Abstract: Halogenated analogs of 5-aza-2?-deoxycytidine, such as halogenated analogs of 5-aza-4?-thio-2?-deoxycytidine (5-aza-T-dCyd) are described. Pharmaceutical compositions including a halogenated analog and methods of using the halogenated analogs to inhibit neoplasia are described.

Abstract: Halogenated analogs of 5-aza-2?-deoxycytidine, such as halogenated analogs of 5-aza-4?-thio-2?-deoxycytidine (5-aza-T-dCyd) are described. Pharmaceutical compositions including a halogenated analog and methods of using the halogenated analogs to inhibit neoplasia are described.

Abstract: Example implementations relate to printers for printing a printing liquid on a medium, the printer having a media path for the medium; the media path comprising a print platen for receiving the medium from an input media carrier and for outputting the medium to an output media carrier; the media path also comprising a spread roller disposed between the print platen and the output media roller, and the print platen having an associated arcuate surface for orientating the medium towards the spread roller.

Abstract: A data processing system includes: a processor; a data interface for communication with a control unit, the processor being on one side of the data interface; internal storage accessible by the processor, the internal storage being on the same side of the data interface as the processor; and a register array accessible by the processor and comprising a plurality of registers, each register having a plurality of vector lanes. The storage is arranged to store control data indicating an ordered selection of vector lanes of one or more of the registers. The processor is arranged to, in response to receiving instruction data from a control unit, perform a swizzle operation in which data is selected from one or more source registers in the register array, and transferred to a destination register. The data is selected from vector lanes in accordance with control data stored in the internal storage.

Abstract: An optical sensor device (10) includes an application module (12) for applying an irregular pattern of marks to a surface of a medium and an optical detector module (14). The optical detector module (14) acquires images of the applied marks and may determine an advancement speed of the medium based on the acquired images.

Abstract: Halogenated analogs of 5-aza-2?-deoxycytidine, such as halogenated analogs of 5-aza-4?-thio-2?-deoxycytidine (5-aza-T-dCyd) are described. Pharmaceutical compositions including a halogenated analog and methods of using the halogenated analogs to inhibit neoplasia are described.

Abstract: A printer carriage comprises a sensor to be actuated when an actuation member coupled to the sensor contacts a raised portion in a printing target. A vertical position of the actuation member may be adjusted with respect to the printer carriage.

Abstract: In an example, a printhead carriage to be used in a printing system is disclosed herewith wherein the carriage includes a pocket defined by a first wall and a second wall opposite to the first wall; a set of electrical connectors provided on the first wall; and a mechanical protector. In an example, the mechanical protector may be a sheet with a determined length that extends from the first wall into the pocket and a width that extends along the width of the first wall over the electrical connectors. In an example, the mechanical protector includes an elastic member biased towards the second wall.

Abstract: It is disclosed a print-head carriage comprising base and a tab with a rotatable connection to the base on a first end, the rotation of the tab defining a closed position in which a second end opposite to the first end is in contact with the base and an open position in which the second end is separated from the base, the base being adapted to receive a print-head along an insertion direction when the tab is in the open position wherein the tab further comprises a latch located at a position remote to the rotatable connection comprising a lever, that separates from the tab in an unlocked position and moves towards the tab in a locked position; wherein the latch comprises a biasing mechanism to bias the latch to the locked position.

Abstract: A printer carriage comprises a sensor to be actuated when an actuation member coupled to the sensor contacts a raised portion in a printing target. A vertical position of the actuation member may be adjusted with respect to the printer carriage.

Abstract: Methods for stereoselective synthesis and manufacturing of 2?-deoxynucleosides, such as 2?-ribonucleosides, are disclosed. In some embodiments, the 2?-deoxynucleoside is a ?-anomer of a 2?-deoxynucleoside having a 3? ? hydroxyl, 4? ? hydroxymethyl configuration. Nonlimiting examples of compounds prepared by the disclosed methods include 4?-thio-2?-deoxycytidine (T-dCyd) and 5-aza-4?-thio-2?-deoxycytidine (5-aza-T-dCyd; aza-T-dCyd; aza-T-dC).

Abstract: A method, a system and computer program products for securely enabling in-network functionality over encrypted data sessions, the method involving establishing an encrypted data session between a client communication application (100) and a server communication application (200) over a communication network; receiving and/or transmitting, by the client communication application (100), in the established encrypted data session, at least one encrypted communication data (D) from/to the server communication application (200) through a computing network element (M); and performing, by the computing network element (M), different actions other than data packet forwarding from one communication application to the other on the encrypted communication data (D). The encrypted communication data (D) has a plurality of data portions, or contexts, (CTX), each encrypted by a context key, and the different actions being specific for the computing network element (M) and for one or more of the contexts (CTX_X).

Abstract: A data processing system includes: a processor; a data interface for communication with a control unit, the processor being on one side of the data interface; internal storage accessible by the processor, the internal storage being on the same side of the data interface as the processor; and a register array accessible by the processor and comprising a plurality of registers, each register having a plurality of vector lanes. The storage is arranged to store control data indicating an ordered selection of vector lanes of one or more of the registers. The processor is arranged to, in response to receiving instruction data from a control unit, perform a swizzle operation in which data is selected from one or more source registers in the register array, and transferred to a destination register. The data is selected from vector lanes in accordance with control data stored in the internal storage.

Abstract: An apparatus (100) for a large format printer (400) to support a spindle (102) of a roll of media comprises at least one supporting member (104, 104a, 104b, 104c) to support the weight of the spindle (102) when the spindle is loaded into the apparatus (100). The apparatus also comprises a cradle (108) to support the spindle (102) as it is loaded onto or unloaded from the at least one supporting member (104). The cradle (108) is moveable between a first position to receive the spindle (102) and a second position when the spindle is supported by the at least one supporting member (104). The apparatus also comprises a shock absorbing member (110) in contact with the cradle (108). The cradle moves between the first and second positions as the spindle (102) is loaded into the apparatus (100) and the shock absorbing member (110) absorbs kinetic energy of the cradle (108) as it moves from the first position to the second position.

Abstract: It is disclosed a print-head carriage comprising base and a tab with a rotatable connection to the base on a first end, the rotation of the tab defining a closed position in which a second end opposite to the first end is in contact with the base and an open position in which the second end is separated from the base, the base being adapted to receive a print-head along an insertion direction when the tab is in the open position wherein the tab further comprises a latch located at a position remote to the rotatable connection comprising a lever, that separates from the tab in an unlocked position and moves towards the tab in a locked position; wherein the latch comprises a biasing mechanism to bias the latch to the locked position.

Abstract: In an example, a printhead carriage to be used in a printing system is disclosed herewith wherein the carriage includes a pocket defined by a first wall and a second wall opposite to the first wall; a set of electrical connectors provided on the first wall; and a mechanical protector. In an example, the mechanical protector may be a sheet with a determined length that extends from the first wall into the pocket and a width that extends along the width of the first wall over the electrical connectors. In an example, the mechanical protector includes an elastic member biased towards the second wall.

Abstract: A method, a system and computer program products for securely enabling in-network functionality over encrypted data sessions, the method involving establishing an encrypted data session between a client communication application (100) and a server communication application (200) over a communication network; receiving and/or transmitting, by the client communication application (100), in the established encrypted data session, at least one encrypted communication data (D) from/to the server communication application (200) through a computing network element (M); and performing, by the computing network element (M), different actions other than data packet forwarding from one communication application to the other on the encrypted communication data (D). The encrypted communication data (D) has a plurality of data portions, or contexts, (CTX), each encrypted by a context key, and the different actions being specific for the computing network element (M) and for one or more of the contexts (CTX_X).

Abstract: A printer comprises a printing assembly for printing an image on a print media in a print zone; a cutting assembly for cutting the print media along a contour in a cut zone; wherein the print zone and the cut zone are distinct from one another, one of the zones being downstream of the respective other zone in a print media advance direction; a control unit controlling the printhead assembly and the cutting assembly to perform printing and cutting operations during a single print media feed. A method of printing, using said printer, comprises feeding the print media through the cut zone and through the print zone, in any order; and simultaneously printing an image and cutting a contour while the print media is being fed through the cut zone and through the print zone.

Abstract: An apparatus (100) for a large format printer (400) to support a spindle (102) of a roll of media comprises at least one supporting member (104, 104a, 104b, 104c) to support the weight of the spindle (102) when the spindle is loaded into the apparatus (100). The apparatus also comprises a cradle (108) to support the spindle (102) as it is loaded onto or unloaded from the at least one supporting member (104). The cradle (108) is moveable between a first position to receive the spindle (102) and a second position when the spindle is supported by the at least one supporting member (104). The apparatus also comprises a shock absorbing member (110) in contact with the cradle (108). The cradle moves between the first and second positions as the spindle (102) is loaded into the apparatus (100) and the shock absorbing member (110) absorbs kinetic energy of the cradle (108) as it moves from the first position to the second position.

Abstract: A printer comprises a printing assembly for printing an image on a print media in a print zone; a cutting assembly for cutting the print media along a contour in a cut zone; wherein the print zone and the cut zone are distinct from one another, one of the zones being downstream of the respective other zone in a print media advance direction; a control unit controlling the printhead assembly and the cutting assembly to perform printing and cutting operations during a single print media feed. A method of printing, using said printer, comprises feeding the print media through the cut zone and through the print zone, in any order; and simultaneously printing an image and cutting a contour while the print media is being fed through the cut zone and through the print zone.