Patents by Inventor Douglas Fraser

Douglas Fraser has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240086522
    Abstract: Thread information generated by one or more computing systems is captured. A thread pattern is identified from the captured thread information. The thread pattern is compared to a learned thread pattern. An anomaly is identified in the thread pattern based on a variance from the learned thread pattern. In response to identifying the anomaly in the thread pattern, an action is taken based on the anomalous thread pattern. For example, a user may be notified. The thread patterns may be extended to compare between operating systems, hypervisors, containers, and/or virtual machines.
    Type: Application
    Filed: September 9, 2022
    Publication date: March 14, 2024
    Applicant: MICRO FOCUS LLC
    Inventors: Douglas Max Grover, MICHAEL F. ANGELO, MARTIN FRASER ARLITT
  • Publication number: 20230338310
    Abstract: The invention relates to the use of compounds, and compositions comprising such compounds, for treating viral infection. More specifically, the compounds for use in the invention are comprised of structural formula (1), or a pharmaceutically acceptable salt thereof. The invention also relates to the compounds for use in treating hyperinflammation.
    Type: Application
    Filed: May 25, 2021
    Publication date: October 26, 2023
    Inventors: Deborah O'NEIL, Douglas FRASER-PITT
  • Publication number: 20230152317
    Abstract: Methods of diagnosing COVID-19 infection in a subject comprising: (a) obtaining a test sample from the subject (b) comparing levels of a biomarker in the test sample with known normal reference levels of the biomarker, wherein an increase in the level f the biomarker in the test sample relative to the known reference levels of the biomarker is indicative of COVID-19 diagnosis in the subject, the biomarker being one or more of granzyme B, tumor necrosis factor (TNF), heat shock protein 70 (HSP70), interleukin-18 (IL-18), interferon-gamma-inducible protein 10 (IP-10) and elastase 2. These biomarkers are used as therapeutic targets for COVID-19 infection. Also, methods that serve to prognosticate the outcome, recovery and disease severity of COVID-19 patients.
    Type: Application
    Filed: April 17, 2021
    Publication date: May 18, 2023
    Applicant: LONDON HEALTH SCIENCES CENTRE RESEARCH INC.
    Inventors: Douglas Fraser, Gediminas Cepinskas, Mark Daley
  • Publication number: 20230135443
    Abstract: A method of diagnosing acquired CNS injury (ACNSI) in a subject comprising: (a) obtaining a test sample from the subject (b) comparing levels of a lipid species or a cohort of multiple lipid species in the test sample with the levels of the single lipid species or the cohort of multiple lipid species in a control sample, or comparing to a normal reference range, (i.e. non-ACNSI (referred to as “normal”) subjects) using quantitative measurements, wherein a change (i.e. a drop or an increase) in the level of the lipid species or the cohort of multiple lipid species in the test sample relative to the control sample is indicative of ACNSI in the subject.
    Type: Application
    Filed: March 11, 2021
    Publication date: May 4, 2023
    Applicant: LONDON HEALTH SCIENCES CENTRE RESEARCH INC.
    Inventor: Douglas FRASER
  • Patent number: 11446006
    Abstract: An ultrasonic diagnostic imaging system for shear wave measurement transmits push pulses into tissue for the generation of shear waves. Characteristics of the shear waves such as their velocity of passage through the tissue are measured to assess properties such as tissue stiffness. The measurements are compensated for effects of background motion by sampling echo signals from the tissue at different times and comparing the samples to detect the presence of relative motion between the ultrasound probe and the region of interest where shear waves are detected. Sensed background motion is used to adjust measured shear wave characteristics.
    Type: Grant
    Filed: October 29, 2019
    Date of Patent: September 20, 2022
    Assignee: KONINKLIJKE PHILIPS N.V.
    Inventors: John Douglas Fraser, Hua Xie
  • Patent number: 10960194
    Abstract: An apparatus for ultrasound irradiation of a body part (208) includes a first ultrasound transducer (216), and a second ultrasound transducer (212) mounted oppositely, and is configured: a) such that at least two ultrasound receiving elements, for determining a relative orientation of the first to the second transducer, are attached to the first transducer; b) for a beam, from the first transducer, causing cavitation, and/or bubble destruction of systemically circulating microbubbles, within the body part; or c) both with the attached elements and for the causing. The apparatus registers, with said first transducer, the second transducer, by using as a reference respectively the features a) and/or b).
    Type: Grant
    Filed: June 25, 2014
    Date of Patent: March 30, 2021
    Assignee: KONINKLIJKE PHILIPS N.V.
    Inventors: Jeffry Earl Powers, William Tao Shi, John Douglas Fraser, Ralf Seip, Francois Guy Gerard Marie Vignon
  • Patent number: 10873793
    Abstract: An apparatus for interrogating radio-frequency identification (RFID) tags within an enclosure. In an embodiment, the apparatus comprises an RFID module, a first assembly comprising a processor, a second assembly comprising an RFID radiator operatively coupled to the RFID module, and a connection element coupled to the first assembly and second assembly such that the second assembly is movable relative to the first assembly between a first configuration and second configuration. The processor may be configured to interrogate RFID tags via the RFID module and RFID radiator when the second assembly is in the second configuration, and not interrogate RFID tags when the second assembly is in the first configuration. In addition, both the first assembly and the second assembly may comprise attachment components configured to removably couple its respective assembly to one or more surfaces of an enclosure.
    Type: Grant
    Filed: September 25, 2019
    Date of Patent: December 22, 2020
    Assignee: QUAKE GLOBAL, INC.
    Inventors: Kiely Per Faroe, Christopher Lee Fennig, Gordon Douglas Fraser, Patrick J. Sweeney, II, David Vetter
  • Publication number: 20200060655
    Abstract: An ultrasonic diagnostic imaging system for shear wave measurement transmits push pulses into tissue for the generation of shear waves. Characteristics of the shear waves such as their velocity of passage through the tissue are measured to assess properties such as tissue stiffness. The measurements are compensated for effects of background motion by sampling echo signals from the tissue at different times and comparing the samples to detect the presence of relative motion between the ultrasound probe and the region of interest where shear waves are detected. Sensed background motion is used to adjust measured shear wave characteristics.
    Type: Application
    Filed: October 29, 2019
    Publication date: February 27, 2020
    Inventors: JOHN DOUGLAS FRASER, HUA XIE
  • Publication number: 20200045387
    Abstract: An apparatus for interrogating radio-frequency identification (RFID) tags within an enclosure. In an embodiment, the apparatus comprises an RFID module, a first assembly comprising a processor, a second assembly comprising an RFID radiator operatively coupled to the RFID module, and a connection element coupled to the first assembly and second assembly such that the second assembly is movable relative to the first assembly between a first configuration and second configuration. The processor may be configured to interrogate RFID tags via the RFID module and RFID radiator when the second assembly is in the second configuration, and not interrogate RFID tags when the second assembly is in the first configuration. In addition, both the first assembly and the second assembly may comprise attachment components configured to removably couple its respective assembly to one or more surfaces of an enclosure.
    Type: Application
    Filed: September 25, 2019
    Publication date: February 6, 2020
    Inventors: Kiely Per FAROE, Christopher Lee FENNIG, Gordon Douglas FRASER, Patrick J. SWEENEY, II, David VETTER
  • Patent number: 10485514
    Abstract: An ultrasonic diagnostic imaging system for shear wave measurement transmits push pulses into tissue for the generation of shear waves. Characteristics of the shear waves such as their velocity of passage through the tissue are measured to assess properties such as tissue stiffness. The measurements are compensated for effects of background motion by sampling echo signals from the tissue at different times and comparing the samples to detect the presence of relative motion between the ultrasound probe and the region of interest where shear waves are detected. Sensed background motion is used to adjust measured shear wave characteristics.
    Type: Grant
    Filed: December 8, 2011
    Date of Patent: November 26, 2019
    Assignee: KONINKLIJKE PHILIPS N.V.
    Inventors: John Douglas Fraser, Hua Xie
  • Patent number: 10484761
    Abstract: An apparatus for interrogating radio-frequency identification (RFID) tags within an enclosure. In an embodiment, the apparatus comprises an RFID module, a first assembly comprising a processor, a second assembly comprising an RFID radiator operatively coupled to the RFID module, and a connection element coupled to the first assembly and second assembly such that the second assembly is movable relative to the first assembly between a first configuration and second configuration. The processor may be configured to interrogate RFID tags via the RFID module and RFID radiator when the second assembly is in the second configuration, and not interrogate RFID tags when the second assembly is in the first configuration. In addition, both the first assembly and the second assembly may comprise attachment components configured to removably couple its respective assembly to one or more surfaces of an enclosure.
    Type: Grant
    Filed: June 30, 2017
    Date of Patent: November 19, 2019
    Assignee: QUAKE GLOBAL, INC.
    Inventors: Kiely Per Faroe, Christopher Lee Fennig, Gordon Douglas Fraser, Patrick J. Sweeney, II, David Vetter
  • Patent number: 10448924
    Abstract: An ultrasonic diagnostic imaging system for shear wave measurement transmits push pulses in the form of a sheet of energy. The sheet of energy produces a shear wavefront which is a plane wave, which does not suffer from the 1/R radial dissipation of push pulse force as does a conventional push pulse generated along a single push pulse vector. The sheet of energy can be planar, curved, or in some other two or three dimensional shape. A curved sheet of energy can produce a shear wave source which focuses into a thin line, which increases the resolution and sensitivity of the measuring techniques used to detect the shear wave effect.
    Type: Grant
    Filed: December 2, 2011
    Date of Patent: October 22, 2019
    Assignee: KONINKLIJKE PHILIPS N.V.
    Inventors: John Douglas Fraser, Roy Peterson, Jean-Luc Robert, Vijay Shamdasani, Hua Xie
  • Publication number: 20180344671
    Abstract: The present invention relates to compositions of cysteamine or a derivative thereof for use in the treatment or prophylaxis or a disease or condition associated with neutrophil elastase activity. The compositions can be administered, e.g., by inhalation, intravenously, or topically, as appropriate.
    Type: Application
    Filed: June 4, 2018
    Publication date: December 6, 2018
    Inventors: Deborah O'Neil, Douglas Fraser-Pitt
  • Patent number: 10128777
    Abstract: The present invention relates to a pre-collapsed capacitive micro-machined transducer cell (10) comprising a substrate (12) comprising a first electrode (16), a membrane (14) comprising a second electrode (18), wherein the cell has an outer region (22) where the membrane (14) is mounted to the substrate (12) and an inner region (20) inside or surrounded by the outer region (22), wherein the membrane (14) is collapsed to the substrate (12) in a first collapsed annular-shaped region (24) located within the inner region (20).
    Type: Grant
    Filed: August 22, 2017
    Date of Patent: November 13, 2018
    Assignee: KONINKLIJKE PHILIPS N.V.
    Inventors: Andrew Lee Robinson, John Douglas Fraser
  • Publication number: 20180185305
    Abstract: The present invention relates to cysteamine, cystamine, or derivatives thereof, for use in the treatment and/or prevention of infection caused by the bacterium, Mycobacterium spp., in particular Mycobacterium abscessus, or a disease or condition associated therewith.
    Type: Application
    Filed: June 6, 2016
    Publication date: July 5, 2018
    Inventors: Deborah O'NEIL, Douglas FRASER-PITT
  • Publication number: 20170348253
    Abstract: The present invention provides a sulphur-containing compound for use in the prophylaxis or treatment of an infection associated with at least one microbe or microbial strain displaying at least some degree of drug resistance. Also provided is a product comprising a first agent being a sulphur-containing compound and a second agent being an antimicrobial agent, in particular an antibiotic agent.
    Type: Application
    Filed: June 6, 2017
    Publication date: December 7, 2017
    Inventors: Deborah O'NEIL, Douglas FRASER-PITT
  • Publication number: 20170353129
    Abstract: The present invention relates to a pre-collapsed capacitive micro-machined transducer cell (10) comprising a substrate (12) comprising a first electrode (16), a membrane (14) comprising a second electrode (18), wherein the cell has an outer region (22) where the membrane (14) is mounted to the substrate (12) and an inner region (20) inside or surrounded by the outer region (22), wherein the membrane (14) is collapsed to the substrate (12) in a first collapsed annular-shaped region (24) located within the inner region (20).
    Type: Application
    Filed: August 22, 2017
    Publication date: December 7, 2017
    Inventors: Andrew Lee Robinson, John Douglas Fraser
  • Publication number: 20170311055
    Abstract: An apparatus for interrogating radio-frequency identification (RFID) tags within an enclosure. In an embodiment, the apparatus comprises an RFID module, a first assembly comprising a processor, a second assembly comprising an RFID radiator operatively coupled to the RFID module, and a connection element coupled to the first assembly and second assembly such that the second assembly is movable relative to the first assembly between a first configuration and second configuration. The processor may be configured to interrogate RFID tags via the RFID module and RFID radiator when the second assembly is in the second configuration, and not interrogate RFID tags when the second assembly is in the first configuration. In addition, both the first assembly and the second assembly may comprise attachment components configured to removably couple its respective assembly to one or more surfaces of an enclosure.
    Type: Application
    Filed: June 30, 2017
    Publication date: October 26, 2017
    Inventors: Kiely Per FAROE, Christopher Lee FENNIG, Gordon Douglas FRASER, Patrick J. SWEENEY, David VETTER
  • Patent number: 9762148
    Abstract: The present invention relates to a pre-collapsed capacitive micro-machined transducer cell (10) comprising a substrate (12) comprising a first electrode (16), a membrane (14) comprising a second electrode (18), wherein the cell has an outer region (22) where the membrane (14) is mounted to the substrate (12) and an inner region (20) inside or surrounded by the outer region (22), wherein the membrane (14) is collapsed to the substrate (12) in a first collapsed annular-shaped region (24) located within the inner region (20).
    Type: Grant
    Filed: November 5, 2012
    Date of Patent: September 12, 2017
    Assignee: KONINKLIJKE PHILIPS N.V.
    Inventors: Andrew Lee Robinson, John Douglas Fraser
  • Patent number: 9699526
    Abstract: An apparatus for interrogating radio-frequency identification (RFID) tags within an enclosure. In an embodiment, the apparatus comprises an RFID module, a first assembly comprising a processor, a second assembly comprising an RFID radiator operatively coupled to the RFID module, and a connection element coupled to the first assembly and second assembly such that the second assembly is movable relative to the first assembly between a first configuration and second configuration. The processor may be configured to interrogate RFID tags via the RFID module and RFID radiator when the second assembly is in the second configuration, and not interrogate RFID tags when the second assembly is in the first configuration. In addition, both the first assembly and the second assembly may comprise attachment components configured to removably couple its respective assembly to one or more surfaces of an enclosure.
    Type: Grant
    Filed: February 2, 2015
    Date of Patent: July 4, 2017
    Assignee: QUAKE GLOBAL, INC.
    Inventors: Kiely Per Faroe, Christopher Lee Fennig, Gordon Douglas Fraser, Patrick J. Sweeney, II, David Vetter