Abstract: A urinal assembly having a frame and a plurality of posts or posts extending from the frame. The frame can include a plurality of openings. The openings can be defined by a plurality of sides and corners. The posts can extend from the corners and/or from the sides of the openings. In some embodiments, posts extend from a first face and a second face of the frame.

Abstract: A compound of Formula (I), or a pharmaceutically acceptable salt thereof, is provided that has been shown to be useful for treating a BRM-mediated and/or BRG1-mediated disease or disorder: Formula (I) wherein R1 through R6 are as defined herein.

Abstract: The present invention relates to compounds of formula I: in which p, q, Y1, Y2, R1, R2a, R2b, R3a, R3b, R4a, R4b, R5a, R5b, R7 and R8 are defined in the Summary of the Invention; capable of inhibiting the activity of SHP2. The invention further provides a process for the preparation of compounds of the invention, pharmaceutical preparations comprising such compounds and methods of using such compounds and compositions in the management of diseases or disorders associated with the aberrant activity of SHP2.

Abstract: A tissue fastening device includes a body including a plurality of sidewalls defining a channel, an anvil having a proximal end and a distal end and pivotally coupled to the body and the anvil moves between an open position and a closed position, and a locking mechanism to lock the anvil in the closed position.

Abstract: A lightweight vehicle includes a pair of rear wheel assemblies, one or more front wheel assemblies, a universal assembly platform, and forward facing seating. The universal assembly platform includes a planar main vehicle chassis, a front suspension system connected to the planar main vehicle chassis and to which the one or more front wheel assemblies is mounted, and a rear suspension system connected to the planar main vehicle chassis and to which the pair of rear wheel assemblies is mounted. A front distal end of the one or more front wheel assemblies is longitudinally forward of a front end of the planar main vehicle chassis. The forward facing seating is mounted to the planar main vehicle chassis such that a portion of a seat bottom of the forward facing seating is located longitudinally rearward of an axis extending through a center of the pair of rear wheel assemblies.

Abstract: A nanofiber comprising a polyamide including at least one substituted phenyl group is provided. The nanofiber includes an average diameter from about 50 to about 1000 nm. A fibrous mat including a plurality of the nanofibers is also provided. A composite including a plurality of the nanofibers and a continuous matrix resin is also provided. A method of forming the nanofibers is also provided.

Abstract: A lightweight vehicle includes a pair of rear wheel assemblies, one or more front wheel assemblies, a universal assembly platform, and forward facing seating. The universal assembly platform includes a main vehicle chassis, a front suspension system coupled to the main vehicle chassis and to which the one or more front wheel assemblies is mounted, and a rear suspension system coupled to the main vehicle chassis and to which the pair of rear wheel assemblies is mounted. A front distal end of the one or more front wheel assemblies is longitudinally forward of a front end of the main vehicle chassis. The forward facing seating is mounted to the main vehicle chassis such that a portion of a seat bottom of the forward facing seating is located longitudinally rearward of an axis extending through a center of the pair of rear wheel assemblies.

Abstract: A lightweight vehicle includes a first wheel assembly including a first wheel rotatable about an axis, a second wheel assembly including a second wheel rotatable about the axis, a platform including a chassis and a rear suspension assembly coupling the first wheel assembly and the second wheel assembly to the chassis, a first seat coupled to the chassis, and a second seat coupled to the chassis rearward of the first seat. At least a portion of the chassis has a planar shape. The second seat includes a bottom and a back. The back is positioned rearward of at least a portion of the bottom such that the second seat defines a forward-facing seating. At least a portion of the bottom of the second seat is positioned longitudinally rearward of a plane extending vertically upward from the axis about which the first wheel and the second wheel are rotatable.

Abstract: A test and measurement system includes a test and measurement device, a connection to allow the test and measurement device to connect to an optical transceiver, and one or more processors, configured to execute code that causes the one or more processors to: set operating parameters for the optical transceiver to reference operating parameters; acquire a waveform from the optical transceiver; repeatedly execute the code to cause the one or more processors to set operating parameters and acquire a waveform, for each of a predetermined number of sets of reference operating parameters; build one or more tensors from the acquired waveforms; send the one or more tensors to a machine learning system to obtain a set of predicted operating parameters; set the operating parameters for the optical transceiver to the predicted operating parameters; and test the optical transceiver using the predicted operating parameters.

Abstract: Systems and methods for providing a container network interface (CNI) specification that has been modified with a set of annotations, a set of operations, and a set of policies to provide network configuration reuse, network configuration replication, and database management (garbage collection) functionality are described. In response to receiving a request to initiate a function, whether the function is to be reused or replicated may be determined. In response to determining that the function is to be reused, calling a container network interface (CNI) plugin with a first operation that decouples database functions from network functions, so that the database can cache and reuse a network configuration generated for the function. In response to determining that the function is to be replicated, calling the CNI plugin with a second operation to create the network configuration and generate and store a template of the network configuration in the database.

Abstract: A test and measurement device has a connection to allow the test and measurement device to connect to an optical transceiver, one or more processors, configured to execute code that causes the one or more processors to: initially set operating parameters for the optical transceiver to average parameters, acquire a waveform from the optical transceiver, measure the acquired waveform and determine if operation of the transceiver passes or fails, send the waveform and the operating parameters to a machine learning system to obtain estimated parameters if the transceiver fails, adjust the operating parameters based upon the estimated parameters, and repeat the acquiring, measuring, sending, and adjusting as needed until the transceiver passes.

Abstract: A method of operating a vehicle climate system when an ambient temperature is below a threshold temperature is provided. In response to an ambient temperature being less than a threshold temperature, a controller is adapted to operate a blower motor at a voltage that depends on whether the vehicle is in charge sustain mode or charge deplete mode. In response to an ambient temperature being greater than a threshold temperature, the controller is adapted to operate the blower motor at a voltage that does not depend on whether in the charge sustain or charge deplete modes.

Abstract: In various representative aspects, a fish tank or aquarium filter assembly system that utilizes a plurality of stacked and compressed disc filters with a plurality of cross-sectional grooves for filtering debris in the fish tank. The exemplary embodiment in this invention offers an improvement over existing systems and methods for among others for eliminating the need to use common fabrics such as socks as the filtering technique, and utilizing the pattern of grooves on the disc filters to be arranged in a pattern that filters debris in a more efficient manner than existing filters.

Abstract: The present invention provides methods and compositions for the stimulation of immune responses and for treating or preventing allergic disease and responses and inflammatory disease and responses. In particular, the present invention provides nanoemulsion compositions and methods of using the same for the induction of immune responses that prevent or treat allergic disease by reducing allergic response. Compositions and methods of the invention find use in, among other things, clinical (e.g. therapeutic and preventative medicine (e.g., vaccination)) and research applications.

Abstract: The present invention relates to compounds of formula I: in which Y1, Y2, R1, R2 and R3 are defined in the Summary of the Invention; capable of inhibiting the activity of SHP2. The invention further provides a process for the preparation of compounds of the invention, pharmaceutical preparations comprising such compounds and methods of using such compounds and compositions in the management of diseases or disorders associated with the aberrant activity of SHP2.

Abstract: In a packaging material that is, or includes, a laminate, the laminate includes first and second webs that are joined to one another. The first web includes a metallic layer on a second layer. The metallic layer is positioned between the second layer and the second web. Indicium is defined in at least the metallic layer. The packaging material is configured so that the indicium is visible from a first side of the packaging material, and the indicium is typically not visible from a second side of the packaging material. The indicium can be at least partially defined by holes in the metallic layer. The visibility of the indicium may be enhanced by the laminate including material that is a different color than the metallic layer, and the different color being at least partially visible through the indicium.

Abstract: A test and measurement system includes a test and measurement instrument configured to receive waveform data from a device under test (DUT) on a manufacturing line, a machine learning system connected to the test and measurement instrument, and one or more processors configured to execute code that causes the one or more processors to: collect optimal tuning parameter data sets from the DUT after the DUT is tuned on the manufacturing line, determine one or more parameter data sets from the optimal tuning parameter data, load the one or more parameter data sets into the DUT, collect waveform data from the DUT for the one or more parameter data sets as training data sets, train the machine learning system using the training data sets, and use the machine learning system after training to produce an output related to the DUT.

Abstract: A system and method for relieving pressure from a passenger cabin of an aircraft during a decompression event with a resettable decompression system. The system includes a resettable decompression retainer having a swing arm pivotably connected to a base. The swing arm has a bias relative to the base provided by a spring connected to both the swing arm and the base. The swing arm engages a slip fitting that is attached to a ceiling panel of the aircraft. The resettable decompression system allows the ceiling panel to move thus allowing air pressures between a passenger cabin and a crown space to equalize. After a decompression event, the resettable decompression retainer can be manually reset without the use of tools and without repairing or replacing the resettable decompression retainer.

Abstract: The present disclosure generally relates to finding genome rearrangements from sequencing data. DNA sequence analysis systems and methods directed to identifying all sequence variants in a genome are described herein. Such systems and methods demonstrate distinct and improved features relating to the accuracy and speed with which all sequence variants in a genome are identified.