Abstract: A positron emission tomography (PET) data processing method comprises obtaining PET data from a PET detector, wherein the PET detector comprises an array of detector elements, and wherein the PET data is representative of a PET measurement of at least part of a subject. The method comprises identifying in the PET data a plurality of paired events, wherein each paired event comprises a first photon event in a first region of the PET detector and a second photon event in a second region of the PET detector. The first photon event comprises an energy deposition in a first detector element of the array or in a first detection region of the first detector element due to a scattering of a first photon at a first azimuthal scattering angle and an associated energy deposition by the scattered first photon in a second detector element of the array or in a second detection region of the first detector element or of the second detector element.

Abstract: A method and apparatus for controlling positioning of an agricultural implement relative to the ground is disclosed. The method involves receiving first and second position signals representing respective first and second positions of the agricultural implement relative to the ground and providing input to a controller for controlling the positioning of the agricultural implement. The method involves receiving an intermediate position signal representing an intermediate position of the agricultural implement and being associated with an intermediate location between locations respective first and second positions.

Abstract: An environmentally friendly puncture sealing composition is provided which includes natural rubber latex, suitably high filtered natural rubber latex having a controlled particle size, and an aqueous antifreeze agent that includes water, glycerin and propylene glycol. The aqueous antifreeze agent has a viscosity profile similar to common ethylene glycol-based antifreeze agents, but is free of ethylene glycol. The puncture sealing composition avoids the environmental hazards of ethylene glycol, and is effective at temperatures of ?30° C. and lower.

Abstract: The present invention relates to compounds of formula I: in which p, q, Y1, Y2, R1, R2a, R2b, R3a, R3b, R4a, R4b, R5a, R5b, R7 and R8 are defined in the Summary of the Invention; capable of inhibiting the activity of SHP2. The invention further provides a process for the preparation of compounds of the invention, pharmaceutical preparations comprising such compounds and methods of using such compounds and compositions in the management of diseases or disorders associated with the aberrant activity of SHP2.

Abstract: Embodiments provide a computer implemented method, in a data processing system comprising a processor and a memory comprising instructions which are executed by the processor to cause the processor to implement a full question generation system, the method comprising ingesting a query dataset derived from one or more search queries entered by one or more users of an internet search engine; identifying questions from the ingested query dataset; separating one or more prior full questions from the ingested dataset; identifying one or more question intent queries from the query dataset; for each identified question intent query; sorting the question intent query into one or more bins based on one or more missing interrogative words; and appending the missing interrogative word and a verb onto the question intent query to generate a full question. The full question generation method can additionally generate un-canonical questions.

Abstract: The present application relates to immunogenic compositions comprising a mixture of Bordetella (e.g., B. pertussis) antigens and an oil in water nanoemulsion. In particular, the invention provides immunogenic compositions comprising nanoemulsion and a combination of Bordetella (e.g., B. pertussis) antigens that have different functions, for example, combinations including B. pertussis adherence factors (adhesins), B. pertussis toxins or B. pertussis virulence factors. Vaccines, methods of treatment, uses of and processes to make a pertussis or whooping cough vaccine are also described. Compositions and methods of the present invention find use in, among other things, clinical (e.g. therapeutic and preventative medicine (e.g., vaccination)) and research applications.

Abstract: Embodiments provide a computer implemented method, in a data processing system comprising a processor and a memory comprising instructions which are executed by the processor to cause the processor to implement a full question generation system, the method comprising ingesting, into the full question generation system, a query dataset derived from one or more search queries entered by one or more users of an internet search engine; identifying questions from the ingested query dataset; separating, through a full question identification module, one or more prior full questions from the ingested dataset; identifying, through a question intent query identification module, one or more question intent queries from the query dataset; for each identified question intent query: sorting, through a sorting module, the question intent query into one or more bins based on one or more missing interrogative words; and appending, through an appending module, the missing interrogative word and a verb onto the question intent

Abstract: Systems and methods for the display and navigation of a social network are set forth. According to one embodiment, a method comprising identifying a first profile in a social network, identifying associated profiles associated with the first profile, ranking the associated profiles, wherein ranking is not based exclusively on a degree of separation, and outputting the associated profiles based at least in part on the ranking is set forth. According to another embodiment, a method comprising identifying a user profile, identifying a member profile, determining an association path for the user profile and the member profile, and outputting the association path is set forth.

Abstract: A computer-implemented method according to one embodiment includes identifying a first group of textual data, determining a plurality of word combinations within the first group of textual data, and determining a first plurality of key words for the first group of textual data, utilizing the plurality of word combinations.

Abstract: A processing apparatus includes floating point arithmetic circuitry coupled to monitoring circuitry. The monitoring circuitry stores exponent limit data indicating at least one of a maximum exponent value and a minimum exponent value processed when performing the floating point arithmetic operations. The monitoring circuitry may be selectively enabled in dependence upon a virtual machine identifier, an application specific identifier or a program counter value range. Exponent limit data may be gathered in respect of different portions of the floating point arithmetic circuitry and/or may be aggregated to form global exponent limit data for the system.

Abstract: Embodiments provide a system and method for semantic distance calculation. The method can involve ingesting a plurality of documents; extracting a set of subjects from the plurality of documents using latent dirichlet allocation; for each document in the plurality of documents, generating a classification list comprising a ranking of the one or more subjects based on the relevance of each subject to the document; for each classification list, calculating the semantic distance between each subject present on the classification list; aggregating the plurality of classification lists; and creating a distance matrix containing the relative semantic distances between each member of the set of subjects.

Abstract: Embodiments provide a system and method for semantic distance calculation. The method can involve receiving a plurality of documents having a set of subjects extracted through the use of latent dirichlet allocation; for each document in the plurality of documents, generating a classification list comprising a ranking of the one or more subjects based on the relevance of each subject to the document; for each classification list, calculating the semantic distance between each subject present on the classification list; aggregating the plurality of classification lists; and creating a distance matrix containing the relative semantic distances between each member of the set of subjects.

Abstract: A method of minimizing data storage medium fragmentation, wherein the method provides a data storage library comprising (N) data storage media, wherein (N) is greater than or equal to 1. The method establishes a threshold fragmentation index, and determines, for each value of (i), an actual fragmentation index for an (i)th data storage medium, wherein (i) is greater than or equal to 1 and less than or equal to (N). The method receives a data set from a host computer in communication with the data storage library, and writes the data set to an (i)th data storage medium based upon an (i)th actual fragmentation index.

Abstract: A data processing apparatus is disclosed that comprises monitoring circuitry for monitoring accesses to a plurality of addressable locations within said data processing apparatus that occur between start and end events said monitoring circuitry comprising: an address location store for storing data identifying said plurality of addressable locations to be monitored and a monitoring data store; said monitoring circuitry being responsive to detection of said start event to detect accesses to said plurality of addressable locations and to store monitoring data relating to a summary of said detected accesses in said monitoring data store; and said monitoring circuitry being responsive to detection of said end event to stop collecting said monitoring data; said monitoring circuit being responsive to detection of a flush event to output said stored monitoring data and to flush said monitoring data store.

Abstract: Methods for producing a paired tag from a nucleic acid sequence are provided in which the paired tag comprises the 5? end tag and 3? end tag of the nucleic acid sequence. In one embodiment, the nucleic acid sequence comprises two restriction endonuclease recognition sites specific for a restriction endonuclease that cleaves the nucleic acid sequence distally to the restriction endonuclease recognition sites. In another embodiment, the nucleic acid sequence further comprises restriction endonuclease recognition sites specific for a rare cutting restriction endonuclease. Methods of using paired tags are also provided. In one embodiment, paired tags are used to characterize a nucleic acid sequence. In a particular embodiment, the nucleic acid sequence is a genome. In one embodiment, the characterization of a nucleic acid sequence is karyotyping. Alternatively, in another embodiment, the characterization of a nucleic acid sequence is mapping of the sequence.

Abstract: A system includes an alternator having a field coil and a plurality of output windings, a field current controller configured to receive an AC input and convert the AC input into a regulated DC output that is supplied to the field coil of the alternator, and a controller configured to monitor at least one operating parameter of the field current controller and to compare a monitored value of the at least one operating parameter to a threshold range.

Abstract: A computer-implemented method according to one embodiment includes identifying a first group of textual data, determining a plurality of word combinations within the first group of textual data, and determining a first plurality of key words for the first group of textual data, utilizing the plurality of word combinations.

Abstract: An article of footwear having an adjustable width is disclosed. The article of footwear can include a lower sole and an upper sole. The lower and upper soles can have grooves to allow for expansion and contraction. The article of footwear can also include a width adjustment assembly. The width adjustment assembly can have a lead screw, an adjustment device accessible to a wearer from the outside of the article of footwear, an actuation strap, an anchor plate connected to the actuation strap. Rotation of the adjustment device can cause the lead screw to rotate, which in turn can change the tension in the actuation strap. Changes to the tension in the actuation strap can cause the width of the forefoot portion of an article of footwear to be adjusted.

Abstract: A data processing system is provided with processing circuitry as well as a bank of 64-bit registers. An instruction decoder decodes arithmetic instructions and logical instruction specifying arithmetic operations and logical operations to be performed upon operands stored within the 64-bit registers. The instruction decoder is responsive to an operand size field SF within the arithmetic instructions and the logical instructions specifying whether the operands are 64-bit operands or 32-bit operands where all of the operands are 64-bit operands or all of the operands are 32-bit operands. If a switch is made to a lower exception level, then a check is made as to whether or not a register being used was previously subject to a 64-bit write to that register. If such a 64-bit write had previously taken place, then the upper 32-bits are flushed so as to avoid data leakage from the higher exception level.

Abstract: A single piece gasket is disclosed having a skeletal member, typically metallic, and a pliable body. The pliable body includes a first portion having a first firmness and a second perimeter portion have a firmer consistency. When such a composite body is placed under compression, the perimeter will tend to limit the flow of the softer inner material past the firmer perimeter region or portion of the gasket. In this manner, creep or overrun of the less firm portion material will be reduced.