Patents by Inventor Donald J. Kyle

Donald J. Kyle has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Treatment and prevention of sleep disorders
    Patent number: 12370191
    Abstract: The disclosure relates to methods for treating or preventing a sleep disorder by administering a compound of Formula (1)(1), or a compound of formula (1A), (1B), (1C), (1D), (1E), or (1F) to an animal in need of such treatment. In certain embodiments, such compounds effectively treat or prevent a sleep disorder in the animal, while producing reduced side effects compared to previously available compounds.
    Type: Grant
    Filed: June 28, 2023
    Date of Patent: July 29, 2025
    Assignee: Purdue Pharma L.P.
    Inventors: Stephen C. Harris, Ram P. Kapil, Donald J. Kyle, Garth Whiteside
  • SLEEP DISORDER TREATMENT AND PREVENTION
    Publication number: 20250134886
    Abstract: The disclosure relates to methods for treating or preventing an Insomnia Disorder by administering to a human in need thereof a compound of formula (I), or a compound of formula (IA), (IB), or (IC), or a solvate thereof, in a daily dose of from about 0.5 mg to about 6.0 mg. In certain embodiments, such compounds effectively treat or prevent an Insomnia Disorder in the animal, while producing reduced side effects compared to previously available compounds.
    Type: Application
    Filed: November 13, 2024
    Publication date: May 1, 2025
    Applicant: Purdue Pharma L.P.
    Inventors: Stephen C. HARRIS, Ram P. KAPIL, Donald J. KYLE, Garth WHITESIDE
  • DEVICE FOR VAGINAL OR RECTAL CRYOTHERAPY, AND METHODS OF PRODUCTION AND USE
    Publication number: 20250049491
    Abstract: An insert, and methods of production and use, for vaginal or rectal cryotherapy to relieve chronic pelvic pain, inflammation, edema, pain related to pelvic floor muscle cramping and spasms, vaginal pain, bladder pain, rectal pain, and other pain and symptoms.
    Type: Application
    Filed: August 7, 2024
    Publication date: February 13, 2025
    Inventors: Barbara Ann Dodson, Alfredo Salazar, Jane S. Salazar, Donald J. Kyle
  • Sleep disorder treatment and prevention
    Patent number: 12171762
    Abstract: The disclosure relates to methods for treating or preventing an Insomnia Disorder by administering to a human in need thereof a compound of formula (I), or a compound of formula (IA), (IB), or (IC), or a solvate thereof, in a daily dose of from about 0.5 mg to about 6.0 mg. In certain embodiments, such compounds effectively treat or prevent an Insomnia Disorder in the animal, while producing reduced side effects compared to previously available compounds.
    Type: Grant
    Filed: January 10, 2023
    Date of Patent: December 24, 2024
    Assignee: Purdue Pharma L.P.
    Inventors: Stephen C. Harris, Ram P. Kapil, Donald J. Kyle, Garth Whiteside
  • Systems and Methods for Treating an Opioid-Induced Adverse Pharmacodynamic Response
    Publication number: 20240350479
    Abstract: Disclosed in certain embodiments is a method of treating or preventing an opioid-induced adverse pharmacodynamic response comprising administering to a patient in need thereof an effective amount of buprenorphine.
    Type: Application
    Filed: February 8, 2024
    Publication date: October 24, 2024
    Inventors: Michele Hummel, Donald J. Kyle, Garth Whiteside
  • TREATMENT AND PREVENTION OF SLEEP DISORDERS
    Publication number: 20240058333
    Abstract: The disclosure relates to methods for treating or preventing a sleep disorder by administering a compound of Formula (1)(1), or a compound of formula (1A), (1B), (1C), (1D), (1E), or (1F) to an animal in need of such treatment. In certain embodiments, such compounds effectively treat or prevent a sleep disorder in the animal, while producing reduced side effects compared to previously available compounds.
    Type: Application
    Filed: June 28, 2023
    Publication date: February 22, 2024
    Applicant: Purdue Pharma L.P.
    Inventors: Stephen C. HARRIS, Ram P. KAPIL, Donald J. KYLE, Garth WHITESIDE
  • SLEEP DISORDER TREATMENT AND PREVENTION
    Publication number: 20230293516
    Abstract: The disclosure relates to methods for treating or preventing an Insomnia Disorder by administering to a human in need thereof a compound of formula (I), or a compound of formula (IA), (IB), or (IC), or a solvate thereof, in a daily dose of from about 0.5 mg to about 6.0 mg. In certain embodiments, such compounds effectively treat or prevent an Insomnia Disorder in the animal, while producing reduced side effects compared to previously available compounds.
    Type: Application
    Filed: January 10, 2023
    Publication date: September 21, 2023
    Applicant: Purdue Pharma L.P.
    Inventors: Stephen C. HARRIS, Ram P. KAPIL, Donald J. KYLE, Garth WHITESIDE
  • Treatment and prevention of sleep disorders
    Patent number: 11738023
    Abstract: The disclosure relates to methods for treating or preventing a sleep disorder by administering a compound of formula (1)(1), or a compound of formula (1A), (1B), (1C), (1D), (1E), or (1F) to an animal in need of such treatment. In certain embodiments, such compounds effectively treat or prevent a sleep disorder in the animal, while producing reduced side effects compared to previously available compounds.
    Type: Grant
    Filed: March 8, 2021
    Date of Patent: August 29, 2023
    Assignee: Purdue Pharma L.P.
    Inventors: Stephen C. Harris, Ram P. Kapil, Donald J. Kyle, Garth Whiteside
  • Sleep disorder treatment and prevention
    Patent number: 11576913
    Abstract: The disclosure relates to methods for treating or preventing an Insomnia Disorder by administering to a human in need thereof a compound of formula (I), or a compound of formula (IA), (IB), or (IC), or a solvate thereof, in a daily dose of from about 0.5 mg to about 6.0 mg. In certain embodiments, such compounds effectively treat or prevent an Insomnia Disorder in the animal, while producing reduced side effects compared to previously available compounds.
    Type: Grant
    Filed: January 22, 2019
    Date of Patent: February 14, 2023
    Assignee: Purdue Pharma L.P.
    Inventors: Stephen C. Harris, Ram P. Kapil, Donald J. Kyle, Garth Whiteside
  • TRACE AMINE ASSOCIATED RECEPTOR 1 AGONISTS AND PARTIAL AGONISTS FOR PAIN TREATMENT
    Publication number: 20220280527
    Abstract: This application relates to using trace amine associated receptor 1 (TAARI) agonists and/or partial agonists for treating or preventing pain, especially neuropathic pain.
    Type: Application
    Filed: January 5, 2022
    Publication date: September 8, 2022
    Applicant: Purdue Pharma L.P.
    Inventors: Michele HUMMEL, Donald J. KYLE, Laykea TAFESSE, Garth WHITESIDE
  • Process for preparing oxycodone hydrochloride having less than 25 ppm 14-hydroxycodeinone
    Patent number: 11236098
    Abstract: In certain embodiments the invention is directed to a process for preparing an oxycodone hydrochloride composition having less than 25 ppm of 14-hydroxycodeinone.
    Type: Grant
    Filed: March 15, 2021
    Date of Patent: February 1, 2022
    Assignee: Purdue Pharma L.P.
    Inventors: Robert Chapman, Lonn S. Rider, Qi Hong, Robert Kupper, Donald J. Kyle
  • TREATMENT AND PREVENTION OF SLEEP DISORDERS
    Publication number: 20210330994
    Abstract: The disclosure relates to methods for treating or preventing a sleep disorder by administering a compound of formula (1)(1), or a compound of formula (1A), (1B), (1C), (1D), (1E), or (1F) to an animal in need of such treatment. In certain embodiments, such compounds effectively treat or prevent a sleep disorder in the animal, while producing reduced side effects compared to previously available compounds.
    Type: Application
    Filed: March 8, 2021
    Publication date: October 28, 2021
    Applicant: Purdue Pharma L.P.
    Inventors: Stephen C. HARRIS, Ram P. KAPIL, Donald J. KYLE, Garth WHITESIDE
  • PROCESS FOR PREPARING OXYCODONE HYDROCHLORIDE HAVING LESS THAN 25 PPM 14-HYDROXYCODEINONE
    Publication number: 20210198268
    Abstract: In certain embodiments the invention is directed to a process for preparing an oxycodone hydrochloride composition having less than 25 ppm of 14-hydroxycodeinone.
    Type: Application
    Filed: March 15, 2021
    Publication date: July 1, 2021
    Applicants: Purdue Pharma L.P., Purdue Pharmaceuticals L.P., Rhodes Technologies
    Inventors: Robert CHAPMAN, Lonn S. RIDER, Qi HONG, Robert KUPPER, Donald J. KYLE
  • Systems and Methods for Treating an Opioid-Induced Adverse Pharmacodynamic Response
    Publication number: 20210196706
    Abstract: Disclosed in certain embodiments is a method of treating or preventing an opioid-induced adverse pharmacodynamic response comprising administering to a patient in need thereof an effective amount of buprenorphine.
    Type: Application
    Filed: March 16, 2021
    Publication date: July 1, 2021
    Inventors: Michele Hummel, Donald J. Kyle, Garth Whiteside
  • Treatment and prevention of sleep disorders
    Patent number: 10974081
    Abstract: The disclosure relates to methods for treating or preventing a sleep disorder by administering a compound of formula (1)(1), or a compound of formula (1A), (1B), (1C), (1D), (1E), or (1F) to an animal in need of such treatment. In certain embodiments, such compounds effectively treat or prevent a sleep disorder in the animal, while producing reduced side effects compared to previously available compounds.
    Type: Grant
    Filed: July 25, 2017
    Date of Patent: April 13, 2021
    Assignee: Purdue Pharma L.P.
    Inventors: Stephen C. Harris, Ram P. Kapil, Donald J. Kyle, Garth Whiteside
  • SLEEP DISORDER TREATMENT AND PREVENTION
    Publication number: 20200345726
    Abstract: The disclosure relates to methods for treating or preventing an Insomnia Disorder by administering to a human in need thereof a compound of formula (I), or a compound of formula (IA), (IB), or (IC), or a solvate thereof, in a daily dose of from about 0.5 mg to about 6.0 mg. In certain embodiments, such compounds effectively treat or prevent an Insomnia Disorder in the animal, while producing reduced side effects compared to previously available compounds.
    Type: Application
    Filed: January 22, 2019
    Publication date: November 5, 2020
    Applicant: Purdue Pharma L.P.
    Inventors: Stephen C. HARRIS, Ram P. KAPIL, Donald J. KYLE, Garth WHITESIDE
  • SYSTEMS AND METHODS FOR ATTENUATING OPIOID-INDUCED EUPHORIA
    Publication number: 20200276187
    Abstract: Disclosed in certain embodiments is a method of attenuating or preventing opioid-induced euphoria comprising administering to a patient in need thereof an effective amount of buprenorphine.
    Type: Application
    Filed: March 24, 2020
    Publication date: September 3, 2020
    Applicant: Purdue Pharma L.P.
    Inventors: Michele Hummel, Donald J. Kyle, Garth Whiteside
  • Systems and Methods for Treating an Opioid-Induced Adverse Pharmacodynamic Response
    Publication number: 20200155542
    Abstract: Disclosed in certain embodiments is a method of treating or preventing an opioid-induced adverse pharmacodynamic response comprising administering to a patient in need thereof an effective amount of buprenorphine.
    Type: Application
    Filed: July 31, 2019
    Publication date: May 21, 2020
    Inventors: Michele Hummel, Donald J. Kyle, Garth Whiteside
  • TREATMENT AND PREVENTION OF SLEEP DISORDERS
    Publication number: 20190282836
    Abstract: The disclosure relates to methods for treating or preventing a sleep disorder by administering a compound of formula (1)(1), or a compound of formula (1A), (1B), (1C), (1D), (1E), or (1F) to an animal in need of such treatment. In certain embodiments, such compounds effectively treat or prevent a sleep disorder in the animal, while producing reduced side effects compared to previously available compounds.
    Type: Application
    Filed: July 25, 2017
    Publication date: September 19, 2019
    Inventors: Stephen C. HARRIS, Ram P. KAPIL, Donald J. KYLE, Garth WHITESIDE
  • Systems and methods for treating an opioid-induced adverse pharmacodynamic response
    Patent number: 10398690
    Abstract: Disclosed in certain embodiments is a method of treating or preventing an opioid-induced adverse pharmacodynamic response comprising administering to a patient in need thereof an effective amount of buprenorphine.
    Type: Grant
    Filed: December 18, 2017
    Date of Patent: September 3, 2019
    Assignee: Purdue Pharma L.P.
    Inventors: Michele Hummel, Donald J. Kyle, Garth Whiteside