Patents by Inventor Deborah O'Neil

Deborah O'Neil has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ANTI-VIRAL THERAPY
    Publication number: 20230338310
    Abstract: The invention relates to the use of compounds, and compositions comprising such compounds, for treating viral infection. More specifically, the compounds for use in the invention are comprised of structural formula (1), or a pharmaceutically acceptable salt thereof. The invention also relates to the compounds for use in treating hyperinflammation.
    Type: Application
    Filed: May 25, 2021
    Publication date: October 26, 2023
    Inventors: Deborah O'NEIL, Douglas FRASER-PITT
  • Microparticles comprising a sulphur-containing compound
    Patent number: 11369568
    Abstract: The present invention provides microparticles comprising a sulphur-containing compound, such as cysteamine, or a pharmaceutically acceptable salt, hydrate or ester thereof. Also provided is a composition comprising the microparticles and a stabilizing agent.
    Type: Grant
    Filed: June 6, 2017
    Date of Patent: June 28, 2022
    Assignee: NOVABIOTICS LIMITED
    Inventor: Deborah O'Neil
  • DOSAGE REGIME
    Publication number: 20210386694
    Abstract: The present disclosure relates to use of cysteamine, formulations comprising cysteamine and pharmaceutically acceptable salts of cysteamine in the treatment of cystic fibrosis and conditions associated with cystic fibrosis.
    Type: Application
    Filed: October 17, 2019
    Publication date: December 16, 2021
    Inventor: Deborah O'Neil
  • Antimicrobial compositions with cysteamine
    Patent number: 11020414
    Abstract: The invention relates to products comprising an antibiotic agent and a second agent being a dispersant or an anti-adhesive agent, in particular a mucolytic dispersant or a mucolytic anti-adhesive agent, which are useful in relation to the prevention and treatment of bacterial infections.
    Type: Grant
    Filed: February 11, 2016
    Date of Patent: June 1, 2021
    Assignee: NOVABIOTICS LIMITED
    Inventors: Deborah O'Neil, Cedric Charrier
  • Microparticles
    Patent number: 10905660
    Abstract: The present invention provides microparticles comprising a sulphur-containing compound, such as cysteamine, or a pharmaceutically acceptable salt, hydrate or ester thereof. Also provided is a composition comprising the microparticles and a stabilizing agent.
    Type: Grant
    Filed: June 6, 2017
    Date of Patent: February 2, 2021
    Assignee: NOVABIOTICS LIMITED
    Inventor: Deborah O'Neil
  • INHIBITION OF BIOFILM ORGANISMS
    Publication number: 20190175528
    Abstract: The present invention relates to a product comprising at least two antibiofilm agents wherein at least one of the antibiofilm agents is an antimicrobial peptide. The second antibiofilm agent is cysteamine. There is also provided the use of the product in the treatment of a microbial infection.
    Type: Application
    Filed: February 13, 2019
    Publication date: June 13, 2019
    Inventors: Deborah O'Neil, Derry Mercer, Cedric Charrier
  • MICROPARTICLES COMPRISING A SULPHUR-ONTAINING COMPOUND
    Publication number: 20190175501
    Abstract: The present invention provides microparticles comprising a sulphur-containing compound, such as cysteamine, or a pharmaceutically acceptable salt, hydrate or ester thereof Also provided is a composition comprising the microparticles and a stabilizing agent.
    Type: Application
    Filed: June 6, 2017
    Publication date: June 13, 2019
    Inventor: Deborah O'NEIL
  • Cysteamine as Neutrophil Elastase Inhibitor
    Publication number: 20180344671
    Abstract: The present invention relates to compositions of cysteamine or a derivative thereof for use in the treatment or prophylaxis or a disease or condition associated with neutrophil elastase activity. The compositions can be administered, e.g., by inhalation, intravenously, or topically, as appropriate.
    Type: Application
    Filed: June 4, 2018
    Publication date: December 6, 2018
    Inventors: Deborah O'Neil, Douglas Fraser-Pitt
  • An Amino Thiol for Use in the Treatment of an Infection Caused by the Bacterium Mycobacterium Spp
    Publication number: 20180185305
    Abstract: The present invention relates to cysteamine, cystamine, or derivatives thereof, for use in the treatment and/or prevention of infection caused by the bacterium, Mycobacterium spp., in particular Mycobacterium abscessus, or a disease or condition associated therewith.
    Type: Application
    Filed: June 6, 2016
    Publication date: July 5, 2018
    Inventors: Deborah O'NEIL, Douglas FRASER-PITT
  • Treatment of Drug-Resistant Microbial Infections
    Publication number: 20170348253
    Abstract: The present invention provides a sulphur-containing compound for use in the prophylaxis or treatment of an infection associated with at least one microbe or microbial strain displaying at least some degree of drug resistance. Also provided is a product comprising a first agent being a sulphur-containing compound and a second agent being an antimicrobial agent, in particular an antibiotic agent.
    Type: Application
    Filed: June 6, 2017
    Publication date: December 7, 2017
    Inventors: Deborah O'NEIL, Douglas FRASER-PITT
  • MICROPARTICLES
    Publication number: 20170348254
    Abstract: The present invention provides microparticles comprising a sulphur-containing compound, such as cysteamine, or a pharmaceutically acceptable salt, hydrate or ester thereof. Also provided is a composition comprising the microparticles and a stabilizing agent.
    Type: Application
    Filed: June 6, 2017
    Publication date: December 7, 2017
    Inventor: Deborah O'NEIL
  • FORMULATION
    Publication number: 20170348381
    Abstract: The present disclosure relates to an aqueous composition of an antifungal peptide, to methods of treatment using the composition and to uses of the composition.
    Type: Application
    Filed: June 5, 2017
    Publication date: December 7, 2017
    Inventor: Deborah O'NEIL
  • Antibiotic compositions comprising an antibiotic agent and cysteamine
    Patent number: 9782423
    Abstract: The invention relates to products comprising an antibiotic agent and a second agent being a dispersant or an anti-adhesive agent, in particular a mucolytic dispersant or a mucolytic anti-adhesive agent, which are useful in relation to the prevention and treatment of bacterial infections.
    Type: Grant
    Filed: June 1, 2012
    Date of Patent: October 10, 2017
    Assignee: Novabiotics Limited
    Inventors: Deborah O'Neil, Cedric Charrier
  • Modified Antimicrobial Peptides
    Publication number: 20170107254
    Abstract: The present invention relates to modified antimicrobial peptides which incorporate a histidine tag, are conjugated with a fatty acid and/or are PEGylated and their use in the treatment of microbial infections.
    Type: Application
    Filed: April 2, 2015
    Publication date: April 20, 2017
    Inventors: Deborah O'NEIL, Derry MERCER, Vanessa DUNCAN
  • Topical formulation of arginine-rich cyclic antimicrobial peptides
    Patent number: 9518093
    Abstract: The present invention relates to cyclic cationic peptides and their use in the treatment of microbial infections.
    Type: Grant
    Filed: November 9, 2015
    Date of Patent: December 13, 2016
    Assignee: NOVABIOTICS LIMITED
    Inventor: Deborah O'Neil
  • Inhibition of Biofilm Organisms
    Publication number: 20160206575
    Abstract: The present invention relates to a product comprising at least two antibiofilm agents wherein at least one of the antibiofilm agents is an antimicrobial peptide. The second antibiofilm agent is cysteamine. There is also provided the use of the product in the treatment of a microbial infection.
    Type: Application
    Filed: March 28, 2016
    Publication date: July 21, 2016
    Applicant: NOVABIOTICS LIMITED
    Inventors: Deborah O'NEIL, Derry MERCER, Cedric CHARRIER
  • Peptides and their use
    Patent number: 9371363
    Abstract: The invention relates to peptides, and peptide variants thereof, in which substantially all of the amino acids in the amino sequence of said peptide are the same, for use as antibacterial agents.
    Type: Grant
    Filed: January 28, 2008
    Date of Patent: June 21, 2016
    Assignee: Novabiotics Limited
    Inventor: Deborah O'Neil
  • Cyclic Antimicrobial Peptides
    Publication number: 20160168203
    Abstract: The present invention relates to cyclic cationic peptides and their use in the treatment of microbial infections.
    Type: Application
    Filed: November 9, 2015
    Publication date: June 16, 2016
    Applicant: NOVABIOTICS LIMITED
    Inventor: Deborah O'NEIL
  • Antimicrobial compositions with cysteamine
    Patent number: 9364491
    Abstract: The invention relates to products comprising an antibiotic agent and a second agent being a dispersant or an anti-adhesive agent, in particular a mucolytic dispersant or a mucolytic anti-adhesive agent, which are useful in relation to the prevention and treatment of bacterial infections.
    Type: Grant
    Filed: August 15, 2014
    Date of Patent: June 14, 2016
    Assignee: NOVABIOTICS LIMITED
    Inventors: Deborah O'Neil, Cedric Charrier
  • Antimicrobial Compositions with Cysteamine
    Publication number: 20160158169
    Abstract: The invention relates to products comprising an antibiotic agent and a second agent being a dispersant or an anti-adhesive agent, in particular a mucolytic dispersant or a mucolytic anti-adhesive agent, which are useful in relation to the prevention and treatment of bacterial infections.
    Type: Application
    Filed: February 11, 2016
    Publication date: June 9, 2016
    Applicant: NOVABIOTICS LIMITED
    Inventors: Deborah O'NEIL, Cedric CHARRIER