Abstract: A method and device for protecting and installing a fire protection sprinkler assembly having a thermally responsive trigger. The method includes shielding and torqueing a fire protection sprinkler with a protective device having a torque assist portion. The protective device includes a first and second member strapped about the sprinkler assembly. Each of the members of the protective device has a first lateral end and a second lateral end disposed about the thermally responsive trigger. At least one of members has a concave segment and a convex segment formed between the first lateral end and the second lateral end. The convex and concave segments define therebetween an external torque assist surface of the protective device that can be used to manually torque and install the sprinkler assembly.

Abstract: Cleaning compositions having engineered fatty acid alpha-dioxygenases and methods of using said compositions to provide a benefit by converting long chain fatty acids present in soils into 2-hydroperoxy fatty acids or terminal aldehydes.

Abstract: A proportioner having a body portion that defines a foam passage and a fluid passage. The proportioner also includes a restrictor assembly having a restrictor disk and an orifice plate having an opening for receiving the restrictor disk. The proportioner can further include a rod member connected to the restrictor disk and a clapper assembly connected to the rod member via a sliding interface. The clapper assembly can be configured to control a flow of the foam concentrate through the foam passage in proportion to a flow of the fire protection fluid through the fluid passage by moving the rod member to vary the distance between the restrictor disk and the orifice plate. The sliding interface can be disposed between a first guide and a second guide, and at least a portion of the restrictor disk is disposed in the opening.

Abstract: Far-side inflatable airbag assemblies are disclosed to be installed to deploy adjacent an occupant during a far-side collision event or a far-side oblique collision event, and may retain the occupant at the occupant's vehicle occupant position to protect the occupant from collision with structures within the vehicle, as well as from collisions with other occupants of the vehicle. The far-side inflatable airbag assemblies of the present disclosure may be particularly beneficial when installed between vehicle occupant positions of the vehicle.

Abstract: Various aspects of upper arm prosthetic system for a human subject having a body and a partial arm are described. According to one aspect, the system may comprise any one or more of a force amplification apparatus, a terminal unit apparatus, and/or an adjustable elbow apparatus. Each apparatus may be body-powered and/or comprise 3D printable structures. Related upper arm prosthetic apparatus, kits, methods, and systems also are described.

Abstract: The disclosure provides methods for treating a subject in need thereof comprising administering to the subject a therapeutically-effective dose of psilocybin. The methods described herein may be used to treat a variety of diseases, disorders, and conditions. For example, the methods may be used to treat anxiety disorders, eating disorders, and headache disorders.

Abstract: The disclosure provides methods for treating a subject in need thereof comprising administering to the subject a therapeutically-effective dose of psilocybin. The methods described herein may be used to treat a variety of diseases, disorders, and conditions. For example, the methods may be used to treat depression, neurocognitive disorders, autism spectrum disorder, and/or attention-deficit/hyperactivity disorder.

Abstract: The disclosure provides methods for treating a subject in need thereof comprising administering to the subject a therapeutically-effective dose of psilocybin. The methods described herein may be used to treat a variety of diseases, disorders, and conditions. For example, the methods may be used to treat anxiety disorders, eating disorders, and headache disorders.

Abstract: One or more nodes on a network can run a network discovery service to obtain information regarding network configuration parameters for the nodes on the network by passively listening for packets received on one or more ports. The discovered network configuration data can be used to identify a configuration for various types of nodes. The configuration can then be used to facilitate checking, testing, or self-configuration of a network configuration of one of the nodes (e.g., a lead node or a new node).

Abstract: This invention relates to the large-scale production of psilocybin for use in medicine. More particularly, it relates to a method of obtaining high purity crystalline psilocybin, particularly, in the form of Polymorph A. It further relates to a method for the manufacture of psilocybin and intermediates in the production thereof and formulations containing psilocybin.

Abstract: This invention relates to the large-scale production of psilocybin for use in medicine. More particularly, it relates to a method of obtaining high purity crystalline psilocybin, particularly, in the form of Polymorph A. It further relates to a method for the manufacture of psilocybin and intermediates in the production thereof and formulations containing psilocybin.

Abstract: The invention provides a composition of matter which: (i) consists of at least 90% by weight of an atropisomer (2A) and 0-10% by weight of an atropisomer of formula (2B); or (ii) consists of at least 90% by weight of an atropisomer (2B) and 0-10% by weight of an atropisomer of formula (2A); wherein the atropisomer of formula (2A) and the atropisomer of formula (2B) are represented by: or are pharmaceutically acceptable salts or tautomers thereof, wherein ring X is a benzene or pyridine ring; ring Y is selected from a benzene ring, a pyridine ring and a thiophene ring; R1 is trifluoromethyl; R2 is hydrogen; R3 is hydrogen; m is 0 or 1; n is 0, 1 or 2; Ar1 is a monocyclic aromatic ring selected from benzene and pyridine; each monocyclic aromatic ring being unsubstituted or substituted with 1 or 2 substituents R5 as defined herein; and R4; R5 when present, R6 and R7 independently selected from various substituents as defined herein.

Abstract: An agitator may include one or more members adjustable between an expanded configuration and a compressed configuration. When the one or more members are in the expanded configuration, the agitator in a first set of two orthogonal dimensions is larger than an opening having a predetermined size. When the one or more members are in the compressed configuration, the agitator in a second set of two orthogonal dimensions is smaller than the opening having the predetermined size. The one or more members are biased to the expanded configuration in absence of external force applied to the one or more members. In use, the agitator may be inserted into a container through a neck of the container in the compressed configuration. The agitator may expand within the container so that the container does not fit through the neck of the container.

Abstract: The present disclosure provides (i) isolated immunogenic TAA polypeptides (i.e., an immunogenic MUC1 polypeptides, an immunogenic MSLN polypeptides, and an immunogenic TERT polypeptides), (ii) isolated nucleic acid molecules encoding one or more immunogenic TAA polypeptides, (iii) compositions comprising an immunogenic TAA polypeptide or an isolated nucleic acid molecule encoding an immunogenic TAA polypeptide, and (iv) methods relating to uses of the polypeptides, nucleic acid molecules, and compositions.

Abstract: This invention relates to the large-scale production of psilocybin for use in medicine. Move particularly, it relates to a method of obtaining high purity crystalline psilocybin, particularly, in the form of Polymorph A. It further relates to a method for the manufacture of psilocybin and intermediates in the production thereof and formulations containing psilocybin.

Abstract: Forming systems and methods for forming an elongate charge of composite material are disclosed herein. The forming systems include an elongate forming tool having an elongate forming surface with a forming surface shape that corresponds to a predetermined material shape for the elongate charge of composite material. The forming systems also include an elongate end effector, which is configured to tension the elongate charge of composite material across the forming surface. The elongate end effector includes an elongate vacuum distribution manifold, a porous elongate vacuum region, and an elongate friction surface. The methods include methods of tensioning an elongate charge of composite material across an elongate forming surface of an elongate forming tool utilizing an elongate end effector.

Abstract: Subtotal enclosures for inflatable airbag assemblies are disclosed that preserve a packaged state of the inflatable airbag assembly and that may be installed beneath or behind a seat covering material whereby “read-through” of the inflatable airbag assembly through the seat covering material is limited.

Abstract: The present disclosure relates to systems, non-transitory computer-readable media, and methods for receiving and integrating vehicle data for a fleet of different types of rental vehicles from across different databases to generate vehicle-data summaries for such rental vehicles—as well as for surfacing tools for dispatch, service, and other vehicle managing functions. In some cases, the disclosed systems further identifies and integrates service data from vehicle service centers associated with the rental vehicles into a central database and into the vehicle-data summaries. Such a fleet of rental vehicles can include personal-rental vehicles, provider-rental vehicles—such as express-provider-rental vehicles and flexible-provider-rental vehicles—as well as third-party-rental vehicles.

Abstract: A housing for storing an inflatable airbag includes a first portion and a second portion that cooperate to at least partially define a chamber for storing the inflatable airbag. A hinge portion connects the first portion to the second portion such that the second portion is pivotable about the hinge portion from a closed position for retaining the inflatable airbag within the chamber to an open position for deployment of the inflatable airbag from the chamber. A sacrificial seam connects the first portion and the second portion when the inflatable airbag is stored within the chamber. The sacrificial seam includes a plurality of connection members breakable in response to a pressure from within the chamber from initial inflation of the inflatable airbag. The connection members each extend across the sacrificial seam in a first direction between the first and second portions of the housing and are configured to have a predetermined failure area adjacent one of the first portion and the second portion.