Patents by Inventor Deborah O'Neil

Deborah O'Neil has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Inhibition of biofilm organisms
    Patent number: 9339525
    Abstract: The present invention relates to a product comprising at least two antibiofilm agents wherein at least one of the antibiofilm agents is an antimicrobial peptide. The second antibiofilm agent is cysteamine. There is also provided the use of the product in the treatment of a microbial infection.
    Type: Grant
    Filed: March 31, 2010
    Date of Patent: May 17, 2016
    Assignee: Novabiotics Limited
    Inventors: Deborah O'Neil, Derry Mercer, Cedric Charrier
  • USE
    Publication number: 20160106689
    Abstract: The present invention relates to compositions comprising cysteamine or a derivative thereof for use in treating infections caused by yeasts or moulds.
    Type: Application
    Filed: September 22, 2015
    Publication date: April 21, 2016
    Applicant: NOVABIOTICS LIMITED
    Inventor: Deborah O'NEIL
  • Use of Cysteamine in Treating Infections caused by Yeasts/Moulds
    Publication number: 20160102052
    Abstract: The present invention relates to compositions comprising cysteamine or a derivative thereof for use in treating infections caused by yeasts or moulds.
    Type: Application
    Filed: September 22, 2015
    Publication date: April 14, 2016
    Applicant: Novabiotics Limited
    Inventors: Deborah O'NEIL, Vanessa DUNCAN
  • Treatment of bacterial infections with cyclic antimicrobial peptides
    Patent number: 9181303
    Abstract: The present invention relates to cyclic cationic peptides and their use in the treatment of microbial infections.
    Type: Grant
    Filed: June 20, 2014
    Date of Patent: November 10, 2015
    Assignee: NovaBiotics Limited
    Inventor: Deborah O'Neil
  • Peptides and their use
    Patent number: 9169290
    Abstract: The present invention relates to peptides for use as antifungal agents. The peptides comprise a sequence of 5 to 15 basic amino acids wherein substantially all of the amino acids in said sequence are the same.
    Type: Grant
    Filed: January 28, 2008
    Date of Patent: October 27, 2015
    Assignee: NovaBiotics Limited
    Inventor: Deborah O'Neil
  • Composition
    Publication number: 20140357592
    Abstract: The invention relates to products comprising an antibiotic agent and a second agent being a dispersant or an anti-adhesive agent, in particular a mucolytic dispersant or a mucolytic anti-adhesive agent, which are useful in relation to the prevention and treatment of bacterial infections.
    Type: Application
    Filed: August 15, 2014
    Publication date: December 4, 2014
    Applicant: NOVABIOTICS LIMITED
    Inventors: Deborah O'NEIL, Cedric CHARRIER
  • Compounds and their use
    Patent number: 8901071
    Abstract: The present invention relates to peptides and their use in the treatment of microbial infections, in particular bacterial infections. In particular, the invention relates to peptides wherein at least 75% of the amino acids of the peptide are arginine and phenylalanine amino acids, at least 50% of the amino acids being arginine amino acids and at least 15% of the amino acids being phenylalanine amino acids.
    Type: Grant
    Filed: March 30, 2011
    Date of Patent: December 2, 2014
    Assignee: Novabiotics Limited
    Inventors: Deborah O'Neil, Derry Mercer, Cedric Charrier
  • CYCLIC ANTIMICROBIAL PEPTIDES
    Publication number: 20140303071
    Abstract: The present invention relates to cyclic cationic peptides and their use in the treatment of microbial infections.
    Type: Application
    Filed: June 20, 2014
    Publication date: October 9, 2014
    Inventor: Deborah O'NEIL
  • Cyclic antimicrobial peptides for treating bacterial infections
    Patent number: 8785375
    Abstract: The present invention relates to cyclic cationic peptides and their use in the treatment of microbial infections.
    Type: Grant
    Filed: August 22, 2012
    Date of Patent: July 22, 2014
    Assignee: Novabiotics Ltd.
    Inventor: Deborah O'Neil
  • Polypeptides and Their Use
    Publication number: 20140155321
    Abstract: The present invention relates to a polypeptide or a product comprising said polypeptide for use in the treatment and/or prevention of a fungal infection caused by Malassezia spp. and/or a Malassezia spp associated condition wherein the polypeptide comprises a sequence of about 25 to 200 amino acids wherein substantially all of the amino acids in said sequence are lysine; pharmaceutical compositions comprising said polypeptide or product and uses thereof.
    Type: Application
    Filed: March 14, 2013
    Publication date: June 5, 2014
    Applicant: Novabiotics Limited
    Inventors: Deborah O'NEIL, Derry MERCER, Colin STEWART
  • Method of treatment of bacterial infection by administration of poly-lysine
    Patent number: 8470769
    Abstract: The present invention relates to peptides comprising amino acids according to Formula I ((X)l(Y)m)n??(I) wherein l, m and n are integers from 0 to 10; X and Y, which may be the same or different, are an amino acid selected from the group consisting of hydrophobic amino acids and/or cationic amino acids, together with methods for the use of the peptides in the treatment of microbial infections.
    Type: Grant
    Filed: November 30, 2011
    Date of Patent: June 25, 2013
    Assignee: Novabiotics, Ltd.
    Inventor: Deborah O'Neil
  • Method of Establishing a Fungal Nail Infection
    Publication number: 20130109049
    Abstract: The present invention provides a method of infecting a nail fragment with a fungus, to form an infected nail fragment comprising at least 1×102 fungal colony forming units (cfu) per cm2 of the infected surface(s). There is also provided a method of assessing the efficacy of potential therapeutic compounds in the treatment or prevention of a fungal nail infection. The fungal nail infection may be a dermatophyte, a non-dermatophyte mould or a pathogen.
    Type: Application
    Filed: December 20, 2010
    Publication date: May 2, 2013
    Applicant: NOVABIOTICS LIMITED
    Inventors: Deborah O'Neil, Derry Mercer, Colin Stewart
  • Compounds And Their Use
    Publication number: 20130102524
    Abstract: The present invention relates to peptides and their use in the treatment of microbial infections, in particular bacterial infections. In particular, the invention relates to peptides wherein at least 75% of the amino acids of the peptide are arginine and phenylalanine amino acids, at least 50% of the amino acids being arginine amino acids and at least 15% of the amino acids being phenylalanine amino acids.
    Type: Application
    Filed: March 30, 2011
    Publication date: April 25, 2013
    Applicant: Novabiotics Limited
    Inventors: Deborah O'Neil, Derry Mercer, Cedric Charrier
  • Method of treatment of non-dermatophytic fungal infections
    Patent number: 8350003
    Abstract: The present invention relates to peptides comprising amino acids according to Formula I ((X)l(Y)m)n ??(I) wherein l, m and n are integers from 0 to 10; X and Y, which may be the same or different, are an amino acid selected from the group consisting of hydrophobic amino acids and/or cationic amino acids, together with methods for the use of the peptides in the treatment of microbial infections.
    Type: Grant
    Filed: June 28, 2011
    Date of Patent: January 8, 2013
    Assignee: Novabiotics Limited
    Inventor: Deborah O'Neil
  • COMPOSITION
    Publication number: 20120328671
    Abstract: The invention relates to products comprising an antibiotic agent and a second agent being a dispersant or an anti-adhesive agent, in particular a mucolytic dispersant or a mucolytic anti-adhesive agent, which are useful in relation to the prevention and treatment of bacterial infections.
    Type: Application
    Filed: June 1, 2012
    Publication date: December 27, 2012
    Applicant: NOVABIOTICS LIMITED
    Inventors: Deborah O'Neil, Cedric Charrier
  • CYCLIC ANTIMICROBIAL PEPTIDES
    Publication number: 20120316103
    Abstract: The present invention relates to cyclic cationic peptides and their use in the treatment of microbial infections.
    Type: Application
    Filed: August 22, 2012
    Publication date: December 13, 2012
    Applicant: NOVABIOTICS LIMITED
    Inventor: Deborah O'NEIL
  • Treatment of fungal infections with cyclic antimicrobial peptides
    Patent number: 8324154
    Abstract: The present invention relates to cyclic cationic peptides and their use in the treatment of microbial infections.
    Type: Grant
    Filed: December 21, 2006
    Date of Patent: December 4, 2012
    Assignee: Novabiotics, Ltd.
    Inventor: Deborah O'Neil
  • INHIBITION OF BIOFILM ORGANISMS
    Publication number: 20120189682
    Abstract: The present invention relates to a product comprising at least two antibiofilm agents wherein at least one of the antibiofilm agents is an antimicrobial peptide. The second antibiofilm agent is generally a dispersant or an anti-adhesive agent. There is also provided the use of the product in the treatment of a microbial infection.
    Type: Application
    Filed: March 31, 2010
    Publication date: July 26, 2012
    Applicant: Novabiotics Limited
    Inventors: Deborah O'Neil, Derry Mercer, Cedric Charrier
  • ANTI-MICROBIAL PEPTIDES
    Publication number: 20120071398
    Abstract: The present invention relates to peptides comprising amino acids according to Formula I ((X)l(Y)m)n??(I) wherein l, m and n are integers from 0 to 10; X and Y, which may be the same or different, are an amino acid selected from the group consisting of hydrophobic amino acids and/or cationic amino acids, together with methods for the use of the peptides in the treatment of microbial infections.
    Type: Application
    Filed: November 30, 2011
    Publication date: March 22, 2012
    Applicant: NOVABIOTICS LIMITED
    Inventor: Deborah O'Neil
  • Method of treatment of a fungal infection with poly arginine peptides
    Patent number: 8088888
    Abstract: The present invention relates to peptides comprising amino acids according to Formula I ((X)l(Y)m)n??(I) wherein l, m and n are integers from 0 to 10; X and Y, which may be the same or different, are an amino acid selected from the group consisting of hydrophobic amino acids and/or cationic amino acids, together with methods for the use of the peptides in the treatment of microbial infections.
    Type: Grant
    Filed: September 29, 2010
    Date of Patent: January 3, 2012
    Assignee: NovaBiotics Limited
    Inventor: Deborah O'Neil