Patents by Inventor Donald L. Wise

Donald L. Wise has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 5429822
    Abstract: A biodegradable polymeric multiphasic release system of one or more biodegradable bursting units capable of delivering biologically active substances in a burst or pulse at predetermined times and a method for constructing those units is disclosed. The individual bursting units of the system may take the form of a biodegradable, membrane coated capsule surrounding a core material which may include an active agent. The membrane ruptures after a predetermined time upon exposure to water or bodily, or other aqueous environmental fluids. The bursting units may be used in any situation in which a controlled pulsed release of an active substance is desired. The predetermined time release of each bursting unit is controlled by the composition of the core material, the initial radius and wall thickness of the membrane and the porosity of the membrane.
    Type: Grant
    Filed: March 13, 1992
    Date of Patent: July 4, 1995
    Assignee: Cambridge Scientific, Inc.
    Inventors: Joseph D. Gresser, Donald L. Wise, Abdul G. Jimoh, Don C. Augenstein, Dean O. Kuethe, Debra J. Trantolo
  • Patent number: 5352423
    Abstract: A method is disclosed for removing pollutants from the exhaust of combustion systems burning fuels containing substantial amounts of sulfur and nitrogen. An exemplary method of the invention involves the formation and reaction of a sorbent comprising calcium benzoate. The calcium benzoate is either dry-sprayed (in the form of a fine powder) or wet-sprayed in an aqueous solution in a high temperature environment such as a combustion chamber. The latter technique is feasible since calcium benzoate is a water-soluble form of calcium. When the dispersed particles of calcium benzoate are heated to a high temperature, the organic benzoate burns off and fine calcium oxide particles are formed. These particles are cenospheric (hollow) and have thin and highly porous walls, thus, affording optimum external and internal accessibility for reacting with toxic gaseous emissions such as SO.sub.2. Further, the combustion of the organic benzoate portion of the sorbent results in the conversion of NO.sub.x to N.sub.2.
    Type: Grant
    Filed: March 30, 1993
    Date of Patent: October 4, 1994
    Assignee: Northeastern University
    Inventors: Yiannis A. Levendis, Donald L. Wise
  • Patent number: 5312605
    Abstract: A method is disclosed for removing pollutants from the exhaust of combustion systems burning fuels containing substantial amounts of sulfur and nitrogen. An exemplary method of the invention involves the formation and reaction of a sorbent comprising calcium magnesium acetate (CMA). The CMA is either dry-sprayed (in the form of a fine powder) or wet-sprayed in an aqueous solution in a high temperature environment such as a combustion chamber. The latter technique is feasible since CMA is a uniquely water-soluble form of calcium and magnesium. When the dispersed particles of CMA are heated to a high temperature, fine calcium and magnesium oxide particles, which are hollow with thin and highly porous walls are formed, affording optimum external and internal accessibility for reacting with toxic gaseous emissions such as SO.sub.2. Further, the combustion of the organic acetate portion of the sorbent results in the conversion of NO.sub.x to N.sub.2.
    Type: Grant
    Filed: December 11, 1991
    Date of Patent: May 17, 1994
    Assignee: Northeastern University
    Inventors: Yiannis A. Levendis, Donald L. Wise
  • Patent number: 5254465
    Abstract: A process for the manufacture of alkaline earth salts of acetic acid. Biomass is fermented under appropriate conditions to produce acetic acid, which is extracted from the fermentation broth with the aid of a basic liquid ion exchanger dissolved in an organic phase. The organic phase containing the product acetic acid is then reacted directly with a basic material such as limestone, and the resulting alkaline earth acetate product is recovered from the aqueous phase.
    Type: Grant
    Filed: October 1, 1991
    Date of Patent: October 19, 1993
    Assignee: Northeastern University
    Inventor: Donald L. Wise
  • Patent number: 5094668
    Abstract: Coal is desulfurized by oxidation to convert organic sulfur moieties in the coal matrix to sulfates, and by treatment with a sulfatase to cleave the sulfates and thereby remove organic sulfur.
    Type: Grant
    Filed: November 22, 1989
    Date of Patent: March 10, 1992
    Assignee: Houston Industries Incorporated
    Inventors: Ernest E. Kern, William M. Menger, David A. Odelson, Anthony S. Sinskey, Donald L. Wise, Debra J. Trantolo
  • Patent number: 5068188
    Abstract: A process for the manufacture of alkaline earth salts of acetic acid. Biomass is fermented under appropriate conditions to produce acetic acid, which is extracted from the fermentation broth with the aid of a basic liquid ion exchanger dissolved in an organic phase. The organic phase containing the product acetic acid is then reacted directly with a basic material such as limestone, and the resulting alkaline earth acetate product is recovered from the aqueous phase.
    Type: Grant
    Filed: June 20, 1989
    Date of Patent: November 26, 1991
    Assignee: Northeastern University
    Inventors: Donald L. Wise, Don C. Augenstein, Joseph D. Gresser
  • Patent number: 4845034
    Abstract: A method for carrying out a biochemical reaction with a culture of microorganisms is performed in a cavity formed in a subterranean formation to produce combustible hydrocarbon gases. The method is especially suitable for the conversion of alkali-oxidized or hydrolyzed coal, such as lignite, to methane. The method may be performed in the cavity as a continuously stirred tank reaction, or plug flow or as a staged reaction. The method may also be done as an anaerobic fixed film process using particles as an anaerobic filter, as a sludge blanket, or as an expanded bed process.
    Type: Grant
    Filed: January 6, 1986
    Date of Patent: July 4, 1989
    Assignee: Houston Industries Incorporated
    Inventors: William M. Menger, Ernest E. Kern, Kermit Allen, O. C. Karkalits, Donald L. Wise, Alfred P. Leuschner
  • Patent number: 4215686
    Abstract: An artificial burn covering comprising a poly(.epsilon.-caprolactone) film with a poly(.epsilon.-caprolactone) fabric attached thereto.
    Type: Grant
    Filed: April 6, 1979
    Date of Patent: August 5, 1980
    Assignee: The United States of America as represented by the Secretary of the Navy
    Inventors: John B. Gregory, Arthur D. Schwope, Donald L. Wise
  • Patent number: 3978203
    Abstract: A novel class of polymer-based products for use in physiological environment, e.g. for use as sutures or implanted, medicine-bearing compositions for use in controlled-rate medication, or the like. The advantageous polymers on which these products are based are condensation polymers formed of Krebs cycle acid-type compounds and a physiologically-tolerable polyol type compound such as glycerol or the like.
    Type: Grant
    Filed: July 12, 1974
    Date of Patent: August 31, 1976
    Assignee: Dynatech Corporation
    Inventor: Donald L. Wise
  • Patent number: 3935308
    Abstract: A preparation and a method are described for emergency, interim treatment extensive burn injuries, e.g., flash burns, to external portions of a person. A solution of the polymer poly-.epsilon.-caprolactone is a volatile solvent, such as acetone or tetrahydrofuran, is applied to the burn area by spraying or swabbing, so that upon evaporation of the solvent a film of the polymer is left to serve as a barrier to insensible water loss.
    Type: Grant
    Filed: August 8, 1974
    Date of Patent: January 27, 1976
    Assignee: The United States of America as represented by the Secretary of the Navy
    Inventors: Donald L. Wise, Arthur D. Schwope, Kenneth W. Sell