Abstract: Disclosed herein are methods, compositions, kits, and agents useful for inducing ? cell maturation, and isolated populations of SC-? cells for use in various applications, such as cell therapy.

Abstract: The present invention relates to novel cGAS inhibitor compounds, having a formula of: to pharmaceutical compositions comprising the compounds, and to methods of using the compounds and compositions to treat certain pathological conditions such as immune-mediated diseases.

Abstract: According to examples, an image capture device may include a lens array including lenses supported by a lens support structure, in which the lenses are arranged to capture light rays from multiple view-points. The image capture device may also include a sensor to capture light and convert the captured light into data that is used to form an image and a plurality of apertures positioned between the lenses and the sensor, in which the apertures are positioned with respect to the lenses and the sensor to allow rays of light that would have reached a certain reference location spaced from the sensor to pass through the plurality of apertures. An optimization algorithm may be applied to the collected sensor data to reproduce an image of a scene at a perspective that is intended to match a virtual eye position that is offset from the location of the sensor.

Abstract: Systems, devices, and methods are disclosed for wireless communication of analyte data. In embodiments, a method of using a diabetes management partner interface to configure an analyte sensor system for wireless communication with a plurality of partner devices is provided. The method includes the analyte sensor system receiving authorization to provide one of the partner devices with access to a set of configuration parameters via the diabetes management partner interface. The set of configuration parameters is stored in a memory of the analyte sensor system. The method also includes, responsive to input received from the one partner device via the diabetes management partner interface, the analyte sensor system setting or causing a modification to the set of configuration parameters, according to a system requirement of the one partner device.

Abstract: A drive system for a rotorcraft includes first and second gearbox assemblies and a lubrication assembly. The lubrication assembly includes first and second lubrication systems and a valve connected between the first and second lubrication systems such that when the valve is in a first position, a test mode of operation of the lubrication assembly is enabled and when the valve is in a second position, a normal mode of operation of the lubrication assembly is enabled. The lubrication assembly also includes a valve control unit operable to instruct the valve to selectively move between the first position and the second position.

Abstract: A water drainage assembly for an aftertreatment system includes: a tube having an inlet structured to be coupled to an outlet conduit of an aftertreatment system; a drain port extending through the tube; a first baffle disposed in the tube, a first baffle first end attached to an inner surface of the tube at a first location, wherein at least a portion of the first baffle is inclined downwards with respect to gravity; and a second baffle disposed in the tube below the first baffle, a second baffle first end being coupled to the inner surface of the tube at a second location that is opposite to and below the first location, wherein at least a portion of the second baffle is inclined upwards with respect to gravity.

Abstract: A method and a system of deploying an ignition interlock device (IID). The method comprises receiving a time series of breath alcohol content (BrAC) measurements that are unitarily sourced from a pre-identified user, each BrAC measurement of the time series including an alveolar breath component and an interferent breath component; estimating a dissipation rate of alcohol attributable to the pre-identified user in accordance with the time series of BrAC measurements; determining, responsive to estimating the dissipation rate of alcohol, at least a subset of the BrAC measurements as being based on the alveolar breath component but not the interferent breath component; and performing one of triggering and not triggering the IID into a lockout state based on the at least a subset of the BrAC measurements.

Abstract: A volumetric display may include a two-dimensional display; a varifocal optical system configured to receive image light from the two-dimensional display and focus the image light; and at least one processor configured to: control the two-dimensional display to cause a plurality of sub-frames associated with an image frame to be displayed by the display, wherein each sub-frame of the plurality of sub-frames includes a corresponding portion of image data associated with the image frame; and control the varifocal optical system to a corresponding focal state for each respective sub-frame.

Abstract: Methods and systems for characterizing a user or a session associated with a user interface and customizing the user interface responsive to the characterization such that a sales transaction is facilitated. The methods and systems are applicable in the vehicle sales, leasing, subscription, and rental contexts, as well as in other contexts.

Abstract: Methods and systems for optimizing a user experience such that customers/users who are online looking to purchase or lease/subscribe/rent vehicles are presented UI/UX user flows defaulting to or otherwise favoring a vehicle model/version (and trim and color and add-ons) that are as optimal as possible for both the customer/user and for the vehicle manufacturer. These concepts may be extended beyond the automotive context as well.

Abstract: The invention relates to an adjustable mechanical valve assembly used to control fluid flow in a pipe system that compresses air bubbles in the fluid to allow a more dense volume of fluid to exit the control valve. The valve assembly comprises a housing, a valve member, a spring member, and a retaining member. The spring member is configured to limit radial movement while allowing axial movement, thereby eliminating the need for a separate element (such as a rod) to limit radial movement.

Abstract: A head-mounted display device includes a first set of one or more lenses and a first display configured to provide visual data through the first set of one or more lenses. The head-mounted display device further includes a first stepper motor mechanically coupled to the first display, and the first stepper motor is configured to move the first display along a first axis by rotating a rotatable component of the first stepper motor. The head-mounted display device further includes a first electronic controller configured to (i) determine a first position of the first display, (ii) receive information identifying a second position of the first display, and (iii) generate one or more electrical signals that cause the first stepper motor to move the first display from the first position to the second position along the first axis.

Abstract: A drive system for a rotorcraft includes first and second gearbox assemblies and a lubrication assembly. The lubrication assembly includes first and second lubrication systems and a valve connected between the first and second lubrication systems such that when the valve is in a first position, a test mode of operation of the lubrication assembly is enabled and when the valve is in a second position, a normal mode of operation of the lubrication assembly is enabled. The lubrication assembly also includes a valve control unit operable to instruct the valve to selectively move between the first position and the second position.

Abstract: A sodium electrochemical cell that supports a current density at the negative electrode of at least 500 ?A/cm2, the electrochemical cell comprising (i) a negative electrode and (ii) a sodium-ion ionic liquid electrolyte having a sodium-ion concentration that is no less than 75% of its saturation limit in the electrolyte, wherein the negative electrode has a solid-electrolyte interphase (SEI) layer formed as a result of the electrochemical cell having undergone a polarisation cycle.

Abstract: A head-mounted display device for providing images to a wearer includes a focus-supporting light projector and a beam steerer. The focus-supporting light projector is configured to project light for rendering images based at least on virtual reality contents and/or augmented reality contents. The light projected from the focus-supporting light projector corresponds to an image plane that is selected based at least in part on a position of a pupil of an eye of the wearer. The beam steerer is configured to change a path of the light projected from the focus-supporting light projector based on the position of the pupil of the eye of the wearer.

Abstract: A transversal radio frequency filter circuit having a low noise amplifier connected along an input signal path, a first power divider connected between the low noise amplifier and four single taps, and an output path connected to the outputs of each of the four single taps. Each of the four single taps having a coefficient control mechanism, a polarity selection mechanism, and a time delay element. The coefficient control mechanism can include a wideband digital step attenuator configured to support high control range of the coefficient. Additionally, the circuit can include a second power divider connected between the outputs of each of the four single taps and the output path. The circuit can further include a field-programmable gate array configured to control coefficient control mechanisms, the polarity selection mechanisms, and the time delay elements (when they are variable time delay elements).

Abstract: A fluid pump system for an aircraft has a rotatable component having first and second fluid ports, each port in fluid communication with a selected interior portion of the component, the portions being spaced from each other. A valve controls allows a first flow rate through the first fluid port and allows a second flow rate through the second fluid port when the component is in a first angular orientation. The valve allows a third flow rate through the first fluid port and allows a fourth flow rate through the second fluid port when the component is in a second angular orientation.

Abstract: A device includes a first-type liquid crystal (LC) lens configured to provide a first optical power that is variable in a first step resolution. The device also includes a second-type LC lens coupled with the first-type LC lens, and configured to provide a second optical power that is variable in a second step resolution. The first step resolution is smaller than the second step resolution. A total optical power of the device is a sum of the first optical power and the second optical power, and is variable in the first step resolution.

Abstract: A fluid pump system for an aircraft has a rotatable component having first and second fluid ports, each port in fluid communication with a selected interior portion of the component, the portions being spaced from each other. A valve controls allows a first flow rate through the first fluid port and allows a second flow rate through the second fluid port when the component is in a first angular orientation. The valve allows a third flow rate through the first fluid port and allows a fourth flow rate through the second fluid port when the component is in a second angular orientation.