Abstract: A system and method for document transformation is provided. An address is received. A document set is generated based on the address. Each document includes data fields and an identifier for each data field. A transaction number is assigned to the document set. Data values are received for population of the data fields in one of the documents. The data values and the identifier for the data field in which each data value is populated is stored with the transaction number. The remaining documents are populated. One of the identifiers is identified for one of the data fields in one of the remaining documents. One of the data fields is determined in one of the remaining documents. The data value associated with the data field is identified based on the identifier and the transaction number. The data fields in the remaining documents are populated with the determined data value.

Abstract: A system and method for document transformation and recordation is provided. Documents for a transaction of real property are identified based on a jurisdiction in which the real property is located. Each document includes a plurality of data fields and each data field is associated with a data field identifier. A data value is received in at least one of the data fields of one or more of the documents. The data fields in the documents associated with the data field identifiers that match the data field identifiers of the data fields in which the data values are received are identified. The identified data fields are automatically populated with the data values based on the data field identifiers associated with the data values. A completeness rule is applied to the documents by verifying whether all required documents for completing the transaction in the jurisdiction are satisfied by the documents.

Abstract: The present invention relates to novel novel monocyclic and bicyclic ring system substituted carbanucleoside analogues of Formula (I) wherein the variables have the meaning defined in the claims. The compounds according to the present invention are useful as PRMT5 inhibitors. The invention further relates to pharmaceutical compositions comprising said compounds as an active ingredient as well as the use of said compounds as a medicament.

Abstract: The present invention relates to a method of treating or preventing DNA damage in a cell or cellular senescence of a cell or induction of the senescence associated secretory phenotype (SASP) in a cell, or for treating or preventing the effects of aging, or for preventing or treating cellular senescence and/or induction of SASP associated with high caloric intake or obesity, or for reducing the side effects of chemotherapy, radiotherapy, corticoid treatment, anti-retroviral treatment, or PPAR? agonist treatment comprising administering an effective amount of an NAD+ agonist.

Abstract: The disclosure provides trispecific and/or trivalent binding proteins comprising four polypeptide chains that form three antigen binding sites that specifically bind one or more target proteins, wherein a first pair of polypeptides forming the binding protein possess dual variable domains having a cross-over orientation and wherein a second pair of polypeptides forming the binding protein possess a single variable domain. The disclosure also provides methods for making trispecific and/or trivalent binding proteins and uses of such binding proteins.

Abstract: In some examples, an apparatus may include a backlight unit (BLU) including an electronic integrated circuit layer, a photonic integrated circuit layer, a color conversion module, and a display interface layer. In some examples, a BLU may include at least one laser or may be configured to receive laser light from at least one external laser source. Laser light may be transmitted towards a portion of the display interface layer using the photonic integrated circuit. Color conversion modules may be used to convert the laser light into one or more desired colors. Example apparatus may be used in head-mounted devices such as augmented reality and/or virtual reality devices. Other devices, methods, systems, and computer-readable media are also disclosed.

Abstract: Systems and methods for document transformation and recordation are provided. Documents for a transaction of real property are identified based on a jurisdiction in which the real property is located. Each document includes a plurality of data fields and each data field is associated with a data field identifier. A data value is received in at least one of the data fields of one or more of the documents. The data fields in the documents associated with the data field identifiers that match the data field identifiers of the data fields in which the data values are received are identified. The identified data fields are automatically populated with the data values based on the data field identifiers. Completeness rules are applied to the documents by verifying all required documents for completing the transaction in the jurisdiction are satisfied. Documents or information pertaining the documents can be stored in a blockchain.

Abstract: Support assemblies for supporting a light-emitting diode (LED) lamp, which may be a heavy LED lamp. In an embodiment, a support assembly includes a frame having a ring and configured to be detachably connected to a front cover of an LED lamp. The support assembly also includes a plurality of position modules uniformly distributed around the periphery of the ring, wherein the position modules may cover at least a portion of the front cover of the LED lamp, and at least one support leg attached to the frame. The at least one support leg supports the frame and an inserted LED lamp on at least one support surface, and at least one support leg is slidably coupled to the frame and adjustable to provide a support length between the frame and the at least one support surface.

Abstract: A vending machine adapted for dispensing at least one pre-packaged food product includes a microwave oven. The microwave oven includes a magnetron that emits microwave electromagnetic radiation, a housing that defines a microwave cavity for receiving the food product. The housing defines a first opening to allow passage of the pre-packaged food product between outside of the microwave cavity and inside of the microwave cavity. The microwave oven also includes a first chain door that selectively covers the first opening so as to prevent the microwave electromagnetic radiation from escaping the housing through the first opening.

Abstract: A multi-tier blockchain-based method for document transformation and accountability is provided. A set of transaction documents for a transfer of real property is received and the transfer is recorded via a multi-tier blockchain. The set of transaction documents is stored on a ledger associated with two or more supernodes in a tier of supernodes. A cryptographic hash of the set of transaction documents is provided to a different tier of nodes and stored on a ledger associated with each of the nodes in the different tier. A number of supernodes in the tier is larger than a number of the nodes in the different tier.

Abstract: A blockchain-based method for purchase document transformation and accountability is provided. Offer documents for a real estate transaction are maintained and a review of the documents is performed by comparing populated fields of each document with offer compliance guidelines. When the fields of the offer documents comply with the offer compliance guidelines, the offer documents are grouped as an offer for the transaction. Public and private documents from the offer are formed as separate data blocks, which are provided to a tier of supernodes. Each data block is added to a ledger of transactions via one of the supernodes. A copy of each data block is stored on each of the supernodes. An immutable record of each data block is transmitted from the supernode to a tier of network nodes and the immutable record of each data block is committed to a blockchain via each of the network nodes.

Abstract: A system and method for document transformation is provided. An address is received. A document set is generated based on the address. Each document includes data fields and an identifier for each data field. A transaction number is assigned to the document set. Data values are received for population of the data fields in one of the documents. The data values and the identifier for the data field in which each data value is populated is stored with the transaction number. The remaining documents are populated. One of the identifiers is identified for one of the data fields in one of the remaining documents. One of the data fields is determined in one of the remaining documents. The data value associated with the data field is identified based on the identifier and the transaction number. The data fields in the remaining documents are populated with the determined data value.

Abstract: A location-based application, such as a parallel reality game, may receive, from a client device of a user of the application, location data representing the user's position in the real-world. In one embodiment, a game platform associated with the application writes location data derived from the received location data to each of a plurality of retention tables, each storing the location data at a different level of granularity and for a different retention period. Upon expiration of a retention period for a first retention table, the game platform anonymizes the location data and transfers the anonymized data to a second retention table storing the data at a lower level of granularity. The game platform repeats this process until expiration of the retention period for the table having the lowest level of granularity before deleting the location data from storage.

Abstract: A single-tier blockchain-based system and method for document transformation and accountability is provided. Transaction documents including document templates relating to a transfer of real property are maintained. Each template includes form elements. The form elements are each associated with a data field identifier and a data value. A data model is maintained for the transaction documents and includes the data field identifiers and the data values for the form elements. A request is received for the transaction documents. The form elements of the transaction documents are automatically populated with the data values via the data model in response to the request. Compliance checking is performed on the data values populating the form elements. A cryptographic hash of the transaction documents is committed to a blockchain copy stored by one or more network nodes in a single-tier when no errors are identified in the data values during the compliance checking.

Abstract: A method includes selecting, by one or more servers, a digital component to be presented in an application executed at a client device; obtaining, by the one or more servers, attributes of the digital component, including at least one or more of a destination network location to which the digital component redirects users in response to interaction with the digital component and a reporting network location to which the interaction with the digital component is reported; after selecting the digital component and obtaining the attributes of the digital component, selecting, by the one or more servers and based on the obtained attributes, a config file that specifies a set of operations to be performed by the client device that presents the digital component; and transmitting, to the client device, a payload that includes information specifying the digital component to be presented in the application and the config file that, upon execution by the client device, causes the client device to perform the set of op

Abstract: A system and method for document transformation and recordation is provided. Documents for a transaction of real property are identified based on a jurisdiction in which the real property is located. Each document includes a plurality of data fields and each data field is associated with a data field identifier. A data value is received in at least one of the data fields of one or more of the documents. The data fields in the documents associated with the data field identifiers that match the data field identifiers of the data fields in which the data values are received are identified. The identified data fields are automatically populated with the data values based on the data field identifiers associated with the data values. A completeness rule is applied to the documents by verifying whether all required documents for completing the transaction in the jurisdiction are satisfied by the documents.

Abstract: The present invention relates to methods of increasing vascular density and/or blood flow in tissue of a subject, and to increasing exercise capacity of a subject, the methods include administering to a subject an effective amount of an agent that elevates SIRTI activity in endothelial cells of the subject, the invention further includes administering an NAD+ agonist or NAD+ precursor to a subject to increase vascular density and/or blood flow. The invention includes compositions comprising the said agent.

Abstract: A method for document transformation is provided. Documents for different types of transactions are obtained. Each document includes one or more form elements and each form element is represented by a data box to receive data from a user. A library of document templates is generated based on the obtained documents by assigning a common identifier to each of the form elements that match in the obtained documents and receiving a common definition for association with each of the matching form elements. At least a portion of the form elements in in one or more of the document templates are auto populated with the data values received from the user based on the identifiers associated with the form elements in the portion.

Abstract: Systems and methods for linking real world activity, such as real world commercial activity or real world data collection activity, with a location-based parallel reality game are provided. In particular, a game server hosting a parallel reality game can modify, update, or add to game data stored in a game database associated with the parallel reality game to include certain game features in the parallel reality game linked with real world activity in the real world. The game features can be linked with activities in the real world such that player actions associated with the game features in the virtual world can lead to or encourage activity in the real world, such as commercial activity and/or data collection activity in the real world. A one-time password may be used to validate a player's location in the real world and to enable controlled access to game features in the virtual world.

Abstract: A system and method for document transformation and recordation is provided. Documents for a transaction of real property are identified based on a jurisdiction in which the real property is located. Each document includes a plurality of data fields and each data field is associated with a data field identifier. A data value is received in at least one of the data fields of one or more of the documents. The data fields in the documents associated with the data field identifiers that match the data field identifiers of the data fields in which the data values are received are identified. The identified data fields are automatically populated with the data values based on the data field identifiers associated with the data values. A completeness rule is applied to the documents by verifying whether all required documents for completing the transaction in the jurisdiction are satisfied by the documents.