Patents by Inventor Dieter Hochrainer
Dieter Hochrainer has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
-
Patent number: 6988496Abstract: For meteredly dispensing a liquid over a period of several months from a container which can be stored over a long period of time, the need is for a container which is practically diffusion-tight and in which the liquid does not come into contact with the ambient atmosphere. The cartridge according to the invention is a three-shell container comprising a collapsible bag which contains the liquid, a container which is stable in respect of shape and a stiff metal casing. The cartridge can be releasably connected to a dispensing device. The cartridge can be provided with a micro-opening with which the time for pressure equalisation between the cartridge and the ambient atmosphere can be adjusted. The cartridge is suitable for aqueous and for alcoholic liquids which contain a pharmacologically active substance. The liquid in the cartridge is protected from external influences. The cartridge can be used in an atomiser for producing an inhalable aerosol for the treatment of illnesses.Type: GrantFiled: February 23, 2000Date of Patent: January 24, 2006Assignee: Boehringer Ingelheim International GmbHInventors: Joachim Eicher, Johannes Geser, Matthias Hausmann, Michael Schyra, Gilbert Wuttke, Andreas Fiol, Heinrich Kladders, Dieter Hochrainer, Bernd Zierenberg
-
Patent number: 6986346Abstract: The invention relates to an apparatus comprising a closure-cap and a container in the form of a two-chamber cartridge in which an active ingredient and a solvent can be stored separately until the apparatus is used in a nebuliser, as well as an active substance concentrate in which the active substance is present as a solution or suspension for storage purposes.Type: GrantFiled: September 27, 2002Date of Patent: January 17, 2006Assignee: Boehringer Ingelheim Pharma KGInventors: Dieter Hochrainer, Bernd Zierenberg
-
Publication number: 20050263151Abstract: The invention relates to a powder inhaler (1) with mouthpiece (2) for dispersing pharmaceutical medicament formulations, which comprises an auxiliary energy source in the form of a pressure medium system (3), having a device for supplying (6) a powder formulation (7), while on activation of the pressure medium system a gaseous pressure medium (8) released by the pressure medium system (3) forms an aerosol (9) with the powder formulation (7) such that the powder particles are present in the gaseous pressure medium (8) in dispersed form. This is achieved by means of a powder inhaler (1) comprising a multi-channel nozzle, the channels of which are inclined to one another at an angle such that the aerosol jets flowing through them meet one another downstream behind the nozzle (10).Type: ApplicationFiled: March 4, 2005Publication date: December 1, 2005Applicant: Boehringer Ingelheim International GmbHInventors: Dieter Hochrainer, Stephen Dunne, Georg Boeck, Joerg Schiewe
-
Publication number: 20050241634Abstract: A cartridge having two chambers for separate storage of active substance and solvent.Type: ApplicationFiled: July 11, 2005Publication date: November 3, 2005Inventor: Dieter Hochrainer
-
Publication number: 20050241635Abstract: A cartridge for propellant-free administration of a liquid pharmaceutical composition by inhalation includes: an elongate displacing device including an upper end and a lower end, the lower end for at least partial insertion into a container; a cartridge chamber disposed at the lower end of the displacing device and operable store a pharmaceutical formulation, the cartridge chamber including at least one pierceably sealed opening; and a cannula guide extending from the upper end of the displacing device to the cartridge chamber, wherein insertion of a cannula through the guide pierces the sealed opening and releases the pharmaceutical formulation into a liquid solvent in the container to form the liquid pharmaceutical composition.Type: ApplicationFiled: July 11, 2005Publication date: November 3, 2005Inventor: Dieter Hochrainer
-
Publication number: 20050211364Abstract: A method of sealing parts of a plastic capsule by forming a weld seam in an overlapping region of the parts of the capsule, wherein the capsule comprises a capsule cap having an open end and a capsule body having an open end, the method comprising: (a) holding the capsule cap and the capsule body in a capsule holder comprising a first holding part and a second holding part which can be guided synchronously with one another, wherein the first holding part interlockingly surrounds the capsule cap and the second holding part interlockingly surrounds the capsule body; (b) closing the capsule holder holding the capsule cap and the capsule body so that the open end of the capsule cap and the open end of the capsule body form a sealed cavity therebetween and form an overlapping region, wherein the overlapping region is not covered by the capsule holder, to obtain a closed capsule; and (c) welding the closed capsule using an energy beam of hot gas or laser light on the overlapping region by forming the weld seam therType: ApplicationFiled: April 8, 2005Publication date: September 29, 2005Applicant: Boehringer Ingelheim Pharma KGInventors: Dieter Hochrainer, Herbert Wachtel
-
Patent number: 6949154Abstract: A method of sealing parts of a plastic capsule by forming a weld seam in an overlapping region of the parts of the capsule, wherein the capsule comprises a capsule cap having an open end and a capsule body having an open end, the method comprising: (a) holding the capsule cap and the capsule body in a capsule holder comprising a first holding part and a second holding part which can be guided synchronously with one another, wherein the first holding part interlockingly surrounds the capsule cap and the second holding part interlockingly surrounds the capsule body; (b) closing the capsule holder holding the capsule cap and the capsule body so that the open end of the capsule cap and the open end of the capsule body form a sealed cavity therebetween and form an overlapping region, wherein the overlapping region is not covered by the capsule holder, to obtain a closed capsule; and (c) welding the closed capsule using an energy beam of hot gas or laser light on the overlapping region by forming the weld seam tType: GrantFiled: July 23, 2002Date of Patent: September 27, 2005Assignee: Boehringer Ingelheim Pharma KGInventors: Dieter Hochrainer, Herbert Wachtel
-
Publication number: 20050159441Abstract: The invention relates to an apparatus comprising a closure-cap and a container in the form of a two-chamber cartridge in which an active ingredient and a solvent can be stored separately until the apparatus is used in a nebuliser, as well as an active substance concentrate in which the active-substance is present as a solution or suspension for storage purposes.Type: ApplicationFiled: March 11, 2005Publication date: July 21, 2005Inventors: Dieter Hochrainer, Bernd Zierenberg
-
Publication number: 20050084457Abstract: The invention relates to capsules for inhalation (inhalettes) made from specific capsule materials with a reduced moisture content, which contain the active substance tiotropium in the form of powdered preparations and are characterised by increased stability.Type: ApplicationFiled: July 29, 2004Publication date: April 21, 2005Applicant: Boehringer Ingelheim Pharma KGInventors: Dieter Hochrainer, Karoline Bechtold-Peters, Michael Trunk, Michael Walz
-
Publication number: 20050077392Abstract: The invention relates to a nozzle system for a delivery device for liquids, wherein the nozzle system comprises a nozzle and a device which fixes the nozzle in the delivery device. The delivery device, an atomiser, has a liquid reservoir from which a liquid is forced through the nozzle under pressure. The nozzle fixing means may itself be secured by a second fixing, e.g., in the form of a check nut, or the fixing may itself be a check nut. According to the invention the fixing means on the nozzle outlet side has a specific geometry which minimises the proportion of dispensed liquid deposited on the fixing means. Preferably, the present invention is part of a propellant-free device for nebulising pharmaceutical liquids.Type: ApplicationFiled: November 5, 2004Publication date: April 14, 2005Applicant: Boehringer Ingelheim International GmbHInventors: Johannes Geser, Dieter Hochrainer, Herbert Wachtel, Stephen Dunne
-
Publication number: 20040187868Abstract: The invention pertains to a dry powder inhaler (1) with a mouthpiece (2) for dispersing pharmaceutical drug formulations, which has available an auxiliary energy source in the form of a pressure medium system (3), with a device for provisioning (6) of a powder formulation (7), whereby upon activation of the pressure medium system a gaseous pressure medium (8) released by the pressure medium system (3) forms with the powder formulation (7) an aerosol (9) in such a way that the powder particles are present in dispersed form within the gaseous pressure medium (8).Type: ApplicationFiled: September 24, 2003Publication date: September 30, 2004Applicant: Boehringer Ingelheim Pharma GmbH & Co. KGInventors: Dieter Hochrainer, Joerg Schiewe, Bernd Zierenberg, Stephen Dunne
-
Publication number: 20040182867Abstract: For medical fluids, two-part containers are used which consist of an inner container and an outer container which is impenetrable to diffusion. The inner container collapses when the fluid is removed.Type: ApplicationFiled: April 1, 2004Publication date: September 23, 2004Applicant: Boehringer Ingelheim International GmbHInventors: Dieter Hochrainer, Bernd Zierenberg, Heinrich Kladders, Martin Essing, Gilbert Wuttke, Matthias Hausmann, Joachim Eicher
-
Publication number: 20040164099Abstract: The present invention relates to atomizers for administering preservative-free liquids to the cornea or conjunctiva of the eye, with special eye adapters for atomizers and the use of atomizers for ophthalmological administration. The atomizers according to the invention are free from propellant gas.Type: ApplicationFiled: December 18, 2003Publication date: August 26, 2004Applicant: Boehringer Ingelheim Pharma GmbH & Co., KGInventors: Michael Diestelhorst, Isolde Martin, Bernd Zierenberg, Dieter Hochrainer
-
Publication number: 20040159322Abstract: The invention relates to a novel capsule for receiving an active substance to be administered by inhalation, which is preferably intended for use in a powder inhaler operating on the Bernoulli principle.Type: ApplicationFiled: January 14, 2004Publication date: August 19, 2004Applicant: Boehringer Ingelheim International GmbHInventors: Heinrich Kladders, Burkhard Metzger, Dieter Hochrainer
-
Publication number: 20040149283Abstract: The invention relates to a powder inhaler operating on the Bernoulli principle with replaceable cylindrical disposable capsules as the active substance reservoir. The powder inhaler consists essentially of a preferably cylindrical capsule chamber provided with means for laterally opening the capsule, an air inlet opening in the capsule chamber and an air outlet opening and a mouthpiece mounted downstream of the air outlet opening. The capsule chamber is constructed so that after insertion the reservoir capsule can essentially only move in the longitudinal direction when a sufficiently powerful air stream passes through the capsule chamber, guided substantially parallel to the longitudinal axis of the capsule. According to the invention, the inner wall of the capsule chamber is uneven in order to achieve a better emptying of the capsule than is obtained with a smooth inner surface.Type: ApplicationFiled: December 4, 2003Publication date: August 5, 2004Applicant: Boehringer Ingelheim Pharma GmbH & Co. KGInventor: Dieter Hochrainer
-
Publication number: 20040143235Abstract: Foil bags are used as a primary packaging for liquids, the bags permitting the liquid to be taken therefrom without the application of a considerable amount of force. A container is provided for a medicinal liquid, the container being gas-tight and liquid-tight so that it is storable over many months. The container includes a collapsible foil bag on which a flange, which is stable in respect of shape, is disposed. The flange is designed for fitting onto a discharge connection member. The container can be disposed in a casing which is stable in respect of shape. The medicinal liquid does not come into contact with air and is protected from the effect of light. The medicinal liquid may be dispensed from the foil bag in many partial quantities over a prolonged period of time, with a respective partial amount thereof being converted into an aerosol by means of an atomizer.Type: ApplicationFiled: January 12, 2004Publication date: July 22, 2004Applicant: Boehringer Ingelheim GmbHInventors: Bernhard Freund, Dieter Hochrainer, Heinrich Kladders, Bernd Zierenberg, Joachim Eicher, Johannes Geser, Martin Essing, Holger Reinecke
-
Publication number: 20040131668Abstract: The present invention relates to capsules for holding pharmaceutical preparations for powder inhalers with increased drug safety and capsules for pharmaceutical preparations for powder inhalers with improved adaptation to their use in powder inhalers. The capsules consist of water-insoluble hydrophobic synthetic materials which do not significantly affect the pharmaceutical quality of the contents themselves, but which improve the usability of the filled capsules with regard to their function, their longevity and/or the geographic location of their use, and are advantageous at various stages from manufacture up to utilisation.Type: ApplicationFiled: December 18, 2003Publication date: July 8, 2004Applicant: Boehringer Ingelheim Pharma KGInventors: Dieter Hochrainer, Josef Eckert
-
Publication number: 20040045548Abstract: The invention relates to a two-chamber cartridge for drug formulations for propellant-free inhalers.Type: ApplicationFiled: August 11, 2003Publication date: March 11, 2004Applicant: Boehringer Ingelheim KGInventor: Dieter Hochrainer
-
Patent number: 6685691Abstract: Foil bags are used as a primary packaging for liquids, the bags permitting the liquid to be taken therefrom without the application of a considerable amount of force. A container is provided for a medicinal liquid, the container being gas-tight and liquid-tight so that it is storable over many months. The container includes a collapsible foil bag on which a flange, which is stable in respect of shape, is disposed. The flange is designed for fitting onto a discharge connection member. The container can be disposed in a casing which is stable in respect of shape. The medicinal liquid does not come into contact with air and is protected from the effect of light. The medicinal liquid may be dispensed from the foil bag in many partial quantities over a prolonged period of time, with a respective partial amount thereof being converted into an aerosol by means of an atomizer.Type: GrantFiled: February 26, 1999Date of Patent: February 3, 2004Assignee: Boehringer Ingelheim GmbHInventors: Bernhard Freund, Dieter Hochrainer, Heinrich Kladders, Bernd Zierenberg, Joachim Eicher, Johannes Geser, Martin Essing, Holger Reinecke
-
Publication number: 20040010239Abstract: The present invention relates to atomizers for administering liquids to the cornea or conjunctiva of the eye, special eye adapters for atomizers and the use of atomizers for ophthalmological administration. The atomizers according to the invention are free from propellant gas and have an energy reservoir for supplying the energy needed for the atomization process.Type: ApplicationFiled: June 23, 2003Publication date: January 15, 2004Applicant: Boehringer Ingelheim Pharma KGInventors: Dieter Hochrainer, Bernd Zierenberg, Michael Diestelhorst, Isolde Martin