Abstract: Aspects of the present disclosure include methods and systems for assaying a sample for an analyte. Methods according to certain embodiments include illuminating a sample with a slit-shaped beam of light, detecting light transmitted through the sample, determining absorbance of the transmitted light at one or more wavelengths and calculating concentration of the analyte based on the absorbance to assay the sample for the analyte. Systems for practicing the subject methods are also described.

Abstract: Aspects of the present disclosure include methods and systems for assaying a sample for an analyte. Methods according to certain embodiments include illuminating a sample with a slit-shaped beam of light, detecting light transmitted through the sample, determining absorbance of the transmitted light at one or more wavelengths and calculating concentration of the analyte based on the absorbance to assay the sample for the analyte. Systems for practicing the subject methods are also described.

Abstract: This document discusses, among other things, systems, devices, and methods for detecting stroke in a patient. A system may comprise a sensor circuit for sensing in a patient at first physiological signal and a second physiological signal or a functional signal. A stroke risk circuit may establish a physiological trend from at least the first physiological signal over time, and generate a stroke risk indicator using the physiological trend and the second physiological or functional signal. Indications of behavioral or cognitive impairment may also be used in stroke risk indicator generation. The system includes an output unit that outputs the stroke risk indicator to a user or a process.

Abstract: This document discusses, among other things, systems and methods for detecting stroke. A system may comprise a sensor circuit for sensing a physiological signal, and a second sensor to detect a physical state change. The physical state change may include a transition in physical activity, posture, or sleep state. A stroke risk circuit may detect, from the sensed physiological signal, a signal indicative of blood pressure surge (BPS) in response to one or more physical state changes. The system may generate a stroke risk indicator indicating a risk of developing an impending stroke event using the detected BPS. The system includes an output unit that outputs the stroke risk indicator to a user or a process.

Abstract: A controller may control a system for extracting liquid water from air comprising a thermal unit, a primary desiccant wheel, and a regeneration fluid path. The controller may comprise a plurality of sensors, a plurality of motors, and a microcontroller coupled to the plurality of sensors and the plurality of motors. The microcontroller may be configured to determine a water extraction efficiency based on at least one signal received from at least one of the plurality of sensors and maximize the water extraction efficiency by adjusting a speed of at least one of the plurality of motors in response to the determined water extraction efficiency. The water extraction efficiency may be a value obtained by multiplying a regeneration fluid flow rate within the regeneration fluid path by an absolute humidity of air on a side of the primary desiccant wheel opposite a side in communication with the thermal unit.

Abstract: The present disclosure provides cytometric methods for the detection of rare target cells in a sample. In certain aspects, the methods and compositions may facilitate the detection of rare target cells, such as circulating tumor cells (CTCs), in a biological sample such as blood. Aspects of the methods include contacting the sample with first and second binding members that specifically bind to a marker of the rare target cell, and cytometrically assaying the sample for the presence of cells comprising bound first and second binding members to detect the rare target cell in the sample. Also provided are systems, compositions, and kits for practicing the subject methods.

Abstract: Aspects of the present disclosure include methods and systems for assaying a sample for an analyte. Methods according to certain embodiments include illuminating a sample with a slit-shaped beam of light, detecting light transmitted through the sample, determining absorbance of the transmitted light at one or more wavelengths and calculating concentration of the analyte based on the absorbance to assay the sample for the analyte. Systems for practicing the subject methods are also described.

Abstract: The present disclosure provides cytometric methods for the detection of rare target cells in a sample. In certain aspects, the methods and compositions may facilitate the detection of rare target cells, such as circulating tumor cells (CTCs), in a biological sample such as blood. Aspects of the methods include contacting the sample with first and second binding members that specifically bind to a marker of the rare target cell, and cytometrically assaying the sample for the presence of cells comprising bound first and second binding members to detect the rare target cell in the sample. Also provided are systems, compositions, and kits for practicing the subject methods.

Abstract: An attachment device is provided comprising at least one fluid filled cavity formed therein. The attachment device is preferably in the form of a carabiner in which at least a portion of the carabiner body is formed of a transparent material such that the fluid filled cavity is visible. In a preferred embodiment an indicia bearing means is visibly disposed within said cavity.

Abstract: An attachment device is provided comprising at least one fluid filled cavity formed therein. The attachment device is preferably in the form of a carabiner in which at least a portion of the carabiner body is formed of a transparent material such that the fluid filled cavity is visible. In a preferred embodiment an indicia bearing means is visibly disposed within said cavity.

Abstract: An attachment device is provided comprising at least one fluid filled cavity formed therein. The attachment device is preferably in the form of a carabiner in which at least a portion of the carabiner body is formed of a transparent material such that the fluid filled cavity is visible. In a preferred embodiment an indicia bearing means is visibly disposed within said cavity.

Abstract: A novelty figurine and carabiner storage assembly is provided. The figurine comprises a head portion, a body portion located proximate to the head portion, and at least one carabiner attachment assembly extending from the body portion for selectively allowing the figurine to be attached to or removed from another item able to receive the attachment assembly. The carabiner attachment assembly comprises at least first and second leg assemblies, with one of the leg assemblies having a selectively openable gate assembly extending therealong. The body portion has at least one substantially hollow interior section and at least one selectively openable door assembly for access into the substantially hollow interior section.

Abstract: Nanometer-scale sensors useful in the detection of biological and chemical entities are formed from a protein rod body portion 41, a magnetic particle 42 affixed to the protein rod body portion 41; and an analyte binding moiety 43 disposed on the protein rod body portion 41 at a location remote from the magnetic particle 42, The analyte binding moiety specifically binds to the analyte 44 to form a sensor-analyte complex. The protein rod body portion may be formed from a tail fiber protein from a T even bacteriophage or a derivative thereof. Interaction of the analyte with the sensor will change the overall shape and size, and thus the ability of the sensor to move within a liquid sample in response to an applied magnetic field. Interaction can therefore be observed as a change in magnetic susceptibility or in relaxation time compared to that of a sensor in the absence of the analyte.

Abstract: A carabiner-type attachment for writing instruments in which the carabiner-type attachment device is attached to the side of said writing instrument or the cap therefor. The attachment device is preferably in the form of a carabiner in which at least a portion of the carabiner body is integral with a pen or pen cap. In alternative embodiments the attachment device is removable from said writing instrument or the cap of the writing instrument.

Abstract: An attachment device is provided comprising at least one fluid filled cavity formed therein. The attachment device is preferably in the form of a carabiner in which at least a portion of the carabiner body is formed of a transparent material such that the fluid filled cavity is visible. In a preferred embodiment an indicia bearing means is visibly disposed within said cavity.

Abstract: A communication device having an attachment device is provided. The communication device comprises front and back portions substantially defining top and bottom ends and left and right sides of the communication device, at least one attachment device engaged therewith and a cavity for receipt therein of the at least one attachment device when the attachment device is in a non-useable position. The attachment device comprising at least one selectively openable gate member for allowing the communication device to be selectively, removably attached to another item. The attachment device being selectively rotatably extendible from the non-useable position within the cavity and selectively rotatably retractable back into the cavity from a useable position, the selective rotatability occurring through one of the left or right sides of the communication device.

Abstract: A carabiner-type attachment for writing instruments in which the carabiner-type attachment device is attached to the side of said writing instrument or the cap therefor. The attachment device is preferably in the form of a carabiner in which at least a portion of the carabiner body is integral with a pen or pen cap. In alternative embodiments the attachment device is removable from said writing instrument or the cap of the writing instrument.

Abstract: A carabiner tool assembly is provided. The tool assembly comprises in one embodiment a body portion for storing a tool having a longitudinal length and a carabiner assembly. The body portion comprises an outside shell forming an interior chamber and an opening extending through the outside shell through to the interior chamber, the opening being sized to be only slightly larger than needed to pass the tool through in a direction along the longitudinal length of the tool. The carabiner assembly comprises a first leg having a selectively openable gate assembly, the first leg extending from a first section of the body portion. A second leg extends from a second section of the body portion and a third leg extends between and connects the first and second legs, wherein the first, second and third legs of the carabiner assembly define another opening. The carabiner assembly can also have only two legs.

Abstract: A novelty figurine and carabiner storage assembly is provided. The figurine comprises a head portion, a body portion located proximate to the head portion, and at least one carabiner attachment assembly extending from the body portion for selectively allowing the figurine to be attached to or removed from another item able to receive the attachment assembly. The carabiner attachment assembly comprises at least first and second leg assemblies, with one of the leg assemblies having a selectively openable gate assembly extending therealong. The body portion has at least one substantially hollow interior section and at least one selectively openable door assembly for access into the substantially hollow interior section.

Abstract: A writing instrument comprises a first end portion having a writing point and a grasping portion, and a second end portion opposite to the first end portion having a plunger member. The plunger member may include an inner member and a non-rigid cover for the inner member. The plunger cover and grasping portion are preferably made of a partially resilient material. The plunger and grasping portion are replaceable without causing damage to the writing instrument, and are preferably matching in appearance. A kit including the writing instrument and, preferably, multiple pairs of plunger covers and grasping portions are also envisioned.