Patents by Inventor Eckhard Gunther

Eckhard Gunther has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Pyridopyrazines and the use thereof as kinase inhibitors
    Publication number: 20040266777
    Abstract: The invention relates to novel pyrido[2,3-b]pyrazine derivatives of the general Formula I, their preparation and use as medicaments, in particular for the treatment of malignant and other disorders based on pathological cell proliferations.
    Type: Application
    Filed: May 21, 2004
    Publication date: December 30, 2004
    Inventors: Eckhard Claus, Eckhard Gunther, Irene Seipelt, Ulf R. Rapp, Ludmilla Wixler
  • Novel heteroaryl derivatives and their use as medicaments
    Publication number: 20040132747
    Abstract: The invention relates to novel quinoline derivatives of the formula 1, to their preparation and to their use as medicaments, in particular for treating tumors.
    Type: Application
    Filed: December 19, 2003
    Publication date: July 8, 2004
    Inventors: Peter Emig, Eckhard Gunther, Jurgen Schmidt, Bernd Nickel, Bernhard Kutscher
  • New anthracene derivatives and their use as pharmaceutical preparations
    Publication number: 20040110756
    Abstract: The invention relates to new anthracene derivatives of the general Formula 1 and to their synthesis and use as pharmaceutical preparations, especially for the treatment of a tumor.
    Type: Application
    Filed: July 17, 2003
    Publication date: June 10, 2004
    Inventors: Peter Emig, Eckhard Gunther, Beate Aue, Emmanuel Polymeropoulos, Silke Baasner, Peter Schmidt
  • Use of the disorazoles and their derivatives for the treatment of benign and malignant oncoses
    Publication number: 20040106662
    Abstract: The invention relates to disorazoles of the general formula I, which are employed as medicaments, preferably for the treatment of oncoses, in particular in the case of pharmaceutical resistance to other active compounds and in the case of metastasizing carcinoma. The possible uses are not restricted to oncoses.
    Type: Application
    Filed: August 22, 2003
    Publication date: June 3, 2004
    Inventors: Herbert Irschik, Rolf Jansen, Florenz Sasse, Silke Baasner, Peter Schmidt, Eckhard Gunther
  • Aryl- and heteroarylcarbonylpiperazines and their use for the treatment of benign and malignant oncoses
    Publication number: 20040097734
    Abstract: The invention relates to novel aryl- and heteroarylcarboxamides of the general formula (1), their preparation and use as medicaments, in particular for the treatment of tumors.
    Type: Application
    Filed: June 27, 2003
    Publication date: May 20, 2004
    Inventors: Matthias Gerlach, Peter Emig, Emmanuel Polymeropoulos, Gilbert Muller, Peter Schmidt, Silke Baasner, Eckhard Gunther
  • Use of alkylphosphocholines in combination with antitumor medications for the treatment of benign and malignant oncoses in humans and mammals
    Publication number: 20040097470
    Abstract: The invention relates to the use of alkylphosphocholines in combination with antitumor medicaments for the treatment of benign and malignant oncoses in humans and animals. It is possible in this connection for the alkylphosphocholines to be employed in a combination according to the invention with one or a combination of various approved cytostatics. Preferred alkylphosphocholines are described by the Formula II.
    Type: Application
    Filed: July 30, 2003
    Publication date: May 20, 2004
    Inventors: Jurgen Engel, Eckhard Gunther, Herbert Sindermann
  • Novel heteroaryl derivatives and their use as medicaments
    Publication number: 20040097530
    Abstract: The invention relates to novel quinoline derivatives of the formula 1, to their preparation and to their use as medicaments, in particular for treating tumors.
    Type: Application
    Filed: November 14, 2003
    Publication date: May 20, 2004
    Inventors: Peter Emig, Eckhard Gunther, Jurgen Schmidt, Bernd Nickel, Bernhard Kutscher
  • Heteroaryl derivatives and their use as medicaments
    Patent number: 6706722
    Abstract: The invention relates to novel acridine derivatives of formula 1, to their preparation and to their use as medicaments, in particular for treating tumors.
    Type: Grant
    Filed: July 20, 2001
    Date of Patent: March 16, 2004
    Assignee: Zentaris AG
    Inventors: Peter Emig, Eckhard Günther, Bernd Nickel, Gerhard Bacher, Silke Baasner, Thomas Beckers, Beate Aue
  • Decalactones, method for making, and pharmaceuticals there from
    Publication number: 20030216354
    Abstract: A novel class of decalactones with the general formula (I) and their stereoisomers is disclosed. A method for the synthesis of the decalactones of general formula (I) and the use of the decalactones in pharmaceutical compositions is also described.
    Type: Application
    Filed: May 9, 2002
    Publication date: November 20, 2003
    Inventors: Gerhard Bringmann, Peter Proksch, Ru Angelie Edrada, Markus Heubes, Sudarsono, Eckhard Gunther
  • Heteroary1 derivatives and their use as medicaments
    Patent number: 6638935
    Abstract: The invention relates to novel pyridine derivatives of formula 1, to their preparation and to their use as medicaments, in particular for treating tumors
    Type: Grant
    Filed: July 20, 2001
    Date of Patent: October 28, 2003
    Assignee: Zentaris AG
    Inventors: Peter Emig, Eckhard Günther, Bernhard Kutscher, Bernd Nickel, Jürgen Schmidt, Anita Storch
  • Indolyl-3-glyoxylic acid derivatives having antitumor action
    Publication number: 20030195360
    Abstract: The invention relates to the use of N-substituted indole-3-glyoxylamides of the general formula I as antitumor agents 1
    Type: Application
    Filed: December 4, 2002
    Publication date: October 16, 2003
    Applicant: ASTA Medica Aktiengesellschaft
    Inventors: Bernd Nickel, Istvan Szelenyi, Jurgen Schmidt, Peter Emig, Dietmar Reichert, Eckhard Gunther, Kay Brune, Guillaume Le Baut
  • LHRH antagonists having improved solubility properties
    Patent number: 6627609
    Abstract: The invention relates to peptides which contain N-methylated amino acid units and have improved water solubility. Medicaments in which the peptides according to the invention are contained can be used for the treatment of hormone-dependent tumours and hormone-influenced non-malignant disorders.
    Type: Grant
    Filed: March 14, 2000
    Date of Patent: September 30, 2003
    Assignee: Zentaris AG
    Inventors: Michael Bernd, Bernhard Kutscher, Eckhard Günther, Peter Romeis, Thomas Reissmann, Thomas Beckers
  • United states patent office
    Publication number: 20030023093
    Abstract: The invention relates to the use of N-substituted indole-3-glyoxylamides of the general formula I as antitumor agents 1
    Type: Application
    Filed: March 19, 2001
    Publication date: January 30, 2003
    Applicant: ASTA Medica Aktiengesellschaft
    Inventors: Bernd Nickel, Istvan Szelenyi, Jurgen Schmidt, Peter Emig, Dietmar Reichert, Eckhard Gunther, Kay Brune, Guillaume Le Baut
  • Substituted N-benzylindol-3-ylglyoxylic acid derivatives having antitumor action
    Patent number: 6432987
    Abstract: The invention relates to novel, substituted N-benzyl-indol-3-ylglyoxylic acid derivatives of the following formula and their use for the treatment of oncoses The invention further relates to their physiologically tolerable acid addition salts and if possible their N-oxides.
    Type: Grant
    Filed: December 15, 2000
    Date of Patent: August 13, 2002
    Assignee: Zentaris AG
    Inventors: Eckhard Gunther, Peter Emig, Dietmar Reichert, Guillaume Le Baut, Bernd Nickel, Gerald Bacher
  • Indolyl-3-glyoxylic acid derivatives having antitumor action
    Patent number: 6232327
    Abstract: The invention relates to the use of N-substituted indole-3-glyoxylamides of the general formula I as antitumor agents and to a pharmaceutical composition having antitumor action, characterized in that it contains at least one of the compounds of the general formula 1, if appropriate also in the form of the physiologically tolerable acid addition salts or N-oxides. Furthermore, the invention also includes antitumor agents comprising as active compound one or more N-substituted indole-3-glyoxylamides according to the general formula 1 and, if appropriate, their physiologically tolerable acid addition salts and, if possible, N-oxides and a pharmaceutically utilizable carrier and/or diluent or auxiliary substance in the form of tablets, coated tablets, capsules, solutions for infusion or ampoules, suppositories, patches, powder preparations which can be employed by inhalation, suspensions, creams and ointments.
    Type: Grant
    Filed: April 2, 1999
    Date of Patent: May 15, 2001
    Assignee: Asta Medica Aktiengesellschaft
    Inventors: Bernd Nickel, Istvan Szelenyi, Jürgen Schmidt, Peter Emig, Dietmar Reichert, Eckhard Günther, Kay Brune
  • Lobaplatin trihydrate
    Patent number: 5747534
    Abstract: Cis-?trans-1,2-cyclobutanebis (methylamine)-N,N'!-?(2S)-lactate-O.sup.1,O.sup.2)-platinum (II) trihydrate (lobaplatin trihydrate) and its preparation.
    Type: Grant
    Filed: September 16, 1996
    Date of Patent: May 5, 1998
    Assignee: Asta Medica AG
    Inventors: Eckhard Gunther, Jens-Peter Wulf, Jurgen Engel, Bernhard Kutscher