Patents by Inventor Dongdong Chen

Dongdong Chen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240221128
    Abstract: The disclosure herein describes training an encoder network to inpaint images with masked portions. A primary encoding process is used to encode a visible portion of a masked input image into encoded token data. The encoded token data is then decoded into both pixel regression output and feature prediction output, wherein both outputs include inpainted image data associated with the masked portion of the masked input image. A pixel regression loss is determined using the pixel regression output and pixel data of an unmasked version of the masked input image. A feature prediction loss is determined using the feature prediction output and ground truth encoding output of the unmasked version of the masked input image. The primary encoding process is then trained using the pixel regression loss and the feature prediction loss, whereby the primary encoding process is trained to encode structural features of input images into encoded token data.
    Type: Application
    Filed: May 19, 2022
    Publication date: July 4, 2024
    Inventors: Dongdong CHEN, Jianmin BAO, Ting ZHANG, Lu YUAN, Dong CHEN, Fang WEN, Xiaoyi DONG
  • Publication number: 20240207078
    Abstract: A Z-shaped braided stent capable of being implanted into a human organ. The Z-shaped braided stent comprises: a first tubular wire mesh having N braided rings and formed by continuously braiding first braid wires (I) in a Z shape, each braided ring of the first tubular wire mesh having a plurality of first bending points (A) formed by bending the first braid wires (I) and distributed at intervals; and a second tubular wire mesh having N braided rings and formed by continuously braiding second braid wires (II) in a Z shape, each braided ring of the second tubular wire mesh having a plurality of second bending points (B) formed by bending the second braid wires (II) and distributed at intervals. By hooking the first bending points (A) with the second bending points (B), the second tubular wire mesh and the first tubular wire mesh are connected together to form the Z-shaped braided stent. The braided stent can be subjected to axially deformable compression, but axially basically non-deformable stretching.
    Type: Application
    Filed: April 12, 2022
    Publication date: June 27, 2024
    Inventors: Xuemin Zhang, Tao Wang, Xunming Ji, Jianliang Zheng, Jun Lu, Yan Yu, Ming Li, Qiaoyu Zhang, Dongdong Chen, Yu Zhao, Xuzhi Zhang, Xianguo Meng, Xiaolin Yang
  • Patent number: 12012390
    Abstract: The present invention provides flavone derivatives having the general formula (I) which are useful for the treatment of Hepatitis B Virus infection (HBV). The compounds act as cccDNA (covalently closed circular DMA) inhibitors.
    Type: Grant
    Filed: September 11, 2019
    Date of Patent: June 18, 2024
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Song Feng, Chungen Liang, Yongfu Liu, Hong Shen, Xuefei Tan, Jun Wu, Dongdong Chen, Chao Li, Li Wang
  • Publication number: 20240176619
    Abstract: The present disclosure describes a digital signal processing (DSP) block that includes a plurality of columns of weight registers and a plurality of inputs configured to receive a first plurality of values and a second plurality of values. The first plurality of values is stored in the plurality of columns of weight registers after being received. Additionally, the DSP block includes a plurality of multipliers configured to simultaneously multiply each value of the first plurality of values by each value of the second plurality of values.
    Type: Application
    Filed: February 7, 2024
    Publication date: May 30, 2024
    Inventors: Martin Langhammer, Dongdong Chen, Jason R. Bergendahl
  • Patent number: 11989956
    Abstract: Systems and methods for object detection generate a feature pyramid corresponding to image data, and rescaling the feature pyramid to a scale corresponding to a median level of the feature pyramid, wherein the rescaled feature pyramid is a four-dimensional (4D) tensor. The 4D tensor is reshaped into a three-dimensional (3D) tensor having individual perspectives including scale features, spatial features, and task features corresponding to different dimensions of the 3D tensor. The 3D tensor is used with a plurality of attention layers to update a plurality of feature maps associated with the image data. Object detection is performed on the image data using the updated plurality of feature maps.
    Type: Grant
    Filed: April 5, 2021
    Date of Patent: May 21, 2024
    Assignee: Microsoft Technology Licensing, LLC
    Inventors: Xiyang Dai, Yinpeng Chen, Bin Xiao, Dongdong Chen, Mengchen Liu, Lu Yuan, Lei Zhang
  • Patent number: 11970495
    Abstract: This invention relates to indolizine derivatives and their use in medicine. In particular, the present invention discloses novel substituted indolizine derivatives of formula I, or an isotopically labeled compound thereof, or an optical isomer thereof, a geometric isomer thereof, a tautomer thereof or a mixture of various isomers, or a pharmaceutically acceptable salt thereof, or a prodrug thereof. The invention also relates to the use of these compounds in medicine.
    Type: Grant
    Filed: April 10, 2023
    Date of Patent: April 30, 2024
    Assignee: KIND PHARMACEUTICAL
    Inventors: Dong Liu, Dongdong Chen, Biao Deng, Xiangyun Tu, Zinan Fang, Haohao Wu, Danyan Gu
  • Patent number: 11945817
    Abstract: This invention relates to indolizine derivatives and their use in medicine. In particular, the present invention discloses novel substituted indolizine derivatives of formula I, or an isotopically labeled compound thereof, or an optical isomer thereof, a geometric isomer thereof, a tautomer thereof or a mixture of various isomers, or a pharmaceutically acceptable salt thereof, or a prodrug thereof. The invention also relates to the use of these compounds in medicine.
    Type: Grant
    Filed: April 10, 2023
    Date of Patent: April 2, 2024
    Assignee: KIND PHARMACEUTICAL
    Inventors: Dong Liu, Dongdong Chen, Biao Deng, Xiangyun Tu, Zinan Fang, Haohao Wu, Danyan Gu
  • Patent number: 11907719
    Abstract: The present disclosure describes a digital signal processing (DSP) block that includes a plurality of columns of weight registers and a plurality of inputs configured to receive a first plurality of values and a second plurality of values. The first plurality of values is stored in the plurality of columns of weight registers after being received. Additionally, the DSP block includes a plurality of multipliers configured to simultaneously multiply each value of the first plurality of values by each value of the second plurality of values.
    Type: Grant
    Filed: June 26, 2020
    Date of Patent: February 20, 2024
    Assignee: Intel Corporation
    Inventors: Martin Langhammer, Dongdong Chen, Jason R. Bergendahl
  • Patent number: 11810385
    Abstract: A computer-vision method includes recognizing a feature representation of a query image depicting an unknown subject. A similarity score is computed between the representation of the query image and feature representations of a plurality of gallery images collectively depicting two or more different subjects with at least two or more gallery images for each subject, and each gallery image having a label identifying which of the subjects is depicted. One or more updated feature representations of the query image are sequentially iterated based on one or more of the computed similarity scores. For each of the one or more updated feature representations, an updated similarity score is computed between the updated feature representation and the feature representations of each of the gallery images. The unknown subject is identified based on a gallery image having a highest updated similarity score.
    Type: Grant
    Filed: December 28, 2020
    Date of Patent: November 7, 2023
    Assignee: Microsoft Technology Licensing, LLC
    Inventors: Dongdong Chen, Dengpan Fu, Jingdong Wang, Jianmin Bao
  • Publication number: 20230351558
    Abstract: The disclosure herein describes generating an inpainted image from a masked image using a patch-based encoder and an unquantized transformer. An image including a masked region and an unmasked region is received, and the received image is divided into a plurality of patches including masked patches. The plurality of patches is encoded into a plurality of feature vectors, wherein each patch is encoded to a feature vector. Using a transformer, a predicted token is generated for each masked patch using a feature vector encoded from the masked patch, and a quantized vector of the masked patch is determined using generated predicted token and a masked patch-specific codebook. The determined quantized vector of the masked patch is included into a set of quantized vectors associated with the plurality of patches, and an output image is generated from the set of quantized vectors using a decoder.
    Type: Application
    Filed: April 29, 2022
    Publication date: November 2, 2023
    Inventors: Dongdong CHEN, Xiyang DAI, Yinpeng CHEN, Mengchen LIU, Lu YUAN
  • Publication number: 20230342111
    Abstract: An integrated circuit with specialized processing blocks is provided. A specialized processing block may be optimized for machine learning algorithms and may include a multiplier data path that feeds an adder data path. The multiplier data path may be decomposed into multiple partial product generators, multiple compressors, and multiple carry-propagate adders of a first precision. Results from the carry-propagate adders may be added using a floating-point adder of the first precision. Results from the floating-point adder may be optionally cast to a second precision that is higher or more accurate than the first precision. The adder data path may include an adder of the second precision that combines the results from the floating-point adder with zero, with a general-purpose input, or with other dot product terms. Operated in this way, the specialized processing block provides a technical improvement of greatly increasing the functional density for implementing machine learning algorithms.
    Type: Application
    Filed: June 30, 2023
    Publication date: October 26, 2023
    Inventors: Martin Langhammer, Dongdong Chen, Kevin Hurd
  • Publication number: 20230295109
    Abstract: The present invention relates to compounds of formula (I), (I), wherein R1, R2, R3, R4 and A are as described herein, and their pharmaceutically acceptable salt thereof, and compositions including the compounds and methods of using the compounds.
    Type: Application
    Filed: August 2, 2021
    Publication date: September 21, 2023
    Applicant: Hoffmann-La Roche Inc.
    Inventors: Dongdong CHEN, Fabian DEY, Xin HONG, Xuefei TAN, Jiasu XU, Wei ZHU, Ge ZOU
  • Publication number: 20230279001
    Abstract: The present invention relates to compounds of formula (I), wherein R1, R2, R3, R4, R5 and A are as described herein, and their pharmaceutically acceptable salt thereof, and compositions including the compounds and methods of using the compounds.
    Type: Application
    Filed: August 2, 2021
    Publication date: September 7, 2023
    Applicant: Hoffmann-La Roche Inc.
    Inventors: Dongdong CHEN, Jianguo CHEN, Fabian DEY, Xin HONG, Xuefei TAN, Jiasu XU, Weixing ZHANG, Wei ZHU, Ge ZOU
  • Publication number: 20230257379
    Abstract: This invention relates to indolizine derivatives and their use in medicine. In particular, the present invention discloses novel substituted indolizine derivatives of formula I, or an isotopically labeled compound thereof, or an optical isomer thereof, a geometric isomer thereof, a tautomer thereof or a mixture of various isomers, or a pharmaceutically acceptable salt thereof, or a prodrug thereof. The invention also relates to the use of these compounds in medicine.
    Type: Application
    Filed: April 10, 2023
    Publication date: August 17, 2023
    Inventors: Dong LIU, Dongdong CHEN, Biao DENG, Xiangyun TU, Zinan FANG, Haohao WU, Danyan GU
  • Patent number: 11726744
    Abstract: An integrated circuit with specialized processing blocks is provided. A specialized processing block may be optimized for machine learning algorithms and may include a multiplier data path that feeds an adder data path. The multiplier data path may be decomposed into multiple partial product generators, multiple compressors, and multiple carry-propagate adders of a first precision. Results from the carry-propagate adders may be added using a floating-point adder of the first precision. Results from the floating-point adder may be optionally cast to a second precision that is higher or more accurate than the first precision. The adder data path may include an adder of the second precision that combines the results from the floating-point adder with zero, with a general-purpose input, or with other dot product terms. Operated in this way, the specialized processing block provides a technical improvement of greatly increasing the functional density for implementing machine learning algorithms.
    Type: Grant
    Filed: March 26, 2021
    Date of Patent: August 15, 2023
    Assignee: Intel Corporation
    Inventors: Martin Langhammer, Dongdong Chen, Kevin Hurd
  • Publication number: 20230242527
    Abstract: This invention relates to indolizine derivatives and their use in medicine. In particular, the present invention discloses novel substituted indolizine derivatives of formula I, or an isotopically labeled compound thereof, or an optical isomer thereof, a geometric isomer thereof, a tautomer thereof or a mixture of various isomers, or a pharmaceutically acceptable salt thereof, or a prodrug thereof. The invention also relates to the use of these compounds in medicine.
    Type: Application
    Filed: April 10, 2023
    Publication date: August 3, 2023
    Inventors: Dong LIU, Dongdong CHEN, Biao DENG, Xiangyun TU, Zinan FANG, Haohao WU, Danyan GU
  • Patent number: 11708344
    Abstract: The present invention provides novel compounds having the general formula (Formula I): wherein R1 to R6, G1, G2, A1 to A4 and m are as described herein, compositions including the compounds and methods of using the compounds.
    Type: Grant
    Filed: October 1, 2019
    Date of Patent: July 25, 2023
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Dongdong Chen, Song Feng, Min Jiang, Yongfu Liu, Jiamin Zheng
  • Publication number: 20230219959
    Abstract: The present invention relates to compounds of formula (I), wherein R1 to R3 and n are as described herein, and their pharmaceutically acceptable salt thereof, and compositions including the compounds and methods of using the compounds.
    Type: Application
    Filed: November 17, 2020
    Publication date: July 13, 2023
    Applicant: Hoffmann-La Roche Inc.
    Inventors: Dongdong CHEN, Fabian DEY, Dong DING, Hongtao XU, Wei ZHU, Ge ZOU
  • Patent number: 11655249
    Abstract: This invention relates to indolizine derivatives and their use in medicine. In particular, the present invention discloses novel substituted indolizine derivatives of formula I, or an isotopically labeled compound thereof, or an optical isomer thereof, a geometric isomer thereof, a tautomer thereof or a mixture of various isomers, or a pharmaceutically acceptable salt thereof, or a prodrug thereof. The invention also relates to the use of these compounds in medicine.
    Type: Grant
    Filed: April 23, 2021
    Date of Patent: May 23, 2023
    Assignee: KIND PHARMACEUTICAL
    Inventors: Dong Liu, Dongdong Chen, Biao Deng, Xiangyun Tu, Zinan Fang, Haohao Wu, Danyan Gu
  • Publication number: 20230144399
    Abstract: The present invention provides novel compounds having the general formula: wherein R1 to R11 are as described herein, compositions including the compounds and methods of using the compounds.
    Type: Application
    Filed: December 14, 2018
    Publication date: May 11, 2023
    Applicant: Hoffmann-La Roche Inc.
    Inventors: Song FENG, Zongxing QIU, Guolong WU, Dongdong CHEN, Chao LI