Patents by Inventor Elizabeth Jayne Wallace

Elizabeth Jayne Wallace has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • MUTANT LYSENIN PORES
    Publication number: 20180208632
    Abstract: The invention relates to mutant forms of lysenin. The invention also relates to analyte characterisation using lysenin.
    Type: Application
    Filed: August 31, 2017
    Publication date: July 26, 2018
    Applicant: Oxford Nanopore Technologies Ltd.
    Inventors: Mark Bruce, James Anthony Clarke, Andrew John Heron, Lakmal Jayasinghe, Elizabeth Jayne Wallace
  • MODIFIED ENZYMES
    Publication number: 20180179500
    Abstract: The invention relates to modified Dda helicases which can be used to control the movement of polynucleotides and are particularly useful for sequencing polynucleotides.
    Type: Application
    Filed: October 6, 2015
    Publication date: June 28, 2018
    Applicant: Oxford Nanopore Technologies Ltd.
    Inventors: Andrew John Heron, Rebecca Victoria Bowen, Mark Bruce, Lakmal Jayasinghe, Joseph Hargreaves Lloyd, Szabolcs Soeroes, Elizabeth Jayne Wallace, Christopher Peter Youd
  • MUTANT CSGG PORES
    Publication number: 20180148481
    Abstract: The invention relates to mutant forms of CsgG. The invention also relates to analyte detection and characterisation using CsgG.
    Type: Application
    Filed: September 1, 2015
    Publication date: May 31, 2018
    Applicants: Oxford Nanopore Technologies Ltd., VIB VZW, Vrije Universiteit Brussel
    Inventors: Stefan Howorka, Han Remaut, Lakmal Jayasinghe, Elizabeth Jayne Wallace, James Anthony Clarke, Richard George Hambley, Jonathan Bankes Pugh
  • MODIFIED HELICASES
    Publication number: 20180037874
    Abstract: The invention relates to a new method of characterising a target polynucleotide. The method uses a pore and a Dda helicase. The helicase controls the movement of the target polynucleotide through the pore. The invention also relates to modified Dda helicases which can be used to control the movement of polynucleotides and are particularly useful for sequencing polynucleotides.
    Type: Application
    Filed: September 10, 2014
    Publication date: February 8, 2018
    Applicant: Oxford Nanopore Technologies Ltd.
    Inventors: Mark Bruce, Andrew John Heron, Ruth Moysey, Szabolcs Soeroes, Elizabeth Jayne Wallace, James White
  • HETERO-PORES
    Publication number: 20180030526
    Abstract: The invention relates to hetero-oligomeric pores derived from Msp. The invention also relates to polynucleotide characterisation using the hetero-oligomeric pores.
    Type: Application
    Filed: February 17, 2016
    Publication date: February 1, 2018
    Applicant: Oxford Nanopore Technologies Ltd.
    Inventors: Clive Gavin Brown, James Anthony Clarke, Richard George Hambley, Andrew John Heron, Lakmal Jayasinghe, John Milton, Jonathan Bankes Pugh, Elizabeth Jayne Wallace
  • MUTANT PORES
    Publication number: 20170356037
    Abstract: The invention relates to mutant forms of Msp. The invention also relates to polynucleotide characterisation using Msp.
    Type: Application
    Filed: May 1, 2015
    Publication date: December 14, 2017
    Applicant: Oxford Nanopore Technologies Ltd.
    Inventors: James Anthony Clarke, Andrew John Heron, Lakmal Jayasinghe, Elizabeth Jayne Wallace
  • MUTANT PORES
    Publication number: 20170306398
    Abstract: The invention relates to mutant forms of Msp. The invention also relates to polynucleotide characterisation using Msp.
    Type: Application
    Filed: October 6, 2015
    Publication date: October 26, 2017
    Applicant: Oxford Nanopore Technologies Ltd.
    Inventors: Lakmal Jayasinghe, Elizabeth Jayne Wallace, Jonathan Bankes Pugh, Richard George Hambley, Neil Roger Wood, Andrew John Heron, James White
  • Enzyme construct
    Patent number: 9797009
    Abstract: The invention relates to methods using constructs comprising a helicase and an additional polynucleotide binding moiety. The helicase is attached to the polynucleotide binding moiety and the construct has the ability to control the movement of a polynucleotide. The constructs can be used to control the movement of polynucleotides and are particularly useful for sequencing polynucleotides.
    Type: Grant
    Filed: July 18, 2013
    Date of Patent: October 24, 2017
    Assignee: Oxford Nanopore Technologies Limited
    Inventors: Andrew Heron, James Clarke, Ruth Moysey, Elizabeth Jayne Wallace, Mark Bruce, Lakmal Jayasinghe, Domenico Caprotti, Szabolcs Soeroes, Luke McNeill, Mihaela Misca
  • MUTANT CSGG PORES
    Publication number: 20170283470
    Abstract: The invention relates to mutant forms of the outer membrane located lipoprotein CsgG, in particular, modifications at one or more of positions Tyr51; Asn55; and Phe56. The invention also relates to analyte detection and characterisation using said mutant CsgG.
    Type: Application
    Filed: September 1, 2015
    Publication date: October 5, 2017
    Applicants: Oxford Nanopore Technologies Ltd., VIB VZW, Vrije Universiteit Brussel
    Inventors: Stefan Howorka, Han Remaut, Lakmal Jayasinghe, Elizabeth Jayne Wallace, James Anthony Clarke, Richard George Hambley, Jonathan Bankes Pugh
  • Mutant lysenin pores
    Patent number: 9777049
    Abstract: The invention relates to mutant forms of lysenin. The invention also relates to analyte characterization using lysenin.
    Type: Grant
    Filed: March 15, 2013
    Date of Patent: October 3, 2017
    Assignee: Oxford Nanopore Technologies Ltd.
    Inventors: Mark Bruce, James Clarke, Andrew Heron, Lakmal Jayasinghe, Elizabeth Jayne Wallace
  • Mutant pores
    Patent number: 9751915
    Abstract: The invention relates to mutant forms of Msp. The invention also relates to nucleic acid characterization using Msp.
    Type: Grant
    Filed: February 10, 2012
    Date of Patent: September 5, 2017
    Assignee: Oxford Nanopore Technologies Ltd.
    Inventors: James Clarke, Andrew John Heron, Lakmal Jayasinghe, Elizabeth Jayne Wallace, James White
  • METHOD OF IMPROVING THE MOVEMENT OF A TARGET POLYNUCLEOTIDE WITH RESPECT TO A TRANSMEMBRANE PORE
    Publication number: 20170058338
    Abstract: The invention relates to improving the movement of a target polynucleotide with respect to a transmembrane pore when the movement is controlled by a polynucleotide binding protein. The invention also relates to improved transmembrane pores and polynucleotide binding proteins.
    Type: Application
    Filed: May 1, 2015
    Publication date: March 2, 2017
    Applicant: Oxford Nanopore Technologies Ltd.
    Inventors: Lakmal Jayasinghe, Elizabeth Jayne Wallace, Jonathan Bankes Pugh, Richard George Hambley, Neil Roger Wood, Clive Gavin Brown, James White
  • MUTANT PORES
    Publication number: 20170058337
    Abstract: The invention relates to mutant forms of Msp. The invention also relates to polynucleotide characterisation using Msp.
    Type: Application
    Filed: May 1, 2015
    Publication date: March 2, 2017
    Applicant: Oxford Nanopore Technologies Ltd. Oxford Nanapore TEchnologies Lomited
    Inventors: James Anthony Clarke, Andrew John Heron, Lakmal Jayasinghe, Elizabeth Jayne Wallace
  • METHOD FOR CONTROLLING THE MOVEMENT OF A POLYNUCLEOTIDE THROUGH A TRANSMEMBRANE PORE
    Publication number: 20170002406
    Abstract: The invention relates to new methods of controlling the movement of polynucleotides through transmembrane pores. The invention also relates to new methods of characterising target polynucleotides using helicases.
    Type: Application
    Filed: September 10, 2014
    Publication date: January 5, 2017
    Applicant: Oxford Nanopore Technologies Ltd.
    Inventors: Rebecca Victoria Bowen, Clive Gavin Brown, Mark Bruce, Andrew John Heron, Elizabeth Jayne Wallace, James White, Joseph Hargreaves Lloyd, David Antoni Alves, Domenico Caprotti, Lakmal Jayasinghe, Luke McNeill, John Milton, Antonino Puglisi, Szabolcs Soeroes
  • MODIFIED HELICASES
    Publication number: 20160257942
    Abstract: The invention relates to a new method of characterising a target polynucleotide. The method uses a pore and a Dda helicase. The helicase controls the movement of the target polynucleotide through the pore. The invention also relates to modified Dda helicases which can be used to control the movement of polynucleotides and are particularly useful for sequencing polynucleotides.
    Type: Application
    Filed: September 10, 2014
    Publication date: September 8, 2016
    Applicant: Oxford Nanopore Technologies Ltd.
    Inventors: Mark Bruce, Andrew John Heron, Ruth Moysey, Szabolcs Soeroes, Elizabeth Jayne Wallace, James White
  • ENZYME CONSTRUCT
    Publication number: 20150218629
    Abstract: The invention relates to methods using constructs comprising a helicase and an additional polynucleotide binding moiety. The helicase is attached to the polynucleotide binding moiety and the construct has the ability to control the movement of a polynucleotide. The constructs can be used to control the movement of polynucleotides and are particularly useful for sequencing polynucleotides.
    Type: Application
    Filed: July 18, 2013
    Publication date: August 6, 2015
    Inventors: Andrew Heron, James Clarke, Ruth Moysey, Elizabeth Jayne Wallace, Mark Bruce, Lakmal Jayasinghe, Domenico Caprotti, Szabolcs Soeroes, Luke McNeill, Mihaela Misca