Abstract: The present invention relates to a method for producing animal models of cerebrovascular disease, comprising ligation of the common carotid artery (CCA) and administration of a nitric oxide (NO) inhibitor, animal models of cerebrovascular disease produced thereby, and a method for producing animals having small individual differences in susceptibility to the onset of cerebrovascular disease by using the same. The method for producing animal models of cerebrovascular disease according to the present invention can overcome the conventional problems of complexity and low yield. Particularly, the production method of the present invention can produce animal models of cerebrovascular disease with a high yield by a simple method.

Abstract: In a method of manufacture, a displacement sensor is provided over a conditioner disk. The conditioner disk is rotated to perform a conditioning process on a polishing surface of a polishing pad. A displacement of the rotating conditioner disk is detected using the displacement sensor during the conditioning process. A height of the conditioner disk is calculated from the detected displacement. An end point of the conditioning process is determined on the polishing surface based on the calculated height.

Abstract: In a method of manufacture, a displacement sensor is provided over a conditioner disk. The conditioner disk is rotated to perform a conditioning process on a polishing surface of a polishing pad. A displacement of the rotating conditioner disk is detected using the displacement sensor during the conditioning process. A height of the conditioner disk is calculated from the detected displacement. An end point of the conditioning process is determined on the polishing surface based on the calculated height.

Abstract: In a method of manufacture, a displacement sensor is provided over a conditioner disk. The conditioner disk is rotated to perform a conditioning process on a polishing surface of a polishing pad. A displacement of the rotating conditioner disk is detected using the displacement sensor during the conditioning process. A height of the conditioner disk is calculated from the detected displacement. An end point of the conditioning process is determined on the polishing surface based on the calculated height.

Abstract: An apparatus for image analysis includes: an image acquisition unit for stacking a plurality of two-dimensional image data in a predetermined order; a three-dimensional image generation unit for generating a plurality of three-dimensional data on the basis of different types of multiple items of information for the plurality of two-dimensional image data in a stacked form from the image acquisition unit; and a deep learning algorithm analysis unit for applying a two-dimensional convolutional neural network to each of the plurality of three-dimensional data from the three-dimensional image generation unit, and combining results of applying the two-dimensional convolutional neural network to the plurality of three-dimensional data.

Abstract: An apparatus for image analysis includes: an image acquisition unit for stacking a plurality of two-dimensional image data in a predetermined order; a three-dimensional image generation unit for generating a plurality of three-dimensional data on the basis of different types of multiple items of information for the plurality of two-dimensional image data in a stacked form from the image acquisition unit; and a deep learning algorithm analysis unit for applying a two-dimensional convolutional neural network to each of the plurality of three-dimensional data from the three-dimensional image generation unit, and combining results of applying the two-dimensional convolutional neural network to the plurality of three-dimensional data.

Abstract: A stroke diagnosis and prognosis prediction system includes: an image acquisition unit configured so as to receive a plurality of images including at least a part of a human brain; an image alignment unit for aligning the plurality of images on the basis of a standard brain image; a lesion area detection and mapping unit for respectively detecting lesion areas from the plurality of images, and mapping the detected lesion areas so as to generate one mapping image; a matching and correction unit, which scales a mapping image so as to match the same to the standard brain image and performs image correction on the mapping image; a three-dimensional image generation unit storing the mapping image in a three-dimensional data space, thereby generating a three-dimensional lesion image; and a stroke diagnosis unit for diagnosing a stroke on the basis of the three-dimensional lesion image.

Abstract: A substrate bonding apparatus includes a lower chuck, an upper chuck, an electric actuator on a central portion of the upper chuck, a pressure sensor, and a controller. The lower chuck may support a lower substrate, the upper chuck may face the lower chuck such that a lower surface of the upper chuck faces the upper surface of the lower chuck, and the upper chuck may support an upper substrate. The electric actuator may lower a bonding pin through the upper chuck to apply a pressure to the upper substrate supported on the upper chuck. The pressure sensor may be below the lower substrate supported on the lower chuck. The pressure sensor may sense a lowering pressure applied by the bonding pin to the pressure sensor in real time. The controller may control the lowering pressure applied by the bonding pin.

Abstract: A substrate bonding apparatus includes a lower chuck, an upper chuck, an electric actuator on a central portion of the upper chuck, a pressure sensor, and a controller. The lower chuck may support a lower substrate, the upper chuck may face the lower chuck such that a lower surface of the upper chuck faces the upper surface of the lower chuck, and the upper chuck may support an upper substrate. The electric actuator may lower a bonding pin through the upper chuck to apply a pressure to the upper substrate supported on the upper chuck. The pressure sensor may be below the lower substrate supported on the lower chuck. The pressure sensor may sense a lowering pressure applied by the bonding pin to the pressure sensor in real time. The controller may control the lowering pressure applied by the bonding pin.

Abstract: In a method of manufacture, a displacement sensor is provided over a conditioner disk. The conditioner disk is rotated to perform a conditioning process on a polishing surface of a polishing pad. A displacement of the rotating conditioner disk is detected using the displacement sensor during the conditioning process. A height of the conditioner disk is calculated from the detected displacement. An end point of the conditioning process is determined on the polishing surface based on the calculated height.

Abstract: A stroke diagnosis and prognosis prediction system includes: an image acquisition unit configured so as to receive a plurality of images including at least a part of a human brain; an image alignment unit for aligning the plurality of images on the basis of a standard brain image; a lesion area detection and mapping unit for respectively detecting lesion areas from the plurality of images, and mapping the detected lesion areas so as to generate one mapping image; a matching and correction unit, which scales a mapping image so as to match the same to the standard brain image and performs image correction on the mapping image; a three-dimensional image generation unit storing the mapping image in a three-dimensional data space, thereby generating a three-dimensional lesion image; and a stroke diagnosis unit for diagnosing a stroke on the basis of the three-dimensional lesion image.

Abstract: The present invention relates to a CT contrast agent for detecting a thrombus, comprising fibrin-targeted peptide sequence-conjugated glycol chitosan-gold nanoparticles. The CT contrast agent for detecting a thrombus according to an embodiment of the present invention may allow rapid and repeated acquisition of CT image information related to the size and location of a thrombus in cardio-cerebral vascular thrombosis, and also enables the imaging monitoring of cerebral thrombus.

Abstract: Disclosed herein is an iodine-containing radial-shaped macromolecule suitable for an active ingredient of the computed tomography (CT) contrast medium, a method to prepare the same, and a contrast medium composition including the same. With respect to the iodine-containing radial-shaped macromolecule according to the present invention, the duration of contrast enhancement has been significantly improved in comparison to that of the current small molecular contrast media compounds containing iodine.

Abstract: The present invention relates to a CT contrast agent for detecting a thrombus, comprising fibrin-targeted peptide sequence-conjugated glycol chitosan-gold nanoparticles. The CT contrast agent for detecting a thrombus according to an embodiment of the present invention may allow rapid and repeated acquisition of CT image information related to the size and location of a thrombus in cardio-cerebral vascular thrombosis, and also enables the imaging monitoring of cerebral thrombus.

Abstract: According to an example embodiment, an inkjet head cleaning apparatus that removes ink residue from an inkjet head after a purging operation in a non-contact manner includes a cleaning blade and a drive unit. The cleaning blade is at a distance from a bottom of the inkjet head. The drive unit is configured to move the cleaning blade in a direction parallel to the inkjet head bottom. The cleaning blade includes a flat upper surface parallel to the inkjet head bottom, and an ink film is produced between the flat upper surface of the cleaning blade and the inkjet head bottom. The cleaning blade also includes an elongated groove longitudinally in the upper surface of the cleaning blade.

Abstract: Disclosed herein is an iodine-containing radial-shaped macromolecule suitable for an active ingredient of the computed tomography (CT) contrast medium, a method to prepare the same, and a contrast medium composition including the same. With respect to the iodine-containing radial-shaped macromolecule according to the present invention, the duration of contrast enhancement has been significantly improved in comparison to that of the current small molecular contrast media compounds containing iodine.

Abstract: According to an example embodiment, an inkjet head cleaning apparatus that removes ink residue from an inkjet head after a purging operation in a non-contact manner includes a cleaning blade and a drive unit. The cleaning blade is at a distance from a bottom of the inkjet head. The drive unit is configured to move the cleaning blade in a direction parallel to the inkjet head bottom. The cleaning blade includes a flat upper surface parallel to the inkjet head bottom, and an ink film is produced between the flat upper surface of the cleaning blade and the inkjet head bottom. The cleaning blade also includes an elongated groove longitudinally in the upper surface of the cleaning blade.

Abstract: An apparatus to align a substrate and a print head having a plurality of orifices so as to perform a printing operation by ejecting ink on the substrate comprises a camera unit provided between the substrate and the print head to photograph the plurality of orifices of the print head and the substrate so as to align the print head and the substrate, and a camera moving part to movably support the camera unit and to move the camera unit between the substrate and the print head. Thus, the aligning apparatus has a simple configuration that may be easily installed and may be controlled precisely. The aligning apparatus may also be used with opaque substrates.

Abstract: A gantry apparatus includes a pair of first guides disposed parallely each other, a pair of sliders respectively coupled to the pair of first guides to move together with the first guides; a second guide coupled to the pair of sliders to move along the sliders; a head coupled to the second guide to move together with and along the second guide; and a rotary unit provided between the sliders and the second guide and rotating the second guide with respect to a shaft line, the shaft line being perpendicular to the moving directions of the sliders and the head. The gantry apparatus can adjust a movement of the head in diverse directions.