Abstract: A glucose sensor includes a working electrode configured to provide a current signal (IsigWE1) based on a level of glucose, a background electrode configured to provide a current signal (IsigWE2) based on a presence of an excipient of insulin, and a controller. The controller is configured to monitor the IsigWE1 at the working electrode, monitor the IsigWE2 at the background electrode, monitor at least one electrochemical impedance spectroscopy (EIS) parameter at the working electrode, and calculate a change in the at least one EIS parameter, detect presence of the excipient of insulin based on the change. In a case where the presence of the excipient of insulin is detected, the controller is further configured to compensate the IsigWE1 based on a predetermined relationship between the IsigWE1 and the IsigWE2, and output the compensated IsigWE1 (IsigCOMP).

Abstract: A medical device includes a sensor to observe a characteristic of an anatomy, and a sensor base coupled to the sensor. The medical device includes a coupling system to couple the sensor base to the anatomy. The coupling system includes a first adhesive member and a second adhesive member. The first adhesive member is coupled to the sensor base and the second adhesive member is to couple to the anatomy. The first adhesive member includes at least one cut-out to direct moisture to an ambient environment surrounding the medical device.

Abstract: An infusion device configured to implant a cannula and a sensor in a user. The infusion device includes a first unit defining a first housing and a second unit defining a second housing. The second housing is configured to engage the first housing. The infusion device includes a first insertion needle configured to implant the cannula in the user and a second insertion needle configured to implant the sensor in the user when the second unit engages the first unit. The infusion device includes processing circuitry in electrical communication with the sensor and a fluid reservoir in fluid communication with the cannula. In examples, the first unit and the second unit are configured to engage using an inserter.

Abstract: A deployment device for deploying a transcutaneous sensor in accordance with an embodiment of the present technology includes a housing including a plunger, a frame, and a cap. The deployment device further includes a spring and a carrier within the housing. The frame defines a deployment window through which the carrier is configured to move the transcutaneous device into contact with a target surface of a subject. This can occur at least partially in response to the frame moving in a second direction relative to the plunger, the second direction being opposite the first direction. The deployment device also include a stop that, when engaged, is configured block separation of the cap from the plunger, thereby enabling the spring to be removed from the housing. The stop is configured to disengage at least partially in response to the frame moving in the second direction relative to the plunger.

Abstract: Removable devices wearable on a user's skin and methods for using such devices are provided. An exemplary removable device includes a skin adhesive configured to adhere to the skin, a durable component, and an interface component interconnecting the durable component and the skin adhesive. The device separates at the interface component to remove the durable component from the skin adhesive upon application of a removal force to the device.

Abstract: A medicine delivery and tracking system includes a medicine injection pen and a delivery port. The pen includes a needle through which medicine is dispensed and an electronic unit configured to at least one of log dispensing of medicine from the pen, control dispensing of medicine from the pen, or communicate regarding dispensing of medicine from the pen. Alternatively, the electronic unit may be part of a separate computing device. The delivery port is configured for attachment to a user and to receive the needle of the pen such that medicine dispensed from the pen is dispensed into the delivery port and through the delivery port to the user. The delivery port includes a detector mechanism configured to detect a presence of the pen and, in response thereto, to communicate a signal to the electronic unit for use in the at least one of logging, controlling, or communicating.

Abstract: A medical device includes a base having a first surface to be secured to a patient's skin. A first insertable member has a length portion extending from the first surface of the base for insertion. A second insertable member has a length portion extending from the first surface of the base for insertion through the patient's skin. The first insertable member includes a sensor member for sensing a biological condition, and the second insertable member includes an infusion cannula for infusing an infusion media. The distal end of the first insertable member and the distal end of the second insertable member are spaced apart by a first distance of at least 5.0 mm, for reducing interference of the infusion media from the infusion cannula with an operation of the sensor member.

Abstract: A temporary pacing lead device comprises: an elongate body having a distal portion and a proximal end; an electrode array at the distal portion configured to deliver a pacing signal to target tissue; a displacement member attached to a first side of the distal portion; at least one anchoring element deployable from a second opposite side; and an interface at the proximal end of the elongate body. The interface is configured to couple to a pacing signal generator and/or a control handle to actuate the displacement member and/or anchoring element. The pacing generator can be a miniature pacing signal generator and/or a standard pacemaker device, and the interface can switch between providing the pacing signal from either of the two sources. The miniature pacing signal generator can include a protective element for the control and/or actuation elements at the proximal end.

Abstract: A method for compensating for a life-lengthening agent for a glucose sensor includes accessing first and second electrochemical impedance spectroscopy (EIS) values of at least one parameter based on first and second EIS procedures performed on EIS signals from a working electrode of the glucose sensor, calculating a change in the at least one parameter between the first and second EIS values, estimating a concentration of the agent based on the change in the at least one parameter, and calculating a model effect in response to the concentration. In a case where the model effect is not greater than the threshold, the method further includes adjusting a sensor glucose value based on the concentration and sensor signals from the working electrode, and displaying the adjusted sensor glucose value.

Abstract: An example device includes an electrochemical cell configured to generate a first electrical signal indicative of an amount of glucose in a fluid of a person, the electrochemical cell comprising a working electrode, a counter electrode, and a reference electrode; and a background electrode configured to not catalyze a reaction with glucose and is configured to generate a second electrical signal indicative of an amount of electrochemical interference proximate the electrochemical cell.

Abstract: Removable devices wearable on a user's skin and methods for using such devices are provided. An exemplary removable device includes a skin adhesive configured to adhere to the skin, a durable component, and an interface component interconnecting the durable component and the skin adhesive. The device separates at the interface component to remove the durable component from the skin adhesive upon application of a removal force to the device.

Abstract: In some embodiments, an apparatus may comprise a first insertion needle and a second insertion needle. The first insertion needle may be configured to carry a first medical device (e.g., a sensor) through an opening in an apparatus housing. The second insertion needle may be configured to carry a second medical device (e.g., a cannula) along a curved path that passes through the opening in the apparatus housing such that a distal end of the first medical device becomes increasingly displaced from the distal end of the second medical device as the distal end of the second medical device is carried along the curved path.

Abstract: A disposable medical introduction system including a medical device and a disposable inserter. The disposable inserter includes a carrier to receive the medical device. The carrier includes at least one annular projection. The disposable inserter includes a retractor received within the at least one annular projection and movable relative to the at least one annular projection. The retractor has at least one retaining arm. The disposable inserter includes a needle cartridge coupled to the retractor that includes an insertion needle. The at least one retaining arm cooperates with the needle cartridge to maintain the insertion needle in a first, extended state. A movement of the retractor relative to the at least one annular projection releases the at least one retaining arm to move the insertion needle from the first, extended state to a second, retracted state.

Abstract: A sensor assembly for sensing a physiological characteristic includes a power source configured to deliver power to one or more components of an electrical subsystem upon deployment of the sensor assembly to a user. A power latch is configured to latch an output of a power control switch for delivery to one or more components of the electrical subsystem upon deployment of the sensor assembly to a user. The power control switch is configured to inhibit delivery of power to the electrical subsystem prior to deployment of the sensor assembly to a user and to deliver the latched output to one or more components of the electrical subsystem in response to deployment of the sensor assembly to a user.

Abstract: A sensor assembly for sensing a physiological characteristic includes a power source, a power control switch, and a power latch configured to latch an output of the power control switch. The sensor assembly also includes a power converter coupled to the power control switch. The power converter is configured to step down a voltage of the latched output of the power control switch for delivery of the latched output to one or more components of the sensor assembly. The power control switch is configured to inhibit consumption of power from the power source when the sensor assembly is in a pre-deployment state and output the latched output to the power converter in response to transition of the sensor assembly from the pre-deployment state to a deployed state.

Abstract: A fluid infusion system includes a housing configured to be adhesively coupled to an anatomy of a user, and a tube configured to extend from the housing for insertion into the anatomy of the user. The tube includes a plurality of conduits defined within the tube. The plurality of conduits include a fluid delivery conduit configured to facilitate a fluidic connection between a fluid source and the anatomy of the user, and one or more conduits configured to accommodate a plurality of electrodes for determining a physiological characteristic of the user.

Abstract: An insertion device configured to implant a first medical device and a second medical device in a user. The first medical device may be a fluid delivery cannula configured to deliver a fluid (e.g., insulin) to the user. The second medical device may be an analyte sensor (e.g., a glucose sensor) configured to detect a physiological characteristic of the user (e.g., a glucose level). The insertion device may be configured to be worn by the user. The insertion device includes a first linkage assembly configured to extend and retract a first insertion needle to implant the first medical device and a second linkage assembly configured to extend and retract a second insertion needle to implant the second medical device. The insertion device includes a user input device configured to cause the insertion device to initiate the implantation when activated by the user.

Abstract: Disclosed herein are techniques related to medicine administration in dynamic networks. The techniques may involve identifying an amount of medicine for delivery to a patient and determining a communication path toward a first medicine administration device of a plurality of medicine administration devices in a mesh network. The plurality of medicine administration devices may further include a second medicine administration device that is prioritized over the first medicine administration device for delivering medicine to the patient. The techniques may further involve causing delivery of the amount of medicine to the patient by the first medicine administration device based on communicating the amount of medicine toward the first medicine administration device via the communication path when the amount of medicine remains undelivered by the second medicine administration device.

Abstract: A system for a physiological characteristic sensor deployed with a sensor inserter includes an adhesive skin patch coupled to the physiological characteristic sensor. The adhesive patch is to couple the physiological characteristic sensor to an anatomy. The system also includes a gravity resistance system coupled to the adhesive patch and to be coupled to the sensor inserter. The gravity resistance system maintains the adhesive patch substantially perpendicular to a longitudinal axis of the sensor inserter prior to deployment of the physiological characteristic sensor and is removable from the adhesive patch by the sensor inserter upon deployment of the physiological characteristic sensor.

Abstract: The invention provides a skin adhesive patch that inhibits skin irritation by releasing an anti-inflammatory agent such as a corticosteroid topically on the skin surface. Embodiments of the invention can be adapted for use with a wide variety of adhesive patches that are used to couple medical components to the skin of patients such as the devices that diabetic patients use including insulin infusion sets, patch pumps, and all-in-one patch sets.