Patents by Inventor Ejner Knud Moltzen

Ejner Knud Moltzen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Phenyl-Piperazine Derivatives As Serotonin Reuptake Inhibitors
    Publication number: 20210276966
    Abstract: The invention provides compounds represented by the general formula I wherein the substituents are defined in the application. The compounds are useful in the treatment of an affective disorder, including depression, anxiety disorders including general anxiety disorder and panic disorder and obsessive compulsive disorder.
    Type: Application
    Filed: October 22, 2020
    Publication date: September 9, 2021
    Inventors: Thomas Ruhland, Garrick Paul Smith, Benny Bang-Andersen, Ask Puschl, Ejner Knud Moltzen, Kim Andersen
  • Phenyl-piperazine derivatives as serotonin reuptake inhibitors
    Patent number: 10844029
    Abstract: The invention provides compounds represented by the general formula I wherein the substituents are defined in the application. The compounds are useful in the treatment of an affective disorder, including depression, anxiety disorders including general anxiety disorder and panic disorder and obsessive compulsive disorder.
    Type: Grant
    Filed: June 15, 2017
    Date of Patent: November 24, 2020
    Assignee: H. Lundbeck A/S
    Inventors: Thomas Ruhland, Garrick Paul Smith, Benny Bang-Andersen, Ask Puschl, Ejner Knud Moltzen, Kim Andersen
  • Phenyl-Piperazine Derivatives As Serotonin Reuptake Inhibitors
    Publication number: 20180127389
    Abstract: The invention provides compounds represented by the general formula I wherein the substituents are defined in the application. The compounds are useful in the treatment of an affective disorder, including depression, anxiety disorders including general anxiety disorder and panic disorder and obsessive compulsive disorder.
    Type: Application
    Filed: June 15, 2017
    Publication date: May 10, 2018
    Inventors: Thomas Ruhland, Garrick Paul Smith, Benny Bang-Andersen, Ask Puschl, Ejner Knud Moltzen, Kim Andersen
  • Phenyl-piperazine derivatives as serotonin reuptake inhibitors
    Patent number: 9708280
    Abstract: The invention provides compounds represented by the general formula I wherein the substituents are defined in the application. The compounds are useful in the treatment of an affective disorder, including depression, anxiety disorders including general anxiety disorder and panic disorder and obsessive compulsive disorder.
    Type: Grant
    Filed: June 19, 2015
    Date of Patent: July 18, 2017
    Assignee: H. Lundbeck A/S
    Inventors: Thomas Ruhland, Garrick Paul Smith, Benny Bang-Andersen, Ask Puschl, Ejner Knud Moltzen, Kim Andersen
  • Phenyl-Piperazine Derivatives As Serotonin Reuptake Inhibitors
    Publication number: 20160137620
    Abstract: The invention provides compounds represented by the general formula I wherein the substituents are defined in the application. The compounds are useful in the treatment of an affective disorder, including depression, anxiety disorders including general anxiety disorder and panic disorder and obsessive compulsive disorder.
    Type: Application
    Filed: June 19, 2015
    Publication date: May 19, 2016
    Inventors: Thomas Ruhland, Garrick Paul Smith, Benny Bang-Andersen, Ask Puschl, Ejner Knud Moltzen, Kim Andersen
  • PHENYL-PIPERAZINE DERIVATIVES AS SEROTONIN REUPTAKE INHIBITORS
    Publication number: 20120302553
    Abstract: The invention provides compounds represented by the general formula I wherein the substituents are defined in the application. The compounds are useful in the treatment of an affective disorder, including depression, anxiety disorders including general anxiety disorder and panic disorder and obsessive compulsive disorder.
    Type: Application
    Filed: February 6, 2012
    Publication date: November 29, 2012
    Applicant: H. LUNDBECK A/S
    Inventors: Thomas Ruhland, Garrick P. Smith, Benny Bang-Anderson, Ask Puschl, Ejner Knud Moltzen, Kim Andersen
  • Phenyl-piperazine derivatives as serotonin reuptake inhibitors
    Patent number: 8110567
    Abstract: The invention provides compounds represented by the general formula I wherein the substituents are defined in the application. The compounds are useful in the treatment of an affective disorder, including depression, anxiety disorders including general anxiety disorder and panic disorder and obsessive compulsive disorder.
    Type: Grant
    Filed: February 4, 2010
    Date of Patent: February 7, 2012
    Assignee: H. Lundbeck A/S
    Inventors: Thomas Ruhland, Garrick Paul Smith, Benny Bang-Andersen, Ejner Knud Moltzen, Kim Andersen, Ask Puschl
  • Phenyl-piperazine derivatives as serotonin reuptake inhibitors
    Patent number: 7683053
    Abstract: The invention provides compounds represented by the general formula I wherein the substituents are defined in the application. The compounds are useful in the treatment of an affective disorder, including depression, anxiety disorders including general anxiety disorder and panic disorder and obsessive compulsive disorder.
    Type: Grant
    Filed: October 19, 2006
    Date of Patent: March 23, 2010
    Assignee: H. Lundbeck A/S
    Inventors: Thomas Ruhland, Garrick Paul Smith, Benny Bang-Andersen, Ejner Knud Moltzen, Kim Andersen
  • Heteroaryl derivates, their preparation and use
    Patent number: 7393845
    Abstract: A heteroaryl derivative having the formula (I).
    Type: Grant
    Filed: June 5, 2007
    Date of Patent: July 1, 2008
    Assignee: H. Lundbeck A/S
    Inventors: Mario Rottländer, Ejner Knud Moltzen, Ivan Mikkelsen, Thomas Ruhland, Kim Andersen, Christian Krog-Jensen
  • Indole derivatives
    Patent number: 7342015
    Abstract: A heteroaryl derivative having the formula (I).
    Type: Grant
    Filed: June 27, 2002
    Date of Patent: March 11, 2008
    Assignee: H. Lundbeck A/S
    Inventors: Mario Rottländer, Ejner Knud Moltzen, Ivan Mikkelsen, Thomas Ruhland, Kim Andersen, Christian Krog-Jensen
  • Phenyl-piperazine derivatives as serotonin reuptake inhibitors
    Patent number: 7144884
    Abstract: The invention provides compounds represented by the general formula I wherein the substituents are defined in the application.
    Type: Grant
    Filed: October 2, 2002
    Date of Patent: December 5, 2006
    Assignee: H. Lundbeck A/S
    Inventors: Thomas Ruhland, Garrick Paul Smith, Benny Bang-Andersen, Ask Puschl, Ejner Knud Moltzen, Kim Andersen
  • Phenyl-piperazine derivatives as serotonin reuptake inhibitors
    Patent number: 7138407
    Abstract: The invention provides compounds represented by the general formula I wherein the substituents are defined in the application. The compounds are useful in the treatment of an affective disorder, including depression, anxiety disorders including general anxiety disorder and panic disorder and obsessive compulsive disorder.
    Type: Grant
    Filed: December 6, 2005
    Date of Patent: November 21, 2006
    Assignee: H. Lundbeck A/S
    Inventors: Thomas Ruhland, Garrick Paul Smith, Benny Bang-Andersen, Ask Puschl, Ejner Knud Moltzen, Kim Andersen
  • Compounds and their use as glycine transport inhibitors
    Patent number: 6921774
    Abstract: The invention provides novel compounds of the formula I below: wherein the meaning of each substituent is defined in the application. The compounds are useful as inhibitors of the glycine transporter and useful in the treatment of diseases responsive to the inhibition of the glycine transporter. The invention provides a pharmaceutical composition comprising a compound of Formula I as defined above and the use of compounds as above for the manufacture of medicaments for treatment of diseases responsive to ligands of the glycine transporter.
    Type: Grant
    Filed: January 17, 2003
    Date of Patent: July 26, 2005
    Assignee: H. Lundbeck A/S
    Inventors: Ejner Knud Moltzen, Paul Garrick Smith, Christian Krog-Jensen, Klaus Peter Bøgesø
  • Indole and 2,3-dihydroindole derivatives, their preparation and use
    Patent number: 6727263
    Abstract: The present invention relates to indole and 2,3-dihydroindole derivatives having formula (I) or any of its any of its enantiometers or any mixture thereof, or an acid addition salt thereof, wherein A, R1, R2, R3, W, X, Y and Z are as described in the description. The compounds are potent serotonin reuptake inhibitors and have 5-HT1A receptor antagonistic activity.
    Type: Grant
    Filed: August 16, 2002
    Date of Patent: April 27, 2004
    Assignee: H. Lundbeck A/S
    Inventors: Ejner Knud Moltzen, Jens Kristian Perregaard, Ivan Mikkelsen, Garrick Paul Smith
  • Substituted phenyl-piperazine derivatives, their preparation and use
    Patent number: 6699864
    Abstract: The present invention provides compounds of the formula: wherein R1-R8, X, Y, Z, n and m are defined in the application. The compounds of the invention have affinity for the 5-HT1A receptor.
    Type: Grant
    Filed: June 20, 2002
    Date of Patent: March 2, 2004
    Assignee: H. Lundbeck A/S
    Inventors: Thomas Ruhland, Christian Krog-Jensen, Mario Rottländer, Gitte Mikkelsen, Ejner Knud Moltzen, Kim Andersen
  • Novel compounds and their use as glycine transport inhibitors
    Publication number: 20030181445
    Abstract: The invention provides novel compounds of the formula I below: 1
    Type: Application
    Filed: January 17, 2003
    Publication date: September 25, 2003
    Applicant: H. Lundbeck A/S
    Inventors: Ejner Knud Moltzen, Garrick Paul Smith, Christian Krog-Jensen, Klaus Peter Bogeso
  • Piperidine, tetrahydropyridine and piperazine derivatives, their preparation and use
    Patent number: 6596722
    Abstract: A piperidine, tetrahydropyridine or piperazine derivative having formula (I), any of its enantiomers or any mixture thereof, or an acid addition salt thereof, wherein B is C1-10-alkylene, C1-10-alkenylene or C1-10-alkynylene; X is —O—, —S—, or CR4R5—; and Y is —CR6R7, —CR6R7—CR8R9, or CR6═CR7—; or X and Y together form a group —CR4═CR5, or —CR4—CR5—CR6R7-; Z is —O—, or —S—; W is N, C, or CH, and the dotted line is an optional bond; A is a bicyclic ring selected from (Ia) or (Ib) wherein E1, E2 and E3 are selected from O, S, N, NR11, C, CR12 and CHR13, and the dotted line indicates an optional bond, provided that E2 and E1 and/or E3 may not simultaneously be O, or S.
    Type: Grant
    Filed: July 9, 2001
    Date of Patent: July 22, 2003
    Assignee: H. Lundbeck A/S
    Inventors: Ejner Knud Moltzen, Christian Krog-Jensen, Berith Bjørnholm
  • Substituted phenyl-piperazine derivatives, their preparation and use
    Publication number: 20030125320
    Abstract: The present invention provides compounds of the formula: 1
    Type: Application
    Filed: June 20, 2002
    Publication date: July 3, 2003
    Applicant: H. Lundbeck A/S
    Inventors: Thomas Ruhland, Christian Krog-Jensen, Mario Rottlander, Gitte Mikkelsen, Ejner Knud Moltzen, Kim Andersen
  • Novel indole derivatives
    Publication number: 20030050307
    Abstract: The invention provide compounds of the formula 1
    Type: Application
    Filed: June 25, 2002
    Publication date: March 13, 2003
    Applicant: H. Lundbeck A/S
    Inventors: Thomas Ruhland, Christian Krog-Jensen, Mario Rottlander, Gitte Mikkelsen, Kim Andersen, Ejner Knud Moltzen
  • Novel heteroaryl derivatives, their preparation and use
    Publication number: 20030050306
    Abstract: A heteroaryl derivative having the formula (I) 1
    Type: Application
    Filed: June 25, 2002
    Publication date: March 13, 2003
    Applicant: H. Lundbeck A/S
    Inventors: Thomas Ruhland, Christian Krog-Jensen, Ivan Mikkelsen, Mario Rottlander, Gitte Mikkelsen, Ejner Knud Moltzen, Kim Andersen