Patents by Inventor Dennis Yamashita

Dennis Yamashita has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Beta-Arrestin Effectors And Compositions And Methods Of Use Thereof
    Publication number: 20140357562
    Abstract: This application describes a family of compounds acting as ?-arrestin effectors. Such compounds may provide significant therapeutic benefit in the treatment of chronic and acute cardiovascular diseases.
    Type: Application
    Filed: August 15, 2014
    Publication date: December 4, 2014
    Inventors: Dennis Yamashita, Xiao-Tao Chen
  • Beta-Arrestin Effectors And Compositions And Methods Of Use Thereof
    Publication number: 20140336123
    Abstract: This application describes a family of compounds acting as ?-arrestin effectors. Such compounds may provide significant therapeutic benefit in the treatment of chronic and acute cardiovascular diseases.
    Type: Application
    Filed: August 1, 2014
    Publication date: November 13, 2014
    Inventors: Dennis Yamashita, Xiao-Tao Chen
  • Opioid receptor ligands and methods of using and making same
    Patent number: 8835488
    Abstract: This application describes compounds that can act as opioid receptor ligands, which compounds can be used in the treatment of, for example, pain and pain related disorders.
    Type: Grant
    Filed: March 23, 2012
    Date of Patent: September 16, 2014
    Assignee: Trevena, Inc.
    Inventors: Dennis Yamashita, Dimitar Gotchev, Philip Pitis, Xiao-Tao Chen, Guodong Liu, Catherine C. K. Yuan
  • ?-arrestin effectors and compositions and methods of use thereof
    Patent number: 8809260
    Abstract: This application describes a family of compounds acting as ?-arrestin effectors. Such compounds may provide significant therapeutic benefit in the treatment of chronic and acute cardiovascular diseases.
    Type: Grant
    Filed: June 24, 2013
    Date of Patent: August 19, 2014
    Assignee: Trevena, Inc.
    Inventors: Dennis Yamashita, Xiao-Tao Chen
  • ?-arrestin effectors and compositions and methods of use thereof
    Patent number: 8796204
    Abstract: This application describes a family of compounds acting as ?-arrestin effectors. Such compounds may provide significant therapeutic benefit in the treatment of chronic and acute cardiovascular diseases.
    Type: Grant
    Filed: June 25, 2013
    Date of Patent: August 5, 2014
    Assignee: Trevena, Inc.
    Inventors: Dennis Yamashita, Xiao-Tao Chen
  • Beta-Arrestin Effectors And Compositions And Methods Of Use Thereof
    Publication number: 20140005114
    Abstract: This application describes a family of compounds acting as ?-arrestin effectors. Such compounds may provide significant therapeutic benefit in the treatment of chronic and acute cardiovascular diseases.
    Type: Application
    Filed: June 25, 2013
    Publication date: January 2, 2014
    Applicant: Trevena, Inc.
    Inventors: Dennis Yamashita, Xiao-Tao Chen
  • Opioid Receptor Ligands and Methods of Using and Making Same
    Publication number: 20130331408
    Abstract: This application describes compounds that can act as opioid receptor ligands, which compounds can be used in the treatment of, for example, pain and pain related disorders.
    Type: Application
    Filed: August 12, 2013
    Publication date: December 12, 2013
    Applicant: Trevena, Inc.
    Inventors: Dennis Yamashita, Dimitar Gotchev, Philip Pitis, Xiao-Tao Chen, Guodong Liu, Catherine C.K. Yuan
  • BETA-ARRESTIN EFFECTORS AND COMPOSITIONS AND METHODS OF USE THEREOF
    Publication number: 20130274176
    Abstract: This application describes a family of compounds acting as ?-arrestin effectors. Such compounds may provide significant therapeutic benefit in the treatment of chronic and acute cardiovascular diseases.
    Type: Application
    Filed: June 24, 2013
    Publication date: October 17, 2013
    Applicant: Trevena, Inc.
    Inventors: Dennis Yamashita, Xiao-Tao Chen
  • Beta-Arrestin Effectors and Compositions and Methods of Use Thereof
    Publication number: 20130196902
    Abstract: This application describes compounds acting as, for example, ?-arrestin effectors and uses thereof, in, for example, the treatment of chronic and acute cardiovascular diseases.
    Type: Application
    Filed: January 31, 2013
    Publication date: August 1, 2013
    Applicant: Trevena, Inc.
    Inventors: Dennis Yamashita, Xiao Tao Chen
  • ?-arrestin effectors and compositions and methods of use thereof
    Patent number: 8486885
    Abstract: This application describes a family of compounds acting as ?-arrestin effectors. Such compounds may provide significant therapeutic benefit in the treatment of chronic and acute cardiovascular diseases.
    Type: Grant
    Filed: December 28, 2009
    Date of Patent: July 16, 2013
    Assignee: Trevena, Inc.
    Inventors: Dennis Yamashita, Xiao-Tao Chen
  • OPIOID RECEPTOR LIGANDS AND METHODS OF USING AND MAKING SAME
    Publication number: 20120245181
    Abstract: This application describes compounds that can act as opioid receptor ligands, which compounds can be used in the treatment of, for example, pain and pain related disorders.
    Type: Application
    Filed: March 23, 2012
    Publication date: September 27, 2012
    Applicant: Trevena, Inc.
    Inventors: Dennis Yamashita, Dimitar Gotchev, Philip Pitis, Xiao-Tao Chen, Guodong Liu, Catherine C.K. Yuan
  • Beta-Arrestin Effectors And Compositions And Methods Of Use Thereof
    Publication number: 20100184701
    Abstract: This application describes a family of compounds acting as ?-arrestin effectors. Such compounds may provide significant therapeutic benefit in the treatment of chronic and acute cardiovascular diseases.
    Type: Application
    Filed: December 28, 2009
    Publication date: July 22, 2010
    Inventors: Dennis Yamashita, Xiao-Tao Chen
  • Reversed Pyrimidinone Compounds as Calcilytics
    Publication number: 20070270446
    Abstract: Calcilytic compounds and methods of preparing them are disclosed. Methods of using the calcilytic compounds are also provided.
    Type: Application
    Filed: October 6, 2005
    Publication date: November 22, 2007
    Applicant: SMITHKLINE BEECHAM CORPORATION
    Inventors: Robert Marquis Jr, Jae Jeong, Juan Luengo, Dennis Yamashita
  • Calcilytic Compounds
    Publication number: 20070232628
    Abstract: Novel calcilytic compounds and methods of using them are provided.
    Type: Application
    Filed: May 3, 2005
    Publication date: October 4, 2007
    Inventors: Juan Luengo, Robert Marquis, Ren Xie, Dennis Yamashita
  • Pyrimidinone Compounds As Calcilytics
    Publication number: 20070197555
    Abstract: The pyrimidinone compounds are disclosed. Methods of preparing the pyrimidinone compounds are also disclosed.
    Type: Application
    Filed: April 7, 2004
    Publication date: August 23, 2007
    Inventors: Irina Shcherbakova, Manuel Balandrin, Guangfei Huang, Otto Geoffroy, John Fox, Robert Marquis, Dennis Yamashita, Juan Luengo, Wenyong Wang
  • Inhibitors of akt activity
    Publication number: 20070185152
    Abstract: Invented are novel pyridine compounds, the use of such compounds as inhibitors of PKB/AKT kinase activity and in the treatment of cancer and arthritis.
    Type: Application
    Filed: March 2, 2005
    Publication date: August 9, 2007
    Inventors: Dennis Yamashita, Hong Lin, Wenyong Wang
  • Protease inhibitors
    Publication number: 20060194787
    Abstract: The present invention provides C1-6alkyl-4-amino-azepan-3-one protease inhibitors and pharmaceutically acceptable salts, hydrates and solvates thereof which inhibit proteases, including cathepsin K, pharmaceutical compositions of such compounds, novel intermediates of such compounds, and methods for treating diseases of excessive bone loss or cartilage or matrix degradation, including osteoporosis; gingival disease including gingivitis and periodontitis; arthritis, more specifically, osteoarthritis and rheumatoid arthritis; Paget's disease; hypercalcemia of malignancy; and metabolic bone disease; and parasitic diseases, including malaria, by administering to a patient in need thereof one or more compounds of the present invention.
    Type: Application
    Filed: April 25, 2006
    Publication date: August 31, 2006
    Inventors: Maxwell Cummings, Robert Marquis, Yu Ru, Scott Thompson, Daniel Veber, Dennis Yamashita
  • Protease inhibitors
    Publication number: 20050256100
    Abstract: This invention relates in general to certain substituted 3,7-dioxoazepan-4-ylamides of formula 1 which are protease inhibitors.
    Type: Application
    Filed: May 21, 2003
    Publication date: November 17, 2005
    Inventors: Jae Jeong, Dennis Yamashita
  • Protease inhibitors
    Publication number: 20050256105
    Abstract: This invention relates in general to certain 5-substituted-6-oxo-[1,2]diazepanes of Formula I as defined herein, which are protease inhibitors.
    Type: Application
    Filed: May 21, 2003
    Publication date: November 17, 2005
    Inventors: Jae Jeong, Dennis Yamashita
  • Protease inhibitors
    Publication number: 20050256104
    Abstract: The present invention provides 4-amino-azepan-3-one protease inhibitors and pharmaceutically acceptable salts, hydrates and solvates thereof which inhibit proteases, including cathepsin K, pharmaceutical compositions of such compounds, novel intermediates of such compounds, and methods for treating diseases of excessive bone loss or cartilage or matrix degradation, including osteoporosis; gingival disease including gingivitis and periodontitis; arthritis, more specifically, osteoarthritis and rheumatoid arthritis; Paget's disease; hypercalcemia of malignancy; and metabolic bone disease, comprising inhibiting said bone loss or excessive cartilage or matrix degradation by administering to a patient in need thereof a compound of the present invention.
    Type: Application
    Filed: June 14, 2005
    Publication date: November 17, 2005
    Inventors: Robert Marquis, Yu Ru, Daniel Veber, Maxwell Cummings, Scott Thompson, Dennis Yamashita