Abstract: A system and method for document transformation and compliance are provided. Document templates are maintained and each template includes data fields each associated with a data field identifier. Data values are received in one or more of the data fields of at least one document template. The data values are associated with the data fields into which the data values are received via the data field identifiers for those data fields. A property address is received and a set of compliance rules is identified. A subset of the document templates are retrieved as active documents for a transaction of the property based on the identified rules. The active documents are populated with those data fields that are associated with the linked data values via the data field identifiers. Compliance checking of the populated data values in the active documents is performed using a compliance rule set.

Abstract: A method for listing document transformation and recordation is provided. Documents relating to a real estate listing are identified and each document includes data fields associated with data field identifiers. A data value is received from a user in at least one of the data fields. A data model includes the data values received from the user and the data field identifiers of the data fields for which the data values are received is generated. The data fields associated with data field identifiers that match the data field identifiers of the data fields in which the data values are received are identified and populated with the data values. One or more correctness rules to be applied to the populated data fields of the documents are identified and applied to the documents by verifying that the data values populating the data fields are verified by one or more authoritative sources.

Abstract: A shared virtual experience is provided to players of a location-based game. The virtual location of a player in the game is based on the real world location of the player's client device. If a player's location in the game is within an interaction distance of a virtual element, in indication that a shared virtual experience is available may be provided. Player input is received requesting participation in the shared virtual experience and the player is added to a lobby including a specified start time. At the specified time, the shared virtual experience begins and includes interaction with other players who were in the lobby. An update to game data is sent based on an outcome of the shared virtual experience.

Abstract: A single-tier blockchain-based method for document transformation and accountability via different node types is provided. Document templates relating to a transfer of real property are maintained. Each template includes form elements each associated with a data field identifier. A subset of the document templates are collected as transaction documents for a transaction of a real property transfer. The form elements of the transaction documents are populated with received data values via the data field identifiers of the form elements. Compliance checking is performed on the populated data values of the transaction documents. A cryptographic hash of the transaction documents is provided to a network of nodes, which includes nodes that store different types of data related to the transaction documents. The cryptographic hash of the transaction documents is committed to a blockchain stored by one or more of the nodes in the network.

Abstract: A method includes selecting, by one or more servers, a digital component to be presented in an application executed at a client device; obtaining, by the one or more servers, attributes of the digital component, including at least one or more of a destination network location to which the digital component redirects users in response to interaction with the digital component and a reporting network location to which the interaction with the digital component is reported; after selecting the digital component and obtaining the attributes of the digital component, selecting, by the one or more servers and based on the obtained attributes, a config file that specifies a set of operations to be performed by the client device that presents the digital component; and transmitting, to the client device, a payload that includes information specifying the digital component to be presented in the application and the config file that, upon execution by the client device, causes the client device to perform the set of op

Abstract: The present invention relates to pharmaceutical compounds of the Formula (I), or a pharmaceutically acceptable salt or composition thereof, and methods of their use for the treatment of pain, respiratory conditions, as well as inhibiting the Transient Receptor Potential A1 ion channel (TRPA1).

Abstract: A method for listing document transformation and recordation is provided. Listing documents are selected from a library for a property listing. Data values are received via at least one of the listing documents. Relevant data fields within at least one listing document is updated with the received data values. Disclosure information regarding the property is received and further listing documents are added to the listing documents based on the disclosure information to form an active document set. Listing compliance rules are applied to the set of active documents to determine compliance. The active documents are recorded as a data block and provided to a tier of supernodes. The data block is added to a ledger of transactions via one of the supernodes. A copy of the data block is stored on each supernode. An immutable record of the data block is committed to a further tier of nodes.

Abstract: A method includes selecting, by one or more servers, a digital component to be presented in an application executed at a client device; obtaining, by the one or more servers, attributes of the digital component, including at least one or more of a destination network location to which the digital component redirects users in response to interaction with the digital component and a reporting network location to which the interaction with the digital component is reported; after selecting the digital component and obtaining the attributes of the digital component, selecting, by the one or more servers and based on the obtained attributes, a config file that specifies a set of operations to be performed by the client device that presents the digital component; and transmitting, to the client device, a payload that includes information specifying the digital component to be presented in the application and the config file that, upon execution by the client device, causes the client device to perform the set of op

Abstract: A method includes selecting, by one or more servers, a digital component to be presented in an application executed at a client device; obtaining, by the one or more servers, attributes of the digital component, including at least one or more of a destination network location to which the digital component redirects users in response to interaction with the digital component and a reporting network location to which the interaction with the digital component is reported; after selecting the digital component and obtaining the attributes of the digital component, selecting, by the one or more servers and based on the obtained attributes, a config file that specifies a set of operations to be performed by the client device that presents the digital component; and transmitting, to the client device, a payload that includes information specifying the digital component to be presented in the application and the config file that, upon execution by the client device, causes the client device to perform the set of op

Abstract: Systems and methods for detecting and preventing cheating in a location-based game are provided. In particular, a server-side statistical cheat detection algorithm can be implemented upon receiving a player request to perform a game action. A given dataset describing the respective times and locations of previous game events performed by the player can be analyzed to determine a probability that such game events represent legitimate gameplay. The determined probability can affect whether the player-requested game action is effectuated or can influence a number of points awarded for completion of the game action. An example system includes a host server and a client device in communication over a network.

Abstract: Methods and compositions for preventing or treating peripheral neuropathy, cognitive deficits, inactivity, depression, chemotherapy and/or radiotherapy induced peripheral neuropathy and cognitive deficits, and improving cognitive performance, in a subject in need thereof are disclosed. The disclosed methods include the step of administering to the subject an effective amount of an agent that increases the level of NAD+ in the subject.

Abstract: The present invention relates to pharmaceutical compounds of the Formula (I), or a pharmaceutically acceptable salt or composition thereof, and methods of their use for the treatment of pain, respiratory conditions, as well as inhibiting the Transient Receptor Potential A1 ion channel (TRPA1).

Abstract: The present invention relates to a method of increasing fertility, or reducing rate of decline in fertility, or restoring fertility, of a female subject, comprising administering to the subject an effective amount of an agent which elevates SIRT2 activity or SIRT2 expression, and to compositions and kits for increasing fertility, or reducing rate of decline in fertility, or restoring fertility.

Abstract: A shared virtual experience is provided to players of a location-based game. The virtual location of a player in the game is based on the real world location of the player's client device. If a player's location in the game is within an interaction distance of a virtual element, in indication that a shared virtual experience is available may be provided. Player input is received requesting participation in the shared virtual experience and the player is added to a lobby including a specified start time. At the specified time, the shared virtual experience begins and includes interaction with other players who were in the lobby. An update to game data is sent based on an outcome of the shared virtual experience.

Abstract: Systems and methods for linking real world activity, such as real world commercial activity or real world data collection activity, with a location-based parallel reality game are provided. In particular, a game server hosting a parallel reality game can modify, update, or add to game data stored in a game database associated with the parallel reality game to include certain game features in the parallel reality game linked with real world activity in the real world. The game features can be linked with activities in the real world such that player actions associated with the game features in the virtual world can lead to or encourage activity in the real world, such as commercial activity and/or data collection activity in the real world. A one-time password may be used to validate a player's location in the real world and to enable controlled access to game features in the virtual world.

Abstract: A shared virtual experience is provided to players of a location-based game. The virtual location of a player in the game is based on the real world location of the player's client device. If a player's location in the game is within an interaction distance of a virtual element, in indication that a shared virtual experience is available may be provided. Player input is received requesting participation in the shared virtual experience and the player is added to a lobby including a specified start time. At the specified time, the shared virtual experience begins and includes interaction with other players who were in the lobby. An update to game data is sent based on an outcome of the shared virtual experience.

Abstract: Systems and methods for linking real world activity, such as real world commercial activity or real world data collection activity, with a location-based parallel reality game are provided. In particular, a game server hosting a parallel reality game can modify, update, or add to game data stored in a game database associated with the parallel reality game to include certain game features in the parallel reality game linked with real world activity in the real world. The game features can be linked with activities in the real world such that player actions associated with the game features in the virtual world can lead to or encourage activity in the real world, such as commercial activity and/or data collection activity in the real world. A one-time password may be used to validate a player's location in the real world and to enable controlled access to game features in the virtual world.

Abstract: A system and method for tagging and integrating event data into operational data with the aid of a digital computer is provided. A plurality of categories of tags are maintained, each of the categories comprising a plurality of tags. A note comprising data about an event from a user is received. One or more of the tags are assigned to the note based on the user and the data. One or more of the tags is received from the user and the note is tagged with the received tags. Operational data comprising workflow data of an objective nature is defined. The note is integrated into the workflow data using the received tags, the assigned tags, and the categories of the received tags and the assigned tags. The workflow data with the integrated note is displayed on a display.

Abstract: Methods and compositions for preventing or treating peripheral neuropathy, cognitive deficits, inactivity, depression, chemotherapy and/or radiotherapy induced peripheral neuropathy and cognitive deficits, and improving cognitive performance, in a subject in need thereof are disclosed. The disclosed methods include the step of administering to the subject an effective amount of an agent that increases the level of NAD+ in the subject.

Abstract: Systems and methods for detecting and preventing cheating in a location-based game are provided. In particular, a server-side statistical cheat detection algorithm can be implemented upon receiving a player request to perform a game action. A given dataset describing the respective times and locations of previous game events performed by the player can be analyzed to determine a probability that such game events represent legitimate gameplay. The determined probability can affect whether the player-requested game action is effectuated or can influence a number of points awarded for completion of the game action. An example system includes a host server and a client device in communication over a network.