Abstract: In aspects, the invention provides novel compositions and methods for dominant inhibition of viral infection.

Abstract: This invention relates to novel compounds according to Formula (I) which are antagonists of MrgX2, to pharmaceutical compositions containing them, and to their use in therapy for the treatment of MrgX2-mediated diseases and disorders.

Abstract: Exemplary semiconductor processing chamber faceplates may include a body having a first surface and a second surface opposite the first surface. The body may define a plurality of apertures that extend through one or both of the first surface and the second surface. The faceplates may include a heater disposed within an interior of the body. The faceplates may include a first RF mesh disposed between the heater and the first surface. The faceplates may include a second RF mesh disposed between the heater and the second surface. The first RF mesh and the second RF mesh may be coupled together and form a Faraday cage about the heater.

Abstract: An AC-DC converter includes an AC voltage source, a rectifier, and a rectifier control circuit. The rectifier includes a field effect transistor (FET) having a source, a drain, and a gate. The drain of the FET is coupled to the AC voltage source, and the source is coupled to ground. The rectifier control circuit is coupled to the gate of the FET. The rectifier control circuit is configured to provide a ramp voltage to regulate the FET after the AC voltage source is turned off.

Abstract: Embodiments of a vehicle interior system are disclosed. In one or more embodiments, the system includes a base with a curved surface, and a display or touch panel disposed on the curved surface. The display includes a cold-bent glass substrate with a thickness of 1.5 mm or less and a first radius of curvature of 20 mm or greater, and a display module and/or touch panel attached to the glass substrate having a second radius of curvature that is within 10% of the first radius of curvature. Methods for forming such systems are also disclosed.

Abstract: A display may have a pixel array such as a liquid crystal pixel array. The pixel array may be illuminated with backlight illumination from a direct-lit backlight unit. The backlight unit may include an array of light-emitting diodes (LEDs) on a printed circuit board. The display may have a notch to accommodate an input-output component. Reflective layers may be included in the notch. The backlight may include a color conversion layer with a property that varies as a function of position. The light-emitting diodes may be covered by a slab of encapsulant with recesses in an upper surface.

Abstract: In some embodiments, a method for processing an optical fiber includes: drawing an optical fiber through a draw furnace, conveying the optical fiber through a flame reheating device downstream from the draw furnace, wherein the flame reheating device comprises one or more burners each comprising: a body having a top surface and an opposing bottom surface, an opening within the body extending from the top surface through the body to the bottom surface, wherein the optical fiber passes through the opening, and one or more gas outlets within the body; and igniting a flammable gas provided by the one or more gas outlets to form a flame encircling the optical fiber passing through the opening, wherein the flame heats the optical fiber by at least 100 degrees Celsius at a heating rate exceeding 10,000 degrees Celsius/second.

Abstract: Methods, systems, and computer programs are presented for providing stored procedures stored within a database to invoke specified functionality in a cloud data platform. A response to a database query is received at a compute node of a cloud data platform. A java database connectivity (JDBC) instance executing within a sandbox process converts the response into a remote procedure call. The remote procedure call is provided to a stored procedure executing within the sandbox process as the response to the database query.

Abstract: Interleukin-2 (IL-2) conjugates comprising at least one or more amino acid substitutions that bias binding to the IL-2 receptor ??c dimer over binding the IL-2 receptor ???c trimer and a non-natural amino acid at or near the N-terminus conjugated to a water-soluble polymer are described. The IL-2 conjugates are useful for treatment and prevention of cell proliferation and cancer in a patient.

Abstract: The present disclosure relates to an electrode for CO2 electroreduction in an acidic electrolyte comprising cation species, the electrode comprising: a substrate, a metal-based catalyst material, and a cation-augmenting material; wherein the cation-augmenting material comprises an acidic group exchanging protons with the cation species of the acidic electrolyte so as to increase a concentration of the cation species at a surface of the electrode.

Abstract: Support assemblies for supporting a light-emitting diode (LED) lamp, which may be a heavy LED lamp. In an embodiment, a support assembly includes a frame having a ring and configured to be detachably connected to a front cover of an LED lamp. The support assembly also includes a plurality of position modules uniformly distributed around the periphery of the ring, wherein the position modules may cover at least a portion of the front cover of the LED lamp, and at least one support leg attached to the frame. The at least one support leg supports the frame and an inserted LED lamp on at least one support surface, and at least one support leg is slidably coupled to the frame and adjustable to provide a support length between the frame and the at least one support surface.

Abstract: A technique is provided for determining a loss risk assessment score for a vehicle trip. The technique includes, at a vehicle, a computing device receiving first information indicative of operation of the vehicle. The technique also includes, at the vehicle, the computing device receiving second information indicative of an environment at a particular location and time. The computing device correlates the first information and the second information to generate a data set. The technique also includes determining a score for the vehicle trip based at least in part upon the generated data set.

Abstract: The present disclosure is directed to methods and compositions for the prediction and treatment of immunotherapy-induced toxicities, as well as improved methods for the treatment of cancer with immunotherapies.

Abstract: Provided is a system and methodology which enhances the readability of barcodes using machine learning techniques wherein a model is trained using exemplary data and the resulting model is used in production to increase the chances of successfully capturing the data in a barcode notwithstanding that the barcode may be of low quality. According to the teachings of the present invention, the system is trained using large quantities of synthetic personal information associated with barcodes. Once the system is placed into production, the trained model is applied as against newly identified barcodes to enhance the readability of the original barcode based on features associated with the trained model.

Abstract: A method by one or more computing devices to standardize and centralize data movement between systems. The method includes receiving and storing data source information for a logical data source including authentication and authorization information for accessing a plurality of source systems that store data associated with the logical data source, schema information for a first schema used by a first one of the plurality of source systems to store data associated with the logical data source, and process information for a process including job information for a first job of the process that is for importing data associated with the logical data source from the first source system to a staging area. The method further includes executing the process according to the process information for the process.

Abstract: A method by one or more computing devices to standardize and centralize data movement between systems. The method includes receiving and storing data source information for a logical data source including authentication and authorization information for accessing a plurality of source systems that store data associated with the logical data source, schema information for a first schema used by a first one of the plurality of source systems to store data associated with the logical data source, and process information for a process including job information for a first job of the process that is for importing data associated with the logical data source from the first source system to a staging area. The method further includes executing the process according to the process information for the process.

Abstract: A system and method of multiview style transfer apply a style transfer to individual views of a multiview image in a way that produces consistent results across all images. In some embodiments, the multiview style transfer includes receiving first and second images representative of first and second perspectives of a scene and first and second disparity maps corresponding to the first and second images, generating a first stylized image, generating a stylized shifted image based on the first stylized image and the first disparity map, generating a second stylized image based on a guided filter of the stylized shifted image and the second image, and generating a first and second stylized image based on the stylized shifted images and the disparity maps.

Abstract: A method of developing a product is provided that includes generating a digital system model (DSM) that describes the product and a manufacturing process for the product, and generating a digital twin (DTw) of an instance of a component of the manufacturing process, the DTw including a digital replica of the instance. The method includes receiving attribute data for attributes of process/process characteristics subject to sources of variation that affect product quality. The digital replica is executed with input of the attribute data, and thereby updating the DTw to replicate the instance of the component of the manufacturing process as performed. A data analysis of the manufacturing process is performed based on the DTw as updated, and the manufacturing process is modified based on the data analysis to reduce variability in one or more product characteristics. The DTws of multiple instances may be used to generate further improvement.

Abstract: A system for monitoring the health and safety of recumbent individuals. In some embodiments, the bed monitor system comprises a wired or wireless sensor mat which may be positioned upon a bed mattress and underneath a bedsheet. Multiple RFID tag sensors embedded within the sensor mat can detect physical, bodily, and environmental attributes and transmit this information to a controller box for further processing. Turn regiment, prohibited body positions, imminent fall danger, and bed occupancy may therefore be tracked and updated accordingly. In some embodiments, the system can dynamically generate positional images of a body proximate to the sensor mat in order to identify adverse conditions requiring attention. Incontinence discharges can also be detected by sensors and algorithms which can differentiate urinary from fecal incontinence events. Various embodiments of the system are portable, allowing for a rapid set-up within hospital venues and within other care facilities.

Abstract: Systems, methods, and non-transitory computer-readable media can determine an interaction flow for interacting with a given user, the interaction flow including a set of candidate components that are eligible to be dynamically presented to the user. A set of features associated with the user can be determined. At least one first component from the set of candidate components can be determined based at least in part on the set of features associated with the user. The at least one first component can be provided for presentation to the user.