Patents by Inventor Douglas H. Smith

Douglas H. Smith has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 8790666
    Abstract: The present invention relates to mechanically elongated neurons and provides useful compositions, devices and methods for treating a nerve lesion using such mechanically elongated neurons.
    Type: Grant
    Filed: May 5, 2006
    Date of Patent: July 29, 2014
    Assignee: The Trustees of the University of Pennsylvania
    Inventor: Douglas H. Smith
  • Publication number: 20130238041
    Abstract: The present invention provides a device of integrated neuronal cells interfaced with an electronic device and a method of producing the same.
    Type: Application
    Filed: February 26, 2013
    Publication date: September 12, 2013
    Applicant: The Trustees of the University of Pennsylvania
    Inventors: Douglas H. Smith, Bryan Pfister, David F. Meaney
  • Patent number: 8400636
    Abstract: A method for detecting blast induced pressure changes includes exposing a material, a contained solution, a membrane-bound solution, or a photonic crystal material, having a first optical property, to a pressure wave having a blast level. A change in the first optical property to a second optical property of the exposed material, contained solution, membrane-bound solution, or photonic crystal material is determined, and the extent of change corresponds to the blast level.
    Type: Grant
    Filed: March 27, 2009
    Date of Patent: March 19, 2013
    Assignee: The Trustees of the University of Pennsylvania
    Inventors: Douglas H. Smith, Shu Yang, D. Kacy Cullen
  • Patent number: 8401635
    Abstract: The present invention provides a device of integrated neuronal cells interfaced with an electronic device and a method of producing the same.
    Type: Grant
    Filed: June 9, 2011
    Date of Patent: March 19, 2013
    Assignee: The Trustees of the University of Pennsylvania
    Inventors: Douglas H. Smith, Bryan Pfister, David F. Meaney
  • Patent number: 7972367
    Abstract: The present invention provides a device of integrated neuronal cells interfaced with an electronic device and a method of producing the same.
    Type: Grant
    Filed: August 20, 2008
    Date of Patent: July 5, 2011
    Assignee: The Trustees of the University of Pennsylvania
    Inventors: Douglas H. Smith, Bryan Pfister, David F. Meaney
  • Publication number: 20110097719
    Abstract: The invention relates to methods of diagnosing risk of amyloid ? deposition following traumatic brain injury.
    Type: Application
    Filed: December 10, 2008
    Publication date: April 28, 2011
    Applicant: THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA
    Inventors: Douglas H. Smith, William Stewart, Vicrtoria E. Johnson
  • Publication number: 20100073678
    Abstract: A method for detecting blast induced pressure changes includes exposing a material, a contained solution, a membrane-bound solution, or a photonic crystal material, having a first optical property, to a pressure wave having a blast level. A change in the first optical property to a second optical property of the exposed material, contained solution, membrane-bound solution, or photonic crystal material is determined, and the extent of change corresponds to the blast level.
    Type: Application
    Filed: March 27, 2009
    Publication date: March 25, 2010
    Applicant: The Trustees of the University of Pennsylvania
    Inventors: Douglas H. Smith, Shu Yang, D. Kacy Cullen
  • Patent number: 7045287
    Abstract: An improved method is provided for conducting chemical or biochemical reactions on a substrate surface in which the reactions take place in an enclosed chamber between components of a fluid and molecular moieties present on an interior surface of the chamber, wherein the improvement involves mixing the fluid during the reactions and maximizing contact between the fluid's components and the entirety of the reactive interior surface by (a) applying centrifugal force to the chamber and simultaneously (b) rotating the chamber about an axis thereof. The improved method is particularly advantageous in the context of a hybridization assay in which molecular components within a sample fluid hybridize to surface-bound molecular probes (e.g., as may be present in a spatially defined and physically addressable array) within a hybridization chamber, and wherein process and device parameters (e.g., sample volume, chamber volume, temperature, number of parts and materials, and the like) are critical.
    Type: Grant
    Filed: February 21, 2001
    Date of Patent: May 16, 2006
    Assignee: Agilent Technologies, Inc.
    Inventors: Douglas H. Smith, Gary B. Gordon
  • Publication number: 20040165801
    Abstract: A hub (2) includes a spindle (14) which projects through a housing (4) and rotates relative to the housing (4) on a bearing (6) that is located between the spindle (14) and the housing (4). The bearing (6) has two sets of raceways (28,40) that are oblique to the axis x, and in addition rolling elements (36) arranged in two rows between the sets of raceways (28,40). The inner raceways (28) that fit around the spindle (14) and have back faces (32), with the back face (32) for one of the races (26) being against a shoulder (18) from which the spindle (14) projects. Initially, the end of the spindle (14) projects straight beyond the back face (32) of the outer race—indeed, so that the races (26) can be installed over the spindle (14).
    Type: Application
    Filed: February 23, 2004
    Publication date: August 26, 2004
    Inventors: Alan Charles Webb, Peter Holland, Peter Standring, Douglas H. Smith, Larry L. Bahney
  • Patent number: 6702474
    Abstract: A hub (2) includes a spindle (14) which projects through a housing (4) and rotates relative to the housing (4) on a bearing (6) that is located between the spindle (14) and the housing (4). The bearing (6) has two sets of raceways (28,40) that are oblique to the axis x, and in addition rolling elements (36) arranged in two rows between the sets of raceways (28,40). The inner raceways (28) that fit around the spindle (14) and have back faces (32), with the back face (32) for one of the races (26) being against a shoulder (18) from which the spindle (14) projects. Initially, the end of the spindle (14) projects straight beyond the back face (32) of the outer race—indeed, so that the races (26) can be installed over the spindle (14).
    Type: Grant
    Filed: July 11, 2002
    Date of Patent: March 9, 2004
    Assignee: The Timken Company
    Inventors: Alan Charles Webb, Peter Holland, Peter Standring, Douglas H. Smith, Larry L. Bahney
  • Patent number: 6688773
    Abstract: A hub (2) includes a spindle (14) which projects through a housing (4) and rotates relative to the housing (4) on a bearing (6) that is located between the spindle (14) and the housing (4). The bearing (6) has two sets of raceways (28,40) that are oblique to the axis x, and in addition rolling elements (36) arranged in two rows between the sets of raceways (28,40). The inner raceways (28) that fit around the spindle (14) and have back faces (32), with the back face (32) for one of the races (26) being against a shoulder (18) from which the spindle (14) projects. Initially, the end of the spindle (14) projects straight beyond the back face (32) of the outer race—indeed, so that the races (26) can be installed over the spindle (14).
    Type: Grant
    Filed: July 11, 2002
    Date of Patent: February 10, 2004
    Assignee: The Timken Company
    Inventors: Alan Charles Webb, Peter Holland, Peter Standring, Douglas H. Smith, Larry L. Bahney
  • Patent number: 6640438
    Abstract: A hub (2) includes a spindle (14) which projects through a housing (4) and rotates relative to the housing (4) on a bearing (6) that is located between the spindle (14) and the housing (4). The bearing (6) has two sets of raceways (28,40) that are oblique to the axis x, and in addition rolling elements (36) arranged in two rows between the sets of raceways (28,40). The inner raceways (28) that fit around the spindle (14) and have back faces (32), with the back face (32) for one of the races (26) being against a shoulder (18) from which the spindle (14) projects. Initially, the end of the spindle (14) projects straight beyond the back face (32) of the outer race—indeed, so that the races (26) can be installed over the spindle (14).
    Type: Grant
    Filed: May 11, 2001
    Date of Patent: November 4, 2003
    Assignee: The Timken Company
    Inventors: Alan Charles Webb, Peter Holland, Peter Standring, Douglas H. Smith, Larry L. Bahney
  • Publication number: 20030167233
    Abstract: A method of sharing manufacturing data with a consumer of a product is disclosed. A unique identifying indicia, such as a serial number or bar code is associated with each manufactured product. That identifying indicia is detected by the consumer of the product, through communication with the manufacturer of the product, preferably via the Internet. The manufacturer maintains a record of both the unique identifying indicia and physical properties of the specific product corresponding to the unique identifying indicia. Upon receiving a request from the consumer of the product, the manufacturer communicates the desired physical properties of the specific product associated with the unique identifying indicia to the consumer. It is therefore possible for the consumer to avoid a step of precision physical measurement of the product, since the actual physical properties have been measured by the manufacturer and recorded previously.
    Type: Application
    Filed: March 2, 2001
    Publication date: September 4, 2003
    Applicant: The Timken Company
    Inventor: Douglas H. Smith
  • Patent number: 6501382
    Abstract: A product with an automatic identification and data capture (AIDC) device associated with a physical measurement, authentication code or operating condition of the product is disclosed. A bearing with an embedded transponder is illustratively described. The transponder contains data specific to the manufactured bearing, such as physical measurements or identification numbers.
    Type: Grant
    Filed: June 11, 2001
    Date of Patent: December 31, 2002
    Assignee: Timken Company
    Inventors: Kevin E. Rehfus, Douglas H. Smith
  • Publication number: 20020186134
    Abstract: A product with an automatic identification and data capture (AIDC) device associated with a physical measurement, authentication code or operating condition of the product is disclosed. A bearing with an embedded transponder is illustratively described. The transponder contains data specific to the manufactured bearing, such as physical measurements or identification numbers.
    Type: Application
    Filed: June 11, 2001
    Publication date: December 12, 2002
    Applicant: The Timken Company
    Inventors: Kevin E. Rehfus, Douglas H. Smith
  • Publication number: 20020174544
    Abstract: A hub (2) includes a spindle (14) which projects through a housing (4) and rotates relative to the housing (4) on a bearing (6) that is located between the spindle (14) and the housing (4). The bearing (6) has two sets of raceways (28, 40) that are oblique to the axis x, and in addition rolling elements (36) arranged in two rows between the sets of raceways (28, 40). The inner raceways (28) that fit around the spindle (14) and have back faces (32), with the back face (32) for one of the races (26) being against a shoulder (18) from which the spindle (14) projects. Initially, the end of the spindle (14) projects straight beyond the back face (32) of the outer race—indeed, so that the races (26) can be installed over the spindle (14).
    Type: Application
    Filed: July 11, 2002
    Publication date: November 28, 2002
    Inventors: Alan Charles Webb, Peter Holland, Peter Standring, Douglas H. Smith, Larry L. Bahney
  • Publication number: 20020172439
    Abstract: A hub (2) includes a spindle (14) which projects through a housing (4) and rotates relative to the housing (4) on a bearing (6) that is located between the spindle (14) and the housing (4). The bearing (6) has two sets of raceways (28,40) that are oblique to the axis x, and in addition rolling elements (36) arranged in two rows between the sets of raceways (28,40). The inner raceways (28) that fit around the spindle (14) and have back faces (32), with the back face (32) for one of the races (26) being against a shoulder (18) from which the spindle (14) projects. Initially, the end of the spindle (14) projects straight beyond the back face (32) of the outer race—indeed, so that the races (26) can be installed over the spindle (14).
    Type: Application
    Filed: July 11, 2002
    Publication date: November 21, 2002
    Inventors: Alan Charles Webb, Peter Holland, Peter Standring, Douglas H. Smith, Larry L. Bahney
  • Patent number: 6457869
    Abstract: A wheel mounting includes an axle provided with a spindle, a hub located around the spindle, and an antifriction bearing located between the spindle and the hub for enabling the hub to rotate on the spindle with minimal friction. The axle also has a cylindrical ring seat located beyond its spindle and a shoulder located between the spindle and the ring seat. The ring seat has a stop located along it. The bearing has a cone located around the spindle, with its back face being against the shoulder, a cup located in the hub, and tapered rollers located between tapered raceways on the cone and cup. Beyond the large end of its raceway the cup is fitted with an excitor ring having a radial wall at the inboard end of the bearing. The ring seat carries a mounting ring having an axial wall provided with a formation that bears against the stop on the seat and an end edge that is against the back face of the inboard cone.
    Type: Grant
    Filed: September 18, 2000
    Date of Patent: October 1, 2002
    Assignee: The Timken Company
    Inventors: Douglas H. Smith, Lloyd William Sparrow, Geoffrey William Branfield
  • Patent number: 6443622
    Abstract: A hub (2) includes a spindle (14) which projects through a housing (4) and rotates relative to the housing (4) on a bearing (6) that is located between the spindle (14) and the housing (4). The bearing (6) has two sets of raceways (28, 40) that are oblique to the axis x, and in addition rolling elements (36) arranged in two rows between the sets of raceways (28, 40). The inner raceways (28) that fit around the spindle (14) and have back faces (32), with the back face (32) for one of the races (26) being against a shoulder (18) from which the spindle (14) projects. Initially, the end of the spindle (14) projects straight beyond the back face (32) of the outer race—indeed, so that the races (26) can be installed over the spindle (14).
    Type: Grant
    Filed: December 23, 1999
    Date of Patent: September 3, 2002
    Assignee: The Timken Company
    Inventors: Alan Charles Webb, Peter Holland, Peter Standring, Douglas H. Smith, Larry L. Bahney
  • Patent number: 6365153
    Abstract: Mechanically elongated neuronal cells and methods of mechanically producing elongated cells are provided. Also provided are methods for transplanting elongated neuronal cells into an animal for treatment of spinal cord injuries and other nerve injuries.
    Type: Grant
    Filed: March 6, 2001
    Date of Patent: April 2, 2002
    Inventor: Douglas H. Smith