Patents by Inventor E Zhang

E Zhang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Metabolites of prinomastat and their synthesis
    Publication number: 20040053922
    Abstract: Metabolites of a matrix metalloproteinase inhibitor prinomastat and their synthesis. These metabolites are: (3S)-N-hydroxy4-(4-((1-oxy-pyrid-4-yl)oxy)benzenesulfonyl)-2,2-dimethyl-tetrahydro-2H-1,4-thiazine-3-carboxamide (M6); (3S)-2,2-dimethyl-1,1-dioxo-4-[4-(1-oxy-pyridin-4-yloxy)-benzenesulfonyl]-thiomorpholine-3-carboxylic acid amide (M7); (3S)-2,2-dimethyl-4-[4-(1-oxypyridin-4-yloxy)-benzenesulfonyl]-thiomorpholine-3-carboxylic acid amide (M8); (3S)-2,2-dimethyl-1,1-dioxo-4-[4-(pyridin-4-yloxy)-benzenesulfonyl]-thiomorpholine-3-carboxylic acid amide (M2); and (3S)-2,2-dimethyl-4-[4-(pyridin-4yloxy)-benzenesulfonyl)-thiomorphpline-3-carboxylic acid amide (M3).
    Type: Application
    Filed: June 10, 2003
    Publication date: March 18, 2004
    Applicant: Agouron Pharmaceuticals, Inc.
    Inventors: Michael A. Ouellette, Barbara C.M. Potts, Jayaram K. Srirangam, Anthony R. Tibbetts, Kanyin E. Zhang
  • HIV protease inhibitors
    Patent number: 6001851
    Abstract: HIV protease inhibitors, obtainable by chemical synthesis, inhibit or block the biological activity of the HIV protease enzyme, causing the replication of the HIV virus to terminate. These compounds, as well as pharmaceutical compositions that contain these compounds and optionally other anti-viral agents as active ingredients, are suitable for treating patients or hosts infected with the HIV virus, which is known to cause AIDS.
    Type: Grant
    Filed: March 12, 1998
    Date of Patent: December 14, 1999
    Assignee: Agouron Pharmaceuticals, Inc.
    Inventors: Kim F. Albizati, Siegfried H. Reichi, Michael D. Varney, Kanyin E. Zhang, Takuo Kobayashi