Patents by Inventor Edward J. Moler

Edward J. Moler has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20170316153
    Abstract: A method of determining risk of diabetes is provided. In one embodiment, the method comprises: a) measuring the levels of a plurality of biomarkers in a blood samples obtained from a patient, wherein the plurality of biomarkers comprises at least five of the following biomarkers: glucose, adiponectin, CRP, IL2RA, ferritin, insulin and HbA1c; b) calculating a diabetes risk score for the patients using the levels and, optionally, patient age and/or gender. Results obtained from performing the assay on a reference population are similar or identical to those obtained using Formula I.
    Type: Application
    Filed: July 18, 2017
    Publication date: November 2, 2017
    Inventors: Michael P. McKenna, Michael Rowe, Edward J. Moler, JR., Robert W. Gerwien
  • Patent number: 9740819
    Abstract: A method of determining risk of diabetes is provided. In one embodiment, the method comprises: a) measuring the levels of a plurality of biomarkers in a blood samples obtained from a patient, wherein the plurality of biomarkers comprises at least five of the following biomarkers: glucose, adiponectin, CRP, IL2RA, ferritin, insulin and HbAIc; b) calculating a diabetes risk score for the patients using the levels and, optionally, patient age and/or gender. Results obtained from performing the assay on a reference population are similar or identical to those obtained using Formula I.
    Type: Grant
    Filed: October 28, 2010
    Date of Patent: August 22, 2017
    Assignee: TRUE HEALTH IP LLC
    Inventors: Michael P. McKenna, Michael Rowe, Edward J. Moler, Jr., Robert W. Gerwien
  • Publication number: 20120322065
    Abstract: The invention relates to methods of using nanoreactor technology for sample analysis in microfluidic systems.
    Type: Application
    Filed: May 22, 2012
    Publication date: December 20, 2012
    Inventors: Michael S. Urdea, Theodore M. Tarasow, Edward J. Moler
  • Publication number: 20120308569
    Abstract: The present invention provides polynucleotides, as well as polypeptides encoded thereby, that are differentially expressed in cancer cells. These polynucleotides are useful in a variety of diagnostic and therapeutic methods. The present invention further provides methods of reducing growth of cancer cells. These methods are useful for treating cancer.
    Type: Application
    Filed: June 7, 2012
    Publication date: December 6, 2012
    Applicant: NOVARTIS VACCINES & DIAGNOSTICS, INC.
    Inventors: Vivien W. CHAN, Jaime Escobedo, Pablo Dominguez Garcia, Rhonda Hansen, Joerg Kaufmann, Giulia C. Kennedy, George Lamson, Edward J. Moler, Filippo Randazzo, Christoph Reinhard, Julie Sudduth-Klinger
  • Publication number: 20120309030
    Abstract: A method of determining risk of diabetes is provided. In one embodiment, the method comprises: a) measuring the levels of a plurality of biomarkers in a blood samples obtained from a patient, wherein the plurality of biomarkers comprises at least five of the following biomarkers: glucose, adiponectin, CRP, IL2RA, ferritin, insulin and HbAIc; b) calculating a diabetes risk score for the patients using the levels and, optionally, patient age and/or gender. Results obtained from performing the assay on a reference population are similar or identical to those obtained using Formula I.
    Type: Application
    Filed: October 28, 2010
    Publication date: December 6, 2012
    Applicant: TETHYS BIOSCIENCE, INC.
    Inventors: Michael P. McKenna, Michael Rowe, Edward J. Moler, JR., Robert W. Gerwien
  • Patent number: 8221983
    Abstract: The present invention provides polynucleotides, as well as polypeptides encoded thereby, that are differentially expressed in cancer cells. These polynucleotides are useful in a variety of diagnostic and therapeutic methods. The present invention further provides methods of reducing growth of cancer cells. These methods are useful for treating cancer.
    Type: Grant
    Filed: March 16, 2010
    Date of Patent: July 17, 2012
    Assignee: Novartis Vaccines and Diagnostics, Inc.
    Inventors: Vivien W. Chan, Jaime Escobedo, Pablo Dominguez Garcia, Rhonda Hansen, Joerg Kaufmann, Giulia C. Kennedy, George Lamson, Edward J. Moler, Filippo Randazzo, Christoph Reinhard, Julie Sudduth-Klinger
  • Publication number: 20100233187
    Abstract: The present invention provides polynucleotides, as well as polypeptides encoded thereby, that are differentially expressed in cancer cells. These polynucleotides are useful in a variety of diagnostic and therapeutic methods. The present invention further provides methods of reducing growth of cancer cells. These methods are useful for treating cancer.
    Type: Application
    Filed: March 16, 2010
    Publication date: September 16, 2010
    Inventors: Vivien W. Chan, Jaime Escobedo, Pablo Dominguez Garcia, Rhonda Hansen, Joerg Kaufmann, Giulia C. Kennedy, George Lamson, Edward J. Moler, Filippo Randazzo, Christoph Reinhard, Julie Sudduth-Klinger
  • Patent number: 7700359
    Abstract: The present invention provides polynucleotides, as well as polypeptides encoded thereby, that are differentially expressed in cancer cells. These polynucleotides are useful in a variety of diagnostic and therapeutic methods. The present invention further provides methods of reducing growth of cancer cells. These methods are useful for treating cancer.
    Type: Grant
    Filed: September 22, 2004
    Date of Patent: April 20, 2010
    Assignee: Novartis Vaccines and Diagnostics, Inc.
    Inventors: Vivien W. Chan, Jaime Escobedo, Pablo Dominguez Garcia, Rhonda Hansen, Joerg Kaufmann, Giulia C. Kennedy, George Lamson, Edward J. Moler, Filippo Randazzo, Christoph Reinhard, Julie Sudduth-Klinger
  • Publication number: 20100075436
    Abstract: The invention relates to methods of using nanoreactor technology for sample analysis in microfluidic systems.
    Type: Application
    Filed: May 6, 2009
    Publication date: March 25, 2010
    Inventors: Michael S. URDEA, Theodore M. TARASOW, Edward J. MOLER
  • Patent number: 5167485
    Abstract: A joint connection for abutting, circumferentially extending segments in a gas turbine engine, such as turbine nozzle segments, includes a sealing member which is insertable between longitudinally extending slots formed in the abutting side edges of two adjacent segments. The segments are each formed with a number of grooves which are longitudinally spaced along the length of the slots therein, and which extend beneath the sealing member carried within the slots. A cooling air flow path is thus formed extending from one side of the sealing member, into the longitudinal slot of each segment and then through the grooves to the opposite side of the sealing member so that the entire joint connection or seal region between the abutting side edges of the segments is cooled.
    Type: Grant
    Filed: April 6, 1992
    Date of Patent: December 1, 1992
    Assignee: General Electric Company
    Inventor: John H. Starkweather