Patents by Inventor Derek Lowe

Derek Lowe has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Pyrrolo[2,1-f][1,2,4]triazin-4-ylamines IGF-1R kinase inhibitors for the treatment of cancer and other hyperproliferative diseases
    Patent number: 8431695
    Abstract: This invention relates to novel compounds of formula (I). Formula (I) in which the variable groups are as defined in the specification and claims, to pharmaceutical compositions containing them, and to a method of treatment using them for treatment of cancer.
    Type: Grant
    Filed: November 2, 2006
    Date of Patent: April 30, 2013
    Assignee: Bayer Intellectual Property GmbH
    Inventors: Stephen O'Connor, Jacques Dumas, Wendy Lee, Julie Dixon, David Cantin, David Gunn, Jennifer Burke, Barton Phillips, Derek Lowe, Tatiana Shelekhin, Gan Wang, Xin Ma, Shihong Ying, Andrea McClure, Furahi Achebe, Mario Lobell, Frederick Ehrgott, Christiana Iwuagwu, Kyle Parcella
  • Pyrrolo[2,1-F] [1,2,4] Triazin-4-Ylamines IGF-1R Kinase Inhibitors for the Treatment of Cancer and Other Hyperproliferative Diseases
    Publication number: 20110294776
    Abstract: This invention relates to novel compounds of formula (I). Formula (I) in which the variable groups are as defined in the specification and claims, to pharmaceutical compositions containing them, and to a method of treatment using them for treatment of cancer.
    Type: Application
    Filed: November 2, 2006
    Publication date: December 1, 2011
    Applicant: BAYER HEALTHCARE AG
    Inventors: Stephen O'Connor, Jacques Dumas, Wendy Lee, Julie Dixon, David Cantin, David Gunn, Jennifer Burke, Barton Phillips, Derek Lowe, Tatiana Shelekhin, Gan Wang, Xin Ma, Shihong Ying, Andrea McClure, Furahi Achebe, Mario Lobell, Frederick Ehrgott, Christiana Iwuagwu, Kyle Parcella
  • Preparation and use of aryl alkyl acid derivatives for the treatment of obesity
    Patent number: 8013166
    Abstract: This invention relates to certain aryl alkyl acid compounds, compositions, and methods for treating or preventing obesity and related diseases.
    Type: Grant
    Filed: September 5, 2008
    Date of Patent: September 6, 2011
    Assignee: Bayer Healthcare LLC
    Inventors: Roger A. Smith, Ann-Marie Campbell, Philip Coish, Miao Dai, Susan Jenkins, Derek Lowe, Stephen J. O'Connor, Ning Su, Gan Wang, Mingbao Zhang, Lei Zhu
  • Preparation and use of aryl alkyl acid derivatives for the treatment of obesity
    Patent number: 7968576
    Abstract: This invention relates to certain aryl alkyl acid compounds, compositions, and methods for treating or preventing obesity and related diseases.
    Type: Grant
    Filed: September 8, 2008
    Date of Patent: June 28, 2011
    Inventors: Roger A. Smith, Ann-Marie Campbell, Philip Coish, Miao Dai, Susan Jenkins, Derek Lowe, Stephen J. O'Connor, Ning Su, Gan Wang, Mingbao Zhang, Lei Zhu
  • PREPARATION AND USE OF BIPHENYL-4-YL-CARBONYLAMINO ACID DERIVATIVES FOR THE TREATMENT OF OBESITY
    Publication number: 20110118302
    Abstract: This invention relates to certain biphenyl-4-yl carbonylamino acid compounds, compositions, and methods for treating or preventing obesity and related diseases.
    Type: Application
    Filed: July 14, 2010
    Publication date: May 19, 2011
    Applicant: Bayer Pharmaceuticals Corporation
    Inventors: Roger Smith, Stephen J. O'Connor, Philip Coish, Derek Lowe, Roger B. Clark, Jeffrey Stebbins, Ann-Marie Campbell, Christiana Akuche, Tatiana Shelekhin
  • PREPARATION AND USE OF BIPHENYL AMINO ACID DERIVATIVES FOR THE TREATMENT OF OBESITY
    Publication number: 20100234307
    Abstract: This invention relates to certain biphenyl amino acid compounds, compositions, and methods for treating or preventing obesity and related diseases.
    Type: Application
    Filed: May 6, 2010
    Publication date: September 16, 2010
    Applicant: Bayer HealthCare LLC
    Inventors: Roger A. Smith, Derek Lowe, Tatiana Shelekhin, Georgiy Bondar, Philip Coish, Stephen J. O'Connor
  • Preparation and use of biphenyl-4-yl-carbonylamino acid derivatives for the treatment of obesity
    Patent number: 7759376
    Abstract: This invention relates to certain biphenyl-4-yl carbonylamino acid compounds, compositions, and methods for treating or preventing obesity and related diseases.
    Type: Grant
    Filed: October 14, 2005
    Date of Patent: July 20, 2010
    Assignee: Bayer Healthcare LLC
    Inventors: Roger Smith, Stephen J. O'Connor, Philip Coish, Derek Lowe, Roger B. Clark, Jeffrey Stebbins, Ann-Marie Campbell, Christiana Akuche, Tatiana Shelekhin
  • Preparation and Use of Biphenyl Amino Acid Derivatives for the Treatment of Obesity
    Publication number: 20100016295
    Abstract: This invention relates to certain biphenyl amino acid compounds, compositions, and methods for treating or preventing obesity and related diseases.
    Type: Application
    Filed: July 31, 2006
    Publication date: January 21, 2010
    Applicant: Bayer Healthcare LLC
    Inventors: Roger A. Smith, Derek Lowe, Tatiana Shelekhin, Georgiy Bondar, Philip Coish, Stephen J. O'Connor
  • Preparation and use of aryl alkyl acid derivatives for the treatment of obesity
    Publication number: 20090270468
    Abstract: This invention relates to certain aryl alkyl acid compounds, compositions, and methods for treating or preventing obesity and related diseases.
    Type: Application
    Filed: September 5, 2008
    Publication date: October 29, 2009
    Inventors: Roger Smith, Ann-Marie Campbell, Philip Coish, Miao Dai, Susan Jenkins, Derek Lowe, Stephen O'Connor, Ning Su, Gan Wang, Minghao Zhang, Lei Zhu
  • PREPARATION AND USE OF ARYL ALKYL ACID DERIVATIVES FOR THE TREATMENT OF OBESITY
    Publication number: 20090253762
    Abstract: This invention relates to certain aryl alkyl acid compounds, compositions, and methods for treating or preventing obesity and related diseases.
    Type: Application
    Filed: September 8, 2008
    Publication date: October 8, 2009
    Inventors: Roger Smith, Ann-Marie Campbell, Philip Coish, Miao Dai, Susan Jenkins, Derek Lowe, Stephen O'Connor, Ning Su, Gan Wang, Mingbao Zhang, Lei Zhu
  • LOW TOXICITY FUEL AND LUBRICANT FOR TWO-STROKE ENGINES
    Publication number: 20090223117
    Abstract: A low toxicity fuel and lubricant for two-stroke engines includes a fuel component that is based on ethanol and includes 2-25% volatile hydrocarbon fractions, and a lubricant component based on an oil that is soluble in ethanol, for example castor oil.
    Type: Application
    Filed: December 7, 2005
    Publication date: September 10, 2009
    Inventor: Derek Lowe
  • Preparation and Use of Aryl Alkyl Acid Derivatives for the Treatment of Obesity
    Publication number: 20090215780
    Abstract: This invention relates to certain aryl alkyl acid compounds, compositions, and methods for treating or preventing obesity and related diseases.
    Type: Application
    Filed: April 18, 2006
    Publication date: August 27, 2009
    Applicant: Bayer Pharmaceuticals Corporation
    Inventors: Roger Smith, Derek Lowe, Philip Coish, Ann-Marie Campbell, Gan Wang, Manoj Patel, Gerogiy Bondar
  • PREPARATION AND USE OF ARYL ALKYL ACID DERIVATIVES FOR THE TREATMENT OF OBESITY
    Publication number: 20090197795
    Abstract: This invention relates to certain aryl alkyl acid compounds, compositions, and methods for treating or preventing obesity and related diseases.
    Type: Application
    Filed: August 4, 2008
    Publication date: August 6, 2009
    Applicant: Bayer HealthCare LLC
    Inventors: Roger Smith, Ann-Marie Campbell, Philip Coish, Miao Dai, Susan Jenkins, Derek Lowe, Stephen O'Connor, Ning Su, Gan Wang, Mingbao Zhang, Lei Zhu
  • Preparation and use of aryl alkyl acid derivatives for the treatment of obesity
    Patent number: 7423156
    Abstract: This invention relates to certain aryl alkyl acid compounds, compositions, and methods for treating or preventing obesity and related diseases.
    Type: Grant
    Filed: January 27, 2006
    Date of Patent: September 9, 2008
    Assignee: Bayer Pharmaceuticals Corporation
    Inventors: Roger Smith, Ann-Marie Campbell, Philip Coish, Miao Dai, Susan Jenkins, Derek Lowe, Stephen O'Connor, Ning Su, Gan Wang, Mingbao Zhang, Lei Zhu
  • Preparation and Use of Biphenyl-4-Yl-Carbonylamino Acid Derivatives for the Treatment of Obesity
    Publication number: 20070265298
    Abstract: This invention relates to certain biphenyl-4-yl carbonylamino acid compounds, compositions, and methods for treating or preventing obesity and related diseases.
    Type: Application
    Filed: October 14, 2005
    Publication date: November 15, 2007
    Applicant: Bayer Pharmaceuticals corporation
    Inventors: Roger Smith, Stephen O'Connor, Philip Coish, Derek Lowe, Roger Clark, Jeffrey Stebbins, Ann-Marie Campbell, Christiana Akuche, Tatiana Shelekhin
  • Indane acetic acid derivatives and their use as pharmaceutical agents, intermediates, and method of preparation
    Publication number: 20060205723
    Abstract: This invention relates to novel indane acetic acid derivatives which are useful in the treatment of diseases such as diabetes, obesity, hyperlipidemia, and atherosclerotic diseases. The invention also relates to intermediates useful in preparation of indane acetic derivatives and to methods of preparation.
    Type: Application
    Filed: May 5, 2006
    Publication date: September 14, 2006
    Applicant: Bayer Pharmaceuticals Corporation
    Inventors: Derek Lowe, Philip Wickens, Xin Ma, Mingbao Zhang, William Bullock, Philip Coish, Ingo Mugge, Andreas Stolle, Ming Wang, Yamin Wang, Chengzhi Zhang, Hai-Jun Zhang, Lei Zhu, Manami Tsutsumi, James Livingston
  • Preparation and use of aryl alkyl acid derivatives for the treatment of obesity
    Publication number: 20060194859
    Abstract: This invention relates to certain aryl alkyl acid compounds, compositions, and methods for treating or preventing obesity and related diseases.
    Type: Application
    Filed: January 27, 2006
    Publication date: August 31, 2006
    Applicant: Bayer Pharmaceuticals Corporation
    Inventors: Roger Smith, Ann-Marie Campbell, Philip Coish, Miao Dai, Susan Jenkins, Derek Lowe, Stephen O'Connor, Ning Su, Gan Wang, Mingbao Zhang, Lei Zhu
  • Preparation and use of aryl alkyl acid derivatives for the treatment of obesity
    Patent number: 7091228
    Abstract: This invention relates to certain aryl alkyl acid compounds, compositions, and methods for treating or preventing obesity and related diseases.
    Type: Grant
    Filed: May 6, 2004
    Date of Patent: August 15, 2006
    Assignee: Bayer Pharmaceuticals Corporation
    Inventors: Roger Smith, Ann-Marie Campbell, Philip Coish, Miao Dai, Susan Jenkins, Derek Lowe, Stephen O'Connor, Ning Su, Gan Wang, Mingbao Zhang, Lei Zhu
  • Hydroxamic acids useful in the treatment of hyper-proliferative disorders
    Publication number: 20060063760
    Abstract: This invention relates to a compound of Formula (I) and its use in treating hyper-proliferative disorders.
    Type: Application
    Filed: April 16, 2004
    Publication date: March 23, 2006
    Applicant: BAYER PHARMACEUTICALS CORPORATION
    Inventors: Yamin Wang, Maio Dai, Holia Hatoum-Mokdad, Zhengqiu Hong, Harold Kluender, Gaetan Ladouceur, Tindy Li, Derek Lowe, Eric Mull, Tatiana Shelekhin, Roger Smith, Wai Wong
  • 2,6-Substituted chroman derivatives useful as beta-3 adrenoreceptor agonists
    Publication number: 20050215594
    Abstract: This invention relates to novel 2,6-substituted chroman derivatives which are useful in the treatment of beta-3 adrenoreceptor-mediated conditions.
    Type: Application
    Filed: April 28, 2005
    Publication date: September 29, 2005
    Applicant: Bayer Pharmaceuticals Corporation
    Inventors: Stephen O'Connor, Gaetan Ladouceur, William Bullock, Ann-Marie Campbell, Miao Dai, Robert Dally, Jacques Dumas, Holia Hatoum-Mokdad, Uday Khire, Wendy Lee, Qingjie Liu, Derek Lowe, Steven Magnuson, Ning Qi, Tatiana Skelekhin, Quanrong Shen, Roger Smith, Ming Wang