Abstract: Compounds of the formula and pharmaceuticaly acceptable salts thereof, wherein Q1 and R1 are defined herein, inhibit the IGF-1R enzyme and are useful for the treatment and/or prevention of various diseases and conditions that respond to treatment by inhibition of tyrosine kinases.

Abstract: In accordance with embodiments within, a secure independent electronic document apparatus, it's system, method, and manufacture is taught. With an authenticable and tamper detectable electronic container supporting platform vendor and authentication independence, character text data sections supporting digital signatures, data automation and nested embedding, as well as graphical image data, or other free format data sections supporting many data processing operations, imaging representation comprised within a container using a secure and independent system, the secure independent electronic document presents a solution for digital electronic information distribution, commerce, trade and exchange.

Abstract: A system for performing a less invasive surgical procedure and, in particular, devices and methods for spinal fixation. The system comprises dilation tool(s), at least one working/insertion cannula, a plurality of screws, at least one fixation rod for connecting the screws, and a rod inserter. The dilation tool(s) may be used to dilate an incision made in a patient to form an opening. Thereafter, a drill may be used to form holes in the vertebrae. An insertion cannula may be attached to a screw and inserted into the opening. The screws may be polyaxial screws and may be inserted into the vertebrae using a screwdriver. An operator may then move the insertion cannula to manipulate a head portions of the screws such that the head portions may be aligned to receive a fixation rod. A rod inserter may be used to insert a fixation rod into the head portions. After the fixation rod is in place, it may be locked to the screws, thereby fixing the system in place on the spine.

Abstract: A feed injector for providing feed to a gasifier of an integrated gasification combined cycle system includes: a base leading to a body and terminating in a tip, the tip including an exitway for injecting feed into the gasifier; the tip including a mating of an inner shell disposed within a core insert, with an outer shell in which the core insert is disposed; a plurality of spacers disposed between the core insert and inner shell thus providing an inner annular space, and another plurality of spacers disposed between the core insert and outer shell thus providing an outer annular space; the inner annular space and the outer annular space being in fluid communication at the tip and providing for a flow of coolant from the base to the tip and back to the base. A method of fabrication and an integrated gasification combined cycle power plant are also disclosed.

Abstract: A computer implemented method, data processing system, and computer usable program code are provided for associating historical events with a user. A historical event is identified for association with the user. A determination is made as to whether the historical event has been certified by a trusted authority in response to identifying the historical event for association with the user. A historical object is created for the historical event if the historical event has been certified by the trusted authority and associated with the user.

Abstract: Log chirp testing where a log chirp may be provided to a device under test and a first time domain response from the device under test may be received. The first time domain response may be in the time domain. The first time domain response may be converted to the angular domain to create an angular domain response. Converting to the angular domain response may include resampling the time domain response from the time domain to the angular domain. The angular domain response may be filtered and/or analyzed. The angular domain response may be converted to a second time domain response. Similar to above, the conversion may include resampling the angular domain response from the angular domain to the time domain. The first time domain response and the second time domain response may be analyzed. Testing results of the device under test may be generated and stored based on said analyzing.

Abstract: A sprinkler is disclosed for improved flow characteristics. The sprinkler has a sprinkler head rotatably supported for distributing water and defining a flow channel for directing water flow therethrough with reduced head loss. The flow channel has a smoothly tapered portion for receiving water and channeling the water towards an outlet in communication with a first nozzle for distributing the water. The flow channel with reduced head loss produces a greater throw distance at a lower trajectory with a lower flow rate and pressure. The flow channel may be formed within a flow channel member positioned within the sprinkler head. The flow channel member may cooperate with the sprinkler head to define a cavity allowing water to pass through the cavity from the flow channel for emission from a plurality of other nozzles.

Abstract: A system and architecture for managing lighting through a seamless low-voltage bus network is disclosed. The system comprises a plurality of control units that serve as nodes for integrating devices, such as light fixtures, control switches and sensors into the bus. Each of the control units preferably includes a printed circuit board and node interconnects for assembling the low-voltage bus and for integrating the devices. Alternatively, the system comprises a central hub with a master printed circuit control board and a plurality of interconnects for assembling the bus and for integrating the devices.

Abstract: A system for performing a less invasive surgical procedure and, in particular, devices and methods for spinal fixation. The system comprises dilation tool(s), at least one working/insertion cannula, a plurality of screws, at least one fixation rod for connecting the screws, and a rod inserter. The dilation tool(s) may be used to dilate an incision made in a patient to form an opening. An insertion cannula may be attached to a screw and inserted into the opening. The screws may be polyaxial screws and may be inserted into the vertebrae using a screwdriver. An operator may then move the insertion cannula to manipulate a head portion of the screws such that the head portions may be aligned to receive a fixation rod. A rod inserter may be used to insert a fixation rod into the head portions.

Abstract: An optical broadband micro-spectrometer containing an input optical assembly, a group of slab waveguide spatial heterodyne spectrometer (SHS) integrated circuits (ICs), a detection module and a processor for multi-line detection. The input optical assembly applies an input light signal uniformly with respect to brightness and frequency to the apertures of the waveguides and may project a pupil image onto the SHS input face and may be a scanner. Each slab waveguide spatial heterodyne spectrometer (SHS) integrated circuit (IC) contains at least one slab waveguide SHS IC. The detection module bonds directly to the slab waveguide output apertures. Each slab waveguide SHS IC may contain one or more slab waveguide SHS.

Abstract: A primary node and a secondary node each run the same J2EE compliant middleware stack comprising layers including a load balancer, a web server, a web application server, a message control server, a monitoring server, and a database control server. In the primary node, all layers are active. In the secondary node, part of the layers are active and part of the layers are in standby. A data replication partition shared between the primary node and the secondary node includes persistent resource data accessible to a selection of the layers of the primary node. A heartbeat controller monitors each node, including the middleware stack, and upon detection of a failure, controls transfer of the services provided by the primary node to the secondary node by transferring virtual IP addresses from the primary node to the secondary node, remounting the data replication partition for access by the secondary node, and activating the standby layers which require access to the data in the data replication partition.

Abstract: A power distribution module includes a housing having a component chamber configured to house an electrical component therein. The housing includes at least a portion thereof defining a shield interface. A header assembly is coupled to the housing. The header assembly includes a header body including an inner body portion and an outer body portion, and the header assembly further includes a header shield positioned between the inner and outer body portions. The header shield engages the shield interface of the housing when the header assembly is coupled to the housing.

Abstract: A system for routing different data types along different client-to-network connection paths. A connection utility, at the client, monitors a data type being transmitted. When a first data type is being transmitted, the connection utility selects a most optimal (or efficient) connection route for that data type. The connection utility then assigns a next connection route for a second data type with different characteristics and/or routing requirements than the first data type. Differences in routing path that are factored into the criteria for selection include: wired versus wireless, level of security, transfer protocol, connection cost, speed, etc.

Abstract: Embodiments disclosed herein provide a system and method for associating data records in multiple languages within a single hub. As a record comes in from an information source coupled to the hub, it is associated with a particular language at a core layer. The hub maps each language one-to-one to a member type. For each data record of a particular member type, unique derivation code is utilized to perform standardization and bucketing at a derived layer. A weight may be used to balance the richness of languages so that data records in different languages can have the same statistical meaning. Since attributes are standardized with respect to a language of a data record, appropriate languages or script can be passed along with the data record. The hub can then match the data record to the optimum algorithm(s) for entity processing at an entity layer.

Abstract: A banana shaped intevertebral fusion cage having a domed profile, an internal planar wall defining first and second graft chambers, asymmetrically disposed leading and trailing insertion, and an anterior wall recess.

Abstract: An apparatus for cooling air for an intake to a gas turbine, is provided and includes a pressurized water piping and nozzle apparatus for producing a water spray in an airflow to the intake; and evaporative media for receiving the spray and causing a pressurizing of the air in the airflow.