Abstract: The present invention provides an imaging probe for imaging mammalian tissues and structures using high resolution imaging, including high frequency ultrasound and optical coherence tomography. The imaging probes structures using high resolution imaging use combined high frequency ultrasound (IVUS) and optical imaging methods such as optical coherence tomography (OCT) and to accurate co-registering of images obtained from ultrasound image signals and optical image signals during scanning a region of interest.

Abstract: A wearable device for detecting eating episodes uses a contact microphone to provide audio signals through an analog front end to an analog-to-digital converter to digitize the audio and provide digitized audio to a processor; and a processor configured with firmware in a memory to extract features from the digitized audio. A classifier determines eating episodes from the extracted features. In embodiments, messages describing the detected eating episodes are transmitted to a cell phone, insulin pump, or camera configured to record video of the wearer's mouth.

Abstract: A method of operating a VR or AR head mounted display (HMD) system includes obtaining a video performance parameter for a video signal, selecting a clock frequency for video data transfer within the HMD system based on the video performance parameter, detecting one or more available frequency bands for a wireless data connection between a host device and the HMD system, and selecting a frequency band from the one or more available frequency bands for the wireless data connection, based on a predetermined connection suitability parameter for the one or more available frequency bands and based on the selected clock frequency for video data transfer within the HMD system. The method further includes establishing a wireless connection between the host device and the HMD system over the selected frequency band.

Abstract: Disclosed are a method and a user behavior data processing device, as well as a computer-readable storage medium. The user behavior data processing method includes: obtaining log information stored in a preset server at a fixed time, wherein, the log information comprises user behavior data which is captured and sent to the preset server by client; determining that whether row data satisfying a preset format exists in each row data of the log information, wherein, the row data is the data corresponding to each row of the log information; setting the row data satisfying the preset format as user behavior information; performing data statistics on the user behavior information according to a preset rule to obtain statistical information of the user behavior information.

Abstract: In at least one embodiment, a reinforcement-learning-based searching approach is used to produce a training configuration for a machine-learning model. In at least one embodiment, 3D medical image segmentation is performed using learned image preprocessing parameters.

Abstract: Disclosed herein is an apparatus and method for fine tuning properties of a thin film. The method of forming a piezoelectric film includes (a) depositing a first piezoelectric film layer on a surface of a substrate by a first physical vapor deposition (PVD) process. The method includes (b) depositing a second piezoelectric film layer, on top of and in contact with the first piezoelectric film layer, by a second PVD process. A temperature of the substrate is (c) reduced after forming the first piezoelectric film layer and before forming the second piezoelectric film layer. The temperature is reduced by performing a process for a first period of time. Processes (a), (b) and (c) are additionally performed one or more times. Process (c) is performed for a second period of time. The second period of time is different than the first period of time.

Abstract: The present disclosure provides a dimer formed by two polypeptide chains, with each of the two polypeptide chains comprising an antibody Fc subunit, wherein the dimer comprises two or more immunoglobulin single variable domains (ISVDs), at least one of the ISVDs is specific for PD-L1, and at least one of the ISVDs is specific for CTLA4.

Abstract: The present disclosure provides a side chain liquid crystal epoxy monomer (S-LCEM) and a preparation method thereof, and a side chain liquid crystal epoxy resin (S-LCER) with high intrinsic thermal conductivity, and belongs to the technical field of epoxy resin materials. There are biphenyl mesogenic groups with strong rigidity in a molecular structure of the S-LCEM provided in the present disclosure and there are also flexible connections among chain segments, which promotes the ordered arrangement of S-LCEM molecular chains during a curing process. The highly-ordered arrangement of such mesogenic units is conducive to the formation of a local crystalloid structure, so that a heat flow is transferred along a direction of the ordered molecular chain, which effectively inhibits the scattering of phonons in the S-LCER with high intrinsic thermal conductivity and greatly improves the intrinsic thermal conductivity of the S-LCER with high intrinsic thermal conductivity.

Abstract: A method for encapsulating openings in a display area includes: forming an intermediate layer having an isolation hole and an assembly via on a substrate, the isolation hole dividing the intermediate layer into separate display portion and isolation portion and the assembly via being spaced apart from the isolation hole by the isolation portion; forming a groove on a side of the isolation portion facing the display portion and/or on a side of the isolation portion away from the display portion; forming a light emitting layer including a first light emitting portion, a second light emitting portion, a third light emitting portion, and a fourth light emitting portion, wherein the third light emitting portion is separate from at least one of the second light emitting portion and the fourth light emitting portion; and forming an encapsulation layer that covers the light emitting layer and the isolation portion, and is filled in a groove.

Abstract: Systems and methods for surgical guidance and image registration are provided, in which three-dimensional image data associated with an object or patient is registered to topological image data obtained using a surface topology imaging device. The surface topology imaging device may be rigidly attached to an optical position measurement system that also tracks fiducial markers on a movable instrument. The instrument may be registered to the topological image data, such that the topological image data and the movable instrument are registered to the three-dimensional image data. The three-dimensional image data may be CT or MRI data associated with a patient. The system may also co-register images pertaining to a surgical plan with the three-dimensional image data. In another aspect, the surface topology imaging device may be configured to directly track fiducial markers on a movable instrument. The fiducial markers may be tracked according to surface texture.

Abstract: The present invention relates to a method of activating an organic coating to enhance adhesion of the coating to a further coating and/or to other entities comprising applying a solvent and a surface chemistry and/or surface topography modifying agent to the organic coating. The invention also relates to a coated substrate having an activated coating, wherein the adhesion of the coating to a further coating and/or other entities has been enhanced by application of a solvent and a surface chemistry and/or surface topography modifying agent to the coating. The invention further relates to an activation treatment for an organic coating to enhance adhesion of the coating to a further coating and/or to other entities comprising a solvent and a surface chemistry and/or surface topography modifying agent and a method for the preparation of the activation treatment.

Abstract: Methods and apparatus for automated medical image analysis using deep learning networks are disclosed. In a method of automatically performing a medical image analysis task on a medical image of a patient, a medical image of a patient is received. The medical image is input to a trained deep neural network. An output model that provides a result of a target medical image analysis task on the input medical image is automatically estimated using the trained deep neural network. The trained deep neural network is trained in one of a discriminative adversarial network or a deep image-to-image dual inverse network.

Abstract: A valve bridge system comprises a valve bridge configured to extend between at least two engine valves of an internal combustion engine. In one embodiment, a valve bridge guide is operatively connected to the valve bridge and configured to extend between at least two valve springs respectively corresponding to the at least two engine valves, the valve bridge guide defining a surface conforming to a valve spring of the at least two valve springs. In another embodiment, the valve bridge guide may comprise at least a first member maintained in a first fixed position relative to and at a predetermined distance from the valve bridge. In both embodiments, the valve bridge guide is configured to avoid contact with the valve bridge in a controlled state, but to permit contact with valve bridge to resist uncontrolled movement of the valve bridge.

Abstract: The present disclosure provides an iron-based amorphous alloy as shown in formula (I): FeaSibBcPdMe (I); wherein a, b, c, d, and e are each independently atomic percentages of corresponding components; 80.5?a?84.0, 3.0?b?9.0, 8.0?c?15.0, 0.001?d?0.3, e?0.4, and a+b+c+d+e=100; M is impurity element. The present disclosure provides an iron-based amorphous strip which has a saturation magnetic induction less than 1.62T. The present disclosure also provides a method for preparing the iron-based amorphous alloy. Further, after appropriate heat treatment, excellent soft magnetic properties will be obtained. The alloy material can be used as core material in the manufacture of power transformer, generator and engine.

Abstract: The present disclosure is appropriate for the technical field of packaging bag materials, and provides a full biodegradable high-barrier multi-layer composite material and a preparation method thereof as well as a packaging bag. The full biodegradable high-barrier multi-layer composite material comprises the following components: polylactic acid, terephthalic acid-adipic acid-butanediol copolyester, polyvinyl alcohol, polyurethane glue and starch carrageenan. Embodiments of the present disclosure provide the full biodegradable high-barrier multi-layer composite material which is obtained by using the terephthalic acid-adipic acid-butanediol copolyester as a degradable layer, using polyvinyl alcohol as a barrier layer and by composing the degradable layer with the barrier layer via polyurethane glue and starch carrageenan. Through the present disclosure, the problems, such as high oxygen permeation rate, poor barrier property and poor preservation degree, in the existing degraded film can be solved.

Abstract: A portable compute case for eyewear devices may include a wireless transceiver and a computation component that includes at least one processor. The portable compute case may be configured to house an eyewear device; establish, using the wireless transceiver, a communicative connection between the portable compute case and the eyewear device; generate, using the computation component, processed sensor data; and transmit, using the wireless transceiver, the processed sensor data to the eyewear device for display by the eyewear device. Various other systems and methods are also disclosed.

Abstract: A calibration system includes a grid assembly, a platform, and a controller. The grid assembly includes at least one planar grid. The platform couples to a device under test (DUT) and move the DUT to a plurality of test positions in accordance with a motion sequence. Each test position is reached by a rotation about at most two different axes, and as the DUT moves through the motion sequence, at least one camera on the DUT captures image information describing portions of the grid assembly and an inertial measurement unit (IMU) on the DUT captures IMU information. The controller determines calibration information for the at least one camera on the DUT and for the IMU based in part on a parameterized model of the motion sequence of the DUT, the captured image information, and the captured IMU information.

Abstract: A disclosed circuit prototyping system includes a hardware interface module configured for electronically connecting to a physical electronic device, a virtual circuit design interface to construct a virtual circuit for a plurality of virtual circuit devices including a virtual counterpart of the physical electronic device, and a circuit simulator configured to simulate the virtual circuit including communicating data with the physical electronic device by way of communication with the hardware interface module.

Abstract: Systems and methods for surgical guidance and image registration are provided, in which three-dimensional image data associated with an object or patient is registered to topological image data obtained using a surface topology imaging device. The surface topology imaging device may be rigidly attached to an optical position measurement system that also tracks fiducial markers on a movable instrument. The instrument may be registered to the topological image data, such that the topological image data and the movable instrument are registered to the three-dimensional image data. The three-dimensional image data may be CT or MRI data associated with a patient. The system may also co-register images pertaining to a surgical plan with the three-dimensional image data. In another aspect, the surface topology imaging device may be configured to directly track fiducial markers on a movable instrument. The fiducial markers may be tracked according to surface texture.

Abstract: The present disclosure provides a dimer formed by two polypeptide chains, with each of the two polypeptide chains comprising an antibody Fc subunit, wherein the dimer comprises two or more immunoglobulin single variable domains (ISVDs), at least one of the ISVDs is specific for PD-L1, and at least one of the ISVDs is specific for CTLA4.