Abstract: A bone screw comprising a shaft having a wall, the wall including a minor diameter and at least one thread having an external thread form. The thread form including a first portion comprising a crest of the thread form and a second portion extends between a minor diameter of the thread form and the first portion. The first portion having a solid configuration relative to the second portion. In some embodiments, systems, spinal constructs, surgical instruments and methods are disclosed.

Abstract: Embodiments include systems and methods of in-line mixing of hydrocarbon liquids from a plurality of tanks into a single pipeline. According to an embodiment, a method of admixing hydrocarbon liquids from a plurality of tanks into a single pipeline to provide in-line mixing thereof includes determining a ratio of a second fluid flow to a first fluid flow based on signals received from a tank flow meter in fluid communication with the second fluid flow and a booster flow meter in fluid communication with a blended fluid flow. The blended fluid flow includes a blended flow of the first fluid flow and the second fluid flow. The method further includes comparing the determined ratio to a pre-selected set point ratio thereby to determine a modified flow of the second fluid flow to drive the ratio toward the pre-selected set point ratio.

Abstract: A method of processing raw poultry parts to produce a product continuing to qualify as a raw food product, including killing pathogens by increasing the core temperature to a regulatory-required temperature for a regulatory-required duration using mist heated to a temperature not denaturing or deforming the product skin in a manner resulting in a product continuing to have the appearance of a raw delicacy product. Included is an apparatus implementing said method, including a diagonally ascending heating track or chamber substantially filled with a screw auger conveying the poultry parts through the heating process, and a diagonally descending exit chute whereby the heat-processed parts exit the apparatus for final processing for packaging. Also included is a sub-system for recovering and re-using the misting liquids and other liquids exiting the parts, including filtration en route to a reservoir supplying the media for heating for misting the poultry parts.

Abstract: Disclosed herein is a garment configured to deliver electrical current from a remote power supply to electrically stimulate tissue of a foot of an individual. The garment can comprise a fabric and can be shaped to fit over the foot and a portion of a leg of the individual. The fabric can be configured to cause the garment body to conform to the foot when worn by the individual. The garment can further comprise a first electrode region integrated within the garment body and configured to engage a plantar region of the foot. The garment can further comprise a second electrode region integrated within the garment body and spaced from the first electrode region and configured to engage the plantar region of the foot.

Abstract: The present aspects include a magnetic detacher including a housing having a wall that defines a nest configured to receive a security tag; a gate member and an actuator configured to move the gate member between a closed position and an open position, wherein the gate member in the closed position blocks the nest, and in the open position allows access to the nest; a magnet positioned on an opposite side of the housing relative to the nest and adjacent to the nest, the magnet having a field in an area of the nest sufficient to unlock a magnetic lock of the security tag; and a processor in communication with the actuator and with a transaction system, wherein the processor is configured to control the actuator to move the gate member from the closed position to the open position based on receipt of an unlock signal from the transaction system.

Abstract: A bone screw comprises a shaft defining a longitudinal axis and a minor diameter. The shaft including a core having an angled surface relative to the axis. The angled surface extending from the minor diameter adjacent a proximal portion of the shaft to a distal portion of the shaft, and a wall disposed about the angled surface. The wall including at least one thread having an external thread form. In some embodiments, systems, spinal constructs, surgical instruments and methods are disclosed.

Abstract: Provided herein are conjugates comprising a protein and an oligosaccharide of one of Formulae I-VI. Also provided herein are pharmaceutical compositions comprising such conjugates. Further provided herein are methods of treating a lysosomal storage disorder in a mammal by administration of an oligosaccharide-glycoprotein conjugate.

Abstract: Per-and polyfluoroalkyl substances (PFAS) are destroyed by oxidation in supercritical conditions. PFAS in water can be concentrated and prepared for destruction in a pretreatment phase. Following annihilation of the PFAS in supercritical conditions to levels below 5 parts per trillion (ppt), the water effluent can be used to recover heat, returned to sub-critical conditions, and then released back into the environment.

Abstract: A system comprises at least one computer device in communication with one or more server computers. The system converts unstructured text into usable order details, and uses instant messaging to notify recipients of the order details. The notices include electronic web links that launch a web interface that generates an editable, pre-populated electronic order ticket based on the order details. Submission of the electronic order ticket launches an auction during which the recipients may respond with offers to fulfill to the electronic order ticket. If after the auction more than one response is needed to fill the electronic order ticket, the system automatically allocates how and in which order the responses will be used to fill the electronic order ticket. If the electronic order ticket is not completely filled after the auction, the electronic order ticket is submitted to one or more additional exchanges for further filling.

Abstract: Drop-in and under-deck firestop devices including a sleeve structure having an inner surface and an opposite outer surface. The firestop device includes a first smoke-seal ring positioned on the inner surface of the sleeve structure, a first intumescent ring positioned below the first smoke-seal ring on the inner surface of the sleeve structure, a second smoke-seal ring positioned on the outer surface of the sleeve structure; and a second intumescent ring positioned below the second smoke-seal ring on the outer surface of the sleeve structure. The first and second smoke-seal rings and the first and second intumescent rings are respectively adhered or otherwise secured to the inner and outer surfaces of the sleeve structure.

Abstract: In some aspects, the present disclosure provides a nanoparticle composition comprising tRNA and an aminolipid delivery compound. The aminolipid delivery compound may be a dendrimer, dendron, or dendritic lipid, a polymer such as a polyamide or polyester, or a lipid with one or more hydrophobic components. In some embodiments, these compositions may be administered to a patient to treat a genetic disease or disorder such as cystic fibrosis, Duchene muscular dystrophy, or cancer.

Abstract: Disclosed herein are methods, compositions and systems useful for genetically engineering subcellular compartments such as OMVs for synthetic biology applications. In an embodiment, genetically engineered bacteria use OMVs to secrete compounds or proteins of interest extracellularly where the compounds or proteins of interest can be isolated from the growth media.

Abstract: A method and apparatus for rotating a test specimen and simultaneously applying a torque, bending moment, and an axial load without the applied forces interfering with each other.

Abstract: A system of object detection for a trailer. In one example, the system includes a camera configured to capture images of the trailer, where the images include an object other than the trailer. The system also includes a sensor configured to capture sensor data, a display configured to display images from the perspective of the camera, and a controller on the vehicle. The controller includes an electronic processor configured to receive the image data from the camera, receive the sensor data from the sensor, determine a blind spot, analyze the sensor data for radar data associated with the object, calculate the position of the object relative to the blind spot and the trailer, determine that the object is within the blind spot using an object detection algorithm, and in response to the determining that the object is within the blind spot, generate an augmented image.

Abstract: Disclosed are methods and a pharmaceutical composition for the prevention and treatment of fibrosis by the inhibition of fibronectin matrix assembly, as well as insights into the molecular mechanism by which cell-mediated assembly of fibronectin (FN) matrix contributes to extracellular matrix (ECM) accumulation. Peptides S2, S3, S20, and variants thereof may be utilized, either alone or fused to one or more proteins. In one aspect, a construct comprising a first protein fused to a first end of a peptide and a second protein fused to a second end of the peptide may be used, where the peptide has at least 80% sequence identity to S2, S3, or S20. The peptide may then be allowed to interact with fibronectin.

Abstract: Crystalline forms of Compound I: pharmaceutically acceptable salts thereof, and solvates and hydrates thereof are disclosed. Pharmaceutical compositions comprising the same, methods of treating cystic fibrosis using the same, and methods for making the same are also disclosed.

Abstract: A shower assembly includes a stationary base and an inlet assembly configured to rotate relative to the stationary base. The inlet assembly includes a pivot rotatably coupled to the stationary base, a first arm extending radially from the pivot, and a second arm extending radially from the pivot, opposite the first arm. The shower assembly further includes a showerhead disposed on an end of the first arm and a first ball joint disposed between the showerhead and the end of the first arm. A docking member is disposed on an end of the second arm and has a second ball joint disposed between the docking member and the end of the second arm. The docking member includes a magnet disposed therein. A removable hand shower including a ferromagnetic element is configured to magnetically couple to the magnet of the docking member.

Abstract: Drivetrain assemblies for personal care devices to generate controllable power tapping motion alone or with controllable sweeping motion. The drivetrain assemblies include a drivetrain shaft at least partially contained within a body portion. The drivetrain shaft is further configured to engage a brush head member. Some drivetrain assemblies include a single actuator for generating periodic linear movement, wherein the drivetrain shaft transmits the linear movement to the brush head member via a pivoting motion and/or a translational motion. Other drivetrain assemblies include the actuator for generating periodic linear movement and a motor on the drivetrain shaft to periodically rotate the shaft about a central axis.

Abstract: A structured tissue belt assembly including a supporting layer, a non-woven web contacting layer, and one or more laser welds that attach the bottom surface of the web contacting layer to the top surface of the supporting layer. The structured tissue belt assembly allows for air flow in x, y and z directions. In exemplary embodiments, the structured tissue belt assembly has an embedment distance between the supporting layer and the web contacting layer of 0.05 mm to 0.60 mm and a peel force between the web contacting layer and the supporting layer of at least 650 gf/inch.