Patents by Inventor Donald Burke

Donald Burke has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Systematic evolution of ligands by exponential enrichment: chimeric selex
    Patent number: 5637459
    Abstract: Methods are disclosed for producing chimeric nucleic acid molecules with two or more functions. A chimeric library is generated in which individual chimeric molecules combine the functions or characteristics of two or more parent libraries, each parent library having been selected through the SELEX procedure for a specific function or feature. The chimeric molecules of this invention are useful in a variety of ways, including having improved affinities for a target molecule, enhancing assembly of multi-component molecules, and promoting reactions between two molecules.
    Type: Grant
    Filed: August 2, 1994
    Date of Patent: June 10, 1997
    Assignee: NeXstar Pharmaceuticals, Inc.
    Inventors: Donald Burke, Ted Tarasow, Bruce E. Eaton, Larry Gold