Patents by Inventor Dong Sik Kim

Dong Sik Kim has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20220416680
    Abstract: The present disclosure relates to an inverter mounting structure having improved ease of assembly and durability, and capable of simplifying the structure of an inverter. According to one aspect of the present invention, provided is an inverter mounting structure comprising: a bracket fixed to an enclosure or a wall surface and forming an inverter accommodation space in which the inverter is accommodated and coupled; and an option case coupled to the outside of the bracket.
    Type: Application
    Filed: April 1, 2020
    Publication date: December 29, 2022
    Inventor: Dong Sik KIM
  • Publication number: 20220289819
    Abstract: A steric epitope of CEACAM1 is disclosed. An anti-CEACAM1 antibody or a fragment thereof, which specifically binds to CEACAM1 is disclosed. A steric epitope of CEACAM1 includes all amino acids in critical positions for specific binding to an anti-CEACAM1 antibody and maintains an appropriate three-dimensional structure, and thus can high affinity for an anti-CEACAM1 antibody. In addition, an antibody, or a fragment thereof, that specifically binds to a steric epitope can effectively suppress CEACAM1-CEACAM1 interaction and CEACAM1-CEACAM6 interaction.
    Type: Application
    Filed: November 7, 2019
    Publication date: September 15, 2022
    Applicants: GREEN CROSS CORPORATION, MOGAM INSTITUTE FOR BIOMEDICAL RESEARCH
    Inventors: Mi-Young OH, Jae-Chul LEE, Hye Young PARK, Hye In YUM, Dong-Sik KIM
  • Publication number: 20220275360
    Abstract: The present invention relates to a novel antibody library and an antibody-screening method using same. Having a human sequence-derived specific VH or VL scaffold, the antibody library according to the present invention exhibits high thermodynamic stability and enjoys the advantages of allowing high soluble expression as well as reversible folding. In addition, the antibody according to the present invention includes a variety of rationally controlled CDRs so as to exhibit high specificity and high affinity to all antigens and thus can be advantageously used for selecting an adequate candidate antibody against a target antigen.
    Type: Application
    Filed: May 31, 2019
    Publication date: September 1, 2022
    Inventors: Dong-Sik KIM, Mi Jung LEE, Mi Young OH, Hye-Ji CHOI, Gil-Jung KIM, Shin A JANG, Ae Rin YOON
  • Patent number: 11401343
    Abstract: The present invention relates to an anti-MSLN antibody and a pharmaceutical composition for cancer treatment comprising same. The anti-MSLN antibody according to the present invention has high affinity and specificity for MSLN and thus can be effectively used in cancer prevention or treatment.
    Type: Grant
    Filed: October 22, 2018
    Date of Patent: August 2, 2022
    Assignees: GREEN CROSS CORPORATION, MOGAM INSTITUTE FOR BIOMEDICAL RESEARCH
    Inventors: Ki Su Kim, Jung Hong Jeong, Dong Sik Kim, Yang Mi Lim, Yong Yea Park, Hyung Kwon Lim, Jong Wha Won
  • Patent number: 11349055
    Abstract: A thermoelectric module that has excellent thermal, electric properties, can realize high joining force between thermoelectric elements and an electrode, and can maintain stable joining even at a high temperature.
    Type: Grant
    Filed: May 3, 2021
    Date of Patent: May 31, 2022
    Assignee: LG CHEM, LTD.
    Inventors: Su Jin Kim, Il Ha Lee, Dong Sik Kim, Byung Kyu Lim, Cheol Hee Park, Ki Hwan Kim
  • Publication number: 20220144932
    Abstract: The present disclosure provides antibodies that specifically bind to human FAM19A5 and compositions comprising such antibodies. In some embodiments, antibodies are de-immunized to reduce immunogenicity in a human subject. In certain embodiments, antibodies have undergone affinity maturation. In some embodiments, the anti-FAM19A5 antibodies can modulate FAM19A5 activity, e.g, inhibit, suppress, reduce, or reverse the onset of reactive gliosis and/or excessive proliferation of reactive astrocytes, utilizing such antibodies. The present disclosure also provides methods for treating disorders, such as central nervous system damage, a degenerative brain disorder, a neuropathic pain, or a cancer, by administering an antibody that specifically binds to human FAM19A5.
    Type: Application
    Filed: December 31, 2019
    Publication date: May 12, 2022
    Applicant: NEURACLE SCIENCE CO., LTD.
    Inventors: Bongcheol KIM, Wonkyum KIM, Dong Sik KIM, Jae-Keun LEE, Jeongwon YOON, Junho CHUNG, Junyeong JIN
  • Patent number: 11309477
    Abstract: A thermoelectric module including at least a first and a second thermoelectric element comprising a thermoelectric semiconductor; an electrode connecting the first and second thermoelectric elements; and at least a first and a second joining layer, the first joining layer positioned between the first thermoelectric element and the electrode, and the second joining layer positioned between the second thermoelectric element and the electrode; and at least a first and a second barrier layer including an alloy including Cu, Mo and Ti, the first barrier layer positioned between the first thermoelectric element and the first joining layer, and the second barrier layer positioned between the second thermoelectric element and the second joining layer.
    Type: Grant
    Filed: December 26, 2017
    Date of Patent: April 19, 2022
    Assignee: LG CHEM, LTD.
    Inventors: Su Jin Kim, Il Ha Lee, Pum Suk Park, Hyungju Oh, Dong Sik Kim, Byung Kyu Lim, Ki Hwan Kim, Cheol Hee Park
  • Publication number: 20220073601
    Abstract: The present disclosure relates to the pharmaceutical use of antagonists (e.g., an antibody or antigen-binding portion thereof) that specifically bind to FAM19A5 to treat or to diagnose a fibrosis and/or a fibrosis-associated disease in a subject in need thereof.
    Type: Application
    Filed: September 14, 2021
    Publication date: March 10, 2022
    Applicant: Neuracle Science Co., Ltd.
    Inventors: Bongcheol KIM, Jae-Keun LEE, Dong Sik KIM
  • Publication number: 20220064277
    Abstract: The present disclosure relates to the pharmaceutical use of antagonists (e.g., an antibody or antigen-binding portion thereof) that specifically bind to FAM19A5 to treat an atherosclerosis in a subject in need thereof.
    Type: Application
    Filed: December 26, 2019
    Publication date: March 3, 2022
    Applicant: NEURACLE SCIENCE CO., LTD.
    Inventors: Bongcheol KIM, Dong Sik KIM, Jae-Keun LEE, Juwon SHIM
  • Publication number: 20210388382
    Abstract: The present disclosure provides adeno-associated vims (AAV) vectors and uses thereof. In certain embodiments, the AAV vectors comprise a nucleic acid that encodes an antagonist against a family with sequence similarity 19, member A5 (FAM19A5) protein, e.g., anti-FAM19A5 antibody, e.g., anti-FAM19A5 scFv.
    Type: Application
    Filed: May 8, 2019
    Publication date: December 16, 2021
    Applicants: Neuracle Science Co., Ltd., Neuracle Genetics
    Inventors: Jong-Mook KIM, Dong Sik KIM, Juwon SHIM, Soon-gu KWON
  • Publication number: 20210347872
    Abstract: The present disclosure relates to the pharmaceutical use of antagonists (e.g., an antibody or antigen-binding portion thereof) that specifically bind to FAM19A5 to treat a retinopathy (e.g., diabetic retinopathy) and/or maculopathy (e.g., age-related macular degeneration) in a subject in need thereof.
    Type: Application
    Filed: October 15, 2019
    Publication date: November 11, 2021
    Applicant: NEURACLE SCIENCE CO., LTD.
    Inventors: Bongcheol KIM, Dong Sik KIM, Soon-gu KWON
  • Patent number: 11155613
    Abstract: The present disclosure relates to the pharmaceutical use of antagonists (e.g., an antibody or antigen-binding portion thereof) that specifically bind to FAM19A5 to treat or to diagnose a fibrosis and/or a fibrosis-associated disease in a subject in need thereof.
    Type: Grant
    Filed: June 27, 2018
    Date of Patent: October 26, 2021
    Assignee: Neuracle Science Co., Ltd.
    Inventors: Bongcheol Kim, Jae-Keun Lee, Dong Sik Kim
  • Publication number: 20210273149
    Abstract: A thermoelectric module that has excellent thermal, electric properties, can realize high joining force between thermoelectric elements and an electrode, and can maintain stable joining even at a high temperature.
    Type: Application
    Filed: May 3, 2021
    Publication date: September 2, 2021
    Applicant: LG CHEM, LTD.
    Inventors: Su Jin KIM, Il Ha LEE, Dong Sik KIM, Byung Kyu LIM, Cheol Hee PARK, Ki Hwan KIM
  • Patent number: 11056251
    Abstract: Disclosed herein is a patterning formation method including printing on a film base, a manufacturing method of an electrical device using the same, and a vehicular electrical device. More particularly, disclosed herein is a patterning formation method including arranging a poly cyclohexylene dimethylene terephthalate (PCT) film as a base film or as an upper part film such as a coverlay film, and patterning a material such as a metal by a printing method or connecting printing electronic technologies on at least a part of the PCT film. Also disclosed herein is a manufacturing method of an electrical device using the same and a vehicular electrical device.
    Type: Grant
    Filed: October 28, 2019
    Date of Patent: July 6, 2021
    Assignee: JIN YOUNG GLOBAL CO., LTD.
    Inventors: Dong Sik Kim, Kyong Do Kim
  • Patent number: 10998482
    Abstract: The present invention relates to a metal paste including: a first metal powder including nickel (Ni); a second metal powder including at least one selected from the group consisting of tin (Sn), zinc (Zn), bismuth (Bi), and indium (In); and a dispersing agent, and to a thermoelectric module which adopts a bonding technique using the metal paste.
    Type: Grant
    Filed: March 6, 2020
    Date of Patent: May 4, 2021
    Assignee: LG CHEM, LTD.
    Inventors: Dae Ki Lee, Dong-Sik Kim, Cheol-Hee Park
  • Publication number: 20210090756
    Abstract: The present invention provides an FFC using a PCT film as an insulating coating layer. The FFC comprises a lower insulating coating layer made of the PCT film; a lower adhesive layer made of polyester formed through a lower primer layer made of polyurethane material on the upper surface of the lower insulating coating layer; an upper insulating coating layer made of the PCT film; an upper adhesive layer made of polyester formed through an upper primer layer made of polyurethane material on a lower surface of the upper insulating coating layer; and a conductor wire layer interposed between the lower adhesive layer and the upper adhesive layer.
    Type: Application
    Filed: September 24, 2020
    Publication date: March 25, 2021
    Inventors: Kyong Do KIM, Dong Sik KIM
  • Publication number: 20210092838
    Abstract: A first embodiment of the present invention provides a flexible printed circuit board (FPCB) comprising a hot melt adhesive layer and a metal foil layer sequentially stacked on an insulating layer made of a PCT film; a flexible copper clad laminate (FCCL) having a circuit pattern on the metal foil layer; a coverlay adhered to the hot melt adhesive layer formed on the insulating layer made of the PCT film while covering the metal foil layer and also provides a method of manufacturing the FPCB. A second embodiment of the present invention provides an FPCB having a pressure-sensitive adhesive layer instead of the hot-melt adhesive layer, and a method for manufacturing the FPCB having the same, and the third embodiment of the present invention provides an FPCB having a UV cured layer instead of a hot melt adhesive layer, and a method for manufacturing the FPCB having the same.
    Type: Application
    Filed: September 24, 2020
    Publication date: March 25, 2021
    Inventors: Kyong Do KIM, Dong Sik KIM
  • Publication number: 20210070849
    Abstract: The present disclosure provides a method for the treatment of a neuropathic pain including a central neuropathic pain or a peripheral neuropathic pain in a subject comprising the administration of antibodies that specifically bind to human FAM19A5 and compositions comprising such antibodies. The present disclosure also provides methods for treating a neuropathic pain including a symptom of neuropathic pain, and/or an underlining cause of a neuropathic pain, by administering an antibody that specifically binds to human FAM19A5. In a specific aspect, the method comprises administering antibodies specifically bind to human FAM19A5, e.g., binds to soluble human FAM19A5 with a KD of 10 nM or less, or binds to membrane bound human FAM19A5 with a KD of 10 nM or less, or both, as measured by a method known in the art, e.g., ELISA.
    Type: Application
    Filed: April 24, 2019
    Publication date: March 11, 2021
    Applicant: Neuracle Science Co., Ltd.
    Inventors: Bongcheol KIM, Dong Sik KIM, Soon-gu KWON
  • Publication number: 20210001287
    Abstract: Provided is a gas-dissolved water generating apparatus in which a pressure pump and a multi-stage mixer are sequentially arranged on at least one conduit; a circulation pipe connecting an inlet side of the pressure pump and a outlet side of the pressure pump is positioned on the conduit; a gas supply unit for supplying a predetermined external gas to one side of the circulation pipe, which is connected to the inlet side of the pressure pump, via a gas supply pipe; the gas supply unit and the circulation pipe are connected through a three-way valve, and the three-way valve is configured to have a structure of a venturi pipe having wide inlet and outlet channels and a narrow interior channel along the circulation pipe, so that a gas supplied from the gas supply unit is independently sucked.
    Type: Application
    Filed: May 14, 2018
    Publication date: January 7, 2021
    Inventor: Dong Sik KIM
  • Patent number: 10851175
    Abstract: The present invention relates to an antibody specifically bound to mesothelin (MSLN), a nucleic acid encoding the antibody, a vector and a host cell including the nucleic acid, a method for producing the antibody, and a pharmaceutical composition for treating cancer or tumor including the antibody as an active ingredient. The antibody specifically bound to the mesothelin according to the present invention has high affinity and specificity to an antigen, such that it is possible to develop an antibody effectively usable for treatment or diagnosis of cancer or tumor diseases.
    Type: Grant
    Filed: September 23, 2016
    Date of Patent: December 1, 2020
    Assignees: MOGAM INSTITUTE FOR BIOMEDICAL RESEARCH, GREEN CROSS CORPORATION
    Inventors: Dong-Sik Kim, Eun Jung Song, Mijung Lee, Eun-Hee Lee, Miyoung Oh, Jae Chan Park, Kisu Kim, Sujeong Kim, Hyung-Kwon Lim, Kyuhyun Lee, Jongwha Won, Soongyu Choi, Young Seoub Park