Abstract: A catheter may include electrodes for transvascular nerve stimulation. The electrodes may be positioned within lumens of the catheter and aligned with apertures in the outer wall of the catheter. The electrodes may produce focused electrical fields for stimulation of one or more nerves. In one embodiment, the catheter may include a set of proximal electrodes and a set of distal electrodes, and the proximal electrodes may stimulate a patient's left phrenic nerve and the distal electrodes may stimulate a patient's right phrenic nerve.

Abstract: This disclosure describes, among other embodiments, systems and related methods for selecting electrode combinations to be used during nerve pacing procedures. A first set of electrode combinations of a nerve pacing system, such as a phrenic nerve pacing system for diaphragm activation, may be mapped (or tested) to determine the location of the electrode combinations relative to a target nerve. Once the general location of the target nerve is known, a more localized second set of electrode combinations may be tested to determine the most suitable electrode combinations for nerve stimulation. At various stages of the mapping process, electrode combinations that are non-optimal may be discarded as candidates for use in a nerve pacing procedure. The systems and methods described herein may allow for the selection of electrode combinations that are most suitable for stimulation of the left and right phrenic nerves during diaphragm pacing.

Abstract: A catheter may include electrodes for transvascular nerve stimulation. The electrodes may be positioned within lumens of the catheter and aligned with apertures in the outer wall of the catheter. The electrodes may produce focused electrical fields for stimulation of one or more nerves. In one embodiment, the catheter may include a set of proximal electrodes and a set of distal electrodes, and the proximal electrodes may stimulate a patient's left phrenic nerve and the distal electrodes may stimulate a patient's right phrenic nerve.

Abstract: A catheter may include electrodes for transvascular nerve stimulation. The electrodes may be positioned within lumens of the catheter and aligned with apertures in the outer wall of the catheter. The electrodes may produce focused electrical fields for stimulation of one or more nerves. In one embodiment, the catheter may include a set of proximal electrodes and a set of distal electrodes, and the proximal electrodes may stimulate a patient's left phrenic nerve and the distal electrodes may stimulate a patient's right phrenic nerve.

Abstract: A catheter may include electrodes for transvascular nerve stimulation. The electrodes may be positioned within lumens of the catheter and aligned with apertures in the outer wall of the catheter. The electrodes may produce focused electrical fields for stimulation of one or more nerves. In one embodiment, the catheter may include a set of proximal electrodes and a set of distal electrodes, and the proximal electrodes may stimulate a patient's left phrenic nerve and the distal electrodes may stimulate a patient's right phrenic nerve.

Abstract: An apparatus for engaging and moving a ram block. In some embodiments, the apparatus, or ram block changer, includes a support bracket coupled to a blowout preventer and an articulated arm releasably coupled to the ram block. The ram block changer may further include a pivot coupling assembly having a first axis of rotation. The pivot coupling assembly extends through the support bracket and the articulated arm, wherein the articulated arm is rotatable about the first axis of rotation relative to the support bracket. The articulated arm may include a first member receiving the pivot coupling assembly therethrough, a second member coupled to the ram block, and a second pivot coupling assembly having a second axis of rotation spaced apart from the first axis of rotation and extending through the first and second members. The second member is rotatable about the second axis of rotation relative to the first member.

Abstract: A compressive imaging system includes an illumination system arranged to illuminate an object of interest with illumination light, and a detection system configured to detect at least a portion of the illumination light after being at least one of reflected from, scattered from, or transmitted through the object of interest or to detect fluorescent light from the object of interest and to provide an imaging signal. The compressive imaging system further includes an image processing system configured to communicate with the detection system to receive the imaging signal. The illumination light from the illumination system comprises a plurality of light pulses such that each light pulse has a preselected spectrum that is distinguishable from spectra of all other pulses. The image processing system is configured to form an image of the object of interest using information concerning the preselected spectra of the plurality of light pulses.

Abstract: This disclosure describes, among other embodiments, systems and related methods for selecting electrode combinations to be used during nerve pacing procedures. A first set of electrode combinations of a nerve pacing system, such as a phrenic nerve pacing system for diaphragm activation, may be mapped (or tested) to determine the location of the electrode combinations relative to a target nerve. Once the general location of the target nerve is known, a more localized second set of electrode combinations may be tested to determine the most suitable electrode combinations for nerve stimulation. At various stages of the mapping process, electrode combinations that are non-optimal may be discarded as candidates for use in a nerve pacing procedure. The systems and methods described herein may allow for the selection of electrode combinations that are most suitable for stimulation of the left and right phrenic nerves during diaphragm pacing.

Abstract: The humidifier has an upper tank and a lower reservoir. A liquid level switch in the lower reservoir works in conjunction with a valve in a water passage between the upper tank and the lower reservoir in order to provide an automated flow of water to the lower reservoir during operation of the humidifier. The upper tank is unsealed, such that air in the upper tank may equalize with an ambient air pressure. The humidifier can be top-filled allowing that the upper tank to be permanently affixed to the base of the humidifier.

Abstract: This disclosure describes, among other embodiments, systems and related methods for selecting electrode combinations to be used during nerve pacing procedures. A first set of electrode combinations of a nerve pacing system, such as a phrenic nerve pacing system for diaphragm activation, may be mapped (or tested) to determine the location of the electrode combinations relative to a target nerve. Once the general location of the target nerve is known, a more localized second set of electrode combinations may be tested to determine the most suitable electrode combinations for nerve stimulation. At various stages of the mapping process, electrode combinations that are non-optimal may be discarded as candidates for use in a nerve pacing procedure. The systems and methods described herein may allow for the selection of electrode combinations that are most suitable for stimulation of the left and right phrenic nerves during diaphragm pacing.

Abstract: A catheter may include electrodes for transvascular nerve stimulation. The electrodes may be positioned within lumens of the catheter and aligned with apertures in the outer wall of the catheter. The electrodes may produce focused electrical fields for stimulation of one or more nerves. In one embodiment, the catheter may include a set of proximal electrodes and a set of distal electrodes, and the proximal electrodes may stimulate a patient's left phrenic nerve and the distal electrodes may stimulate a patient's right phrenic nerve.

Abstract: A catheter may include electrodes for transvascular nerve stimulation. The electrodes may be positioned within lumens of the catheter and aligned with apertures in the outer wall of the catheter. The electrodes may produce focused electrical fields for stimulation of one or more nerves. In one embodiment, the catheter may include a set of proximal electrodes and a set of distal electrodes, and the proximal electrodes may stimulate a patient's left phrenic nerve and the distal electrodes may stimulate a patient's right phrenic nerve.

Abstract: A central body, preferably circular or rotund, has a plurality of elongated arms radiating out from it. Each arm includes a rigid blade end that defines a profile that operationally fits over a fingernail at an angle of incidence for masking an area of the fingernail during painting, or for scoring semi-hardened paint and scraping off excess paint. Angle of incidence is preferably acute, obtuse or right. Each blade end preferably operationally fits over a uniquely corresponding relatively small range of fingernail sizes. The end blades are disposed in order in a direction around the body, the order being progressively larger range sizes. A mark on each end blade is used for aligning the end blade with a longitudinal axis of a fingernail.

Abstract: This disclosure describes, among other embodiments, systems and related methods for selecting electrode combinations to be used during nerve pacing procedures. A first set of electrode combinations of a nerve pacing system, such as a phrenic nerve pacing system for diaphragm activation, may be mapped (or tested) to determine the location of the electrode combinations relative to a target nerve. Once the general location of the target nerve is known, a more localized second set of electrode combinations may be tested to determine the most suitable electrode combinations for nerve stimulation. At various stages of the mapping process, electrode combinations that are non-optimal may be discarded as candidates for use in a nerve pacing procedure. The systems and methods described herein may allow for the selection of electrode combinations that are most suitable for stimulation of the left and right phrenic nerves during diaphragm pacing.

Abstract: A catheter may include electrodes for transvascular nerve stimulation. The electrodes may be positioned within lumens of the catheter and aligned with apertures in the outer wall of the catheter. The electrodes may produce focused electrical fields for stimulation of one or more nerves. In one embodiment, the catheter may include a set of proximal electrodes and a set of distal electrodes, and the proximal electrodes may stimulate a patient's left phrenic nerve and the distal electrodes may stimulate a patient's right phrenic nerve.

Abstract: The invention, in one aspect, relates to an intravascular electrode system. The system comprises one or more electrodes supported on an elongated resiliently flexible support member, and the support member may be used to introduce the electrodes into a blood vessel. As the support member is introduced into the blood vessel the support member bends to follow the path of the blood vessel.

Abstract: An apparatus for engaging and moving a ram block. In some embodiments, the apparatus, or ram block changer, includes a support bracket coupled to a blowout preventer and an articulated arm releasably coupled to the ram block. The ram block changer may further include a pivot coupling assembly having a first axis of rotation. The pivot coupling assembly extends through the support bracket and the articulated arm, wherein the articulated arm is rotatable about the first axis of rotation relative to the support bracket. The articulated arm may include a first member receiving the pivot coupling assembly therethrough, a second member coupled to the ram block, and a second pivot coupling assembly having a second axis of rotation spaced apart from the first axis of rotation and extending through the first and second members. The second member is rotatable about the second axis of rotation relative to the first member.

Abstract: An apparatus for engaging and moving a ram block. In some embodiments, the apparatus, or ram block changer, includes a support bracket coupled to a blowout preventer and an articulated arm releasably coupled to the ram block. The ram block changer may further include a pivot coupling assembly having a first axis of rotation. The pivot coupling assembly extends through the support bracket and the articulated arm, wherein the articulated arm is rotatable about the first axis of rotation relative to the support bracket. The articulated arm may include a first member receiving the pivot coupling assembly therethrough, a second member coupled to the ram block, and a second pivot coupling assembly having a second axis of rotation spaced apart from the first axis of rotation and extending through the first and second members. The second member is rotatable about the second axis of rotation relative to the first member.

Abstract: Disclosed herein are a product containing an extract from Zanthoxylum avicennae (Lam.) DC. and a process for preparing the same. Also disclosed herein are a pharmaceutical composition including the aforesaid product containing the extract from Zanthoxylum avicennae (Lam.) DC., a method of treating a cancer in a subject via the aforementioned pharmaceutical composition, and a method of inhibiting tumor/cancer cells by virtue of the aforesaid product containing the extract from Zanthoxylum avicennae (Lam.) DC.

Abstract: Methods and apparatus for applying a single virtual private network (VPN) address to tunnels or connections associated with different access interfaces are disclosed. In one embodiment, a method includes establishing a first tunnel between a node and a VPN server. The first tunnel has a first address. The method also includes assigning a VPN address to the first tunnel, as well as establishing a second tunnel between the node and the VPN server. The second tunnel has a second address. The VPN address is assigned to the second tunnel, and VPN address is accessed by both the first address and the second address.