Abstract: Coating compositions are provided which include a polysiloxane comprising at least one reactive functional group and at least one material comprising at least one reactive functional group. Also provided are multi-layer composite coatings formed from a basecoat deposited from a pigmented coating composition and a topcoat applied over the basecoat, the topcoat deposited from the aforementioned coating composition. A method for improving the scratch resistance of a coated substrate, as well as coated substrates also are provided. The compositions of the invention provide highly scratch resistant coatings, particularly highly scratch resistant color-plus-clearcoatings.

Abstract: Provided herein are alphavirus vectors derived from South African Arbovirus No. 86 (S.A.AR86) comprising attenuating mutations and methods of making the same. Also provided are improved viral vectors and helper constructs comprising a S.A.AR86 capsid enhancer sequence. The present invention also provides S.A.AR86 replicon and helper constructs comprising an alphavirus capsid enhancer sequence. Further provided are methods of administering an alphavirus vector comprising a heterologous nucleotide sequence (preferably encoding an immunogen or a therapeutic polypeptide) according to the invention to a cell or subject. In preferred embodiments, the alphavirus vector delivers the heterologous nucleotide sequence to the cells of the bone, bone marrow, and/or bone-associated connective tissue.

Abstract: A convertible ladder having a first ladder section and a second ladder section. The first ladder section and the second ladder section each include a pair of side rails and at least one rung that extends between the side rails. The first ladder section further includes a pair of upper rail guides and a pair of intermediate rail guides. One of the upper rail guides is attached to each of the second side rails proximate an upper end thereof. One of the intermediate rail guides is attached to each of the second side rails intermediate the upper end and the lower end. The upper rail guides and the intermediate rail guides each include a recess that is adapted to at least partially receive one of the first side rails.

Abstract: A collapsible utility trailer having a trailer bed, a trailer frame, a front pair of wheels and a rear pair of wheels. The trailer bed has at least two bed sections and each of the bed sections has a length and a width. The trailer frame has a plurality of frame sections and each of the trailer frame sections have a length and a width that are less than the length and the width of the bed sections, respectively. The trailer bed sections are attached to the trailer frame. The front and rear pairs of wheels rotatably attached to the trailer frame so that the front and rear wheels are oriented substantially below the trailer bed.

Abstract: A collapsible utility trailer having a trailer bed, a trailer frame, a front pair of wheels and a rear pair of wheels. The trailer bed has at least two bed sections and each of the bed sections has a length and a width. The trailer frame has a plurality of frame sections and each of the trailer frame sections have a length and a width that are less than the length and the width of the bed sections, respectively. The trailer bed sections are attached to the trailer frame. The front and rear pairs of wheels rotatably attached to the trailer frame so that the front and rear wheels are oriented substantially below the trailer bed.

Abstract: A ladder having a first ladder section, a second ladder section, an adjustable hinge mechanism, an engagement indicator and a static hinge mechanism. The adjustable hinge mechanism is mounted with respect to the first ladder and the second ladder so that the adjustable hinge mechanism is moveable between an engaged position and a disengaged position. The static hinge mechanism enables the first and second ladder sections to be maintained in a stationary position with respect to each other.

Abstract: A convertible ladder including a first ladder portion, a second ladder portion and a static hinge mechanism. The first ladder portion has a first locking mechanism proximate a first end thereof. The second ladder portion has a second locking mechanism proximate a first end thereof. The static hinge mechanism is attached to the first ladder portion with the first locking mechanism. The static hinge mechanism is attached to the second ladder portion with the second locking mechanism. The static hinge mechanism maintains the first ladder portion in a stationary relation with respect to the second ladder portion.

Abstract: A ladder including a first ladders rail, a second ladder rail, a first step and a support brace. The first ladder rail has a first rail front side, a first rail rear side, and a first rail web that extends between the first rail front side and the first rail rear side. The second ladder rail has a second rail front side, a second rail rear side, and a second rail web that extends between the second rail front side and the second rail rear side. The first step is attached to the first ladder rail and the second ladder rail.

Abstract: The present invention provides an improved multi-layer composite of two or more polymeric layers at least one of which is formed from a thermosetting composition. The composite includes at least a first polymeric layer formed on a substrate and a second polymeric layer over the first polymeric layer, wherein in the absence of a boron-containing compound, the first and second polymeric layers have poor interlayer adhesion. The improvement resides in the inclusion of at least one boron-containing compound in one or both of the first and second polymeric layers in an amount sufficient to improve the interlayer adhesion between the first and second polymeric layers. Also provided is an improved curable coating composition used to form a multi-layer composite coating of two or more cured coating layers, at least one of which is formed from the thermosetting composition. Related methods and coated substrates are also provided.

Abstract: A ladder having a first ladder section, a second ladder section, an adjustable hinge mechanism, an engagement indicator and a static hinge mechanism. The adjustable hinge mechanism is mounted with respect to the first ladder and the second ladder so that the adjustable hinge mechanism is moveable between an engaged position and a disengaged position. The static hinge mechanism enables the first and second ladder sections to be maintained in a stationary position with respect to each other.

Abstract: Coating compositions are provided which are formed from components comprising (a) at least one polysiloxane comprising at least one reactive functional group; (b) at least one reactant comprising at least one functional group that is reactive with at least one functional group selected from the at least one reactive functional group of the at least one polysiloxane and at least one functional group of at least one reactant; and (c) a plurality of particles, wherein each component is different, and wherein the at least one reactive functional group of the at least one polysiloxane and the at least one functional group of the at least one reactant are substantially nonreactive with the particles. A multi-component composite coating composition formed from a basecoat and a topcoat deposited from the curable coating composition also is provided.

Abstract: A coating composition that can be cured by actinic or ionizing radiation is disclosed.

Abstract: Compositions are provided which contain (a) one or more polysiloxanes comprising at least one reactive functional group; a plurality of particles; and, optionally, one or more curing agents comprising at least one functional group that is reactive with any reactive functional group of polysiloxane (a). Additionally, a process for applying the multi-component composite coatings described above to a substrate and coated substrates are provided. A process for preparing the coating compositions also is provided. The multi-component composite coating compositions of the invention provide highly scratch resistant color-plus-clearcoatings capable of retaining scratch resistance after weathering.

Abstract: Liquid coating compositions having improved mar and scratch resistance are disclosed. The coatings generally comprise one or more particles that have been modified to render the particles more surface active. The improved resistance is achieved without affecting the appearance or mechanical performance of the coatings. Methods for using the coatings, and the substrates coated therewith, are also disclosed.

Abstract: Compositions are provided which contain (a) one or more polysiloxanes comprising at least one reactive functional group; a plurality of particles; and optionally, one or more curing agents comprising at least one functional group that is reactive with any reactive functional group of polysiloxane (a). Additionally, a process for applying the multi-component composite coatings described above to a substrate and coated substrates are provided. A process for preparing the coating compositions also is provided. The multi-component composite coating compositions of the invention provide highly scratch resistant color-plus-clearcoatings capable of retaining scratch resistance after weathering.

Abstract: A process for forming a multilayer composite coating on a substrate is provided. The process includes forming an electrodeposition coating layer on the substrate by electrodeposition of a curable electrodepositable coating composition over at least a portion of the substrate. Optionally, the coated substrate is heated to a temperature and for a time sufficient to cure the electrodeposition coating layer. A basecoating layer is formed on the electrodeposition coating layer by depositing an aqueous curable basecoating composition directly onto at least a portion of the electrodeposition coating layer. Optionally, the basecoating layer is dehydrated. A top coating layer is formed on the basecoating layer by depositing a curable top coating composition which is substantially pigment-free directly onto at least a portion of the basecoating layer. The top coating layer, the basecoating layer, and, optionally, the electrodeposition coating layer are cured simultaneously.

Abstract: Coating compositions are provided which are formed from components comprising (a) at least one polysiloxane comprising at least one reactive functional group; (b) at least one reactant comprising at least one functional group that is reactive with at least one functional group selected from the at least one reactive functional group of the at least one polysiloxane and at least one functional group of at least one reactant; and (c) a plurality of particles, wherein each component is different, and wherein the at least one reactive functional group of the at least one polysiloxane and the at least one functional group of the at least one reactant are substantially nonreactive with the particles. A multi-component composite coating composition formed from a basecoat and a topcoat deposited from the curable coating composition also is provided.

Abstract: Coating compositions are provided which include a polysiloxane comprising at least one reactive functional group and at least one material comprising at least one reactive functional group. Also provided are multi-layer composite coatings formed from a basecoat deposited from a pigmented coating composition and a topcoat applied over the basecoat, the topcoat deposited from the aforementioned coating composition. A method for improving the scratch resistance of a coated substrate, as well as coated substrates also are provided. The compositions of the invention provide highly scratch resistant coatings, particularly highly scratch resistant color-plus-clearcoatings.

Abstract: Provided herein are alphavirus vectors derived from South African Arbovirus No. 86 (S.A.AR86) comprising attenuating mutations and methods of making the same. Also provided are improved viral vectors and helper constructs comprising a S.A.AR86 capsid enhancer sequence. The present invention also provides S.A.AR86 replicon and helper constructs comprising an alphavirus capsid enhancer sequence. Further provided are methods of administering an alphavirus vector comprising a heterologous nucleotide sequence (preferably encoding an immunogen or a therapeutic polypeptide) according to the invention to a cell or subject. In preferred embodiments, the alphavirus vector delivers the heterologous nucleotide sequence to the cells of the bone, bone marrow, and/or bone-associated connective tissue.

Abstract: A stepladder that includes a first frame, a second frame, a step, a utility tray and a support arm. The second frame is pivotally attached to the first frame. The step is operably connected to the first frame and the second frame. The step pivots with respect to at least one of the first frame and the second frame as the first frame is pivoted with respect to the second frame. The utility tray is pivotally connected to the second frame and includes a top panel and a side panel. The top panel has a first end and a second end. The side panel extends from the top panel along a side of the top panel that extends between the first end and the second end. The side panel has a slot formed therein. The side panel has a detent formed therein. The detent is in communication with the slot. The support arm has a first end and a second end. The first end of the support arm is pivotally connected to the second frame.