Abstract: Aspects of this invention include the use of G-2MePE to treat patients with brain injury characterized by non-convulsive seizures. G-2MePE is useful in treating brain injuries caused by traumatic brain injury, stroke, hypoxia/ischemia and toxic injury.

Abstract: An adhesive label is configured to be wrapped around an apparatus and to outline a predetermined image having first and second components. A first facestock has opposite first and second edges that come into proximity with one another when the label is wrapped around the apparatus. The first edge includes first contours that outline the first component of the predetermined image, and the second edge includes second contours that outline the second component. A multilayer sheet assembly comprises the adhesive label, wherein the first facestock inner surface includes a lined portion that is covered by a release liner, and an unlined portion that is not covered by the release liner. The sheet assembly further comprises a second facestock that covers at least some of the unlined portion of the first facestock inner surface, and is adhered thereto using an adhesive.

Abstract: A label sheet assembly is provided with bar code information thereon defining the layout of the labels on the backing sheet. A versatile label dispenser apparatus advances the label sheets and deflects them over a peeling bar in one direction to partially separate the labels from the backing sheet; with the advancing action being determined by the bar code information. The label sheet assemblies are then deflected in the opposite direction, and are routed in a substantially flat condition to the output of the dispenser apparatus. The labels are partially dispensed, substantially vertically from the dispenser, and a substantial number of sensors are provided to sense when all of the labels have been removed; and then the dispenser advances the label sheet assembly to partially dispense the next row of labels. The bar code reader may also sense the leading edge of the label sheet assembly to accurately control the incremental advancing of the label sheet assembly.

Abstract: A media sheet which can be a label sheet assembly is provided with bar code information thereon defining the layout of the labels on the backing sheet, and/or a validation symbol or mark. A sheet feeding mechanism which may be part of a label peeler has at least one sensor which reads the encoded information and/or the validation symbol, and either takes an action with respect to the sheet, does not take the action, or takes a different action with respect to the sheet depending on the encoding or symbol on the sheet. The actions can include advancing the label sheet according to the layout of labels on the sheet, dispensing labels depending on the presence of a validation code, or other actions.

Abstract: An advertising device is provided having a bumper sticker assembly and an insulation assembly. The bumper sticker assembly has a first side that is semi-resistant to adhesives and a second side having an adhesive applied thereto. The insulation assembly has a flexible, planar insulation member and a panel of release material coupled thereto. Prior to use, or for storage, the advertising device is kept flat with the bumper sticker assembly releasably coupled to said release material. The advertising device may be used as a cup holder by removing a portion of the insulation assembly, thereby exposing a strip of adhesive, wrapping the advertising device around a container and adhering the strip to the bumper sticker assembly first side. Alternatively, the entire insulation assembly may be removed and the bumper sticker assembly may be used as a traditional bumper sticker.

Abstract: An advertising device is provided having a bumper sticker assembly and an insulation assembly. The bumper sticker assembly has a first side that is semi-resistant to adhesives and a second side having an adhesive applied thereto. The insulation assembly has a flexible, planar insulation member and a panel of release material coupled thereto. Prior to use, or for storage, the advertising device is kept flat with the bumper sticker assembly releasably coupled to said release material. The advertising device may be used as a cup holder by removing a portion of the insulation assembly, thereby exposing a strip of adhesive, wrapping the advertising device around a container and adhering the strip to the bumper sticker assembly first side. Alternatively, the entire insulation assembly may be removed and the bumper sticker assembly may be used as a traditional bumper sticker.

Abstract: A fully dense, high thermal conductivity graphite can be manufactured in a single hot-pressing step, without the need for multiple re-impregnation and baking steps as required in the standard processes. The ingredients of the blend, namely graphite filler which may or may not be reduced in size, and a binder, are dry mixed at room temperature, below the melting point of the binder, avoiding the requirement to maintain the binder at an elevated temperature prior to mixing.

Abstract: A process and apparatus for producing signals for controlling a display to produce an image in an imaging system employing a plurality of transducers. First and second beam signals are produced in response to delayed channel signals associated with respective transducers, the delayed channel signals representing real and imaginary components of time domain signals associated with respective transducers suitably delayed to focus a receive beam pattern of the transducers at a beam angle, each of the first and second beam signals including separate real and imaginary component representations. The real and imaginary components of the first and second beam signals are combined to produce a composite beam signal, the composite beam signal including separate real and imaginary component representations.

Abstract: A method and apparatus for producing an amplitude value for use in controlling illumination of a pixel on a display, in response to a sampled sonar signal produced by an element of a sonar array. A pixel time associated with the pixel is found, the pixel time representing a time required for sound to travel a distance represented by the pixel, according to a range of distance to be viewed on the display. A sample point of the sampled sonar signal is then found, the sample point having a sample time nearest the pixel time. A delay value associated with the pixel is then found, the delay value including an array element delay value. A representation of a synthesized waveform is then produced, in response to the sonar signal, the representation comprising a plurality of sample points coinciding in time with the sample points of the sonar signal.

Abstract: Printing stock for use in making a sign that includes a face sheet and a backing sheet. The sign is formed, for example, by overlapping a plurality of sheets of the printing stock, with the sheets arranged in a pattern to form a desired image of the sign. In a number of embodiments, the sheets of printing stock may be received through and printed on by a small-office, home-office (SOHO) printer. In other embodiments, the sheets of printing stock are of standard size for use with SOHO printers, i.e., A4, 8½×11 inches, and legal size. The face sheet includes a printing surface for receiving ink and an adhesive surface for receiving the backing sheet. The face includes a face cut forming a margin and a face sub-sheet such that at least a portion of the margin is separable from the face sub-sheet.

Abstract: A novel football field grille is disclosed. The novel football field grill includes a firebox; a retractable lid mounted on the firebox, capable of retracting from a first closed position to a second open position; a hollow goalpost, having a first end and a second end, the first end of the goalpost mounted on the retractable lid, and the second end of the hollow goalpost in fluid communication with the firebox when the retractable lid is in the first closed position; and a support leg, mounted to the firebox to engage a surface.

Abstract: Protein tyrosine phosphatases (PTPases) such as PTP1B can play a role in regulating a wide variety of cellular responses such as insulin signaling. Substituted bicyclic fused-thiophene compounds can inhibit PTP1B and thereby induce greater insulin sensitivity. Accordingly, PTP1B inhibition can provide an alternate treatment for PTPase-mediated disorders such as diabetes.

Abstract: Protein tyrosine phosphatases (PTPases) such as PTP1B can play a role in regulating a wide variety of cellular responses such as insulin signaling. Substituted thiophene compounds such as, for example, 2-carboxyl, 3-carboxymethoxy, 5-aryl substituted thiophenes, can inhibit PTP1B and thereby induce greater insulin sensitivity. Accordingly, PTP1B inhibition can provide an alternate treatment for PTPase-mediated disorders such as diabetes.

Abstract: An apparatus for measuring an operating parameter of a relay armature operating a pair of relay contacts, and for controlling the voltage that occurs between the pair of relay contacts when they open or close. The apparatus includes a microcontroller that senses a reference voltage, and a sensed voltage signal that comprises a voltage component representing a relay coil voltage, a power supply voltage component, and a voltage component induced by a motion of the armature. The microcontroller uses discrete digital samples of the signals to deduce the operating parameter. The microcontroller provides a control signal to cause the relay to open or close the relay contacts at a time when a predefined voltage occurs therebetween. The predefined voltage can be substantially zero volts. Methods of use of the apparatus to control the opening and closing of relay contacts are described.

Abstract: Apparatus and method for use in the sterile sampling of liquid from a container, the apparatus having a normally vertical tubular sight chamber coupled by its lower end to a sample port assembly. The upper end of the chamber is fitted with an inlet tube through which sample liquid can be received and a filtered vent to allow air to flow to and from the sight chamber while preventing the ingress of bacteria in to the chamber. The sample port assembly has a tubular body encasing a sheathed needle assembly so that evacuated phials can be inserted into the body and pressed onto the needle assembly to withdraw samples of liquid collected in the sight chamber, the sight chamber preferably having transparent walls that are marked with graduations so that each phial can be withdrawn from the needle assembly after the desired amount of liquid has been collected.

Abstract: The invention dynamically produces alternate referrer pages substantially similar to pages previously viewed, through a web browser, by a visitor who linked to a target web page via a link on the previously viewed pages. When the browser links to the target page, a referrer URL is obtained for the referrer page from which the browser loaded the target page. The referrer URL is stored in a queue. The queue is inspected regularly. If the queue contains an unexamined entry, a request for that entry's referrer URL is executed to obtain the alternate referrer pages. The IP address of the computer running the browser is used to derive a country code corresponding to the IP address. The referrer URL request can be issued through a computer in a geographic region corresponding to the country code so that geographic biasing of the previously viewed pages will be reflected in the alternate pages.

Abstract: It is most desirable that the registry files of a local computer platform be in instant synchronism with the registry files of a remote backup computer platform. The present invention provides a component object that can monitor a user-specified registry key on a local computer platform and operate to duplicate that registry key, on an instant update basis, at the remote backup platform whenever the local registry key undergoes a change.

Abstract: The invention relates to a process for simultaneously N(2)-acylating piperazic acid or an ester thereof and forming a bicyclic ring structure. The invention also relates to the use of that process step in a method of synthesizing a bicyclic compound useful as an intermediate for the production of an inhibitor of a caspase, particularly an inhibitor of interleukin-1&bgr; converting enzyme (“ICE”).