Patents by Inventor Dongdong Chen

Dongdong Chen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20220363657
    Abstract: The present invention provides flavone derivatives having the general formula (I) which are useful for the treatment of Hepatitis B Virus infection (HBV). The compounds act as cccDNA (covalently closed circular DMA) inhibitors.
    Type: Application
    Filed: September 11, 2019
    Publication date: November 17, 2022
    Applicant: Hoffmann-La Roche Inc.
    Inventors: Song FENG, Chungen LIANG, Yongfu LIU, Hong SHEN, Xuefei TAN, Jun WU, Dongdong CHEN, Chao LI, Li WANG
  • Patent number: 11494186
    Abstract: The present disclosure describes a digital signal processing (DSP) block that includes a plurality of columns of weight registers and a plurality of inputs configured to receive a first plurality of values and a second plurality of values. The first plurality of values is stored in the plurality of columns of weight registers after being received. Additionally, the DSP block includes a plurality of multipliers configured to simultaneously multiply each value of the first plurality of values by each value of the second plurality of values.
    Type: Grant
    Filed: June 26, 2020
    Date of Patent: November 8, 2022
    Assignee: Intel Corporation
    Inventors: Martin Langhammer, Dongdong Chen, Jason R. Bergendahl
  • Publication number: 20220348549
    Abstract: The present invention provides novel compounds having the general formula: wherein R1 to R6 and A are as described herein, compositions including the compounds and methods of using the compounds.
    Type: Application
    Filed: August 26, 2020
    Publication date: November 3, 2022
    Applicant: Hoffmann-La Roche Inc.
    Inventors: Dongdong CHEN, Song FENG, Chungen LIANG, Chao LI, Zongxing QIU, Xuefei TAN, Guolong WU
  • Publication number: 20220318541
    Abstract: Systems and methods for object detection generate a feature pyramid corresponding to image data, and rescaling the feature pyramid to a scale corresponding to a median level of the feature pyramid, wherein the rescaled feature pyramid is a four-dimensional (4D) tensor. The 4D tensor is reshaped into a three-dimensional (3D) tensor having individual perspectives including scale features, spatial features, and task features corresponding to different dimensions of the 3D tensor. The 3D tensor is used with a plurality of attention layers to update a plurality of feature maps associated with the image data. Object detection is performed on the image data using the updated plurality of feature maps.
    Type: Application
    Filed: April 5, 2021
    Publication date: October 6, 2022
    Inventors: Xiyang DAI, Yinpeng CHEN, Bin XIAO, Dongdong CHEN, Mengchen LIU, Lu YUAN, Lei ZHANG
  • Publication number: 20220213049
    Abstract: The present invention provides novel compounds having the general formula: (I) wherein R1 to R10, Gi, G2 and m are as described herein, compositions including the impounds and methods of using the compounds for the treatment of hepatitis B.
    Type: Application
    Filed: January 16, 2020
    Publication date: July 7, 2022
    Applicant: Hoffmann-La Roche Inc.
    Inventors: Dongdong CHEN, Song FENG, Chungen LIANG, Kun MIAO, Xuefei TAN, Hong SHEN
  • Publication number: 20220207264
    Abstract: A computer-vision method includes recognizing a feature representation of a query image depicting an unknown subject. A similarity score is computed between the representation of the query image and feature representations of a plurality of gallery images collectively depicting two or more different subjects with at least two or more gallery images for each subject, and each gallery image having a label identifying which of the subjects is depicted. One or more updated feature representations of the query image are sequentially iterated based on one or more of the computed similarity scores. For each of the one or more updated feature representations, an updated similarity score is computed between the updated feature representation and the feature representations of each of the gallery images. The unknown subject is identified based on a gallery image having a highest updated similarity score.
    Type: Application
    Filed: December 28, 2020
    Publication date: June 30, 2022
    Applicant: Microsoft Technology Licensing, LLC
    Inventors: Dongdong CHEN, Dengpan FU, Jingdong WANG, Jianmin BAO
  • Publication number: 20220188595
    Abstract: A computer device for automatic feature detection comprises a processor, a communication device, and a memory configured to hold instructions executable by the processor to instantiate a dynamic convolution neural network, receive input data via the communication network, and execute the dynamic convolution neural network to automatically detect features in the input data. The dynamic convolution neural network compresses the input data from an input space having a dimensionality equal to a predetermined number of channels into an intermediate space having a dimensionality less than the number of channels. The dynamic convolution neural network dynamically fuses the channels into an intermediate representation within the intermediate space and expands the intermediate representation from the intermediate space to an expanded representation in an output space having a higher dimensionality than the dimensionality of the intermediate space.
    Type: Application
    Filed: December 16, 2020
    Publication date: June 16, 2022
    Applicant: Microsoft Technology Licensing, LLC
    Inventors: Yinpeng CHEN, Xiyang DAI, Mengchen LIU, Dongdong CHEN, Lu YUAN, Zicheng LIU, Ye YU, Mei CHEN, Yunsheng LI
  • Publication number: 20220188599
    Abstract: A neural architecture search (NAS) with a weak predictor comprises: receiving network architecture scoring information; iteratively sampling a search space, wherein the sampling comprises: generating a set of candidate architectures within the search space; learning a first predictor; evaluating performance of the candidate architectures; and based on at least the performance of the set of candidate architectures and the network architecture scoring information, refining the search space to a smaller search space; based on at least the network architecture scoring information, thresholding the performance of candidate architectures to determine scored output candidate architectures; and reporting the scored output candidate architectures. In some examples, the candidate architectures each comprise a machine learning (ML) model, for example a neural network (NN).
    Type: Application
    Filed: December 15, 2020
    Publication date: June 16, 2022
    Inventors: Xiyang DAI, Dongdong CHEN, Yinpeng CHEN, Mengchen LIU, Ye YU, Zicheng LIU, Mei CHEN, Lu YUAN, Junru WU
  • Publication number: 20220169639
    Abstract: The present invention provides the compounds having the general formula: (I) wherein R1 to R8, and X are as described herein, compositions including the compounds and methods of using the compounds.
    Type: Application
    Filed: December 11, 2019
    Publication date: June 2, 2022
    Applicant: Hoffmann-La Roche Inc.
    Inventors: Song FENG, Jiamin ZHENG, Yongfu LIU, Dongdong CHEN, Hong SHEN, Xuefei TAN
  • Patent number: 11308576
    Abstract: In accordance with implementations of the subject matter described herein, there is proposed a solution of visual stylization of stereoscopic images. In the solution, a first feature map for a first source image and a second feature map for a second source image are extracted. The first and second source images correspond to first and second views of a stereoscopic image, respectively. A first unidirectional disparity from the first source image to the second source image is determined based on the first and second source images. First and second target images having a specified visual style are generated by processing the first and second feature maps based on the first unidirectional disparity. Through the solution, a disparity between two source images of a stereoscopic image are taken into account when performing the visual style transfer, thereby maintaining a stereoscopic effect in the stereoscopic image consisting of the target images.
    Type: Grant
    Filed: January 8, 2019
    Date of Patent: April 19, 2022
    Assignee: Microsoft Technology Licensing, LLC
    Inventors: Lu Yuan, Gang Hua, Jing Liao, Dongdong Chen
  • Publication number: 20220012015
    Abstract: An integrated circuit with specialized processing blocks are provided. A specialized processing block may be optimized for machine learning algorithms and may include a multiplier data path that feeds an adder data path. The multiplier data path may be decomposed into multiple partial product generators, multiple compressors, and multiple carry-propagate adders of a first precision. Results from the carry-propagate adders may be added using a floating-point adder of the first precision. Results from the floating-point adder may be optionally cast to a second precision that is higher or more accurate than the first precision. The adder data path may include an adder of the second precision that combines the results from the floating-point adder with zero, with a general-purpose input, or with other dot product terms. Operated in this way, the specialized processing block provides a technical improvement of greatly increasing the functional density for implementing machine learning algorithms.
    Type: Application
    Filed: September 24, 2021
    Publication date: January 13, 2022
    Inventors: Martin Langhammer, Dongdong Chen, Kevin Hurd
  • Patent number: 11180525
    Abstract: The present invention relates to compounds of formula (I), wherein R1, R2 and R3 are as described herein, and their prodrugs or pharmaceutically acceptable salt, enantiomer or diastereomer thereof, and compositions including the compounds and methods of using the compounds.
    Type: Grant
    Filed: April 13, 2020
    Date of Patent: November 23, 2021
    Assignee: Hoffmann-La Roche, Inc.
    Inventors: Dongdong Chen, Song Feng, Lu Gao, Chao Li, Baoxia Wang, Lisha Wang, Hongying Yun, Xiufang Zheng
  • Patent number: 11175892
    Abstract: An integrated circuit with specialized processing blocks are provided. A specialized processing block may be optimized for machine learning algorithms and may include a multiplier data path that feeds an adder data path. The multiplier data path may be decomposed into multiple partial product generators, multiple compressors, and multiple carry-propagate adders of a first precision. Results from the carry-propagate adders may be added using a floating-point adder of the first precision. Results from the floating-point adder may be optionally cast to a second precision that is higher or more accurate than the first precision. The adder data path may include an adder of the second precision that combines the results from the floating-point adder with zero, with a general-purpose input, or with other dot product terms. Operated in this way, the specialized processing block provides a technical improvement of greatly increasing the functional density for implementing machine learning algorithms.
    Type: Grant
    Filed: November 20, 2017
    Date of Patent: November 16, 2021
    Assignee: Intel Corporation
    Inventors: Martin Langhammer, Dongdong Chen
  • Publication number: 20210253570
    Abstract: This invention relates to indolizine derivatives and their use in medicine. In particular, the present invention discloses novel substituted indolizine derivatives of formula I, or an isotopically labeled compound thereof, or an optical isomer thereof, a geometric isomer thereof, a tautomer thereof or a mixture of various isomers, or a pharmaceutically acceptable salt thereof, or a prodrug thereof. The invention also relates to the use of these compounds in medicine.
    Type: Application
    Filed: April 23, 2021
    Publication date: August 19, 2021
    Inventors: Dong LIU, Dongdong Chen, Biao Deng, Xiangyun Tu, Zinan Fang, Haohao Wu, Danyan Gu
  • Publication number: 20210240440
    Abstract: An integrated circuit with specialized processing blocks is provided. A specialized processing block may be optimized for machine learning algorithms and may include a multiplier data path that feeds an adder data path. The multiplier data path may be decomposed into multiple partial product generators, multiple compressors, and multiple carry-propagate adders of a first precision. Results from the carry-propagate adders may be added using a floating-point adder of the first precision. Results from the floating-point adder may be optionally cast to a second precision that is higher or more accurate than the first precision. The adder data path may include an adder of the second precision that combines the results from the floating-point adder with zero, with a general-purpose input, or with other dot product terms. Operated in this way, the specialized processing block provides a technical improvement of greatly increasing the functional density for implementing machine learning algorithms.
    Type: Application
    Filed: March 26, 2021
    Publication date: August 5, 2021
    Inventors: Martin Langhammer, Dongdong Chen, Kevin Hurd
  • Publication number: 20210201071
    Abstract: According to implementations of the subject matter described herein, there is provided an image colorization solution. The solution includes determining a similarity between contents presented in a grayscale source image and a color reference image and determining a col or target image corresponding to the source image based on the similarity. Specifically, a first and a second sets of blocks similar and dissimilar to the reference image are determined based on the similarity; a first color for the first set of blocks is determined based on a color of corresponding blocks in the reference image; a second color for the second set of blocks is determined independently of the reference image. Through this solution, it is possible to provide user controllability and customized effects in colorization, and there is no strict requirement on correspondence between the color image and grayscale image, achieving more robustness to selection of color reference images.
    Type: Application
    Filed: June 19, 2019
    Publication date: July 1, 2021
    Inventors: Jing LIAO, Lu YUAN, Dongdong CHEN, Mingming HE
  • Publication number: 20210182022
    Abstract: The present disclosure describes a digital signal processing (DSP) block that includes a plurality of columns of weight registers and a plurality of inputs configured to receive a first plurality of values and a second plurality of values. The first plurality of values is stored in the plurality of columns of weight registers after being received. Additionally, the DSP block includes a plurality of multipliers configured to simultaneously multiply each value of the first plurality of values by each value of the second plurality of values.
    Type: Application
    Filed: June 26, 2020
    Publication date: June 17, 2021
    Inventors: Martin Langhammer, Dongdong Chen, Jason R. Bergendahl
  • Publication number: 20210182023
    Abstract: The present disclosure describes a digital signal processing (DSP) block that includes a plurality of columns of weight registers and a plurality of inputs configured to receive a first plurality of values and a second plurality of values. The first plurality of values is stored in the plurality of columns of weight registers after being received. Additionally, the DSP block includes a plurality of multipliers configured to simultaneously multiply each value of the first plurality of values by each value of the second plurality of values.
    Type: Application
    Filed: June 26, 2020
    Publication date: June 17, 2021
    Inventors: Martin Langhammer, Dongdong Chen, Jason R. Bergendahl
  • Patent number: 11021478
    Abstract: This invention relates to indolizine derivatives and their use in medicine. In particular, the present invention discloses novel substituted indolizine derivatives of formula I, or an isotopically labeled compound thereof, or an optical isomer thereof, a geometric isomer thereof, a tautomer thereof or a mixture of various isomers, or a pharmaceutically acceptable salt thereof, or a prodrug thereof. The invention also relates to the use of these compounds in medicine.
    Type: Grant
    Filed: May 8, 2018
    Date of Patent: June 1, 2021
    Assignee: KIND PHARMACEUTICAL
    Inventors: Dong Liu, Dongdong Chen, Biao Deng, Xiangyun Tu, Zinan Fang, Haohao Wu, Danyan Gu
  • Patent number: 10970042
    Abstract: An integrated circuit with specialized processing blocks is provided. A specialized processing block may be optimized for machine learning algorithms and may include a multiplier data path that feeds an adder data path. The multiplier data path may be decomposed into multiple partial product generators, multiple compressors, and multiple carry-propagate adders of a first precision. Results from the carry-propagate adders may be added using a floating-point adder of the first precision. Results from the floating-point adder may be optionally cast to a second precision that is higher or more accurate than the first precision. The adder data path may include an adder of the second precision that combines the results from the floating-point adder with zero, with a general-purpose input, or with other dot product terms. Operated in this way, the specialized processing block provides a technical improvement of greatly increasing the functional density for implementing machine learning algorithms.
    Type: Grant
    Filed: September 27, 2018
    Date of Patent: April 6, 2021
    Assignee: Intel Corporation
    Inventors: Martin Langhammer, Dongdong Chen, Kevin Hurd