Patents by Inventor DiZhong Chen

DiZhong Chen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Heterocyclic compounds
    Patent number: 8143282
    Abstract: The present invention relates to compounds which are inhibitors of histone deacetylase. More particularly, the present invention relates to heterocyclic compounds and methods for their preparation. These compounds may be useful as medicaments for the treatment of proliferative disorders as well as other diseases involving, relating to or associated with enzymes having histone deacetylase (HDAC) activities.
    Type: Grant
    Filed: August 1, 2006
    Date of Patent: March 27, 2012
    Assignee: S*BIO Pte Ltd.
    Inventors: Dizhong Chen, Weiping Deng, Ken C. Lee, Pek L. Lye, Eric T. Sun, Haishan Wang, Niefang Yu
  • 2-MORPHOLINYLPURINES AS INHIBITORS OF PI3K
    Publication number: 20110009403
    Abstract: The present invention relates to purine compounds that are useful as kinase inhibitors. More particularly, the present invention relates to purine compounds, methods for their preparation, pharmaceutical compositions containing these compounds and uses of these compounds in the treatment of proliferative disorders. These compounds may be useful as medicaments for the treatment of a number of proliferative disorders including tumours and cancers as well as other disorders or conditions related to or associated with mTOR kinases.
    Type: Application
    Filed: October 3, 2008
    Publication date: January 13, 2011
    Applicant: S*BIO Pte Ltd.
    Inventors: Harish Kumar Mysore Nagaraj, DiZhong Chen, Anders Poulsen, Meredith Williams
  • BENZIMIDAZOLE DERIVATIVES: PREPARATION AND PHARMACEUTICAL APPLICATIONS
    Publication number: 20100256138
    Abstract: The present invention relates to hydroxamate compounds which are inhibitors of histone deacetylase. More particularly, the present invention relates to benzimidazole containing compounds and methods for their preparation. These compounds may be useful as medicaments for the treatment of proliferative disorders as well as other diseases involving, relating to or associated with dysregulation of histone deacetylase (HDAC).
    Type: Application
    Filed: June 14, 2010
    Publication date: October 7, 2010
    Applicant: S*BIO Pte Ltd.
    Inventors: Dizhong Chen, Hong Y. Song, Eric T. Sun, Niefang Yu, Yong Zou
  • Benzimidazole derivatives: preparation and pharmaceutical applications
    Patent number: 7781595
    Abstract: The present invention relates to hydroxamate compounds which are inhibitors of histone deacetylase. More particularly, the present invention relates to benzimidazole containing compounds and methods for their preparation. These compounds may be useful as medicaments for the treatment of proliferative disorders as well as other diseases involving, relating to or associated with dysregulation of histone deacetylase (HDAC).
    Type: Grant
    Filed: September 21, 2004
    Date of Patent: August 24, 2010
    Assignee: S*BIO Pte Ltd.
    Inventors: DiZhong Chen, Hong Yan Song, Eric T. Sun, Niefang Yu, Yong Zou
  • Heterocyclic Compounds
    Publication number: 20090048300
    Abstract: The present invention relates to compounds which are inhibitors of histone deacetylase. More particularly, the present invention relates to heterocyclic compounds and methods for their preparation. These compounds may be useful as medicaments for the treatment of proliferative disorders as well as other diseases involving, relating to or associated with enzymes having histone deacetylase (HDAC) activities.
    Type: Application
    Filed: August 1, 2006
    Publication date: February 19, 2009
    Applicant: S*BIO Pte Ltd.
    Inventors: Dizhong Chen, Weiping Deng, Ken C. Lee, Pek L. Lye, Eric T. Sun, Haishan Wang, Niefang Yu
  • Benzimidazole derivates: preparation and pharmaceutical applications
    Publication number: 20070043043
    Abstract: The present invention relates to hydroxamate compounds which are inhibitors of histone deacetylase. More particularly, the present invention relates to benzimidazole containing compounds and methods for their preparation. These compounds may be useful as medicaments for the treatment of proliferative disorders as well as other diseases involving, relating to or associated with dysregulation of histone deacetylase (HDAC).
    Type: Application
    Filed: September 21, 2004
    Publication date: February 22, 2007
    Applicant: S*BIO Pte Ltd.
    Inventors: Dizhong Chen, Weiping Deng, Kanda Sangthongpitag, Hong Song, Eric Sun, Niefang Yu, Yong Zou