Abstract: An electroluminescent device and a light-emitting layer and an application thereof. The light-emitting layer comprises at least one nano-crystalline semiconductor material and at least one exciplex; an emission spectrum of the exciplex is at least partially overlapped with an excitation spectrum of the nano-crystalline semiconductor material; and the attenuation life of an excited state of the exciplex is longer than the attenuation life of an excited state of the nano-crystalline semiconductor material.

Abstract: The invention provides compositions and in vivo, ex vivo and in vitro methods for trans-differentiation of or re-programming mammalian cells to functional neurons. In particular, the invention provides methods for engineering non-neuronal cells into neurons, including fully functional human neuronal cells, and methods for engineering non-neuronal cells into neurons, e.g., fully functional human neuronal cells, in the brain to treat a neurodegenerative disease. In alternative embodiments, the invention provides compositions comprising re-differentiated or re-programmed mammalian cells, such as human cells, of the invention. The invention also provides compositions and methods for direct reprogramming of cells to a second phenotype or differentiated phenotype, such as a neuron, including a fully functional human neuronal cell.

Abstract: A display panel is provided by the present disclosure. The display panel includes a plurality of repeatedly arranged display units each having an array of sub-pixels displaying a plurality of colors. In the display panel, a plurality of sub-pixels b displaying a first color are arranged in a first spatial isotropic configuration in the display panel, and a plurality of sub-pixels d displaying a second color are arranged in a second spatial isotropic configuration in the display panel. At least one of the first color and the second color contributes most to display resolution among the plurality of colors.

Abstract: A method to detect chromatin-interacting RNAs in any given state of a cell or tissue by examining global RNA interactions with DNA by deep sequencing. A method to generate a global view of chromatin-RNA interactome by mapping the binding locations on the genome of each detected chromatin interacting RNA.

Abstract: The invention provides products of manufacture for screening for compositions that can modify a cell's gene expression profile, and methods for making and using them. In one embodiment, the invention provides products of manufacture and methods comprising a high content, high throughput screening for a composition (e.g., chemicals, small molecules) that can modify a cell's physiology based on the composition's ability to modify the cell's gene expression signature.

Abstract: A hot pressing apparatus includes a positioning template having a forming region for placing a workpiece, a hot pressing template, a plurality of positioning blocks, and a lifting mechanism. A plurality of holes is formed in the forming region along a periphery of the forming region. The positioning blocks are movably disposed outside the forming region along the periphery of the forming region for positioning the workpiece in the forming region. The hot pressing template is movable between a hot pressing position and a releasing position for hot pressing the workpiece located in the forming region cooperatively with the positioning template when moving to the hot pressing position. The lifting mechanism includes a plurality of pillars movably disposed in the holes respectively and a driving device for driving each pillar to extend out from the corresponding hole so as to lift the workpiece.

Abstract: The invention provides compositions and in vivo, ex vivo and in vitro methods for trans-differentiation of or re-programming mammalian cells to functional neurons. In particular, the invention provides methods for engineering non-neuronal cells into neurons, including fully functional human neuronal cells, and methods for engineering non-neuronal cells into neurons, e.g., fully functional human neuronal cells, in the brain to treat a neurodegenerative disease. In alternative embodiments, the invention provides compositions comprising re-differentiated or re-programmed mammalian cells, such as human cells, of the invention. The invention also provides compositions and methods for direct reprogramming of cells to a second phenotype or differentiated phenotype, such as a neuron, including a fully functional human neuronal cell.

Abstract: A display panel is provided by the present disclosure. The display panel includes a plurality of repeatedly arranged display units each having an array of sub-pixels displaying a plurality of colors. In the display panel, a plurality of sub-pixels b displaying a first color are arranged in a first spatial isotropic configuration in the display panel, and a plurality of sub-pixels d displaying a second color are arranged in a second spatial isotropic configuration in the display panel. At least one of the first color and the second color contributes most to display resolution among the plurality of colors.

Abstract: The present invention discloses a polarizing device, a liquid crystal display device and a manufacturing method thereof. The polarizing device comprises: a first support layer, a polarizing layer used to output linear polarized light, and a conversion layer with phase delay of m/4 wavelength. The m is an odd number larger than zero. The first support layer, the polarizing layer, and the conversion layer are staked sequentially. The angle ? between the optical axis of the conversion layer and the polarization axis of the polarizing layer are n*90°+45°, the n being an integer not less than zero. In this way, the present invention can change the polarization state of the emitted light of the liquid crystal display device without significantly increasing the cost of production, which can protect the human eye.

Abstract: A hot pressing apparatus includes a positioning template having a forming region for placing a workpiece, a hot pressing template, a plurality of positioning blocks, and a lifting mechanism. A plurality of holes is formed in the forming region along a periphery of the forming region. The positioning blocks are movably disposed outside the forming region along the periphery of the forming region for positioning the workpiece in the forming region. The hot pressing template is movable between a hot pressing position and a releasing position for hot pressing the workpiece located in the forming region cooperatively with the positioning template when moving to the hot pressing position. The lifting mechanism includes a plurality of pillars movably disposed in the holes respectively and a driving device for driving each pillar to extend out from the corresponding hole so as to lift the workpiece.

Abstract: An optical component capable of changing polarization light state and a liquid crystal display (LCD) device using the same are provided. The optical component including a transparent substrate and a wavelength compensator is disposed at any position from the outer side of the LCD device to the outside in an output direction of an output light. The wavelength compensator is directly attached to the surface of the substrate to convert an output light of the LCD device from a linearly polarized light into a circularly polarized light or an elliptically polarized light, thereby effectively reducing eye fatigue. The LCD device is provided with such an optical component such that a linearly polarized light emerging from the LCD device is converted into a circularly polarized light or an elliptically polarized light to lessen the eye fatigue.

Abstract: The invention provides products of manufacture for screening for compositions that can modify a cell's gene expression profile, and methods for making and using them. In one embodiment, the invention provides products of manufacture and methods comprising a high content, high throughput screening for a composition (e.g., chemicals, small molecules) that can modify a cell's physiology based on the composition's ability to modify the cell's gene expression signature.

Abstract: The disclosure provides methods and compositions useful for high throughput sequencing of nucleic acid sequences associated with gene expression, nucleic acid-polypeptide interactions, and/or chromosomal interactions.

Abstract: The disclosure provides methods of examining the binding of proteins to DNA across a genome (e.g., the entire genome or a portion thereof, such as one or more chromosomes or a chromosome regions). In particular, the disclosure relates to a method of identifying a regulatory region (e.g., a protein or enhancer region) of genomic DNA to which a protein of interest binds. In one aspect, the disclosure looks at tissue related regulation. In another aspect, the disclosure looks at developmental related regulation. In yet another aspect, the disclosure looks at regulation of expression in a particular disease state or disorder.

Abstract: An optical component capable of changing polarization light state and a liquid crystal display (LCD) device using the same are provided. The optical component including a transparent substrate and a wavelength compensator is disposed at any position from the outer side of the LCD device to the outside in an output direction of an output light. The wavelength compensator is directly attached to the surface of the substrate to convert an output light of the LCD device from a linearly polarized light into a circularly polarized light or an elliptically polarized light, thereby effectively reducing eye fatigue. The LCD device is provided with such an optical component such that a linearly polarized light emerging from the LCD device is converted into a circularly polarized light or an elliptically polarized light to lessen the eye fatigue.

Abstract: The present invention is directed to providing sensitive and accurate assays for gene detection, genome-wide gene expression profiling and alternative splice monitoring with a minimum or absence of target-specific amplification.

Abstract: The disclosure provides methods of examining the binding of proteins to DNA across a genome (e.g., the entire genome or a portion thereof, such as one or more chromosomes or a chromosome regions). In particular, the disclosure relates to a method of identifying a regulatory region (e.g., a protein or enhancer region) of genomic DNA to which a protein of interest binds. In one aspect, the disclosure looks at tissue related regulation. In another aspect, the disclosure looks at developmental related regulation. In yet another aspect, the disclosure looks at regulation of expression in a particular disease state or disorder.

Abstract: The present invention is directed to providing sensitive and accurate assays for gene detection, genome-wide gene expression profiling and alternative splice monitoring wit a minimum or absence of target-specific amplification.

Abstract: The present invention is directed to providing sensitive and accurate assays for gene detection, genome-wide gene expression profiling and alternative splice monitoring with a minimum or absence of target-specific amplification.

Abstract: The present invention is directed to providing sensitive and accurate assays for gene detection, genome-wide gene expression profiling and alternative splice monitoring with a minimum or absence of target-specific amplification.