arrays thereof, and methods of making the same
    Patent number: 10094821
    Abstract: Disclosed are renal tissues and arrays thereof that include a layer of renal interstitial tissue, the renal interstitial tissue comprising renal fibroblasts and endothelial cells; and a layer of renal epithelial tissue, the renal epithelial tissue comprising renal tubular epithelial cells, the renal epithelial tissue in contact with the layer of renal interstitial tissue to form a three-dimensional, engineered, biological renal tissue. Also disclosed are methods of fabricating and using the same.
    Type: Grant
    Filed: September 8, 2016
    Date of Patent: October 9, 2018
    Assignee: Organovo, Inc.
    Inventors: Deborah Lynn Greene Nguyen, Shelby Marie King, Sharon C. Presnell
  • Engineered Three-Dimensional Skin Tissues, Arrays Thereof, and Methods of Making the Same
    Publication number: 20180272035
    Abstract: Disclosed are bioprinted, three-dimensional, biological skin tissues comprising: a dermal layer comprising dermal fibroblasts; and an epidermal layer comprising keratinocytes, the epidermal layer in contact with the dermal layer to form the three-dimensional, engineered, biological skin tissue. Also disclosed are arrays of engineered skin tissues and methods of making engineered skin tissues.
    Type: Application
    Filed: November 5, 2015
    Publication date: September 27, 2018
    Inventors: Kelsey Nicole Retting, Colin M. O'Neill, Deborah Lynn Greene Nguyen, Sharon C. Presnell, Jessica Langer, Guive Balooch, Elizabeth Wu, Julien Demaude
  • Improved Methods for Tissue Fabrication
    Publication number: 20180265839
    Abstract: Disclosed herein are improved methods for fabricating bioprinted, three-dimensional, biological tissues. The methods relate to exposures to low temperatures, incubations at low temperatures of various durations, and fabrication in environments without structural cross-linking treatments.
    Type: Application
    Filed: November 9, 2016
    Publication date: September 20, 2018
    Inventors: Kelsey Nicole RETTING, Deborah Lynn Greene NGUYEN, Sharon C. PRESNELL, Shelby Marie KING
  • Engineered Three-Dimensional Breast Tissue, Adipose Tissue, and Tumor Disease Model
    Publication number: 20180196034
    Abstract: Described are three-dimensional, engineered, biological breast tissues, adipose tissues, and tumor models, including breast cancer models.
    Type: Application
    Filed: March 5, 2018
    Publication date: July 12, 2018
    Inventors: Shelby Marie KING, Deborah Lynn Greene Nguyen, Vivian A. Gorgen, Benjamin R. Shepherd, Sharon C. Presnell, Rosalie Sears, Brittany Allen-Petersen, Ellen Langer
  • Engineered three-dimensional breast tissue, adipose tissue, and tumor disease model
    Patent number: 9983195
    Abstract: Described are three-dimensional, engineered, biological breast tissues, adipose tissues, and tumor models, including breast cancer models.
    Type: Grant
    Filed: April 3, 2015
    Date of Patent: May 29, 2018
    Assignee: Organovo, Inc.
    Inventors: Shelby Marie King, Deborah Lynn Greene Nguyen, Vivian A. Gorgen, Benjamin R. Shepherd, Sharon C. Presnell
  • METHODS FOR TISSUE FABRICATION
    Publication number: 20170130192
    Abstract: Disclosed herein are improved methods for fabricating bioprinted, three-dimensional, biological tissues. The methods relate to exposures to low temperatures, incubations at low temperatures of various durations, and fabrication in environments without structural cross-linking treatments.
    Type: Application
    Filed: November 9, 2015
    Publication date: May 11, 2017
    Inventors: Kelsey Nicole RETTING, Deborah Lynn Greene NGUYEN, Sharon C. PRESNELL, Shelby Marie KING
  • Engineered Renal Tissues, Arrays Thereof, and Methods of Making The Same
    Publication number: 20170131264
    Abstract: Disclosed are renal tissues and arrays thereof that include a layer of renal interstitial tissue, the renal interstitial tissue comprising renal fibroblasts and endothelial cells; and a layer of renal epithelial tissue, the renal epithelial tissue comprising renal tubular epithelial cells, the renal epithelial tissue in contact with the layer of renal interstitial tissue to form a three-dimensional, engineered, biological renal tissue. Also disclosed are methods of fabricating and using the same.
    Type: Application
    Filed: September 8, 2016
    Publication date: May 11, 2017
    Inventors: Deborah Lynn Greene NGUYEN, Shelby Marie KING, Sharon C. PRESNELL
  • ENGINEERED THREE-DIMENSIONAL BREAST TISSUE, ADIPOSE TISSUE, AND TUMOR DISEASE MODEL
    Publication number: 20170023550
    Abstract: Described are three-dimensional, engineered, biological breast tissues, adipose tissues, and tumor models, including breast cancer models.
    Type: Application
    Filed: June 6, 2014
    Publication date: January 26, 2017
    Inventors: Shelby Marie King, Deborah Lynn Greene Nguyen, Vivian A. Gorgen, Benjamin R. Shepherd, Sharon c. Presnell, Rosalie Sears, Brittany Allen-Petersen, Ellen Langer
  • Engineered renal tissues, arrays thereof, and methods of making the same
    Patent number: 9481868
    Abstract: Disclosed are renal tissues and arrays thereof that include a layer of renal interstitial tissue, the renal interstitial tissue comprising renal fibroblasts and endothelial cells; and a layer of renal epithelial tissue, the renal epithelial tissue comprising renal tubular epithelial cells, the renal epithelial tissue in contact with the layer of renal interstitial tissue to form a three-dimensional, engineered, biological renal tissue. Also disclosed are methods of fabricating and using the same.
    Type: Grant
    Filed: October 6, 2015
    Date of Patent: November 1, 2016
    Assignee: Organovo, Inc.
    Inventors: Deborah Lynn Greene Nguyen, Shelby Marie King, Sharon C. Presnell
  • ENGINEERED THREE-DIMENSIONAL SKIN TISSUES, ARRAYS THEREOF, AND METHODS OF MAKING THE SAME
    Publication number: 20160122723
    Abstract: Disclosed are bioprinted, three-dimensional, biological skin tissues comprising: a dermal layer comprising dermal fibroblasts; and an epidermal layer comprising keratinocytes, the epidermal layer in contact with the dermal layer to form the three-dimensional, engineered, biological skin tissue. Also disclosed are arrays of engineered skin tissues and methods of making engineered skin tissues.
    Type: Application
    Filed: November 5, 2015
    Publication date: May 5, 2016
    Inventors: Kelsey Nicole RETTING, Colin M. O'Neill, Deborah Lynn Greene NGUYEN, Sharon C. PRESNELL
  • ENGINEERED RENAL TISSUES, ARRAYS THEREOF, AND METHODS OF MAKING THE SAME
    Publication number: 20160097039
    Abstract: Disclosed are renal tissues and arrays thereof that include a layer of renal interstitial tissue, the renal interstitial tissue comprising renal fibroblasts and endothelial cells; and a layer of renal epithelial tissue, the renal epithelial tissue comprising renal tubular epithelial cells, the renal epithelial tissue in contact with the layer of renal interstitial tissue to form a three-dimensional, engineered, biological renal tissue. Also disclosed are methods of fabricating and using the same.
    Type: Application
    Filed: October 6, 2015
    Publication date: April 7, 2016
    Inventors: Deborah Lynn Greene NGUYEN, Shelby Marie KING, Sharon C. PRESNELL
  • ENGINEERED THREE-DIMENSIONAL BREAST TISSUE, ADIPOSE TISSUE, AND TUMOR DISEASE MODEL
    Publication number: 20150282885
    Abstract: Described are three-dimensional, engineered, biological breast tissues, adipose tissues, and tumor models, including breast cancer models.
    Type: Application
    Filed: April 3, 2015
    Publication date: October 8, 2015
    Inventors: Shelby Marie KING, Deborah Lynn Greene NGUYEN, Vivian A. GORGEN, Benjamin R. SHEPHERD, Sharon C. PRESNELL