Abstract: Flavoring materials may be produced from filamentous fungi by contacting them with water at a temperature sufficient to reduce their nucleic acid content and concentrating or separating solids from the resulting aqueous solution. The materials may be further subjected to a chemical reaction for example with a sulphur containing amino acid.

Abstract: Compositions for generating a cooked flavor in a foodstuff, comprising specified flavor precursors that react on heating to generate the flavor and maintain a reactive association after inclusion in the foodstuff. The compositions may include combination of a sulphur source, e.g. hydrogen sulphide, methane thiol, a sulfur-containing amino acid, thiamine, cystine, sodium sulphide, ammonium sulphide, ammonium polysulphide, onions, garlic, shallots, eggs, methionine, and mixtures thereof, and at least one reductone, e.g. a furanone, a ketone, a pyrone, an aldehyde, a carbonyl compound, isomaltol, maltol, pyruvaldehyde, hydroxyacetone, 3-deoxyglucosone, 5-hydroxy-5,6-dihydromaltol, 2,3-butanedione, 3-hydroxy-2-butanone, a process flavor, cooked vegetable concentrates, soy sauce, and mixtures thereof.

Abstract: Flavouring materials may be produced from filamentous fungi by contacting them with water at a temperature sufficient to reduce their nucleic acid content and concentrating or separating solids from the resulting aqueous solution. The materials may be further subjected to a chemical reaction for example with a sulphur containing amino acid.

Abstract: Flavoring materials may be produced from filamentous fungi by contacting them with water at a temperature sufficient to reduce their nucleic acid content and concentrating or separating solids from the resulting aqueous solution. The materials may be further subjected to a chemical reaction for example with a sulphur containing amino acid.

Abstract: The present invention provides a highly glycosylated iduronate-2-sulfatase enzyme comprising an iduronate-2-sulfatase polypeptide with at least 5 kilodalton (kDa) more sugar than iduronate-2-sulfatase purified from a natural source, e.g. human liver. The present invention also provides an enzymatically active polypeptide fragment or variant of such a highly glycosylated iduronate-2-sulfatase. The present invention further provides an isolated nucleic acid encoding iduronate-2-sulfatase, as well as an expression vector, a host cell and a method for producing the present highly glycosylated iduronate-2-sulfatase enzyme.

Abstract: A transportable building module including structure defining a floor sub-frame (13) and at least one wall structure (16) about a room space. The building module further includes at least one roof sub-module (20). This roof sub-module is hingedly mounted to the wall structure for pivotal movement between an extended position and a retracted transport position, in which retracted transport position the height of the building module is less than when the roof sub-module is in its extended position. In separate aspects, there are disclosed a transportable building with a separate roof module, and a building with a transversely arranged roof module beam.

Abstract: An efficient architecture for an interpolator (100) disposed to process oversampled data is disclosed herein. The interpolator (100) includes an input divider circuit (104) configured to receive an input data word over an input data line. A register (108) is provided for latching the divided input data word from the divider (104). The divided input data word is added within a summer (112) to a latched divided data word from the register, thereby forming a summed data word. A multiplexer (116) produces an interpolated output by multiplexing the summed data word with an input data word. In a preferred implementation, the register (108) is latched at a first clock rate, and the multiplexer (116) is clocked at twice the first clock rate. The efficient filter architecture allows interpolation to be performed in the absence of multipliers, and in a manner using filter coefficients equivalent to powers of two.

Abstract: The present invention relates generally to &agr;-L-iduronidase and to genetic sequences encoding same. More particularly, the present invention provides an isolated nucleic acid molecule comprising a sequence of nucleotides which encodes or are complementary to a sequence which encodes a mammalian &agr;-L-iduronidase or fragment or derivative thereof and to the recombinant enzyme encoded thereby. These molecules are useful in the investigation, diagnosis and treatment of subjects suspected of or suffering from &agr;-L-iduronidase deficiency.

Abstract: The present invention provides a speed governor (5) suitable for use in a fluid driven down-hole tool (3). The speed governor comprises an actuator (7) operatively coupled to a motive fluid flow control valve (6). The actuator is and arranged so as to be activatable, directly or indirectly, in response to the running speed of the tool (3), for opening of the control valve (6) with increasing rotational speed of the motor (3) above a predetermined speed limit thereby to limit the rotational speed of the downhole tool (3).

Abstract: The present invention relates generally to mammalian &agr;-N-acetyglucosaminidase and to genetic sequences encoding same and to their use in the investigation, diagnosis and treatment of subjects suspected of or suffering from &agr;-N-acetylglucosaminidase deficiency.

Abstract: The present invention relates generally to &agr;-L-iduronidase and to genetic sequences encoding same. More particularly, the present invention provides an isolated nucleic acid molecule comprising a sequence of nucleotides which encodes or are complementary to a sequence which encodes a mammalian &agr;-L-iduronidase or fragment or derivative thereof and to the recombinant enzyme encoded thereby. These molecules are useful in the investigation, diagnosis and treatment of subjects suspected of or suffering from &agr;-L-iduronidase deficiency.

Abstract: The present invention provides a highly glycosylated iduronate-2-sulfatase enzyme comprising an iduronate-2-sulfatase polypeptide with at least 5 kilodalton (kDa) more sugar than iduronate-2-sulfatase purified from a natural source, e.g. human liver. The present invention also provides an enzymatically active polypeptide fragment or variant of such a highly glycosylated iduronate-2-sulfatase. The present invention further provides an isolated nucleic acid encoding iduronate-2-sulfatase, as well as an expression vector, a host cell and a method for producing the present highly glycosylated iduronate-2-sulfatase enzyme.

Abstract: The present invention relates generally to .alpha.-L-iduronidase and to genetic sequences encoding same. More particularly, the present invention provides an isolated nucleic acid molecule comprising a sequence of nucleotides which encodes or are complementary to a sequence which encodes a mammalian .alpha.-L-iduronidase or fragment or derivative thereof and to the recombinant enzyme encoded thereby. These molecules are useful in the investigation, diagnosis and treatment of subjects suspected of or suffering from .alpha.-L-iduronidase deficiency.

Abstract: A portable hard disk drive has an electrically erasable programmable read-only-memory (EEPROM) for storing a first password for allowing a user access to the disk and a random access memory (RAM) for temporarily storing a password entered by a user. A microprocessor is arranged to compare the user-entered passed with the password stored in the EEPROM and to generate a signal to allow a user access to the disk if a valid match is found and to prohibit access if there is no match.

Abstract: The present invention provides a highly glycosylated iduronate-2-sulfatase enzyme comprising an iduronate-2-sulfatase polypeptide with at least 5 kilodalton (kDa) more sugar than iduronate-2-sulfatase purified from a natural source, e.g. human liver. The present invention also provides an enzymatically active polypeptide fragment or variant of such a highly glycosylated iduronate-2-sulfatase. The present intention further provides an isolated nucleic acid encoding iduronate-2-sulfatase, as well as an expression vector, a host cell and a method for producing the present highly glycosylated iduronate-2-sulfatase enzyme.

Abstract: The present invention provides a highly glycosylated iduronate-2-sulfatase enzyme comprising an iduronate-2-sulfatase polypeptide with at least 5 kilodalton (kDa) more sugar than iduronate-2-sulfatase purified from a natural source, e.g. human liver. The present invention also provides an enzymatically active polypeptide fragment or variant of such a highly glycosylated iduronate-2-sulfatase. The present invention further provides an isolated nucleic acid encoding iduronate-2-sulfatase, as well as an expression vector, a host cell and a method for producing the present highly glycosylated iduronate-2-sulfatase enzyme.

Abstract: The present invention relates to a miniature hard disk drive system including a substantially sealed enclosure housing a head-disk assembly and a printed circuit board assembly. The head-disk assembly includes a rotary drive motor and an actuator assembly which pivotally supports and positions one or more read-write head flexure assemblies. In one aspect of the invention, the drive system includes two miniature hard disks having an outer diameter of between 40 mm and 50 mm and has a total thickness not exceeding 10.5 mm. In another aspect, the printed circuit board assembly has first contact pads and the head-disk assembly has a flexible circuit assembly with a first flexible portion connected to the actuator assembly for electrical connection to the read-write heads and with a second flexible portion having second contact pads.

Abstract: A tuft carrier loading apparatus for loading individual tufts into tuft-retention sites spaced along an elongate tuft carrier which is guided for longitudinal movement along a path of travel having a plurality of individually selectively operable tuft forming devices. Each tuft forming device is operable to feed an individual tuft to a tuft-retention site on the carrier. The carrier moves along said path of travel intermittently through a series of successive positions where predefined tuft retention sites are moved temporarily into registry with each tuft forming devices. By controlling selection of the tuft forming devices, tufts are fed to selected sites while the carrier is located at each successive position.

Abstract: An electrode plate including an active portion pasted with active material and a plate head including a connection tab. The plate head is constituted by the same metal foam as the plate support, but the density of the metal foam in the plate head is not less than 2.5 times the density of the metal foam in the remainder of the electrode plate, the higher density of the plate head coming from an operation in which the foam of the support is compressed, the tab of the plate head emerging from the middle of the thickness of the plate and being derived from compression of the support in two directions: compression firstly in the direction of its height; and compression secondly in the direction of its thickness. Such an electrode plate is made from a plate of metal foam whose top edge is compressed so as to form the plate head.

Abstract: The present invention provides a highly glycosylated iduronate-2-sulfatase enzyme comprising an iduronate-2-sulfatase polypeptide with at least 5 kilodalton (kDa) more sugar than iduronate-2-sulfatase purified from a natural source, e.g. human liver. The present invention also provides an enzymatically active polypeptide fragment or variant of such a highly glycosylated iduronate-2-sulfatase. The present invention further provides an isolated nucleic acid encoding iduronate-2-sulfatase, as well as an expression vector, a host cell and a method for producing the present highly glycosylated iduronate-2-sulfatase enzyme.