Patents by Inventor Donald Karanewsky

Donald Karanewsky has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMPOUNDS USEFUL AS MODULATORS OF TRPM8
    Publication number: 20150376136
    Abstract: The present invention includes compounds useful as modulators of TRPM8, such as compounds of Formulae (Ia), (Ib) and (Ic), and the subgenus and species thereof; personal products containing those compounds; and the use of those compounds and the personal products, particularly the use of increasing or inducing chemesthetic sensations, such as cooling or cold sensations.
    Type: Application
    Filed: February 19, 2014
    Publication date: December 31, 2015
    Inventors: Lyudmyla Chumakova, Andrew Patron, Chad Priest, Donald Karanewsky, Rachel Kimmich, Brant Clayton Boren, Jeffrey Robert Hammaker, Volodymyr Chumakov, Wen Zhao, Alain Noncovich, Jane Ung
  • Sweet flavor modifier
    Patent number: 9138013
    Abstract: The present invention includes compounds having structural formula (I), or salts or solvates thereof. These compounds are useful as sweet flavor modifiers. The present invention also includes compositions comprising the present compounds and methods of modulating the sweet taste of compositions.
    Type: Grant
    Filed: August 1, 2014
    Date of Patent: September 22, 2015
    Assignee: Senomyx, Inc.
    Inventors: Catherine Tachdjian, Donald Karanewsky, Sara Werner, Vincent Darmohusodo, Jeff Yamamoto
  • SWEET FLAVOR MODIFIER
    Publication number: 20150257422
    Abstract: The present invention includes compounds having structural formula (I), or salts or solvates thereof. These compounds are useful as sweet flavor modifiers. The present invention also includes compositions comprising the present compounds and methods of enhancing the sweet taste of compositions.
    Type: Application
    Filed: March 26, 2015
    Publication date: September 17, 2015
    Inventors: Sara Adamski-Werner, Vincent Darmohusodo, Catherine Tachdjian, Donald Karanewsky
  • METHOD OF IMPROVING STABILITY OF SWEET ENHANCER AND COMPOSITION CONTAINING STABILIZED SWEET ENHANCER
    Publication number: 20150245642
    Abstract: The present invention includes methods of stabilizing one or more sweet enhancers when they are exposed to a light source as well as liquid compositions containing one or more sweet enhancers and one or more photostabilizers.
    Type: Application
    Filed: March 26, 2015
    Publication date: September 3, 2015
    Inventors: Catherine Tachdjian, Donald Karanewsky, Xiao Qing Tang, Hanghui Liu
  • SWEET FLAVOR MODIFIER
    Publication number: 20150031684
    Abstract: The present invention includes compounds having structural formula (I), or salts or solvates thereof. These compounds are useful as sweet flavor modifiers. The present invention also includes compositions comprising the present compounds and methods of modulating the sweet taste of compositions.
    Type: Application
    Filed: August 1, 2014
    Publication date: January 29, 2015
    Inventors: Catherine TACHDJIAN, Donald KARANEWSKY, Sara WERNER, Vincent DARMOHUSODO, Jeff YAMAMOTO
  • Sweet flavor modifier
    Patent number: 8877922
    Abstract: The present invention includes compounds having structural formula (I): or salts or solvates thereof. These compounds are useful as sweet flavor modifiers. The present invention also includes compositions comprising the present compounds and methods of modulating the sweet taste of compositions.
    Type: Grant
    Filed: December 4, 2013
    Date of Patent: November 4, 2014
    Assignee: Senomyx, Inc.
    Inventors: Catherine Tachdjian, Donald Karanewsky, Sara Werner, Vincent Darmohusodo, Jeff Yamamoto
  • SWEET FLAVOR MODIFIER
    Publication number: 20140094453
    Abstract: The present invention includes compounds having structural formula (I), or salts or solvates thereof. These compounds are useful as sweet flavor modifiers. The present invention also includes compositions comprising the present compounds and methods of modulating the sweet taste of compositions.
    Type: Application
    Filed: December 4, 2013
    Publication date: April 3, 2014
    Inventors: Catherine TACHDJIAN, Donald KARANEWSKY, Sara WERNER, Vincent DARMOHUSODO, Jeff YAMAMOTO
  • 2,4-PYRIMIDINEDIAMINES USEFUL IN THE TREATMENT OF NEOPLASTIC DISEASES, INFLAMMATORY AND IMMUNE SYSTEM DISORDERS
    Publication number: 20110098280
    Abstract: Novel pyrimidine derivatives of formula I to processes for their production, their use as pharmaceuticals and to pharmaceutical compositions comprising them.
    Type: Application
    Filed: January 4, 2011
    Publication date: April 28, 2011
    Applicants: Novartis AG, IRM LLC
    Inventors: Carlos Garcia-Echeverria, Takanori Kanazawa, Eiji Kawahara, Keiichi Masuya, Naoko Matsuura, Takahiro Miyake, Osamu Ohmori, Ichiro Umemura, Ruo Steensma, Greg Chopiuk, Jiqing Jiang, Yongqin Wan, Qiang Ding, Qiong Zhang, Nathanael Schiander Gray, Donald Karanewsky
  • 2, 4-pyrimidinediamines useful in the treatment of neoplastic diseases, inflammatory and immune system disorders
    Patent number: 7893074
    Abstract: Novel pyrimidine derivatives of formula I to processes for their production, their use as pharmaceuticals and to pharmaceutical compositions comprising them.
    Type: Grant
    Filed: August 13, 2004
    Date of Patent: February 22, 2011
    Assignees: Novartis AG, IRM LLC
    Inventors: Carlos Garcia-Echeverria, Takanori Kanazawa, Eiji Kawahara, Keiichi Masuya, Naoko Matsuura, Takahiro Miyake, Osamu Ohmori, Ichiro Umemura, Ruo Steensma, Greg Chopiuk, Jiqing Jiang, Yongqin Wan, Qiang Ding, Qiong Zhang, Nathanael Schiander Gray, Donald Karanewsky
  • COMPOUNDS AND COMPOSITIONS AS ITPKB INHIBITORS
    Publication number: 20090306039
    Abstract: The invention provides a novel class of compounds, pharmaceutical compositions comprising such compounds and methods of using such compounds to treat or prevent diseases or disorders associated with abnormal or deregulated B cell activities, particularly diseases or disorders that involve aberrant activation of inositol 1,4,5-trisphosphate 3-kinase B (ITPKb).
    Type: Application
    Filed: July 20, 2007
    Publication date: December 10, 2009
    Inventors: Shifeng Pan, Yi Liu, Yun Feng Xie, Dai Cheng, yongqin Wan, Dong Han, Yang Yang, Wenqi Gao, Jiqing Jiang, Badry Bursulaya, Philip Chamberlain, Donald Karanewsky, Xia Wang
  • Glucocorticoid Receptor Modulator Compounds and Methods
    Publication number: 20090105292
    Abstract: Disclosed herein are compounds of Formula I: and pharmaceutically acceptable salts, esters, amides, and prodrugs thereof. Certain of such compounds are selective glucocorticoid receptor modulators and/or selective glucocorticoid binding agents. Also disclosed are methods of making and using such compounds, including, but not limited to, using such compounds for treating various conditions.
    Type: Application
    Filed: February 24, 2005
    Publication date: April 23, 2009
    Applicant: LIGAND PHARMACEUTICALS INCORPORATED
    Inventors: Lin Zhi, Robert Ardecky, Dean Phillips, John Tyhonas, Donald Karanewsky, Robert Higuchi, A.R. Hudson, S.L. Roach, A.C. Vassar, Yongkai Li, Mark Adams, L.J. Valdez, C. Cuervo
  • Tricyclic quinolinone and tricyclic quinoline androgen receptor modulator compounds and methods
    Publication number: 20080300241
    Abstract: Non-steroidal tricyclic quinolinone and tricyclic quinoline compounds and compositions that are agonists, partial agonists and/or antagonists for androgen receptors (AR), their preparation and their uses are described.
    Type: Application
    Filed: November 17, 2006
    Publication date: December 4, 2008
    Inventors: Robert Higuchi, Lin Zhi, Donald Karanewsky, Anthony Thompson, Thomas Caferro, Neelakandha Mani, Jyun-Hung Chen, Marquis Cummings, James Edwards, Mark Adams, Charlotte Deckhut
  • 2, 4-Pyrimidinediamines Useful In The Treatment Of Neoplastic Diseases, Inflammatory And Immune System Disorders
    Publication number: 20080132504
    Abstract: Novel pyrimidine derivatives of formula I to processes for their production, their use as pharmaceuticals and to pharmaceutical compositions comprising them
    Type: Application
    Filed: August 13, 2004
    Publication date: June 5, 2008
    Inventors: Carlos Garcia-Echeverria, Takanori Kanazawa, Eiji Kawahara, Keiichi Masuya, Naoko Matsuura, Takahiro Miyake, Osamu Ohmori, Ichiro Umemura, Ruo Steensma, Greg Chopiuk, Jiqing Jiang, Yongqin Wan, Qiang Ding, Qiong Zhang, Nathanael Schiander Gray, Donald Karanewsky
  • INHIBITORS OF CATHEPSIN S
    Publication number: 20080108595
    Abstract: The present invention provides compounds, compositions and methods for the selective inhibition of cathepsin S. In a preferred aspect, cathepsin S is selectively inhibited in the presence of at least one other cathepsin isozyme. The present invention also provides methods for treating a disease state in a subject by selectively inhibiting cathepsin S.
    Type: Application
    Filed: October 31, 2007
    Publication date: May 8, 2008
    Applicant: IRM LLC
    Inventors: Hong Liu, Arnab Chatterjee, David Tully, Phillip Alper, Badry Bursulaya, Jianhua Guo, David Woodmansee, Daniel Mutnick, Donald Karanewsky, Yun He
  • INHIBITORS OF CATHEPSIN S
    Publication number: 20080021025
    Abstract: The present invention provides compounds, compositions and methods for the selective inhibition of cathepsin S. In a preferred aspect, cathepsin S is selectively inhibited in the presence of at least one other cathepsin isozyme. The present invention also provides methods for treating a disease state in a subject by selectively inhibiting cathepsin S.
    Type: Application
    Filed: August 20, 2007
    Publication date: January 24, 2008
    Inventors: Hong Liu, Phillip Alper, Daniel Muthick, Donald Karanewsky
  • Inhibitors of cathepsin S
    Patent number: 7297714
    Abstract: The present invention provides compounds, compositions and methods for the selective inhibition of cathepsin S. In a preferred aspect, cathepsin S is selectively inhibited in the presence of at least one other cathepsin isozyme. The present invention also provides methods for treating a disease state in a subject by selectively inhibiting cathepsin S.
    Type: Grant
    Filed: October 20, 2004
    Date of Patent: November 20, 2007
    Assignee: IRM LLC
    Inventors: Hong Liu, Phillip Alper, Daniel Mutnick, Donald Karanewsky
  • INHIBITORS OF CATHEPSIN S
    Publication number: 20070259873
    Abstract: The present invention provides compounds, compositions and methods for the selective inhibition of cathepsin S. In a preferred aspect, cathepsin S is selectively inhibited in the presence of at least one other cathepsin isozyme. The present invention also provides methods for treating a disease state in a subject by selectively inhibiting cathepsin S.
    Type: Application
    Filed: July 13, 2007
    Publication date: November 8, 2007
    Applicant: IRM LLC
    Inventors: Hong Liu, Phillip Alper, Donald Karanewsky
  • INTRACELLULAR RECEPTOR MODULATOR COMPOUNDS AND METHODS
    Publication number: 20070254917
    Abstract: This invention relates to compounds that bind to intracellular receptors and/or modulate activity of intracellular receptors, and to methods for making and using such compounds.
    Type: Application
    Filed: January 12, 2007
    Publication date: November 1, 2007
    Inventors: Robert Higuchi, Steven Roach, Lin Zhi, Mark Adams, Yan Liu, Donald Karanewsky, Andrew Hudson
  • MINERALOCORTICOID RECEPTOR MODULATOR COMPOUNDS, PROCESSES FOR THEIR PREPARATION, AND THEIR USES
    Publication number: 20070197520
    Abstract: This invention relates to compounds that bind to mineralocorticoid receptors and/or modulate activity of mineralocorticoid receptors, and to methods for making and using such compounds.
    Type: Application
    Filed: January 12, 2007
    Publication date: August 23, 2007
    Inventors: Robert Higuchi, Lin Zhi, Mark Adams, Yan Liu, Donald Karanewsky
  • MINERALOCORTICOID RECEPTOR MODULATOR COMPOUNDS AND METHODS, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THESE COMPOUNDS
    Publication number: 20070185102
    Abstract: This invention relates to compounds that bind to mineralocorticoid receptors and/or modulate activity of mineralocorticoid receptors, and to methods for making and using such compounds.
    Type: Application
    Filed: January 12, 2007
    Publication date: August 9, 2007
    Inventors: Robert Higuchi, Lin Zhi, Donald Karanewsky