Patents by Inventor Dorothea Reilly

Dorothea Reilly has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Antibodies with altered effector functions
    Publication number: 20050152894
    Abstract: The invention provides antibodies with altered effector functions, and methods of using these antibodies in the treatment of various diseases. The invention further provides compositions, kits and articles of manufacture for practicing methods of the invention.
    Type: Application
    Filed: September 3, 2004
    Publication date: July 14, 2005
    Inventors: Lynne Krummen, Dorothea Reilly, Stefanie Weikert
  • Methods and compositions for increasing antibody production
    Publication number: 20050048572
    Abstract: The invention provides methods and compositions for improved expression and production of recombinant antibodies in host cell expression systems. In particular, prokaryotic expression and production of antibodies with modified hinge cysteine residues are provided. The invention further provides compositions, kits and articles of manufacture for practicing methods of the present invention.
    Type: Application
    Filed: October 30, 2003
    Publication date: March 3, 2005
    Inventors: Dorothea Reilly, Daniel Yansura
  • Process for production of polypeptides
    Publication number: 20030109024
    Abstract: Vectors for producing polypeptides heterologous to prokaryotes are described comprising, along with the polypeptide-encoding nucleic acid, anti-termination nucleic acid that inhibits intragenic transcription termination with a non-lambda promoter therefor and/or nucleic acid encoding a GreA or GreB protein and a promoter therefor. Also described are processes for producing a heterologous polypeptide in prokaryotic host cells utilizing such elements to improve the quality and/or quantity of heterologous polypeptide produced.
    Type: Application
    Filed: February 22, 2002
    Publication date: June 12, 2003
    Applicant: GENENTECH, INC.
    Inventors: Eriks Sasha Paegle, Dorothea Reilly, Daniel G. Yansura
  • Prokaryotically produced antibodies and uses thereof
    Publication number: 20030073164
    Abstract: The present invention provides methods and compositions for improved expression and production of recombinant antibodies in prokaryotic expression systems. Particularly contemplated are prokaryotic expression and production of full length aglycosylated antibodies. The antibody products of the invention can be used in various aspects of biological research, diagnosis and medical treatment.
    Type: Application
    Filed: December 13, 2001
    Publication date: April 17, 2003
    Applicant: GENENTECH, INC.
    Inventors: Laura C. Simmons, Laura Klimowski, Dorothea Reilly, Daniel G. Yansura