Abstract: The invention relates to an implant for the human or animal body, which on its outer surface comprises at least one calcium salt that is soluble in a polar liquid. The invention also refers to various methods for the preparation of the preceding implant. The calcium ions contained on the surface of the implant provide said surface with four chemically and biologically advantageous properties: hydrophilicity, protection against atmospheric contamination, a pro-coagulant property and a pro-mineralizing property.

Abstract: Metal structure that serves as an internal support to a dental prosthesis, comprising at least two support posts (1) designed to be attached on respective dental implants (10), and at least one rod (3) for connecting two adjacent support posts (1), where at least one support post (1) comprises at least one protruding element (4a, 4b) that projects from its side, and at least one rod (3) that comprises a first end (5) provided with a blind hole (6) designed to receive a first protruding element (4a) of a support post (1), thus providing an articulated connection that acts like a ball joint, and a longitudinal recess (7) designed to receive a second protruding element (4b) of the adjacent support post (1). This structure is easy to prepare and to assemble.

Abstract: Procedure for obtaining a composition that contains growth factors, which comprises the steps of heat-treating a platelet-rich plasma or the supernatant of a platelet-rich plasma that contains released growth factors in order to increase its temperature, for eliminating the complement and reducing the immunoglobulins present therein, and lyophilizing the plasma or supernatant in order to obtain a final dry composition that can easily be transported, handled and stored, thereby facilitating periodic or chronic treatments with blood compounds. It has been shown that when the final dry composition is resuspended, a once again humid composition is obtained that maintains its biological properties intact.

Abstract: Method of manufacture of a piece designed to be fitted in the area of a dental prosthesis in the mouth of a patient, which comprises creating sugosities on the outer surface of the piece and applying a layer of TiN on the piece. The pieces allow the aesthetic results of the prosthetic treatment to be enhanced. It has also been shown that the manufactured pieces inhibit bacterial adhesion and are biocompatible.

Abstract: Formulation comprising, or derived from, an initial blood composition, wherein the formulation is rich in platelets and/or growth factors and proteins originating from the initial blood composition, and wherein the proteins are in a gelled state. The invention also refers to method for preparing the formulation, comprising the steps of heating and then cooling the initial blood composition at certain temperatures and times. Among other advantages, the formulation in accordance with the invention is biocompatible and biodegradable, presents the desirable biological or medical properties provided by the presence of platelets or growth factors, and also presents high dimensional stability over time.

Abstract: Method for extracting an implant installed in a bone, which comprises the application of a torque on an extraction tool in order to thread it in the interior of the implant until the implant-bone connection is broken, with the specific feature that the torque is applied in phases. In each phase a torque that is increasingly greater than in the previous phase is applied and the application of torque is then eased. This method brings about a gradual and controlled deformation of the head of the implant, with the result that the extraction tool is inserted more deeply into the implant. As a result, higher breakage torques may be applied without damage being caused to the extraction tool.

Abstract: Wrench (1) for providing a maximum torque to an external part, characterised in that it comprises at least one elongated metal part (3) provided with a fixed end (4) and a pusher end (5), and which also comprises a torque-applying head (6) upon which the pusher end (5) acts, wherein the elongated metal part (3) is capable of bending when a torque is applied with the wrench, and wherein the elongated metal part (3) reaches a maximum bending point that determines the maximum torque provided by the wrench (1). The inventive wrench (1) is easier to use than conventional spring-based wrenches as the force required to adjust the torque is minimal and independent of the torque value to which the wrench is adjusted. It is also capable of providing higher torque values.

Abstract: A method for producing a porous calcium polyphosphate structure, which comprises the steps of mixing monocalcium phosphate (MCP) with silicic acid, and sintering the mixture at a predefined temperature or temperatures for a predefined time, after which the porous calcium polyphosphate is obtained. The method allows a porous biomaterial with a controllable porosity to be obtained, and which also has the ability to activate the platelets in a plasma rich in platelets and cause the release of growth factors from the platelets.

Abstract: Method for the preparation of at least one compound with biological properties from blood, where said method is performed in sealed tubes at a pressure below atmospheric pressure, thereby reducing or preventing the bacterial contamination of the compound through handling. The method comprises the repetition, for as many times as is required, of the following steps: connecting a second container that is vacuum-sealed to an extraction device connected in turn to a first container that contains blood separated into fractions, waiting for a period of time until the required fraction(s) is/are transferred, and removing said second container, with it thus being possible to obtain several second containers with different compounds for different medical applications including biological therapies. The steps may be performed in a closed system, without removing the caps of the containers, or alternatively the first container may be opened prior to the introduction of the extraction device.

Abstract: The object of the invention is the treatment of neurodegenerative diseases or other applicable diseases by means of the intranasal administration of a composition obtained from at least one growth-factor-containing blood compound, or by means of a therapeutic substance obtained from said composition, in addition to the composition itself. It is guaranteed that the composition reaches the central nervous system in an effective manner in terms of the treatment, and also in a safe manner for the patient.

Abstract: The invention relates to an implant for the human or animal body, which on its outer surface comprises at least one calcium salt that is soluble in a polar liquid. The invention also refers to various methods for the preparation of the preceding implant. The calcium ions contained on the surface of the implant provide said surface with four chemically and biologically advantageous properties: hydrophilicity, protection against atmospheric contamination, a pro-coagulant property and a pro-mineralising property.

Abstract: Device (1a, 1b, 1c, 1d; 40) for extracting, storing and/or processing blood or other substances of human or animal origin, and for applying blood compounds or other biological compounds, which comprises a body (2; 41) inside which a piston (3; 42) is capable of moving longitudinally and is separable at least in part, where the body (2; 41) is provided with an internal space (9; 51) that may be connected to the outside by means of a conduit (6; 50) at a first end (4; 48) of the body (2; 41), where the body (2; 41) and the piston (3; 43) may be blocked longitudinally in at least one position to allow the creation of different degrees of vacuum. The device has multiple uses and is extremely versatile.

Abstract: The invention relates to an implant for the human or animal body, which on its outer surface comprises at least one calcium salt that is soluble in a polar liquid. The invention also refers to various methods for the preparation of the preceding implant. The calcium ions contained on the surface of the implant provide said surface with four chemically and biologically advantageous properties: hydrophilicity, protection against atmospheric contamination, a pro-coagulant property and a pro-mineralising property.

Abstract: Procedure for obtaining a composition that contains growth factors, which comprises the steps of heat-treating a platelet-rich plasma or the supernatant of a platelet-rich plasma that contains released growth factors in order to increase its temperature, for eliminating the complement and reducing the immunoglobulins present therein, and lyophilizing the plasma or supernatant in order to obtain a final dry composition that can easily be transported, handled and stored, thereby facilitating periodic or chronic treatments with blood compounds. It has been shown that when the final dry composition is resuspended, a once again humid composition is obtained that maintains its biological properties intact.

Abstract: Method for the preparation of at least one compound with biological properties from blood, where said method is performed in sealed tubes at a pressure below atmospheric pressure, thereby reducing or preventing the bacterial contamination of the compound through handling. The method comprises the repetition, for as many times as is required, of the following steps: connecting a second container that is vacuum-sealed to an extraction device connected in turn to a first container that contains blood separated into fractions, waiting for a period of time until the required fraction(s) is/are transferred, and removing said second container, with it thus being possible to obtain several second containers with different compounds for different medical applications including biological therapies. The steps may be performed in a closed system, without removing the caps of the containers, or alternatively the first container may be opened prior to the introduction of the extraction device.

Abstract: A trephine drill bit comprising a body and a tip connected to the body, wherein the tip includes a reduced area having a smaller diameter than the body, the reduced area ending in a stop to indicate when the trephine drill bit should no longer be introduced. A method is also disclosed.

Abstract: Method for expanding bone crest (1) in order to receive the installation of a final dental implant (4), where the bone crest (1) is expanded using a implant-expander, in other words, a biocompatible and osteoconductive piece that has an expander function. The use of an implant-expander (3) to widen the bone crest (1) has the important effect of said implant-expander acting as a support to the bone and therefore helping to consolidate the fracture of the bone crest (1) and the formation of bone around said implant-expander. The bone generated around the implant-expander (3) is therefore of a high quality. The invention also contemplates the optional correction of the angulation of the alveolus during the widening process, so that the final dental implant (4) and the corresponding dental prosthesis are adequately oriented. It is also an object of the invention to provide a specific design for the implant-expander (3).

Abstract: Tool for drilling bone tissue, which has the advantage of having a cutting tip with a flat effective shape that prevents perforation of the Schneider membrane or injury to the dental nerve when drilling close to them. The tool is disposed along an longitudinal axis (7) and comprises a non-cutting main body (1), a narrowed area (2) for retaining bone and a cutting tip (3), which comprises cutting blades (4), each one of which is provided with a front cutting edge (5) substantially perpendicular to the longitudinal axis (7) and a substantially lateral cutting edge (6) that forms an angle of between 0 and 10° with the longitudinal axis (7). Spaces (9) for receiving bone are disposed between the cutting blades (4) and are connected to the narrowed area (2).

Abstract: Set of motor-driven instruments to aid the fixing of dental implants that combines drills (1, 2) and motor-driven osteotomes (4A, 4B, 4C, 4D) of progressive diameters. These have a threaded conical section (9), followed by a threaded cylindrical section (8) and another area (7) to fit the connectors (14, 17) to the surgical motor or a manual extractor.

Abstract: The invention relates to an implant for the human or animal body, which on its outer surface comprises at least one calcium salt that is soluble in a polar liquid. The invention also refers to various methods for the preparation of the preceding implant. The calcium ions contained on the surface of the implant provide said surface with four chemically and biologically advantageous properties: hydrophilicity, protection against atmospheric contamination, a pro-coagulant property and a pro-mineralising property.