Patents by Inventor Edward Douglas
Edward Douglas has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 6904770Abstract: A multi-function condenser for an air conditioning system includes a first header, a second header, a plurality of tubes, and a conduit. The tubes extend in parallel relationship between the headers for establishing fluid communication between the first header and the second header. The second header includes a header portion and a receiver portion. A conduit extends into and out of and is surrounded by the receiver portion to define a space between the conduit and the receiver portion. Heat is transferred between hot refrigerant flowing in the receiver portion, the header portion, and cooler refrigerant flowing through the conduit as the refrigerant flows through the conduit independently of the refrigerant flowing in the space and in the header portion to increase an overall efficiency of the air conditioning system.Type: GrantFiled: September 3, 2003Date of Patent: June 14, 2005Assignee: Delphi Technologies, Inc.Inventors: John Paul Telesz, Edward Douglas Pettitt, Scott Edward Kent, David A. Southwick
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Patent number: 6768005Abstract: A process for the synthesis of phosphorothioate oligonucleotides is provided which comprises assembling an oligonucleotide bound to a solid support in the presence of acetonitrile; prior to cleaving the oligonucleotide from the solid support removing the acetonitrile; and cleaving the oligonucleotide from the solid support. The process is particularly suited to the large scale synthesis of nucleotides.Type: GrantFiled: December 20, 2000Date of Patent: July 27, 2004Assignee: Avecia LimitedInventors: Ben James Mellor, Donald Alfred Wellings, Mark Edward Douglas
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Publication number: 20030229221Abstract: A process for the synthesis of phosphorothioate oligonucleotides is provided which comprises assembling an oligonucleotide bound to a solid support in the presence of acetonitrile; prior to cleaving the oligonucleotide from the solid support removing the acetonitrile; and cleaving the oligonucleotide from the solid support. The process is particularly suited to the large scale synthesis of nucleotides. The acetonitrile may be removed from the solid support by one or both of drying and by washing with solvents. Preferred washing solvents comprise trialkylamines.Type: ApplicationFiled: June 5, 2003Publication date: December 11, 2003Applicant: AVECIA LIMITEDInventors: Ben James Mellor, Donald Alfred Wellings, Mark Edward Douglas
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Patent number: 6615599Abstract: A thermostatic expansion valve controls a flow of refrigerant. The valve includes a body defining a fluid chamber. A refrigerant inlet is defined within the body. The inlet communicates with the chamber such that the refrigerant can flow through the inlet and into the chamber. First and second outlets are defined within the body. The first outlet communicates with the chamber such that the refrigerant can flow from the chamber to an evaporator during normal and low refrigerant charge. The second outlet communicates with the chamber such that the refrigerant can flow from the chamber to a compressor during low charge. A moveable needle controls the flow of the refrigerant into and out of the body. A notch is defined within the needle such that, during low charge, the refrigerant that flows into the chamber can flow to the second outlet and to the compressor without flowing through the evaporator.Type: GrantFiled: June 26, 2002Date of Patent: September 9, 2003Assignee: Delphi Technologies Inc.Inventors: Edward Douglas Pettitt, John Paul Telesz, Jing Zheng
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Patent number: 6615608Abstract: A multi-function receiver attenuates pressure fluctuations of refrigerant flowing from an evaporator to a compressor in an air conditioning system. The receiver includes a body housing having an inlet for receiving the refrigerant from a condenser and an outlet for sending the refrigerant to the compressor. A cap housing covers the body housing. The receiver also includes first and second ports defined within the cap housing. The first port communicates with the evaporator for sending the refrigerant to the evaporator, and the second port communicates with the evaporator for receiving the refrigerant from the evaporator. An internal wall defines an outer and an inner cavity. The outer cavity communicates with the inlet for receiving the refrigerant from the condenser and with the first port for sending the refrigerant to the evaporator. The inner cavity communicates with the second port to receive the refrigerant from the evaporator and to attenuate the pressure fluctuations.Type: GrantFiled: June 26, 2002Date of Patent: September 9, 2003Assignee: Delphi Technologies, Inc.Inventors: John Paul Telesz, Edward Douglas Pettitt, Jing Zheng
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Patent number: 6616957Abstract: A process is provided for making reduced fat, low fat or no-fat graham-based crackers and flour for the production thereof. The process for making the flour includes providing whole wheat berries having a moisture content of from about 15% by weight to about 20% by weight, radiating the berries with infrared (IR) energy, optionally maintaining the berries at an elevated temperature of from about 80° C. to about 110° C. for a period of time up to about one hour, and cooling, drying and comminuting the treated berries. The moisture content of the berries can be adjusted by moistening or tempering the berries prior to treatment with IR energy. The moisture content, optional tempering conditions, amount of irradiated IR energy, the elevated temperature, and the various treatment periods are sufficient to inactivate lipase and lipoxygenase in the berries yet insufficient to gelatinize more than about 20% of the starch in the berries.Type: GrantFiled: November 28, 2000Date of Patent: September 9, 2003Assignee: Kraft Foods Holdings, Inc.Inventors: Carolyn Louise Wilhelm, Tim Michael Adrianson, Diane Louise Gannon, Edward Douglas Howey, Harold Ira Levine, Patricia Ann Mozeke, Louise Slade
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Patent number: 6615610Abstract: A concentric tubing apparatus prevents heat gain in an air conditioning system. The heat gain results from heat generated in an engine compartment of a vehicle. To accomplish this, the tubing apparatus includes a first and second refrigerant tubes. The first refrigerant tube is in fluid communication with a receiver and an evaporator of the air conditioning system to accommodate the flow of the refrigerant from the receiver to the evaporator, and the second refrigerant tube is in fluid communication with the receiver and the evaporator to accommodate the flow of the refrigerant from the evaporator to the receiver. The second refrigerant tube is disposed concentrically about the first refrigerant tube such that the second refrigerant tube insulates the refrigerant flowing in the first refrigerant tube from the heat generated in the engine compartment. Thus, heat gain in the refrigerant flowing in the first refrigerant tube to the evaporator is prevented.Type: GrantFiled: June 26, 2002Date of Patent: September 9, 2003Assignee: Delphi Technologies, Inc.Inventors: Edward Douglas Pettitt, John Paul Telesz, Jing Zheng
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Patent number: 6562960Abstract: An oligonucleotide analogue having 10 to 200 natural and/or synthetic nucleoside units, linked by internucleoside linkages, at least one of the internucleoside linkages being of formula where the indicated methylene group is attached to a 3′ carbon atom of a nucleoside, the indicated oxygen atom is attached to a 5′-carbon atom of an adjacent nucleside, R1 is hydrogen, hydroxy, O—, thiol, S—, —NH2 or a group of formula R1a, —OR1a, —SR1a, —NHR1b, or —NR1bR1c wherein R1a is an unsubstituted or substituted C1 to C10 alkyl, C2 to C10 alkenyl, C3 to C8 cycloalkyl, C6 to C10 aryl or C7 to C13 aralkyl group; and R1b and R1c are each independently an unsubstituted or substituted C1 to C10 alkyl, C2 to C10 alkenyl, C3 to C8 cycloalkyl, C6 to C10 aryl or C7 to C13 aralkyl group or R1b and R1c together with the nitrogen atom to which they are attached denote a five- or six-membered heterocyclic ring, and X is oxygen or sulfur.Type: GrantFiled: October 9, 1998Date of Patent: May 13, 2003Assignee: ISIS Pharmaceuticals, Inc.Inventors: Anthony David Baxter, Stephen Paul Collingwood, Mark Edward Douglas, Roger John Taylor
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Publication number: 20020111479Abstract: A process for the synthesis of phosphorothioate oligonucleotides is provided which comprises assembling an oligonucleotide bound to a solid support in the presence of acetonitrile; prior to cleaving the oligonucleotide from the solid support removing the acetonitrile; and cleaving the oligonucleotide from the solid support. The process is particularly suited to the large scale synthesis of nucleotides.Type: ApplicationFiled: December 20, 2000Publication date: August 15, 2002Inventors: Ben James Mellor, Donald Alfred Wellings, Mark Edward Douglas
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Patent number: 6329519Abstract: A compound of formula (I) wherein B1 is a radical of a nucleoside base, R1 is hydrogen or a hydroxy-protecting group, R2 is hydrogen, hydroxy or a 2′-nucleoside-modifying atom or group, R3 is an unsubstituted or substituted C1 to C10 alkyl, C2 to C10 alkenyl, C4 to C10 cycloalkylalkyl, C6 to C10 aryl or C7 to C13 aralkyl group, and Z is halogen or a group of formula (II) where R4 and R5 are each independently an unsubstituted or substituted C1 to C10 alkyl, C2 to C10 alkenyl, C4 to C10 cycloalkylalkyl, C6 to C10 aryl or C7 to C13 aralkyl group, or R4 is said group and R5 is hydrogen or R4 and R5 together with the nitrogen atom to which they are attached denote a five- to thirteen-membered heterocyclic ring, or Z is a group of formula (III): Nuc-O—, where Nuc is the residue of a natural or synthetic nucleoside or oligonucleotide after removal of a 5′-hydroxyl group therefrom attached through a 5′-methylene thereof to the indicated oxygen atom.Type: GrantFiled: March 15, 1999Date of Patent: December 11, 2001Assignee: ISIS Pharmaceuticals, Inc.Inventors: Stephen Paul Collingwood, Heinz Ernst Moser, Karl-Heinz Altmann, Mark Edward Douglas
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Patent number: 6301262Abstract: A computer implemented method is described for determining message transmission time in a time division multiple access communications network.Type: GrantFiled: May 29, 1998Date of Patent: October 9, 2001Inventor: Edward Douglas Peterson
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Patent number: 6220122Abstract: A fastener driving system and a fastener holding tool therefor having a shank and a resilient retainer with a bore therethrough coupled to a first end portion of the shank. A first end of the resilient retainer and a portion of the resilient retainer bore protrudes axially beyond the first end of the shank. In some embodiments, an annular chamfer is disposed on the resilient retainer between a first end and the bore thereof. The system includes a fastener having a shaft with a head formed on a trailing end portion thereof. The fastener head diameter is greater than the retainer bore diameter of the resilient retainer protruding axially beyond the first end of the shank to engage and retain the fastener.Type: GrantFiled: October 20, 1999Date of Patent: April 24, 2001Assignee: Illinois Tool Works IncInventors: David J. Forsell, Edward Douglas Yates
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Patent number: 5697176Abstract: An improved golf cart display panel comprises an elongated plastic body forming a frame through which a color graphic representation of holes on a golf course can be viewed. The plastic body is sized to be mounted to the golf cart extending between the upstanding roof support posts on the front of the cart with the graphic display being presented to a golfer in the cart. The graphic display includes areas for advertising copy allowing sponsors to advertise their products and services to golfers riding in the cart.Type: GrantFiled: November 25, 1994Date of Patent: December 16, 1997Inventors: James Clifford Kuni, Jr., Edward Douglas Hughes
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Patent number: 4572378Abstract: Apparatus and method for separating discrete items of different materials from a mixture. The mixed items fall vertically from a feeder device onto a plate spinning about a vertical axis. According to their difference in material, the items rebound with different trajectories so that they land on separate receiving surfaces lying at different radii from the axis. The receiving surfaces may be stationary or maybe vibratable, so that items received by them are conveyed along them by vibration to collection points.Type: GrantFiled: September 24, 1984Date of Patent: February 25, 1986Assignee: National Research Development CorporationInventors: Edward Douglas, Maurice I. Webb
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Patent number: 4066651Abstract: Novel 1,2-dihydro-2-oxoquinol-4-ylalkanoic acid derivatives bearing a variety of substituents on the quinoline nucleus but including, at position 1, an aromatic radical linked directly or through a C.sub.1-4 -alkylene or a C.sub.2-4 -alkenylene radical. Representative compounds of the invention are 1-(3,4-dichlorobenzyl)-3-methyl-1,2-dihydro-2-oxoquinol-4-ylacetic acid and .alpha.-(1-benzyl-1,2-dihydro-2-oxoquinol-4-yl)propionic acid. The compounds possess anti-inflammatory or analgesic properties, or are inhibitors of the enzyme aldose reductase.Type: GrantFiled: March 1, 1976Date of Patent: January 3, 1978Assignee: Imperial Chemical Industries LimitedInventors: David Robert Brittain, Edward Douglas Brown, Walter Hepworth, Gilbert Joseph Stacey
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Patent number: 4053165Abstract: This invention relates to a piston ring having two ring elements and a spacer-expander the latter including a series of interconnected parts each comprising two pairs of inwardly directed limbs, the inner ends of which are in contact with and resiliently load the ring elements, and a spacer element which extends transversely to space apart the ring elements at the outer periphery.Type: GrantFiled: December 17, 1975Date of Patent: October 11, 1977Assignee: Hepworth & Grandage LimitedInventor: Edward Douglas Hartley
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Patent number: 4004021Abstract: The disclosure relates to novel pentanor prostaglandin analogues, for example 15-(5-chloroindan-2-yl)-9.alpha.,11.alpha.,15-trihydroxy-16,17,18,19,20-pe ntanor-5-cis,13-trans-prostadienoic acid and 15-(5-chloroindan-2-yl)-11.alpha.,15-dihydroxy-9-oxo-16,17,18,19,20-pentan or-5-cis,13-trans-prostadienoic acid and the 1-ester and 1-alcohol derivatives thereof, to a process for their manufacture, to compositions containing them, and to their use in a method of inducing luteolysis.Type: GrantFiled: December 18, 1975Date of Patent: January 18, 1977Assignee: Imperial Chemical Industries LimitedInventors: Jean Bowler, Edward Douglas Brown, Peter Robert Marsham, Edward Raymond Halstead Walker
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Patent number: 3962045Abstract: A pyrolysing vessel in which the inlets and outlets for the charge and the pyrolysing gas are so arranged that charge and gas pass through the vessel along paths that meet substantially at right angles. The charge may descend vertically, and the vessel may taper outwardly and downwardly to aid this descent. The gas may enter and leave the vessel through grilles that can be oscillated to further aid the descent. Pyrolysing plant including the vessel may include means to take a fraction of the gas at the outlet and recycle it through a heater to the gas inlet.Type: GrantFiled: August 28, 1974Date of Patent: June 8, 1976Assignee: National Research Development CorporationInventors: Edward Douglas, Terence Walsh
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Patent number: 3953502Abstract: The disclosure relates to novel pentanor prostaglandin analogues, for example 15-(5-chloroindan-2-yl)-9.alpha.,11.alpha.,15-trihydroxy-16,17,18,19,20-pe ntanor-5-cis, 13-trans-prostadienoic acid and 15-(5-chloroindan-2-yl)-11.alpha.,15-dihydroxy-9-oxo-16,17,18,19,20-pentan or-5-cis,13-trans-prostadienoic acid and the 1-ester and 1-alcohol derivatives thereof, to a process for their manufacture, to compositions containing them, and to their use in a method of inducing luteolysis.Type: GrantFiled: January 17, 1974Date of Patent: April 27, 1976Assignee: Imperial Chemical Industries LimitedInventors: Jean Bowler, Edward Douglas Brown, Peter Robert Marsham, Edward Raymond Halstead Walker
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Patent number: D506611Type: GrantFiled: March 2, 2004Date of Patent: June 28, 2005Assignee: Dynapaq, LLCInventors: Christopher Mathew Hiller, Brad Alan Mart, Daniel Joseph Ahern, Wesley Edward Douglas, Timothy Edward Pressley